Homo sapiens

6 known processes

POLR1C

polymerase (RNA) I polypeptide C, 30kDa

(Aliases: RPA5,RPA39,RPAC1,RPA40,TCS3)

POLR1C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.990
Worm
rrna processing GO:0006364 35 0.783
ribosomal small subunit biogenesis GO:0042274 13 0.766
ncrna processing GO:0034470 83 0.709
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.609
ncrna metabolic process GO:0034660 108 0.597
pyrimidine ribonucleoside metabolic process GO:0046131 11 0.591
maturation of ssu rrna GO:0030490 3 0.567
rna processing GO:0006396 255 0.492
ribosome biogenesis GO:0042254 48 0.467
vesicle mediated transport GO:0016192 371 0.441
Worm
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 3 0.311
ribonucleoprotein complex biogenesis GO:0022613 116 0.302
receptor mediated endocytosis GO:0006898 84 0.249
Worm
pyrimidine ribonucleoside triphosphate metabolic process GO:0009208 2 0.216
pyrimidine ribonucleoside biosynthetic process GO:0046132 2 0.209
female gamete generation GO:0007292 2 0.202
endocytosis GO:0006897 159 0.202
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.201
nucleoside triphosphate metabolic process GO:0009141 422 0.197
cytoplasmic transport GO:0016482 379 0.180
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.149
oogenesis GO:0048477 2 0.148
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.146
nucleoside monophosphate metabolic process GO:0009123 191 0.128
negative regulation of developmental process GO:0051093 247 0.125
rrna modification GO:0000154 2 0.124
nucleoside triphosphate catabolic process GO:0009143 394 0.123
rrna metabolic process GO:0016072 40 0.120
embryo development GO:0009790 123 0.120
Worm
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 1 0.118
nervous system development GO:0007399 293 0.104
sex differentiation GO:0007548 45 0.099
reproductive structure development GO:0048608 55 0.097
purine ribonucleoside metabolic process GO:0046128 437 0.095
ribonucleoprotein complex assembly GO:0022618 78 0.091
regulation of interferon beta production GO:0032648 22 0.089
neurogenesis GO:0022008 169 0.088
cytokine production GO:0001816 247 0.086
carbohydrate derivative biosynthetic process GO:1901137 207 0.080
ribonucleoside catabolic process GO:0042454 406 0.079
single organism reproductive process GO:0044702 98 0.078
positive regulation of cytokine production GO:0001819 167 0.077
purine nucleoside triphosphate metabolic process GO:0009144 412 0.077
reproduction GO:0000003 63 0.076
regulation of cell development GO:0060284 161 0.075
development of primary sexual characteristics GO:0045137 35 0.075
purine nucleotide catabolic process GO:0006195 405 0.074
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.072
regulation of cell differentiation GO:0045595 393 0.070
reproductive process GO:0022414 106 0.068
regulation of cell cycle GO:0051726 393 0.067
negative regulation of protein metabolic process GO:0051248 391 0.063
developmental process involved in reproduction GO:0003006 66 0.063
gonad development GO:0008406 34 0.063
transcription from rna polymerase iii promoter GO:0006383 19 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.060
response to oxygen containing compound GO:1901700 369 0.059
purine ribonucleoside catabolic process GO:0046130 398 0.053
reproductive system development GO:0061458 56 0.052
gtp metabolic process GO:0046039 239 0.051
mrna metabolic process GO:0016071 175 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.047
dna replication GO:0006260 116 0.046
positive regulation of developmental process GO:0051094 314 0.046
regulation of growth GO:0040008 165 0.043
blastocyst development GO:0001824 3 0.043
negative regulation of multicellular organismal process GO:0051241 317 0.043
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
regulation of nervous system development GO:0051960 88 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
nuclear export GO:0051168 69 0.037
purine ribonucleotide catabolic process GO:0009154 404 0.035
protein localization to organelle GO:0033365 280 0.035
ribonucleoside monophosphate catabolic process GO:0009158 158 0.034
ribosomal large subunit biogenesis GO:0042273 10 0.034
positive regulation of cell development GO:0010720 92 0.032
single organism cellular localization GO:1902580 332 0.032
purine nucleoside monophosphate metabolic process GO:0009126 186 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
regulation of neurogenesis GO:0050767 82 0.031
pyrimidine nucleoside metabolic process GO:0006213 13 0.031
defense response GO:0006952 315 0.031
gtp catabolic process GO:0006184 237 0.031
regulation of cytokine production GO:0001817 232 0.030
ribose phosphate biosynthetic process GO:0046390 82 0.030
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.030
regulation of cell cycle process GO:0010564 266 0.030
type i interferon production GO:0032606 27 0.029
regulation of protein transport GO:0051223 213 0.029
nucleoside catabolic process GO:0009164 408 0.029
immune response GO:0006955 307 0.028
organelle assembly GO:0070925 176 0.028
atp metabolic process GO:0046034 176 0.028
ribonucleotide catabolic process GO:0009261 405 0.027
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.027
mitotic cell cycle GO:0000278 326 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.027
ribonucleotide biosynthetic process GO:0009260 81 0.027
cellular response to oxygen containing compound GO:1901701 276 0.027
organophosphate catabolic process GO:0046434 430 0.027
protein maturation GO:0051604 233 0.027
apoptotic signaling pathway GO:0097190 268 0.027
nucleoside monophosphate catabolic process GO:0009125 159 0.026
intracellular protein transport GO:0006886 270 0.026
pyrimidine nucleotide metabolic process GO:0006220 6 0.026
pyrimidine containing compound biosynthetic process GO:0072528 4 0.026
neuromuscular junction development GO:0007528 3 0.026
lipid metabolic process GO:0006629 381 0.026
pyrimidine containing compound metabolic process GO:0072527 19 0.025
negative regulation of immune system process GO:0002683 136 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
response to growth factor GO:0070848 205 0.025
regulation of cell migration GO:0030334 289 0.024
negative regulation of cell differentiation GO:0045596 171 0.024
negative regulation of apoptotic process GO:0043066 316 0.023
maturation of lsu rrna GO:0000470 3 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
mitochondrion organization GO:0007005 156 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
embryo development ending in birth or egg hatching GO:0009792 34 0.023
Worm
regulation of locomotion GO:0040012 329 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
regulation of multi organism process GO:0043900 157 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
generation of neurons GO:0048699 152 0.022
negative regulation of cell death GO:0060548 345 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.021
response to hormone GO:0009725 175 0.021
nuclear transport GO:0051169 179 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
rna modification GO:0009451 27 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
protein targeting GO:0006605 187 0.020
regulation of protein localization GO:0032880 296 0.020
regulation of immune response GO:0050776 201 0.020
mononuclear cell proliferation GO:0032943 71 0.020
atp catabolic process GO:0006200 157 0.020
regulation of cellular component biogenesis GO:0044087 281 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
positive regulation of growth GO:0045927 58 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
regulation of cellular response to stress GO:0080135 244 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
nucleotide catabolic process GO:0009166 408 0.018
rna splicing GO:0008380 131 0.018
pyrimidine ribonucleoside catabolic process GO:0046133 8 0.018
positive regulation of transport GO:0051050 336 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
nitrogen compound transport GO:0071705 191 0.017
regulation of nuclear division GO:0051783 65 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
cell growth GO:0016049 160 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
purine containing compound catabolic process GO:0072523 411 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
positive regulation of immune system process GO:0002684 283 0.016
negative regulation of protein processing GO:0010955 142 0.015
rna 5 end processing GO:0000966 2 0.015
protein oligomerization GO:0051259 173 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
innate immune response GO:0045087 178 0.014
negative regulation of protein modification process GO:0031400 200 0.014
protein localization to membrane GO:0072657 160 0.014
signal transduction by p53 class mediator GO:0072331 72 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
regulation of cell division GO:0051302 116 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
cell development GO:0048468 328 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
regulation of protein maturation GO:1903317 150 0.013
rna 3 end processing GO:0031123 35 0.013
cellular response to acid chemical GO:0071229 44 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
cell division GO:0051301 168 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
negative regulation of cell cycle GO:0045786 193 0.012
cell morphogenesis GO:0000902 296 0.012
lipid biosynthetic process GO:0008610 177 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
response to other organism GO:0051707 261 0.012
lymphocyte activation GO:0046649 133 0.012
t cell activation GO:0042110 99 0.012
regeneration GO:0031099 4 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
regulation of kinase activity GO:0043549 314 0.012
cell projection organization GO:0030030 252 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
response to nitrogen compound GO:1901698 184 0.012
positive regulation of catabolic process GO:0009896 310 0.012
protein homooligomerization GO:0051260 100 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
transcription from rna polymerase i promoter GO:0006360 11 0.012
positive regulation of interferon beta production GO:0032728 17 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
regulation of neuron differentiation GO:0045664 70 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
nuclear division GO:0000280 128 0.011
pyrimidine ribonucleotide metabolic process GO:0009218 4 0.011
blastocyst formation GO:0001825 3 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
mitotic cell cycle process GO:1903047 286 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
positive regulation of gliogenesis GO:0014015 4 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
immune effector process GO:0002252 159 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
positive regulation of defense response GO:0031349 87 0.010
pyrimidine nucleotide biosynthetic process GO:0006221 2 0.010
mitochondrial rna metabolic process GO:0000959 15 0.010

POLR1C disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
spinocerebellar degeneration DOID:2478 27 0.010
central nervous system disease DOID:331 186 0.010
neurodegenerative disease DOID:1289 102 0.010
nervous system disease DOID:863 431 0.010
treacher collins syndrome DOID:2908 3 0.000