|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.994
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.993
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.973
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.969
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.958
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.923
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.911
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.911
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.911
|
Yeast |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.891
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.887
|
Yeast |
|
|
regulation of glycogen catabolic process
|
GO:0005981 |
2 |
0.880
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.864
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.857
|
Yeast |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.848
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.835
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.801
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.782
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.763
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.750
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.741
|
Yeast |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.701
|
Yeast Mouse Fly |
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.690
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.669
|
Yeast |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.663
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.632
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.624
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.622
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.595
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.583
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.556
|
Yeast Worm |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.551
|
Yeast |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.541
|
Yeast |
|
|
dna repair
|
GO:0006281 |
198 |
0.538
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.534
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.516
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.511
|
Yeast Worm Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.508
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.488
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.486
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.471
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.455
|
Mouse Fly |
|
|
glycogen catabolic process
|
GO:0005980 |
4 |
0.446
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.442
|
Yeast |
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
15 |
0.430
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.411
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.409
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.391
|
Yeast |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.387
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.385
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.382
|
Yeast |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.379
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.377
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.375
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.343
|
Yeast |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.338
|
Yeast |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.337
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.322
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.322
|
Yeast |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.319
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.313
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.304
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.298
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.285
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.274
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.266
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.264
|
Yeast |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.262
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.259
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.249
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.243
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.242
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.242
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.240
|
Yeast |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.234
|
Yeast |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.233
|
Yeast |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.231
|
Yeast |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.227
|
Yeast |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.224
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.223
|
|
|
|
polysaccharide catabolic process
|
GO:0000272 |
4 |
0.222
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.217
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.217
|
Yeast Worm Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.216
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.211
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.211
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.211
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.201
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.197
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.195
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.187
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.185
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.181
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.179
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.176
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.176
|
Yeast |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.170
|
Yeast |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.167
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.166
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.161
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.156
|
Yeast |
|
|
transition metal ion transport
|
GO:0000041 |
23 |
0.153
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.150
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.148
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.148
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.147
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.143
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.143
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.142
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.141
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.140
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.135
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.135
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.133
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.133
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.132
|
Yeast |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.131
|
Fly |
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.129
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.123
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.121
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.119
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.114
|
Yeast Worm Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.114
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.114
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.114
|
|
|
|
aging
|
GO:0007568 |
66 |
0.113
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.113
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.112
|
Yeast |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.111
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.111
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.109
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.107
|
Yeast |
|
|
system process
|
GO:0003008 |
349 |
0.105
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.105
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.099
|
Yeast |
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.098
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.098
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.097
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.096
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.095
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.094
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.094
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.094
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.093
|
Yeast |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.092
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.092
|
|
|
|
regulation of glucan biosynthetic process
|
GO:0010962 |
14 |
0.091
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.089
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.089
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.089
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.088
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.084
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.082
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.082
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.081
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.080
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.079
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.078
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.077
|
Fly |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.077
|
Yeast |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.074
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.073
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.070
|
|
|
|
growth
|
GO:0040007 |
202 |
0.070
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.070
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.068
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.068
|
Yeast |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.066
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.066
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.066
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.065
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.062
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.062
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.062
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.061
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.061
|
Yeast |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.061
|
Yeast |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.059
|
Mouse Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.059
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.059
|
Yeast |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.058
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.058
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.058
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.056
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.056
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.056
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.056
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.056
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.055
|
Mouse |
|
|
histone methylation
|
GO:0016571 |
60 |
0.055
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.054
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.054
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.054
|
Yeast |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.054
|
Yeast |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.054
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.053
|
Yeast |
|
|
stem cell development
|
GO:0048864 |
69 |
0.053
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.053
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.052
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.052
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.052
|
Yeast Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.052
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.051
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.050
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.050
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.050
|
Yeast Worm Fly |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.050
|
|
|
|
regulation of glycogen biosynthetic process
|
GO:0005979 |
14 |
0.049
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.049
|
Yeast |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.048
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.048
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
16 |
0.048
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.048
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.047
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.047
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.046
|
Yeast |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.046
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.045
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.045
|
Yeast |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.044
|
Yeast |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.044
|
Fly |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.043
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.043
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.043
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.043
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.042
|
Yeast |
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.042
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.042
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.042
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.041
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.041
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.041
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.041
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.041
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.040
|
Mouse |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.040
|
Yeast Worm Fly |
|
|
sensory perception
|
GO:0007600 |
103 |
0.040
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.039
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.039
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.038
|
Yeast |
|
|
nuclear import
|
GO:0051170 |
106 |
0.038
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.038
|
|
|
|
trivalent inorganic cation transport
|
GO:0072512 |
4 |
0.038
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.038
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.038
|
Yeast |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.038
|
Yeast |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.037
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.037
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.036
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.036
|
Yeast |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.035
|
Yeast |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.035
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.035
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.035
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.034
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.034
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.034
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.033
|
Fly |
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.033
|
Yeast |
|
|
response to uv
|
GO:0009411 |
73 |
0.033
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.033
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.032
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.032
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.032
|
Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.032
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.032
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.031
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.031
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.031
|
|
|
|
memory
|
GO:0007613 |
3 |
0.030
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.030
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.030
|
Yeast |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.030
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.030
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.030
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.030
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.030
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.030
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.030
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.029
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.029
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.029
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.029
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.029
|
Fly |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.029
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.029
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.029
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.028
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.028
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.028
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.028
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.028
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.028
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.027
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.027
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.027
|
Yeast |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.027
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.027
|
|
|
|
ferric iron transport
|
GO:0015682 |
4 |
0.027
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.026
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.026
|
Yeast |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.026
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.026
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.026
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.025
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
16 |
0.025
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.025
|
Yeast |
|
|
pharynx development
|
GO:0060465 |
1 |
0.025
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.025
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.025
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.025
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.025
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.025
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.025
|
Fly |
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.025
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.025
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.025
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.025
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.024
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.024
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.024
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.024
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.024
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.024
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.024
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.023
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.023
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.023
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.023
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.023
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.022
|
|
|
|
base excision repair
|
GO:0006284 |
21 |
0.021
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.021
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.021
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.021
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.021
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.021
|
Yeast |
|
|
regulation of protein depolymerization
|
GO:1901879 |
22 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.021
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.021
|
Yeast |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.021
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.021
|
Yeast Worm Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.021
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.021
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.021
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.020
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.020
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.020
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.020
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.020
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.020
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.020
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.020
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.020
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.020
|
Fly |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.020
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.019
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.019
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.019
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.019
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.019
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.019
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.019
|
Yeast |
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.019
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.019
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.019
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.019
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
10 |
0.018
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.018
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.018
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.018
|
Yeast |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.018
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.018
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.018
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.017
|
Yeast |
|
|
spindle assembly
|
GO:0051225 |
29 |
0.017
|
Fly |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.017
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
Mouse |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.017
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.017
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
Yeast |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.017
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.016
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.016
|
Yeast |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.016
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.016
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.016
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.016
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.016
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.016
|
Yeast |
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.016
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.016
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.016
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.016
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.015
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.015
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.015
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.015
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.015
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.015
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.015
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.015
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.015
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.015
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.015
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.015
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.015
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.015
|
Mouse |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.015
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.015
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.015
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.015
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.014
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.014
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.014
|
Yeast Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.014
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.014
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.014
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.014
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.014
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.014
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.014
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.014
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.014
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.014
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
42 |
0.014
|
Fly |
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.014
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.014
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.014
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.014
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.014
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.014
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.013
|
Rat Fly |
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.013
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.013
|
Yeast |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.013
|
Yeast |
|
|
interaction with host
|
GO:0051701 |
42 |
0.013
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.013
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.013
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.013
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.013
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.013
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.013
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.012
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.012
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.012
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.012
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.012
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.012
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.012
|
|
|
|
iron ion transport
|
GO:0006826 |
12 |
0.012
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.012
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.012
|
Fly |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.012
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.012
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.012
|
Yeast |
|
|
respiratory system development
|
GO:0060541 |
22 |
0.012
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.012
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.012
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.012
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.012
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.011
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.011
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.011
|
Worm |
|
|
signal release
|
GO:0023061 |
70 |
0.011
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.011
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.011
|
|
|
|
head development
|
GO:0060322 |
108 |
0.011
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.011
|
Yeast |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.011
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.011
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.011
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.011
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.011
|
|
|
|
dna synthesis involved in dna repair
|
GO:0000731 |
6 |
0.011
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.011
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.011
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.011
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.011
|
|
