|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
1.000
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
1.000
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.999
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.997
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.996
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.989
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.986
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.978
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.976
|
Mouse |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.975
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.973
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.971
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.966
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.965
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.964
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.964
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.963
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.962
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.959
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.952
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.951
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.950
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.950
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.949
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.949
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
159 |
0.947
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.946
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.946
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.945
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.929
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.926
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.926
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.923
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.917
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.909
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.907
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.906
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.900
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.900
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.897
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.888
|
Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.887
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.876
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.872
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.870
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.864
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.864
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.861
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.855
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.853
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.840
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.839
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.839
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.825
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.821
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.820
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.819
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.816
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.809
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.804
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.804
|
Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.801
|
|
|
|
pml body organization
|
GO:0030578 |
2 |
0.801
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.797
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.795
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.793
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.790
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.785
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.784
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.778
|
Mouse |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.777
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.771
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.754
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.750
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.745
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.742
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.737
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.731
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.724
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.724
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.720
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.717
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.716
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.706
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.703
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.702
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.695
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.683
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.680
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.676
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.673
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.672
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.666
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.664
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.664
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.662
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.659
|
Mouse |
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.658
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.653
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.649
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.648
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.646
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.635
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.634
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.630
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.625
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.625
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.616
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.602
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.602
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.598
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.594
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.593
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.586
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.576
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.574
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.569
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.567
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.563
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.562
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.561
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.558
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.556
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.556
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.546
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.544
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.543
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.539
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.533
|
Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.527
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.522
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.520
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.519
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.512
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.509
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.506
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.502
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.502
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.502
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.499
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.497
|
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
12 |
0.496
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.493
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.489
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.487
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.481
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.470
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.465
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.464
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.464
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.461
|
Mouse |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.458
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.457
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.452
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.449
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.449
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.449
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.447
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.444
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.437
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.435
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.435
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.435
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.434
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.432
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.426
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.424
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.422
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.422
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.417
|
Mouse |
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.412
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.411
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.409
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.405
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.404
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.404
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.403
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.403
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.403
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.401
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.397
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.392
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.392
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.387
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.382
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.379
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.376
|
|
|
|
regulation of intracellular transport of viral material
|
GO:1901252 |
2 |
0.376
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.375
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.374
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.372
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.370
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.367
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.365
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.362
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.359
|
Mouse |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.356
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.355
|
|
|
|
aging
|
GO:0007568 |
66 |
0.355
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.355
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.355
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.348
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.337
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.337
|
Mouse |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.336
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.328
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.326
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.325
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.324
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.322
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.320
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.314
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.314
|
Mouse |
|
|
response to lipid
|
GO:0033993 |
206 |
0.312
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.311
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.309
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.305
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.305
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.301
|
Mouse |
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.299
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.299
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.299
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.297
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.294
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.294
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.292
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.292
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.291
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.291
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.287
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.284
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.283
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.283
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.280
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.280
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.280
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.279
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.274
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.274
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.272
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.272
|
Mouse |
|
|
gland development
|
GO:0048732 |
48 |
0.271
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.271
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.267
|
Mouse |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.264
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.262
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.261
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.261
|
Mouse |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.260
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.260
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.258
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.255
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.253
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.253
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.252
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.252
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.251
|
Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.247
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.246
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.243
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.241
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.240
|
|
|
|
calcium ion import
|
GO:0070509 |
23 |
0.239
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.239
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.238
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.238
|
Mouse |
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.234
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.232
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.230
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.229
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.226
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.222
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.222
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.222
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.221
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.219
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.219
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.216
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.214
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.213
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.212
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.212
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.212
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.209
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.209
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.208
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.206
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.204
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.204
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.202
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
26 |
0.196
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.194
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.193
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.193
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.192
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.190
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.190
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.188
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.187
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.185
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.185
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.184
|
Mouse |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.183
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.183
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.182
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.179
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.179
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.178
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.177
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.175
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.175
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.174
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.172
|
|
|
|
growth
|
GO:0040007 |
202 |
0.171
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.171
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.170
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.170
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.169
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.168
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.168
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.167
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.167
|
|
|
|
positive regulation of viral entry into host cell
|
GO:0046598 |
3 |
0.165
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.162
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.160
|
|
|
|
thyroid hormone metabolic process
|
GO:0042403 |
4 |
0.160
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.160
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.160
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.159
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.157
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.156
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.155
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.153
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.153
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.152
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.149
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.148
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.147
|
Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.147
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.146
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.144
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.144
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.144
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.141
|
|
|
|
head development
|
GO:0060322 |
108 |
0.141
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.141
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.141
|
Mouse |
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.139
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.139
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.139
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.138
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.138
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.137
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.137
|
Mouse |
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.137
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.134
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.134
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.134
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.134
|
|
|
|
entry into host
|
GO:0044409 |
25 |
0.133
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.133
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.132
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.132
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.132
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.131
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.130
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.130
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.129
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.129
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.128
|
Mouse |
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.128
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.126
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.126
|
Mouse |
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.125
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.125
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.125
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.124
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.124
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.123
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.123
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.122
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.122
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.122
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.122
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.122
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.121
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.121
|
Mouse |
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.120
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.120
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.118
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.117
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.117
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.116
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.115
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.114
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.114
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.114
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.113
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.113
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.113
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.113
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.113
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.112
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.111
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.110
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.110
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.109
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.109
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.109
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.108
|
|
|
|
thyroid hormone generation
|
GO:0006590 |
2 |
0.107
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.107
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.106
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.106
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.106
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.105
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.105
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.105
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.104
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.104
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.102
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.102
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.102
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.102
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.101
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.101
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.101
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.100
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.100
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.100
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.099
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.099
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.098
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.098
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.096
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.096
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.094
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.094
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.094
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.094
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.093
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.093
|
Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.093
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.093
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.091
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.091
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.090
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.089
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.089
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.089
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.088
|
|
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.088
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.087
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.086
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.086
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.085
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.085
|
|
|
|
negative regulation of calcium ion import
|
GO:0090281 |
1 |
0.085
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.085
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.084
|
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.084
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.083
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
9 |
0.083
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.083
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.082
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.082
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.082
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.082
|
Mouse |
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.081
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.081
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.081
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.081
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.080
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.080
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.079
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.079
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.078
|
Mouse |
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.078
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.078
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.077
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.077
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.077
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.076
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.076
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.075
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.075
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.075
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.075
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.074
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.074
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.073
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.073
|
|
