Homo sapiens

273 known processes

POU5F1

POU class 5 homeobox 1

(Aliases: OTF-3,OCT4,OCT3,OTF3,MGC22487,Oct-3,Oct-4,OTF4)

POU5F1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extraocular skeletal muscle development GO:0002074 1 1.000
menstrual cycle phase GO:0022601 2 1.000
menstruation GO:0042703 1 1.000
hard palate development GO:0060022 1 1.000
cardiac cell fate determination GO:0060913 3 1.000
neural crest cell development GO:0014032 3 0.999
enteric nervous system development GO:0048484 1 0.999
cranial nerve development GO:0021545 4 0.996
trophectodermal cell differentiation GO:0001829 3 0.990
Mouse
soft palate development GO:0060023 3 0.981
endochondral bone morphogenesis GO:0060350 3 0.981
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.974
nerve development GO:0021675 4 0.973
blastocyst formation GO:0001825 3 0.964
Mouse
tongue development GO:0043586 1 0.962
nucleosome assembly GO:0006334 50 0.960
positive regulation of osteoblast differentiation GO:0045669 23 0.941
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.938
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.934
lymphangiogenesis GO:0001946 7 0.932
forebrain generation of neurons GO:0021872 3 0.929
endocrine system development GO:0035270 26 0.926
peripheral nervous system development GO:0007422 2 0.920
endothelial cell migration GO:0043542 86 0.918
ameboidal type cell migration GO:0001667 135 0.915
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.911
Mouse
equilibrioception GO:0050957 6 0.906
regulation of stem cell differentiation GO:2000736 56 0.897
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.889
cellular ketone metabolic process GO:0042180 80 0.884
cell fate determination GO:0001709 3 0.874
positive regulation of peptidase activity GO:0010952 88 0.868
neural crest cell migration GO:0001755 2 0.860
regulation of endopeptidase activity GO:0052548 170 0.852
pharynx development GO:0060465 1 0.847
mesenchymal cell development GO:0014031 50 0.844
regulation of peptidase activity GO:0052547 180 0.837
positive regulation of male gonad development GO:2000020 3 0.827
somatic stem cell maintenance GO:0035019 4 0.817
positive regulation of endopeptidase activity GO:0010950 84 0.815
epithelial cell migration GO:0010631 119 0.814
cellular amino acid metabolic process GO:0006520 116 0.809
regulation of cell migration GO:0030334 289 0.803
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.797
chromatin assembly or disassembly GO:0006333 78 0.796
cellular amine metabolic process GO:0044106 41 0.793
regulation of cell motility GO:2000145 299 0.789
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.784
negative regulation of stem cell differentiation GO:2000737 22 0.773
blastocyst development GO:0001824 3 0.765
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.765
pancreas development GO:0031016 19 0.760
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.752
thymus development GO:0048538 3 0.748
male genitalia development GO:0030539 1 0.745
regulation of locomotion GO:0040012 329 0.744
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.739
positive regulation of proteolysis GO:0045862 142 0.734
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.712
mesenchymal cell differentiation GO:0048762 52 0.706
enzyme linked receptor protein signaling pathway GO:0007167 303 0.702
negative regulation of protein metabolic process GO:0051248 391 0.702
digestive system development GO:0055123 75 0.700
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.690
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.687
Human
forebrain neuron differentiation GO:0021879 3 0.683
negative regulation of glial cell proliferation GO:0060253 2 0.682
protein ubiquitination GO:0016567 314 0.678
autonomic nervous system development GO:0048483 1 0.667
negative regulation of gliogenesis GO:0014014 3 0.665
negative regulation of apoptotic process GO:0043066 316 0.660
canonical wnt signaling pathway GO:0060070 116 0.656
regulation of epithelial to mesenchymal transition GO:0010717 37 0.638
regulation of cellular amino acid metabolic process GO:0006521 6 0.638
regulation of body fluid levels GO:0050878 99 0.638
lymph vessel development GO:0001945 9 0.628
chromatin assembly GO:0031497 61 0.622
cardiac cell fate commitment GO:0060911 7 0.619
embryonic placenta development GO:0001892 1 0.612
thyroid gland development GO:0030878 5 0.609
response to lipid GO:0033993 206 0.598
Mouse
stem cell development GO:0048864 69 0.595
positive regulation of mesenchymal stem cell differentiation GO:2000741 4 0.586
anatomical structure formation involved in morphogenesis GO:0048646 284 0.573
negative regulation of transport GO:0051051 176 0.569
Mouse
cell development GO:0048468 328 0.569
cellular macromolecule catabolic process GO:0044265 380 0.551
epithelial cell differentiation GO:0030855 141 0.549
positive regulation of cellular amine metabolic process GO:0033240 7 0.546
female gonad development GO:0008585 10 0.540
response to wounding GO:0009611 168 0.527
bone morphogenesis GO:0060349 10 0.522
negative regulation of multicellular organismal process GO:0051241 317 0.520
neuron fate commitment GO:0048663 2 0.511
notch signaling pathway GO:0007219 31 0.511
neuroblast proliferation GO:0007405 4 0.504
endoderm formation GO:0001706 33 0.502
regulation of protein transport GO:0051223 213 0.498
osteoblast differentiation GO:0001649 92 0.497
regulation of cell cycle GO:0051726 393 0.496
nervous system development GO:0007399 293 0.495
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.494
stem cell differentiation GO:0048863 93 0.492
positive regulation of neural precursor cell proliferation GO:2000179 2 0.490
protein acylation GO:0043543 138 0.490
negative regulation of cell cycle GO:0045786 193 0.489
negative regulation of protein modification process GO:0031400 200 0.488
mesenchyme development GO:0060485 59 0.487
positive regulation of developmental process GO:0051094 314 0.473
response to abiotic stimulus GO:0009628 336 0.470
cytoplasmic transport GO:0016482 379 0.468
angiogenesis GO:0001525 147 0.468
chromatin organization GO:0006325 351 0.456
regulation of proteolysis GO:0030162 293 0.444
regeneration GO:0031099 4 0.442
positive regulation of cell cycle GO:0045787 140 0.441
positive regulation of hydrolase activity GO:0051345 331 0.441
chromatin modification GO:0016568 298 0.438
regulation of blood coagulation GO:0030193 42 0.433
positive regulation of epithelial cell migration GO:0010634 55 0.433
hemostasis GO:0007599 76 0.429
regulation of cell cycle arrest GO:0071156 36 0.425
positive regulation of programmed cell death GO:0043068 249 0.417
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.412
regulation of epithelial cell migration GO:0010632 93 0.412
negative regulation of mitotic cell cycle GO:0045930 102 0.411
positive regulation of apoptotic process GO:0043065 246 0.410
signal transduction in response to dna damage GO:0042770 57 0.404
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.395
negative regulation of cellular protein metabolic process GO:0032269 353 0.391
cellular response to endogenous stimulus GO:0071495 336 0.388
cardiocyte differentiation GO:0035051 23 0.386
coagulation GO:0050817 78 0.385
lymph vessel morphogenesis GO:0036303 7 0.376
blood vessel development GO:0001568 172 0.373
protein acetylation GO:0006473 116 0.370
positive regulation of cell death GO:0010942 263 0.368
ion transmembrane transport GO:0034220 338 0.361
brain morphogenesis GO:0048854 1 0.361
regulation of glial cell proliferation GO:0060251 4 0.355
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.351
regulation of cellular ketone metabolic process GO:0010565 50 0.346
regulation of cysteine type endopeptidase activity GO:2000116 127 0.346
neuron differentiation GO:0030182 138 0.344
positive regulation of stem cell differentiation GO:2000738 29 0.343
mitotic cell cycle GO:0000278 326 0.342
blood coagulation GO:0007596 76 0.337
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.334
epithelium development GO:0060429 227 0.330
gliogenesis GO:0042063 21 0.329
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.329
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.327
negative regulation of cellular component organization GO:0051129 235 0.327
melanocyte differentiation GO:0030318 2 0.325
negative regulation of developmental process GO:0051093 247 0.325
bone development GO:0060348 26 0.319
response to estrogen GO:0043627 47 0.318
cell cycle checkpoint GO:0000075 117 0.317
endoderm development GO:0007492 33 0.316
gastrulation GO:0007369 51 0.315
wound healing GO:0042060 115 0.315
second messenger mediated signaling GO:0019932 78 0.312
male sex differentiation GO:0046661 25 0.311
immune system development GO:0002520 195 0.310
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.306
negative regulation of cell differentiation GO:0045596 171 0.305
protein modification by small protein conjugation GO:0032446 342 0.305
cell cycle arrest GO:0007050 71 0.300
regulation of response to external stimulus GO:0032101 222 0.300
positive regulation of locomotion GO:0040017 186 0.295
tissue migration GO:0090130 119 0.290
negative regulation of cell cycle process GO:0010948 121 0.290
glial cell development GO:0021782 7 0.285
regulation of response to wounding GO:1903034 101 0.285
regulation of coagulation GO:0050818 44 0.282
epithelium migration GO:0090132 119 0.281
nucleosome organization GO:0034728 66 0.280
nucleocytoplasmic transport GO:0006913 176 0.279
cellular response to growth factor stimulus GO:0071363 197 0.279
vasculature development GO:0001944 181 0.278
apoptotic nuclear changes GO:0030262 13 0.272
ovulation cycle process GO:0022602 9 0.272
wnt signaling pathway GO:0016055 156 0.272
skeletal system development GO:0001501 79 0.270
regulation of hemostasis GO:1900046 42 0.269
negative regulation of epithelial cell proliferation GO:0050680 48 0.261
regulation of neuroblast proliferation GO:1902692 3 0.258
positive regulation of epithelial cell proliferation GO:0050679 65 0.254
neural crest cell differentiation GO:0014033 5 0.250
endocrine pancreas development GO:0031018 11 0.250
negative regulation of cell death GO:0060548 345 0.249
tube development GO:0035295 125 0.249
cardiovascular system development GO:0072358 262 0.246
positive regulation of cell motility GO:2000147 177 0.243
ectodermal placode formation GO:0060788 1 0.241
regulation of cell differentiation GO:0045595 393 0.240
ovulation cycle GO:0042698 9 0.236
response to organic cyclic compound GO:0014070 204 0.233
regulation of neural precursor cell proliferation GO:2000177 4 0.231
dna catabolic process endonucleolytic GO:0000737 37 0.227
taxis GO:0042330 157 0.222
cellular response to nitrogen compound GO:1901699 144 0.219
cellular component disassembly GO:0022411 92 0.218
alcohol metabolic process GO:0006066 114 0.216
regulation of wound healing GO:0061041 56 0.216
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 5 0.213
dna catabolic process GO:0006308 49 0.213
cell morphogenesis GO:0000902 296 0.213
response to estradiol GO:0032355 23 0.213
regulation of mapk cascade GO:0043408 262 0.211
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.205
embryo development GO:0009790 123 0.204
regulation of epithelial cell proliferation GO:0050678 113 0.204
blood vessel morphogenesis GO:0048514 162 0.203
lung morphogenesis GO:0060425 6 0.203
regulation of intracellular protein transport GO:0033157 123 0.203
response to steroid hormone GO:0048545 80 0.203
mitotic g1 dna damage checkpoint GO:0031571 17 0.199
regulation of canonical wnt signaling pathway GO:0060828 88 0.198
n terminal peptidyl lysine acetylation GO:0018076 4 0.198
detection of stimulus GO:0051606 85 0.196
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.196
hematopoietic or lymphoid organ development GO:0048534 186 0.195
positive regulation of chondrocyte differentiation GO:0032332 4 0.195
cellular potassium ion transport GO:0071804 60 0.194
single organism cellular localization GO:1902580 332 0.193
lipid biosynthetic process GO:0008610 177 0.190
positive regulation of mitotic cell cycle GO:0045931 60 0.188
morphogenesis of a branching structure GO:0001763 21 0.188
regulation of cytoplasmic transport GO:1903649 149 0.187
positive regulation of reproductive process GO:2000243 9 0.186
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.185
regulation of cell growth GO:0001558 135 0.183
developmental pigmentation GO:0048066 12 0.181
lymphocyte activation GO:0046649 133 0.181
positive regulation of cell differentiation GO:0045597 211 0.180
cellular component morphogenesis GO:0032989 314 0.175
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.175
circulatory system development GO:0072359 262 0.174
generation of neurons GO:0048699 152 0.174
epithelial to mesenchymal transition GO:0001837 48 0.174
detection of stimulus involved in sensory perception GO:0050906 43 0.174
lipid metabolic process GO:0006629 381 0.172
positive regulation of cellular component movement GO:0051272 181 0.171
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.169
response to mechanical stimulus GO:0009612 51 0.169
blood vessel endothelial cell migration GO:0043534 42 0.168
response to peptide GO:1901652 65 0.167
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.166
response to transforming growth factor beta GO:0071559 94 0.166
positive regulation of n terminal peptidyl lysine acetylation GO:2000761 1 0.166
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.165
cell projection organization GO:0030030 252 0.163
intracellular receptor signaling pathway GO:0030522 104 0.163
Human
mitotic cell cycle checkpoint GO:0007093 68 0.161
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.160
regulation of mitotic cell cycle GO:0007346 189 0.159
ovarian follicle development GO:0001541 5 0.159
dna damage response detection of dna damage GO:0042769 3 0.158
regulation of cell cycle phase transition GO:1901987 126 0.158
amine metabolic process GO:0009308 44 0.156
pigmentation GO:0043473 22 0.156
palate development GO:0060021 13 0.156
response to hormone GO:0009725 175 0.153
ossification GO:0001503 121 0.151
skeletal system morphogenesis GO:0048705 24 0.150
negative regulation of leukocyte activation GO:0002695 26 0.148
execution phase of apoptosis GO:0097194 32 0.147
regulation of protein stability GO:0031647 87 0.146
mononuclear cell proliferation GO:0032943 71 0.145
chondrocyte differentiation involved in endochondral bone morphogenesis GO:0003413 1 0.143
cellular response to lipid GO:0071396 127 0.143
negative regulation of cell development GO:0010721 48 0.143
mrna transcription from rna polymerase ii promoter GO:0042789 6 0.142
Mouse
establishment of protein localization to organelle GO:0072594 172 0.141
posttranscriptional regulation of gene expression GO:0010608 213 0.141
lens morphogenesis in camera type eye GO:0002089 2 0.140
neurogenesis GO:0022008 169 0.139
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.139
tissue regeneration GO:0042246 3 0.138
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.137
regulation of translation GO:0006417 89 0.137
cell cell signaling GO:0007267 155 0.136
connective tissue development GO:0061448 39 0.135
heart development GO:0007507 95 0.132
prostate gland development GO:0030850 3 0.130
negative regulation of cellular component movement GO:0051271 106 0.129
cell morphogenesis involved in differentiation GO:0000904 144 0.126
pituitary gland development GO:0021983 2 0.123
skeletal muscle tissue development GO:0007519 24 0.121
stem cell maintenance GO:0019827 19 0.120
protein localization to organelle GO:0033365 280 0.120
positive regulation of mapk cascade GO:0043410 190 0.119
cellular response to peptide GO:1901653 59 0.118
regulation of cellular response to growth factor stimulus GO:0090287 76 0.115
multicellular organismal aging GO:0010259 3 0.114
endothelial cell development GO:0001885 18 0.114
reproductive process GO:0022414 106 0.114
multi organism cellular process GO:0044764 156 0.113
Human
male gonad development GO:0008584 23 0.113
interspecies interaction between organisms GO:0044419 156 0.112
Human
regulation of cell morphogenesis GO:0022604 153 0.112
hair cycle process GO:0022405 12 0.111
cerebral cortex development GO:0021987 10 0.111
ectodermal placode development GO:0071696 1 0.110
mitotic g1 s transition checkpoint GO:0044819 17 0.110
cell fate specification GO:0001708 8 0.109
cellular response to cytokine stimulus GO:0071345 181 0.109
digestive tract development GO:0048565 75 0.109
response to alcohol GO:0097305 64 0.108
regulation of mononuclear cell proliferation GO:0032944 65 0.105
cellular response to acid chemical GO:0071229 44 0.104
epithelial cell development GO:0002064 34 0.103
dna conformation change GO:0071103 113 0.103
branching morphogenesis of an epithelial tube GO:0048754 19 0.101
positive regulation of cell migration GO:0030335 172 0.101
negative regulation of immune system process GO:0002683 136 0.101
dna damage checkpoint GO:0000077 68 0.099
lymphocyte proliferation GO:0046651 70 0.099
regulation of endosome size GO:0051036 3 0.098
cellular response to insulin stimulus GO:0032869 41 0.098
cellular response to hormone stimulus GO:0032870 125 0.098
regulation of ketone biosynthetic process GO:0010566 7 0.097
striated muscle tissue development GO:0014706 59 0.096
cellular response to organonitrogen compound GO:0071417 124 0.096
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.095
cellular response to peptide hormone stimulus GO:0071375 56 0.094
viral process GO:0016032 146 0.094
Human
cell projection morphogenesis GO:0048858 129 0.092
mitotic cell cycle phase transition GO:0044772 162 0.090
organ morphogenesis GO:0009887 147 0.089
development of primary male sexual characteristics GO:0046546 23 0.089
regulation of protein localization GO:0032880 296 0.088
glial cell differentiation GO:0010001 11 0.087
sex determination GO:0007530 3 0.087
epithelial tube morphogenesis GO:0060562 38 0.086
protein dna complex subunit organization GO:0071824 80 0.086
anterior posterior axis specification GO:0009948 2 0.086
regulation of mitotic cell cycle phase transition GO:1901990 118 0.086
intracellular protein transport GO:0006886 270 0.085
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.084
steroid biosynthetic process GO:0006694 46 0.084
regulation of n terminal peptidyl lysine acetylation GO:2000759 1 0.083
regulation of lymphocyte proliferation GO:0050670 64 0.083
mitotic dna integrity checkpoint GO:0044774 30 0.082
cellular response to abiotic stimulus GO:0071214 117 0.082
monocarboxylic acid metabolic process GO:0032787 185 0.082
cell cycle phase transition GO:0044770 173 0.082
negative regulation of programmed cell death GO:0043069 321 0.081
negative regulation of cellular amine metabolic process GO:0033239 3 0.081
ectodermal placode morphogenesis GO:0071697 1 0.081
dolichol biosynthetic process GO:0019408 1 0.081
sodium ion transport GO:0006814 61 0.081
sensory perception GO:0007600 103 0.081
post embryonic development GO:0009791 2 0.081
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.080
cell cell signaling involved in cell fate commitment GO:0045168 5 0.080
neuroepithelial cell differentiation GO:0060563 5 0.080
negative regulation of ossification GO:0030279 21 0.080
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.079
negative regulation of protein ubiquitination GO:0031397 35 0.078
apoptotic dna fragmentation GO:0006309 6 0.078
insulin receptor signaling pathway GO:0008286 23 0.078
negative regulation of catalytic activity GO:0043086 335 0.078
response to cytokine GO:0034097 232 0.078
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.077
positive regulation of cell proliferation GO:0008284 301 0.076
Human
regulation of isoprenoid metabolic process GO:0019747 1 0.076
cell growth GO:0016049 160 0.075
central nervous system development GO:0007417 123 0.075
tissue morphogenesis GO:0048729 96 0.074
Mouse
response to peptide hormone GO:0043434 61 0.073
endocytosis GO:0006897 159 0.072
regulation of cellular component movement GO:0051270 334 0.072
negative regulation of phosphorylation GO:0042326 174 0.072
trna processing GO:0008033 23 0.070
response to organonitrogen compound GO:0010243 156 0.070
regulation of protein acetylation GO:1901983 25 0.070
positive regulation of notch signaling pathway GO:0045747 6 0.070
maintenance of location GO:0051235 112 0.069
positive regulation of catabolic process GO:0009896 310 0.068
negative regulation of cytoplasmic transport GO:1903650 46 0.068
peptidyl lysine acetylation GO:0018394 101 0.068
positive regulation of translation GO:0045727 35 0.068
cellular protein catabolic process GO:0044257 261 0.067
positive regulation of ossification GO:0045778 32 0.067
regulation of anatomical structure morphogenesis GO:0022603 286 0.067
neuron development GO:0048666 113 0.066
development of primary female sexual characteristics GO:0046545 10 0.066
modification dependent protein catabolic process GO:0019941 209 0.065
regulation of multi organism process GO:0043900 157 0.065
Human
regulation of chondrocyte differentiation GO:0032330 9 0.064
sensory perception of mechanical stimulus GO:0050954 37 0.064
odontogenesis GO:0042476 25 0.064
negative regulation of transferase activity GO:0051348 124 0.063
signal transduction by phosphorylation GO:0023014 297 0.062
Human
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.062
pigment cell differentiation GO:0050931 11 0.062
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.061
skeletal muscle organ development GO:0060538 26 0.060
sodium ion transmembrane transport GO:0035725 59 0.060
biological phase GO:0044848 5 0.060
eye development GO:0001654 42 0.060
regulation of transferase activity GO:0051338 355 0.060
leukocyte proliferation GO:0070661 74 0.060
chemotaxis GO:0006935 157 0.059
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.059
Human
reproductive structure development GO:0048608 55 0.059
cellular lipid metabolic process GO:0044255 303 0.059
regulation of actin cytoskeleton organization GO:0032956 116 0.059
inorganic ion transmembrane transport GO:0098660 231 0.059
regulation of lymphocyte activation GO:0051249 103 0.058
protein autoubiquitination GO:0051865 37 0.058
response to insulin GO:0032868 45 0.057
regulation of growth GO:0040008 165 0.057
endodermal cell fate commitment GO:0001711 4 0.057
response to interleukin 1 GO:0070555 47 0.057
molting cycle process GO:0022404 12 0.057
female sex differentiation GO:0046660 12 0.056
negative regulation of intracellular transport GO:0032387 60 0.056
cation transmembrane transport GO:0098655 238 0.056
regulation of cell development GO:0060284 161 0.055
mitotic cell cycle process GO:1903047 286 0.055
muscle structure development GO:0061061 98 0.055
endothelial cell differentiation GO:0045446 26 0.053
actin filament based process GO:0030029 224 0.053
negative regulation of protein phosphorylation GO:0001933 140 0.053
response to oxygen containing compound GO:1901700 369 0.052
Mouse
positive regulation of transport GO:0051050 336 0.052
ubiquitin dependent protein catabolic process GO:0006511 206 0.052
protein catabolic process GO:0030163 325 0.052
dna packaging GO:0006323 77 0.052
fatty acid metabolic process GO:0006631 115 0.052
regulation of protein ubiquitination GO:0031396 95 0.051
cofactor metabolic process GO:0051186 87 0.050
receptor internalization GO:0031623 43 0.050
cell part morphogenesis GO:0032990 137 0.049
regulation of anatomical structure size GO:0090066 101 0.049
mitotic dna damage checkpoint GO:0044773 28 0.048
camera type eye development GO:0043010 25 0.048
inorganic cation transmembrane transport GO:0098662 194 0.048
regulation of cell cycle process GO:0010564 266 0.048
gonad development GO:0008406 34 0.048
cartilage development GO:0051216 31 0.047
regulation of actin filament based process GO:0032970 141 0.047
positive regulation of cellular catabolic process GO:0031331 284 0.047
endodermal cell fate specification GO:0001714 4 0.047
positive regulation of neuroblast proliferation GO:0002052 2 0.047
mesenchymal stem cell differentiation GO:0072497 8 0.047
cell cycle g1 s phase transition GO:0044843 80 0.046
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.046
pigment biosynthetic process GO:0046148 10 0.045
forebrain development GO:0030900 26 0.045
modification dependent macromolecule catabolic process GO:0043632 212 0.045
epithelial cell proliferation GO:0050673 128 0.045
developmental induction GO:0031128 5 0.045
regulation of establishment of protein localization GO:0070201 242 0.045
negative regulation of growth GO:0045926 97 0.045
reproductive system development GO:0061458 56 0.044
cellular response to oxygen containing compound GO:1901701 276 0.044
morphogenesis of an epithelium GO:0002009 60 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.044
gland development GO:0048732 48 0.044
rna processing GO:0006396 255 0.043
blastoderm segmentation GO:0007350 2 0.043
cell activation GO:0001775 213 0.043
response to nitrogen compound GO:1901698 184 0.043
ear morphogenesis GO:0042471 7 0.042
growth GO:0040007 202 0.042
Mouse
odontogenesis of dentin containing tooth GO:0042475 10 0.042
positive regulation of lipid metabolic process GO:0045834 50 0.042
peptidyl lysine modification GO:0018205 144 0.042
chromatin remodeling GO:0006338 55 0.042
nuclear export GO:0051168 69 0.042
mitochondrion organization GO:0007005 156 0.041
hindbrain development GO:0030902 3 0.041
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.041
endosomal transport GO:0016197 129 0.040
embryo development ending in birth or egg hatching GO:0009792 34 0.040
Mouse
hair cycle GO:0042633 28 0.040
nephron development GO:0072006 30 0.040
regulation of transporter activity GO:0032409 82 0.039
regulation of protein export from nucleus GO:0046825 15 0.039
regulation of cell activation GO:0050865 125 0.039
regulation of lipid biosynthetic process GO:0046890 47 0.039
positive regulation of cell development GO:0010720 92 0.039
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.039
nitrogen compound transport GO:0071705 191 0.039
mapk cascade GO:0000165 288 0.039
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.039
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.038

POU5F1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.806
Human
nervous system disease DOID:863 431 0.806
Human
eye and adnexa disease DOID:1492 150 0.659
eye disease DOID:5614 149 0.253
microphthalmia DOID:10629 11 0.087