Homo sapiens

55 known processes

POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

(Aliases: MGC75453,RPB1,RPOL2,RPO2,hsRPB1,POLRA,hRPB220,POLR2,RpIILS,RPBh1)

POLR2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of dna templated transcription elongation GO:0032786 18 0.999
regulation of dna templated transcription elongation GO:0032784 23 0.993
dna templated transcription elongation GO:0006354 25 0.989
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.970
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.956
dna repair GO:0006281 198 0.921
Yeast
nucleotide excision repair GO:0006289 31 0.908
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.895
cellular response to dna damage stimulus GO:0006974 379 0.858
Yeast Fly
cellular response to external stimulus GO:0071496 111 0.799
transcription coupled nucleotide excision repair GO:0006283 8 0.773
rna processing GO:0006396 255 0.757
histone modification GO:0016570 251 0.707
mrna metabolic process GO:0016071 175 0.687
mrna processing GO:0006397 133 0.649
chromatin organization GO:0006325 351 0.610
intracellular mrna localization GO:0008298 1 0.591
cellular response to nutrient levels GO:0031669 69 0.485
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.466
macroautophagy GO:0016236 39 0.447
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.412
immune system development GO:0002520 195 0.375
regulation of cellular amine metabolic process GO:0033238 11 0.359
amine metabolic process GO:0009308 44 0.344
hematopoietic or lymphoid organ development GO:0048534 186 0.338
covalent chromatin modification GO:0016569 254 0.336
nucleoside catabolic process GO:0009164 408 0.316
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.312
regulation of mrna metabolic process GO:1903311 53 0.296
protein dephosphorylation GO:0006470 81 0.290
regulation of cellular ketone metabolic process GO:0010565 50 0.281
cellular amine metabolic process GO:0044106 41 0.281
regulation of cellular amino acid metabolic process GO:0006521 6 0.273
tube development GO:0035295 125 0.269
Worm
positive regulation of cellular amine metabolic process GO:0033240 7 0.268
hemopoiesis GO:0030097 180 0.258
7 methylguanosine mrna capping GO:0006370 7 0.249
cellular response to starvation GO:0009267 58 0.243
purine ribonucleotide catabolic process GO:0009154 404 0.242
histone monoubiquitination GO:0010390 20 0.240
autophagy GO:0006914 88 0.233
atp metabolic process GO:0046034 176 0.216
rna localization GO:0006403 41 0.207
rna splicing GO:0008380 131 0.195
post embryonic development GO:0009791 2 0.189
Worm
dephosphorylation GO:0016311 209 0.186
organophosphate catabolic process GO:0046434 430 0.184
cellular response to extracellular stimulus GO:0031668 72 0.182
regulation of mrna 3 end processing GO:0031440 12 0.166
purine nucleotide catabolic process GO:0006195 405 0.160
regulation of ribosome biogenesis GO:0090069 1 0.158
regulation of response to external stimulus GO:0032101 222 0.158
positive regulation of protein kinase activity GO:0045860 190 0.156
regulation of kinase activity GO:0043549 314 0.154
nuclear division GO:0000280 128 0.153
Worm
response to extracellular stimulus GO:0009991 85 0.149
segmentation GO:0035282 4 0.147
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.144
cellular ketone metabolic process GO:0042180 80 0.140
regulation of transferase activity GO:0051338 355 0.138
myeloid cell differentiation GO:0030099 117 0.136
protein dna complex subunit organization GO:0071824 80 0.136
mitotic cell cycle GO:0000278 326 0.134
Worm Fly
rna 3 end processing GO:0031123 35 0.134
rna capping GO:0036260 10 0.133
regulation of cell differentiation GO:0045595 393 0.133
rrna metabolic process GO:0016072 40 0.133
positive regulation of transferase activity GO:0051347 227 0.129
positive regulation of cellular catabolic process GO:0031331 284 0.129
chromatin modification GO:0016568 298 0.125
ncrna processing GO:0034470 83 0.124
purine nucleoside monophosphate catabolic process GO:0009128 158 0.123
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.123
organelle fission GO:0048285 149 0.122
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.117
response to biotic stimulus GO:0009607 276 0.115
positive regulation of protein phosphorylation GO:0001934 313 0.113
response to nutrient levels GO:0031667 81 0.112
ribonucleoside catabolic process GO:0042454 406 0.112
positive regulation of kinase activity GO:0033674 204 0.111
positive regulation of response to external stimulus GO:0032103 88 0.110
response to starvation GO:0042594 59 0.106
nucleoside monophosphate metabolic process GO:0009123 191 0.105
ribonucleoside monophosphate metabolic process GO:0009161 187 0.105
regulation of rrna processing GO:2000232 1 0.104
rna polyadenylation GO:0043631 14 0.103
regulation of autophagy GO:0010506 52 0.103
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.101
regulation of chromatin organization GO:1902275 56 0.101
purine ribonucleoside metabolic process GO:0046128 437 0.101
response to radiation GO:0009314 151 0.099
generation of neurons GO:0048699 152 0.096
female gamete generation GO:0007292 2 0.093
somitogenesis GO:0001756 2 0.093
ribonucleoprotein complex biogenesis GO:0022613 116 0.092
transcription from rna polymerase i promoter GO:0006360 11 0.090
multicellular organismal aging GO:0010259 3 0.090
regulation of cellular component biogenesis GO:0044087 281 0.088
negative regulation of cell differentiation GO:0045596 171 0.087
nucleoside monophosphate catabolic process GO:0009125 159 0.087
response to other organism GO:0051707 261 0.086
ribonucleoside triphosphate catabolic process GO:0009203 391 0.085
nucleotide catabolic process GO:0009166 408 0.083
nucleoside triphosphate catabolic process GO:0009143 394 0.083
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.082
positive regulation of developmental process GO:0051094 314 0.082
macromolecule methylation GO:0043414 97 0.080
Worm
transcription from rna polymerase iii promoter GO:0006383 19 0.080
positive regulation of mrna 3 end processing GO:0031442 12 0.077
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.076
chromatin assembly or disassembly GO:0006333 78 0.075
protein ubiquitination GO:0016567 314 0.074
negative regulation of multicellular organismal process GO:0051241 317 0.072
rna export from nucleus GO:0006405 33 0.071
positive regulation of cellular component biogenesis GO:0044089 158 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.067
protein monoubiquitination GO:0006513 39 0.067
regulation of dna repair GO:0006282 47 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.066
cellular amino acid metabolic process GO:0006520 116 0.066
response to abiotic stimulus GO:0009628 336 0.066
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.066
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.065
regulation of response to dna damage stimulus GO:2001020 94 0.064
cytoplasmic transport GO:0016482 379 0.064
purine nucleoside triphosphate catabolic process GO:0009146 392 0.064
regulation of chromatin modification GO:1903308 51 0.062
rrna processing GO:0006364 35 0.062
ncrna metabolic process GO:0034660 108 0.062
ribonucleotide catabolic process GO:0009261 405 0.061
regulation of protein kinase activity GO:0045859 289 0.060
rna splicing via transesterification reactions GO:0000375 90 0.060
response to bacterium GO:0009617 144 0.058
response to oxidative stress GO:0006979 121 0.057
glycosyl compound catabolic process GO:1901658 413 0.057
oogenesis GO:0048477 2 0.057
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.056
mitochondrion organization GO:0007005 156 0.056
regulation of mrna processing GO:0050684 48 0.056
regulation of cellular response to stress GO:0080135 244 0.056
ribonucleoside monophosphate catabolic process GO:0009158 158 0.055
regulation of cell cycle GO:0051726 393 0.055
Fly
mrna 3 end processing GO:0031124 24 0.055
peptidyl tyrosine phosphorylation GO:0018108 170 0.055
regulation of myeloid cell differentiation GO:0045637 81 0.055
peptidyl tyrosine modification GO:0018212 170 0.053
ribosome biogenesis GO:0042254 48 0.052
reactive oxygen species metabolic process GO:0072593 75 0.051
positive regulation of cell proliferation GO:0008284 301 0.050
epithelium development GO:0060429 227 0.049
exit from mitosis GO:0010458 10 0.049
Worm
regulation of dna metabolic process GO:0051052 153 0.048
mitotic cell cycle process GO:1903047 286 0.047
Worm Fly
response to external biotic stimulus GO:0043207 261 0.046
neuroblast proliferation GO:0007405 4 0.046
negative regulation of wnt signaling pathway GO:0030178 69 0.046
cellular response to endogenous stimulus GO:0071495 336 0.046
mrna splicing via spliceosome GO:0000398 89 0.046
purine containing compound catabolic process GO:0072523 411 0.046
negative regulation of cell proliferation GO:0008285 228 0.044
negative regulation of myeloid cell differentiation GO:0045638 42 0.043
negative regulation of phosphate metabolic process GO:0045936 267 0.043
circulatory system development GO:0072359 262 0.043
determination of adult lifespan GO:0008340 2 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
positive regulation of phosphorylation GO:0042327 394 0.038
blastoderm segmentation GO:0007350 2 0.037
embryonic placenta development GO:0001892 1 0.037
response to light stimulus GO:0009416 87 0.037
otic vesicle development GO:0071599 1 0.036
regulation of reactive oxygen species metabolic process GO:2000377 41 0.036
protein import GO:0017038 130 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
positive regulation of transcription from rna polymerase i promoter GO:0045943 6 0.035
regulation of histone methylation GO:0031060 16 0.035
regulation of macroautophagy GO:0016241 19 0.035
regulation of transcription from rna polymerase i promoter GO:0006356 10 0.034
cell cycle arrest GO:0007050 71 0.034
histone methylation GO:0016571 60 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.033
viral life cycle GO:0019058 132 0.033
myeloid cell homeostasis GO:0002262 34 0.033
positive regulation of response to extracellular stimulus GO:0032106 14 0.033
regulation of cell activation GO:0050865 125 0.033
osteoblast differentiation GO:0001649 92 0.032
purine nucleoside monophosphate metabolic process GO:0009126 186 0.032
macromolecular complex disassembly GO:0032984 60 0.032
isotype switching GO:0045190 3 0.031
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.031
histone h3 acetylation GO:0043966 45 0.030
dna replication independent nucleosome assembly GO:0006336 27 0.030
protein localization to organelle GO:0033365 280 0.029
nucleoside phosphate catabolic process GO:1901292 412 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
cardiovascular system development GO:0072358 262 0.029
nucleosome organization GO:0034728 66 0.029
base excision repair GO:0006284 21 0.028
negative regulation of hydrolase activity GO:0051346 182 0.028
mapk cascade GO:0000165 288 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
regulation of neural precursor cell proliferation GO:2000177 4 0.028
regulation of transcription by glucose GO:0046015 4 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
positive regulation of mrna metabolic process GO:1903313 19 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
negative regulation of dna templated transcription elongation GO:0032785 6 0.028
response to uv GO:0009411 73 0.027
negative regulation of chromosome organization GO:2001251 48 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
regulation of protein complex assembly GO:0043254 147 0.027
nucleocytoplasmic transport GO:0006913 176 0.027
negative regulation of protein modification process GO:0031400 200 0.027
regulation of immunoglobulin production GO:0002637 4 0.027
regeneration GO:0031099 4 0.027
regulation of cell motility GO:2000145 299 0.027
regulation of heart growth GO:0060420 4 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.026
regulation of cell adhesion GO:0030155 166 0.026
leukocyte mediated immunity GO:0002443 59 0.026
response to hormone GO:0009725 175 0.026
cellular protein catabolic process GO:0044257 261 0.026
intracellular protein transport GO:0006886 270 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
dna recombination GO:0006310 77 0.025
enzyme linked receptor protein signaling pathway GO:0007167 303 0.025
lung alveolus development GO:0048286 4 0.025
apoptotic signaling pathway GO:0097190 268 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
cellular component disassembly GO:0022411 92 0.024
atp catabolic process GO:0006200 157 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
rhythmic behavior GO:0007622 2 0.024
endocytosis GO:0006897 159 0.024
positive regulation of protein complex assembly GO:0031334 86 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
positive regulation of catabolic process GO:0009896 310 0.024
gtp catabolic process GO:0006184 237 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
regulation of chromosome organization GO:0033044 103 0.023
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.023
blastocyst development GO:0001824 3 0.023
establishment of rna localization GO:0051236 39 0.023
regulation of wnt signaling pathway GO:0030111 123 0.022
regulation of response to nutrient levels GO:0032107 22 0.022
negative regulation of developmental process GO:0051093 247 0.022
regulation of cellular component movement GO:0051270 334 0.022
regulation of phosphatase activity GO:0010921 81 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.022
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.022
vesicle mediated transport GO:0016192 371 0.021
dna templated transcription initiation GO:0006352 35 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
7 methylguanosine rna capping GO:0009452 9 0.021
locomotory behavior GO:0007626 1 0.021
cell development GO:0048468 328 0.020
regulation of protein tyrosine kinase activity GO:0061097 36 0.020
protein complex disassembly GO:0043241 52 0.020
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
cell morphogenesis GO:0000902 296 0.020
regulation of intracellular transport GO:0032386 195 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
Fly
regulation of map kinase activity GO:0043405 108 0.020
cellular component morphogenesis GO:0032989 314 0.020
response to lipid GO:0033993 206 0.020
compound eye development GO:0048749 1 0.019
immune response GO:0006955 307 0.019
protein methylation GO:0006479 74 0.019
Worm
growth GO:0040007 202 0.019
negative regulation of transferase activity GO:0051348 124 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
erythrocyte homeostasis GO:0034101 31 0.019
regulation of locomotion GO:0040012 329 0.019
cell fate determination GO:0001709 3 0.019
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.019
regulation of isotype switching GO:0045191 2 0.019
oxidative stress induced premature senescence GO:0090403 3 0.019
regulation of growth GO:0040008 165 0.019
negative regulation of cell cycle GO:0045786 193 0.019
Fly
positive regulation of hormone biosynthetic process GO:0046886 4 0.019
regulation of cell development GO:0060284 161 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
defense response GO:0006952 315 0.018
dna conformation change GO:0071103 113 0.018
protein dna complex assembly GO:0065004 64 0.018
nucleobase containing compound transport GO:0015931 51 0.018
ras protein signal transduction GO:0007265 73 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
positive regulation of neural precursor cell proliferation GO:2000179 2 0.018
developmental growth GO:0048589 48 0.018
regulation of muscle cell differentiation GO:0051147 31 0.018
reproductive process GO:0022414 106 0.018
positive regulation of cell development GO:0010720 92 0.018
regulation of immune response GO:0050776 201 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
protein targeting GO:0006605 187 0.018
actin cytoskeleton organization GO:0030036 207 0.018
chordate embryonic development GO:0043009 34 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.018
cell type specific apoptotic process GO:0097285 125 0.017
lipid metabolic process GO:0006629 381 0.017
mrna transport GO:0051028 30 0.017
protein oligomerization GO:0051259 173 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
regulation of protein processing GO:0070613 150 0.017
embryo development GO:0009790 123 0.017
Worm
mrna polyadenylation GO:0006378 12 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
protein acetylation GO:0006473 116 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
rna interference GO:0016246 4 0.017
immune effector process GO:0002252 159 0.017
cell cycle g1 s phase transition GO:0044843 80 0.017
circadian behavior GO:0048512 2 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
neuromuscular junction development GO:0007528 3 0.017
positive regulation of gtpase activity GO:0043547 166 0.016
microtubule based process GO:0007017 210 0.016
Worm
oocyte development GO:0048599 1 0.016
neural tube formation GO:0001841 3 0.016
methylation dependent chromatin silencing GO:0006346 3 0.016
somatic stem cell maintenance GO:0035019 4 0.016
tissue regeneration GO:0042246 3 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
regulation of cardiac muscle cell proliferation GO:0060043 4 0.016
methylation GO:0032259 106 0.016
Worm
internal peptidyl lysine acetylation GO:0018393 97 0.016
forebrain generation of neurons GO:0021872 3 0.016
nervous system development GO:0007399 293 0.016
epidermis morphogenesis GO:0048730 3 0.016
negative regulation of immune system process GO:0002683 136 0.016
adaptive immune response GO:0002250 49 0.016
response to organonitrogen compound GO:0010243 156 0.016
regulation of neurogenesis GO:0050767 82 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
forebrain neuron differentiation GO:0021879 3 0.015
histone acetylation GO:0016573 93 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
mating GO:0007618 1 0.015
response to cytokine GO:0034097 232 0.015
positive regulation of macroautophagy GO:0016239 12 0.015
neuron death GO:0070997 65 0.015
negative regulation of chromatin modification GO:1903309 21 0.015
protein catabolic process GO:0030163 325 0.015
regulation of neuron differentiation GO:0045664 70 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.015
regulation of response to extracellular stimulus GO:0032104 22 0.015
leukocyte activation involved in immune response GO:0002366 30 0.015
protein polyubiquitination GO:0000209 110 0.015
single organism membrane organization GO:0044802 268 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
carbohydrate metabolic process GO:0005975 207 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
regulation of lipid metabolic process GO:0019216 96 0.014
regulation of neuroblast proliferation GO:1902692 3 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
reproduction GO:0000003 63 0.014
Worm
membrane organization GO:0061024 292 0.014
receptor mediated endocytosis GO:0006898 84 0.014
regionalization GO:0003002 29 0.014
single organism reproductive process GO:0044702 98 0.014
response to axon injury GO:0048678 1 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
regulation of lymphocyte mediated immunity GO:0002706 33 0.014
metal ion transport GO:0030001 272 0.014
nuclear transport GO:0051169 179 0.014
chemotaxis GO:0006935 157 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
regulation of mapk cascade GO:0043408 262 0.014
nuclear import GO:0051170 106 0.014
regulation of secretion GO:0051046 194 0.014
t cell differentiation in thymus GO:0033077 4 0.014
activation of protein kinase activity GO:0032147 90 0.014
innate immune response GO:0045087 178 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
response to oxygen containing compound GO:1901700 369 0.014
muscle structure development GO:0061061 98 0.014
dna replication GO:0006260 116 0.014
heart formation GO:0060914 2 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
regulation of cell growth GO:0001558 135 0.013
chromatin assembly GO:0031497 61 0.013
lymphocyte activation GO:0046649 133 0.013
apoptotic mitochondrial changes GO:0008637 57 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
protein acylation GO:0043543 138 0.013
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.013
gtp metabolic process GO:0046039 239 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of stress activated mapk cascade GO:0032872 84 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
stress activated mapk cascade GO:0051403 93 0.013
regulation of b cell activation GO:0050864 24 0.013
mrna export from nucleus GO:0006406 29 0.013
taxis GO:0042330 157 0.013
organ formation GO:0048645 3 0.013
cell activation GO:0001775 213 0.013
regulation of immune effector process GO:0002697 91 0.013
oocyte differentiation GO:0009994 2 0.013
positive regulation of neurogenesis GO:0050769 49 0.013
glycerolipid metabolic process GO:0046486 107 0.013
regulation of lipid biosynthetic process GO:0046890 47 0.013
double strand break repair GO:0006302 101 0.013
response to inorganic substance GO:0010035 127 0.012
response to hypoxia GO:0001666 96 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
cell growth GO:0016049 160 0.012
negative regulation of dna metabolic process GO:0051053 57 0.012
b cell mediated immunity GO:0019724 10 0.012
histone h2b ubiquitination GO:0033523 8 0.012
establishment of tissue polarity GO:0007164 3 0.012
homeostasis of number of cells GO:0048872 40 0.012
response to nitrogen compound GO:1901698 184 0.012
neuron migration GO:0001764 11 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
embryonic hemopoiesis GO:0035162 4 0.012
regulation of dephosphorylation GO:0035303 96 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.012
gene silencing by mirna GO:0035195 23 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
positive regulation of cell death GO:0010942 263 0.012
cell part morphogenesis GO:0032990 137 0.012
regulation of gtpase activity GO:0043087 180 0.012
cellular lipid metabolic process GO:0044255 303 0.012
single organism nuclear import GO:1902593 104 0.012
negative regulation of organelle organization GO:0010639 126 0.012
interspecies interaction between organisms GO:0044419 156 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
spermatid development GO:0007286 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
cell projection organization GO:0030030 252 0.012
muscle system process GO:0003012 81 0.012
dna templated transcription termination GO:0006353 3 0.011
neuron differentiation GO:0030182 138 0.011
limbic system development GO:0021761 3 0.011
spermatid differentiation GO:0048515 4 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
cellular response to peptide hormone stimulus GO:0071375 56 0.011
ectoderm development GO:0007398 3 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
single organism cellular localization GO:1902580 332 0.011
production of molecular mediator of immune response GO:0002440 37 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
biological adhesion GO:0022610 331 0.011
myoblast fusion GO:0007520 1 0.011
response to peptide GO:1901652 65 0.011
leukocyte activation GO:0045321 164 0.011
jnk cascade GO:0007254 80 0.011
negative regulation of cell death GO:0060548 345 0.011
purine ribonucleotide biosynthetic process GO:0009152 79 0.011
organ induction GO:0001759 4 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
secretion GO:0046903 254 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
regulation of leukocyte activation GO:0002694 115 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
memory GO:0007613 3 0.011

POLR2A disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.742
disease of cellular proliferation DOID:14566 174 0.742
organ system cancer DOID:0050686 164 0.684
sensory system disease DOID:0050155 203 0.354
eye and adnexa disease DOID:1492 150 0.354
nervous system disease DOID:863 431 0.354
retinal disease DOID:5679 118 0.183
eye disease DOID:5614 149 0.183
retinal degeneration DOID:8466 89 0.119
macular degeneration DOID:4448 20 0.119
degeneration of macula and posterior pole DOID:2007 17 0.079
age related macular degeneration DOID:10871 17 0.079
respiratory system cancer DOID:0050615 16 0.063
gastrointestinal system cancer DOID:3119 52 0.044
musculoskeletal system disease DOID:17 223 0.025
disease of metabolism DOID:0014667 295 0.015
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.013
central nervous system disease DOID:331 186 0.013