Homo sapiens

157 known processes

PPID

peptidylprolyl isomerase D

(Aliases: CYPD,MGC33096,CYP-40)

PPID biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 14 1.000
Yeast
protein folding GO:0006457 38 0.994
chaperone cofactor dependent protein refolding GO:0070389 4 0.991
protein localization to mitochondrion GO:0070585 25 0.970
de novo protein folding GO:0006458 2 0.922
chaperone mediated protein folding GO:0061077 13 0.880
intracellular protein transmembrane transport GO:0065002 24 0.854
de novo posttranslational protein folding GO:0051084 2 0.793
establishment of protein localization to mitochondrion GO:0072655 22 0.782
mitochondrial transport GO:0006839 60 0.744
mitochondrial membrane organization GO:0007006 40 0.723
negative regulation of apoptotic process GO:0043066 316 0.670
Rat
regulation of cellular component biogenesis GO:0044087 281 0.661
mitochondrion organization GO:0007005 156 0.643
negative regulation of cell death GO:0060548 345 0.635
Rat
lung saccule development GO:0060430 2 0.591
negative regulation of programmed cell death GO:0043069 321 0.511
Rat
oxidation reduction process GO:0055114 396 0.425
nucleoside triphosphate catabolic process GO:0009143 394 0.379
protein targeting to mitochondrion GO:0006626 19 0.367
protein localization to organelle GO:0033365 280 0.340
nucleoside phosphate catabolic process GO:1901292 412 0.338
intracellular protein transmembrane import GO:0044743 23 0.316
intracellular receptor signaling pathway GO:0030522 104 0.301
cellular component morphogenesis GO:0032989 314 0.265
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.261
protein transmembrane transport GO:0071806 25 0.253
transmembrane transport GO:0055085 399 0.250
single organism cellular localization GO:1902580 332 0.247
regulation of endopeptidase activity GO:0052548 170 0.246
glycosyl compound catabolic process GO:1901658 413 0.242
locomotory behavior GO:0007626 1 0.238
organic acid biosynthetic process GO:0016053 97 0.236
ribonucleotide catabolic process GO:0009261 405 0.233
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.224
positive regulation of hydrolase activity GO:0051345 331 0.218
regulation of cellular amine metabolic process GO:0033238 11 0.213
cellular macromolecular complex assembly GO:0034622 324 0.206
determination of adult lifespan GO:0008340 2 0.203
sensory perception of pain GO:0019233 4 0.196
nucleoside catabolic process GO:0009164 408 0.190
regulation of cellular amino acid metabolic process GO:0006521 6 0.188
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.183
regulation of meiotic cell cycle GO:0051445 4 0.183
generation of precursor metabolites and energy GO:0006091 68 0.177
positive regulation of cellular amine metabolic process GO:0033240 7 0.171
positive regulation of cellular catabolic process GO:0031331 284 0.170
establishment of protein localization to membrane GO:0090150 121 0.170
ribonucleoside monophosphate catabolic process GO:0009158 158 0.163
small molecule biosynthetic process GO:0044283 157 0.160
microtubule polymerization or depolymerization GO:0031109 37 0.156
amine metabolic process GO:0009308 44 0.152
cellular amino acid metabolic process GO:0006520 116 0.145
cellular protein complex assembly GO:0043623 188 0.142
negative regulation of cellular protein metabolic process GO:0032269 353 0.140
sleep GO:0030431 2 0.137
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.129
carboxylic acid biosynthetic process GO:0046394 97 0.127
purine ribonucleotide catabolic process GO:0009154 404 0.126
post embryonic development GO:0009791 2 0.125
positive regulation of apoptotic process GO:0043065 246 0.122
protein localization to endoplasmic reticulum GO:0070972 19 0.121
purine containing compound catabolic process GO:0072523 411 0.119
nucleoside monophosphate metabolic process GO:0009123 191 0.119
response to temperature stimulus GO:0009266 22 0.118
Yeast
protein maturation GO:0051604 233 0.114
cellular macromolecule catabolic process GO:0044265 380 0.112
single organism membrane organization GO:0044802 268 0.110
apoptotic signaling pathway GO:0097190 268 0.107
nucleotide catabolic process GO:0009166 408 0.105
protein localization to membrane GO:0072657 160 0.103
purine nucleoside triphosphate metabolic process GO:0009144 412 0.099
internal peptidyl lysine acetylation GO:0018393 97 0.098
unsaturated fatty acid metabolic process GO:0033559 37 0.097
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.094
cell growth GO:0016049 160 0.094
cellular amine metabolic process GO:0044106 41 0.094
cellular heat acclimation GO:0070370 3 0.094
unsaturated fatty acid biosynthetic process GO:0006636 21 0.094
regulation of peptidase activity GO:0052547 180 0.093
rna dependent dna replication GO:0006278 16 0.091
response to peptide GO:1901652 65 0.090
cotranslational protein targeting to membrane GO:0006613 2 0.088
cellular ketone metabolic process GO:0042180 80 0.086
purine nucleoside monophosphate metabolic process GO:0009126 186 0.086
membrane organization GO:0061024 292 0.085
tissue regeneration GO:0042246 3 0.085
peptidyl lysine modification GO:0018205 144 0.084
positive regulation of catabolic process GO:0009896 310 0.084
establishment of protein localization to organelle GO:0072594 172 0.080
prostaglandin metabolic process GO:0006693 17 0.080
cell type specific apoptotic process GO:0097285 125 0.080
cytoplasmic transport GO:0016482 379 0.079
covalent chromatin modification GO:0016569 254 0.078
detection of stimulus GO:0051606 85 0.078
regulation of purine nucleotide catabolic process GO:0033121 205 0.077
microtubule polymerization GO:0046785 18 0.077
monocarboxylic acid metabolic process GO:0032787 185 0.075
cellular lipid metabolic process GO:0044255 303 0.074
negative regulation of neuron apoptotic process GO:0043524 23 0.072
cell morphogenesis GO:0000902 296 0.070
regulation of protein kinase activity GO:0045859 289 0.069
protein processing GO:0016485 226 0.069
cellular polysaccharide metabolic process GO:0044264 27 0.067
carbohydrate biosynthetic process GO:0016051 42 0.066
purine nucleoside triphosphate catabolic process GO:0009146 392 0.066
regulation of atpase activity GO:0043462 25 0.066
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.065
regulation of neuron apoptotic process GO:0043523 35 0.063
negative regulation of cellular component organization GO:0051129 235 0.063
system process GO:0003008 349 0.062
protein import GO:0017038 130 0.062
negative regulation of protein phosphorylation GO:0001933 140 0.059
protein peptidyl prolyl isomerization GO:0000413 8 0.056
negative regulation of kinase activity GO:0033673 106 0.056
single organism carbohydrate metabolic process GO:0044723 193 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.054
negative regulation of catalytic activity GO:0043086 335 0.053
regulation of ion transport GO:0043269 189 0.053
organophosphate catabolic process GO:0046434 430 0.052
response to oxygen containing compound GO:1901700 369 0.051
actin filament based process GO:0030029 224 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.049
calcium ion transport GO:0006816 147 0.048
regulation of cytokine production GO:0001817 232 0.048
purine ribonucleoside catabolic process GO:0046130 398 0.048
response to hormone GO:0009725 175 0.047
prostanoid biosynthetic process GO:0046457 11 0.047
positive regulation of peptidase activity GO:0010952 88 0.047
translation GO:0006412 132 0.047
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.047
circadian sleep wake cycle process GO:0022410 2 0.045
neuron apoptotic process GO:0051402 39 0.045
purine nucleoside catabolic process GO:0006152 398 0.044
outer mitochondrial membrane organization GO:0007008 4 0.044
establishment of protein localization to mitochondrial membrane GO:0090151 7 0.044
lipid biosynthetic process GO:0008610 177 0.044
purine nucleotide catabolic process GO:0006195 405 0.043
regulation of proteolysis GO:0030162 293 0.043
mitotic cell cycle process GO:1903047 286 0.042
positive regulation of proteolysis GO:0045862 142 0.042
regulation of cysteine type endopeptidase activity GO:2000116 127 0.042
chaperone mediated protein complex assembly GO:0051131 9 0.042
neurological system process GO:0050877 163 0.042
monocarboxylic acid biosynthetic process GO:0072330 67 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.042
fatty acid derivative metabolic process GO:1901568 35 0.041
protein acetylation GO:0006473 116 0.040
mitochondrial translation GO:0032543 17 0.040
histone modification GO:0016570 251 0.040
purine nucleoside monophosphate catabolic process GO:0009128 158 0.039
neurotransmitter secretion GO:0007269 4 0.038
immune response GO:0006955 307 0.038
protein homooligomerization GO:0051260 100 0.038
protein acylation GO:0043543 138 0.038
nuclear transport GO:0051169 179 0.038
behavior GO:0007610 112 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
negative regulation of cellular amine metabolic process GO:0033239 3 0.037
dna damage response detection of dna damage GO:0042769 3 0.037
circulatory system development GO:0072359 262 0.037
response to abiotic stimulus GO:0009628 336 0.036
activation of cysteine type endopeptidase activity GO:0097202 57 0.036
fatty acid metabolic process GO:0006631 115 0.035
ncrna processing GO:0034470 83 0.035
negative regulation of protein modification process GO:0031400 200 0.035
regulation of cell cycle GO:0051726 393 0.034
regulation of proteasomal protein catabolic process GO:0061136 87 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
regulation of mapk cascade GO:0043408 262 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
embryo development GO:0009790 123 0.033
multicellular organismal response to stress GO:0033555 1 0.033
protein targeting GO:0006605 187 0.033
neuromuscular junction development GO:0007528 3 0.033
protein oligomerization GO:0051259 173 0.032
regulation of apoptotic signaling pathway GO:2001233 175 0.032
heart process GO:0003015 62 0.032
energy derivation by oxidation of organic compounds GO:0015980 43 0.032
innate immune response GO:0045087 178 0.032
neuron death GO:0070997 65 0.032
negative regulation of neuron death GO:1901215 32 0.032
defense response GO:0006952 315 0.031
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.031
response to heat GO:0009408 21 0.031
Yeast
cell development GO:0048468 328 0.031
protein ubiquitination GO:0016567 314 0.031
fatty acid derivative biosynthetic process GO:1901570 18 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
positive regulation of cell death GO:0010942 263 0.031
regulation of mitochondrial membrane potential GO:0051881 23 0.030
Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.030
adult locomotory behavior GO:0008344 1 0.030
cell projection organization GO:0030030 252 0.030
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.029
intracellular protein transport GO:0006886 270 0.029
energy reserve metabolic process GO:0006112 22 0.029
response to unfolded protein GO:0006986 24 0.028
negative regulation of protein kinase activity GO:0006469 98 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
positive regulation of atpase activity GO:0032781 19 0.028
lipid metabolic process GO:0006629 381 0.028
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
associative learning GO:0008306 1 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
icosanoid metabolic process GO:0006690 35 0.026
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.026
zymogen activation GO:0031638 70 0.026
internal protein amino acid acetylation GO:0006475 101 0.026
regulation of cell growth GO:0001558 135 0.026
cellular protein catabolic process GO:0044257 261 0.025
histone serine phosphorylation GO:0035404 4 0.025
response to lipid GO:0033993 206 0.025
metal ion transport GO:0030001 272 0.025
regulation of kinase activity GO:0043549 314 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
cellular polysaccharide biosynthetic process GO:0033692 21 0.025
cell projection morphogenesis GO:0048858 129 0.024
fear response GO:0042596 0 0.024
receptor mediated endocytosis GO:0006898 84 0.024
oogenesis GO:0048477 2 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
androgen receptor signaling pathway GO:0030521 34 0.023
female gamete generation GO:0007292 2 0.023
cellular component assembly involved in morphogenesis GO:0010927 73 0.023
protein catabolic process GO:0030163 325 0.023
multicellular organismal aging GO:0010259 3 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
cellular carbohydrate biosynthetic process GO:0034637 21 0.022
cellular carbohydrate metabolic process GO:0044262 84 0.022
cell cell signaling GO:0007267 155 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
protein import into mitochondrial outer membrane GO:0045040 4 0.022
glycogen metabolic process GO:0005977 22 0.021
epithelium development GO:0060429 227 0.021
positive regulation of meiotic cell cycle GO:0051446 2 0.021
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.021
regulation of homeostatic process GO:0032844 121 0.021
regeneration GO:0031099 4 0.021
glycogen biosynthetic process GO:0005978 16 0.021
organ formation GO:0048645 3 0.021
modification dependent macromolecule catabolic process GO:0043632 212 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
segmentation GO:0035282 4 0.021
detection of light stimulus GO:0009583 11 0.021
proteasomal protein catabolic process GO:0010498 176 0.020
trna metabolic process GO:0006399 35 0.020
cellular glucan metabolic process GO:0006073 22 0.020
regulation of transferase activity GO:0051338 355 0.020
dna catabolic process GO:0006308 49 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
negative regulation of protein ubiquitination GO:0031397 35 0.020
positive regulation of programmed cell death GO:0043068 249 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
fatty acid biosynthetic process GO:0006633 46 0.019
myosin filament organization GO:0031033 2 0.019
secretion by cell GO:0032940 226 0.018
negative regulation of peptidase activity GO:0010466 91 0.018
peptidyl serine modification GO:0018209 106 0.018
microtubule based process GO:0007017 210 0.018
cellular response to heat GO:0034605 14 0.018
Yeast
nucleoside monophosphate catabolic process GO:0009125 159 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
negative regulation of protein maturation GO:1903318 142 0.018
response to organonitrogen compound GO:0010243 156 0.018
mitotic cell cycle GO:0000278 326 0.017
renal system development GO:0072001 63 0.017
gtp catabolic process GO:0006184 237 0.017
reproductive structure development GO:0048608 55 0.017
detection of stimulus involved in sensory perception GO:0050906 43 0.017
reproductive system development GO:0061458 56 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
regulation of cell cycle process GO:0010564 266 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
nitrogen compound transport GO:0071705 191 0.017
polysaccharide biosynthetic process GO:0000271 27 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
regulation of neuron death GO:1901214 56 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
toxin transport GO:1901998 4 0.016
positive regulation of cell cycle GO:0045787 140 0.016
tube development GO:0035295 125 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
endomembrane system organization GO:0010256 196 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
mrna transport GO:0051028 30 0.016
atp metabolic process GO:0046034 176 0.016
cell substrate adhesion GO:0031589 132 0.016
positive regulation of cell activation GO:0050867 81 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
nadh dehydrogenase complex assembly GO:0010257 16 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
regulation of protein maturation GO:1903317 150 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
protein methylation GO:0006479 74 0.016
interspecies interaction between organisms GO:0044419 156 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
regulation of cellular component movement GO:0051270 334 0.016
generation of neurons GO:0048699 152 0.015
sulfur compound biosynthetic process GO:0044272 38 0.015
heat acclimation GO:0010286 3 0.015
positive regulation of atp catabolic process GO:1903291 19 0.015
negative regulation of growth GO:0045926 97 0.015
regulation of heart growth GO:0060420 4 0.015
regulation of membrane potential GO:0042391 95 0.015
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
protein polymerization GO:0051258 71 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
striated muscle cell differentiation GO:0051146 43 0.014
apoptotic mitochondrial changes GO:0008637 57 0.014
anterior posterior axis specification GO:0009948 2 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of protein localization GO:0032880 296 0.014
rna interference GO:0016246 4 0.014
macromolecule methylation GO:0043414 97 0.014
circadian behavior GO:0048512 2 0.014
response to reactive oxygen species GO:0000302 61 0.014
protein import into mitochondrial matrix GO:0030150 1 0.014
regulation of growth GO:0040008 165 0.014
sex differentiation GO:0007548 45 0.014
actomyosin structure organization GO:0031032 59 0.013
dna replication GO:0006260 116 0.013
glucan metabolic process GO:0044042 22 0.013
icosanoid biosynthetic process GO:0046456 18 0.013
glucan biosynthetic process GO:0009250 16 0.013
golgi organization GO:0007030 38 0.013
positive regulation of locomotion GO:0040017 186 0.013
synaptic transmission GO:0007268 61 0.013
sister chromatid cohesion GO:0007062 24 0.013
multi organism transport GO:0044766 14 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
regulation of protein complex assembly GO:0043254 147 0.013
response to topologically incorrect protein GO:0035966 29 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
cellular component disassembly GO:0022411 92 0.013
muscle cell differentiation GO:0042692 63 0.013
positive regulation of cell motility GO:2000147 177 0.013
cellular response to peptide hormone stimulus GO:0071375 56 0.013
actin cytoskeleton organization GO:0030036 207 0.013
blood vessel development GO:0001568 172 0.013
positive regulation of adaptive immune response GO:0002821 21 0.013
regulation of binding GO:0051098 111 0.012
cell part morphogenesis GO:0032990 137 0.012
somitogenesis GO:0001756 2 0.012
regulation of cell motility GO:2000145 299 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
positive regulation of immune system process GO:0002684 283 0.012
divalent inorganic cation transport GO:0072511 158 0.012
trna processing GO:0008033 23 0.012
divalent metal ion transport GO:0070838 152 0.012
embryonic morphogenesis GO:0048598 85 0.012
response to radiation GO:0009314 151 0.012
maintenance of location GO:0051235 112 0.012
response to other organism GO:0051707 261 0.012
regulation of cell migration GO:0030334 289 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of locomotion GO:0040012 329 0.012
regulation of cellular response to stress GO:0080135 244 0.012
corticosteroid receptor signaling pathway GO:0031958 5 0.012
regulation of protein catabolic process GO:0042176 155 0.012
multi organism reproductive process GO:0044703 54 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of vasculature development GO:1901342 97 0.012
response to nitrogen compound GO:1901698 184 0.011
response to wounding GO:0009611 168 0.011
growth GO:0040007 202 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
myosin filament assembly GO:0031034 2 0.011
protein alkylation GO:0008213 74 0.011
response to organic cyclic compound GO:0014070 204 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
coenzyme metabolic process GO:0006732 65 0.011
viral process GO:0016032 146 0.011
detection of chemical stimulus GO:0009593 55 0.011
endocytosis GO:0006897 159 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
vesicle mediated transport GO:0016192 371 0.010
positive regulation of protein catabolic process GO:0045732 75 0.010
sensory perception GO:0007600 103 0.010
response to decreased oxygen levels GO:0036293 96 0.010
peptidyl serine phosphorylation GO:0018105 101 0.010
muscle cell development GO:0055001 29 0.010
skin development GO:0043588 76 0.010
circulatory system process GO:0003013 113 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010
regulation of map kinase activity GO:0043405 108 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
respiratory system development GO:0060541 22 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.010

PPID disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.025
nervous system disease DOID:863 431 0.025