|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
1.000
|
|
|
|
negative regulation of bile acid biosynthetic process
|
GO:0070858 |
3 |
1.000
|
|
|
|
drug catabolic process
|
GO:0042737 |
10 |
1.000
|
|
|
|
bile acid metabolic process
|
GO:0008206 |
14 |
0.999
|
|
|
|
negative regulation of activation of jak2 kinase activity
|
GO:1902569 |
1 |
0.999
|
|
|
|
vitamin d receptor signaling pathway
|
GO:0070561 |
4 |
0.999
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.998
|
|
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.997
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.997
|
Rat |
|
|
negative regulation of cholesterol storage
|
GO:0010887 |
4 |
0.997
|
|
|
|
xenobiotic metabolic process
|
GO:0006805 |
28 |
0.996
|
|
|
|
glycolytic process
|
GO:0006096 |
17 |
0.996
|
Rat |
|
|
drug metabolic process
|
GO:0017144 |
19 |
0.994
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.994
|
|
|
|
lipid oxidation
|
GO:0034440 |
33 |
0.994
|
Rat |
|
|
response to low density lipoprotein particle
|
GO:0055098 |
4 |
0.992
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
26 |
0.991
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.991
|
|
|
|
regulation of cholesterol storage
|
GO:0010885 |
8 |
0.990
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.990
|
Rat |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.989
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.989
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.986
|
Rat |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.984
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.982
|
|
|
|
exogenous drug catabolic process
|
GO:0042738 |
8 |
0.980
|
|
|
|
cellular response to prostaglandin stimulus
|
GO:0071379 |
4 |
0.979
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.979
|
Human |
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.978
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.975
|
Rat |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.972
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.971
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.970
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.962
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.960
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.958
|
|
|
|
drug transport
|
GO:0015893 |
8 |
0.957
|
|
|
|
xenobiotic transport
|
GO:0042908 |
1 |
0.955
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.954
|
|
|
|
bile acid biosynthetic process
|
GO:0006699 |
10 |
0.954
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.945
|
Rat |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.945
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.943
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.942
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.935
|
Rat |
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.931
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.928
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.925
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.924
|
Mouse Rat |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.924
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.923
|
Rat |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.922
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.919
|
Rat |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.912
|
Rat |
|
|
regulation of transcription involved in lymphatic endothelial cell fate commitment
|
GO:0060849 |
2 |
0.907
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.907
|
Rat |
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.906
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.901
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
6 |
0.898
|
|
|
|
response to vitamin d
|
GO:0033280 |
10 |
0.895
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.891
|
Rat |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.887
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.879
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.875
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.873
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.869
|
Rat |
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.867
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.861
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.858
|
|
|
|
lymphatic endothelial cell fate commitment
|
GO:0060838 |
2 |
0.857
|
|
|
|
negative regulation of collagen biosynthetic process
|
GO:0032966 |
2 |
0.857
|
|
|
|
regulation of sequestering of triglyceride
|
GO:0010889 |
8 |
0.856
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.851
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.845
|
|
|
|
positive regulation of fatty acid metabolic process
|
GO:0045923 |
11 |
0.843
|
Rat |
|
|
negative regulation of response to interferon gamma
|
GO:0060331 |
2 |
0.834
|
|
|
|
positive regulation of keratinocyte differentiation
|
GO:0045618 |
6 |
0.828
|
|
|
|
sequestering of triglyceride
|
GO:0030730 |
11 |
0.824
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.822
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.808
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.801
|
Rat |
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.797
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.795
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.794
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.787
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.786
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.784
|
|
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.782
|
Rat |
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.779
|
|
|
|
decidualization
|
GO:0046697 |
4 |
0.779
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.777
|
Rat |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.773
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.772
|
|
|
|
negative regulation of smooth muscle cell proliferation
|
GO:0048662 |
14 |
0.765
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.759
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.758
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.758
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.757
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.757
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.753
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.752
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.739
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.739
|
Rat |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.736
|
|
|
|
cellular response to vitamin d
|
GO:0071305 |
5 |
0.731
|
|
|
|
negative regulation of collagen metabolic process
|
GO:0010713 |
3 |
0.731
|
|
|
|
drug export
|
GO:0046618 |
1 |
0.729
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.728
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.725
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.723
|
Rat |
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.719
|
|
|
|
monocyte differentiation
|
GO:0030224 |
15 |
0.716
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.714
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.712
|
Rat |
|
|
negative regulation of sequestering of triglyceride
|
GO:0010891 |
5 |
0.711
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
17 |
0.705
|
Rat |
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.705
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.694
|
|
|
|
maternal placenta development
|
GO:0001893 |
5 |
0.686
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.680
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.680
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.679
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.678
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.677
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.676
|
|
|
|
retinoic acid receptor signaling pathway
|
GO:0048384 |
13 |
0.672
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.666
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.664
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.661
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.661
|
Rat |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.654
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.647
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.647
|
Rat |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.644
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.629
|
Rat |
|
|
positive regulation of vitamin d 24 hydroxylase activity
|
GO:0010980 |
3 |
0.628
|
|
|
|
ornithine metabolic process
|
GO:0006591 |
3 |
0.620
|
|
|
|
otic vesicle development
|
GO:0071599 |
1 |
0.620
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.617
|
Mouse Rat |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.615
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.612
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
11 |
0.608
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.592
|
Mouse Rat |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.590
|
Rat |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.589
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.589
|
|
|
|
regulation of bile acid biosynthetic process
|
GO:0070857 |
5 |
0.587
|
|
|
|
fatty acid transport
|
GO:0015908 |
25 |
0.576
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.576
|
Mouse |
|
|
acylglycerol homeostasis
|
GO:0055090 |
14 |
0.574
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.568
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.554
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.551
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.538
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.528
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.527
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.525
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.525
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.519
|
Rat |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.514
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.512
|
|
|
|
negative regulation of acute inflammatory response
|
GO:0002674 |
3 |
0.510
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.510
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.509
|
|
|
|
regulation of glycolytic by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072363 |
1 |
0.506
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.505
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.504
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.503
|
Rat |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.502
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.502
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.501
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
12 |
0.497
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.495
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.493
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.491
|
Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.491
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
8 |
0.486
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.485
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.482
|
|
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.471
|
|
|
|
regulation of fatty acid oxidation
|
GO:0046320 |
9 |
0.463
|
Rat |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.463
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.460
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.455
|
Rat |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.445
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.443
|
|
|
|
regulation of vitamin d 24 hydroxylase activity
|
GO:0010979 |
3 |
0.435
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.435
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.431
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.431
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.422
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.419
|
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
5 |
0.417
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.416
|
Mouse |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.415
|
|
|
|
long chain fatty acid transport
|
GO:0015909 |
18 |
0.413
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.407
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.401
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.400
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.397
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.394
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.392
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.392
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.385
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.384
|
|
|
|
response to lipoprotein particle
|
GO:0055094 |
5 |
0.378
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.378
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.377
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.375
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.372
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.371
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.369
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
2 |
0.365
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
24 |
0.364
|
Rat |
|
|
organic acid transport
|
GO:0015849 |
65 |
0.364
|
|
|
|
regulation of retinoic acid receptor signaling pathway
|
GO:0048385 |
9 |
0.362
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.362
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.360
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.360
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
15 |
0.357
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.355
|
|
|
|
cholesterol storage
|
GO:0010878 |
9 |
0.354
|
|
|
|
positive regulation of nitric oxide synthase activity
|
GO:0051000 |
7 |
0.348
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.348
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.347
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.345
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.344
|
Rat |
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.344
|
Rat |
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.341
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.336
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.334
|
Rat |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.329
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.324
|
Rat |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.322
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.318
|
|
|
|
placenta development
|
GO:0001890 |
10 |
0.318
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.307
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.307
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.303
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.299
|
Rat |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.299
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.298
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.296
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.293
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.292
|
Rat |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.288
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.286
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.282
|
|
|
|
system process
|
GO:0003008 |
349 |
0.282
|
|
|
|
atrial cardiac muscle tissue development
|
GO:0003228 |
1 |
0.279
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.278
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.277
|
Rat |
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.276
|
|
|
|
regulation of microvillus assembly
|
GO:0032534 |
1 |
0.276
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.276
|
|
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.274
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.273
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.272
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.269
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.268
|
|
|
|
triglyceride homeostasis
|
GO:0070328 |
14 |
0.266
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.266
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.264
|
Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.263
|
Rat |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.256
|
|
|
|
regulation of microvillus organization
|
GO:0032530 |
1 |
0.254
|
|
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.252
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.249
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.249
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.246
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.242
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.242
|
Rat |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.239
|
|
|
|
low density lipoprotein receptor particle metabolic process
|
GO:0032799 |
8 |
0.234
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.234
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.233
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.231
|
Rat |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.230
|
|
|
|
peroxisome proliferator activated receptor signaling pathway
|
GO:0035357 |
7 |
0.228
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.228
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.226
|
|
|
|
bile acid signaling pathway
|
GO:0038183 |
3 |
0.225
|
|
|
|
regulation of cellular carbohydrate catabolic process
|
GO:0043471 |
11 |
0.223
|
Rat |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.219
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.219
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.216
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.216
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.216
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.216
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.210
|
Rat |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.208
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.207
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.204
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.203
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.203
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.202
|
Rat |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.200
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.200
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.199
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.199
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.197
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.188
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.188
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.188
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.187
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.185
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.184
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
15 |
0.183
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.179
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.179
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.179
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.178
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.177
|
Rat |
|
|
immune response
|
GO:0006955 |
307 |
0.175
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.174
|
Rat |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.174
|
|
|
|
cellular response to prostaglandin e stimulus
|
GO:0071380 |
3 |
0.173
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.173
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.173
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.172
|
|
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
5 |
0.172
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.172
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.166
|
|
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
6 |
0.166
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.165
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.165
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.164
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
6 |
0.162
|
Rat |
|
|
response to vitamin
|
GO:0033273 |
13 |
0.161
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.159
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.157
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.157
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
13 |
0.157
|
|
|
|
negative regulation of dna biosynthetic process
|
GO:2000279 |
11 |
0.157
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.157
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.156
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
5 |
0.153
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.151
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.151
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.150
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.147
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.146
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.146
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.144
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.142
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.137
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.137
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.135
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.134
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.128
|
Rat |
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.128
|
|
|
|
regulation of interferon gamma mediated signaling pathway
|
GO:0060334 |
6 |
0.128
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.125
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.125
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.123
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.123
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.122
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.121
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.121
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.121
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
11 |
0.119
|
Rat |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.118
|
Rat |
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.118
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.117
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.117
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.116
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.116
|
|
|
|
growth
|
GO:0040007 |
202 |
0.114
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.113
|
|
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
7 |
0.112
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.112
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.112
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.111
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.109
|
|
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
14 |
0.108
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.108
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.108
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.107
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.106
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.106
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.106
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.105
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.105
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.105
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.105
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.104
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.104
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.104
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.103
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.103
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.102
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.101
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.101
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.099
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.099
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
11 |
0.099
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.097
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.097
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.096
|
|
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.096
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.096
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.094
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.094
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.093
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.093
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.092
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.092
|
Rat |
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.091
|
|
|
|
low density lipoprotein particle receptor biosynthetic process
|
GO:0045713 |
5 |
0.091
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.090
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.090
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.090
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.090
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.089
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.089
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.088
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.088
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.088
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.086
|
Rat |
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.086
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.086
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.086
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.085
|
|
|
|
microvillus assembly
|
GO:0030033 |
2 |
0.085
|
|
|
|
thioester metabolic process
|
GO:0035383 |
23 |
0.085
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.085
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.084
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.084
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.084
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.083
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
12 |
0.080
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.080
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.080
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.080
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.079
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.078
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.078
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.077
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.077
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.076
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.076
|
|
|
|
atrial cardiac muscle tissue morphogenesis
|
GO:0055009 |
1 |
0.076
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.076
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.075
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.075
|
Rat |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.075
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.073
|
Rat |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.072
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.072
|
Rat |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.072
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.072
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
2 |
0.071
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.071
|
|
|
|
cellular response to vitamin
|
GO:0071295 |
6 |
0.070
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.070
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.070
|
|
|
|
signal transduction involved in regulation of gene expression
|
GO:0023019 |
1 |
0.070
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.069
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
9 |
0.069
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.069
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.068
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.068
|
|
|
|
lipoprotein transport
|
GO:0042953 |
5 |
0.067
|
|
|
|
positive regulation of retinoic acid receptor signaling pathway
|
GO:0048386 |
3 |
0.067
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.067
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.065
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.065
|
|
|
|
acute inflammatory response
|
GO:0002526 |
21 |
0.064
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.064
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.063
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.063
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.063
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.063
|
|
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
3 |
0.062
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.062
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.061
|
Rat |
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.061
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.061
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.060
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
8 |
0.060
|
|
|
|
microvillus organization
|
GO:0032528 |
2 |
0.060
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.059
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
10 |
0.059
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.059
|
|
