|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.990
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.985
|
Human Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.964
|
Yeast Worm |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.955
|
Worm |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.953
|
Yeast Worm |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.952
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.936
|
Worm |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.876
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.875
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.829
|
Worm |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.827
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.825
|
Worm |
|
|
organelle fission
|
GO:0048285 |
149 |
0.824
|
Yeast Worm |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.813
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.812
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.811
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.795
|
Worm |
|
|
oogenesis
|
GO:0048477 |
2 |
0.792
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.784
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.782
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.775
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.774
|
Yeast |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.763
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.758
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.756
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.746
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.742
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.733
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.732
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.710
|
Worm |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.707
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.700
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.676
|
Yeast |
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.672
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.657
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.643
|
Yeast Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.640
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.635
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.624
|
Yeast Mouse |
|
|
neuroblast division
|
GO:0055057 |
1 |
0.622
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.613
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.593
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.589
|
Yeast |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.586
|
Yeast |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.583
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.579
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.565
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.560
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.560
|
Yeast |
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.554
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.553
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.553
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.549
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.547
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.541
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.538
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.536
|
Yeast |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.507
|
Yeast |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.504
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.503
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.494
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.484
|
Yeast |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.467
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.465
|
Yeast |
|
|
nervous system development
|
GO:0007399 |
293 |
0.459
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.458
|
Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.456
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.451
|
Worm |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.449
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.445
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.420
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.416
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.407
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.404
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.390
|
Yeast |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.384
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.375
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.370
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.369
|
Human Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.354
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.347
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.344
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.342
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.336
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.330
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.329
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.328
|
Yeast Worm |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.326
|
Yeast |
|
|
demethylation
|
GO:0070988 |
37 |
0.324
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.317
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.312
|
Human Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.311
|
Yeast |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.310
|
Yeast |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.302
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.298
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.298
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.297
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.284
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.276
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.276
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.276
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.271
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.270
|
Yeast |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.268
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.265
|
Worm |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.265
|
Yeast |
|
|
nuclear envelope reassembly
|
GO:0031468 |
3 |
0.263
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.255
|
|
|
|
positive regulation of dephosphorylation
|
GO:0035306 |
26 |
0.252
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.251
|
Yeast Worm |
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.248
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.248
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.248
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.247
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.244
|
Worm |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.243
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.238
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.238
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.236
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.229
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.227
|
Yeast |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.227
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.224
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.221
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.212
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.211
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.211
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.210
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.208
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.204
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.204
|
Yeast |
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.203
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.200
|
Worm |
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.200
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.199
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.198
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.197
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.197
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.196
|
Worm |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.194
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.194
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.194
|
Yeast Worm |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.194
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.189
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.185
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.182
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.181
|
Yeast |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.181
|
Yeast |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.178
|
Human Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.177
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.177
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.177
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.172
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.169
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.168
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.167
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.167
|
Yeast |
|
|
membrane organization
|
GO:0061024 |
292 |
0.161
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.159
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.156
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.152
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.151
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.150
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.149
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.146
|
Yeast |
|
|
dna repair
|
GO:0006281 |
198 |
0.144
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.143
|
Worm |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.143
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.142
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.141
|
Worm |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.140
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.140
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.140
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.139
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.138
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.137
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.137
|
Yeast |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.136
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.135
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.133
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.132
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.132
|
Worm |
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
7 |
0.132
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.130
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.130
|
Yeast |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.130
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.129
|
Yeast |
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.127
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.126
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.126
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.126
|
Yeast |
|
|
gonad development
|
GO:0008406 |
34 |
0.125
|
Worm |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.124
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.121
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.120
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.119
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.119
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.118
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.118
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.118
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.118
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.117
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.116
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.116
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.114
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.114
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.113
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.113
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.112
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.111
|
Yeast |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.111
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.111
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.111
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.110
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.110
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.109
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.107
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.107
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.107
|
Yeast |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.107
|
Yeast |
|
|
autophagy
|
GO:0006914 |
88 |
0.106
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.102
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.101
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.101
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.101
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.100
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.100
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.098
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.098
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.097
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.096
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.095
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.094
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.094
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.093
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.092
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.092
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.092
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.091
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.091
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.090
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.089
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.089
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.087
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.087
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.085
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.084
|
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
28 |
0.083
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.083
|
Worm |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.082
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.081
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.081
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.081
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.080
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.080
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.080
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.079
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.079
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.078
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.078
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.076
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.076
|
Human Mouse |
|
|
protein maturation
|
GO:0051604 |
233 |
0.076
|
Yeast |
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.074
|
Worm |
|
|
aging
|
GO:0007568 |
66 |
0.072
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.072
|
Yeast |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.071
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.070
|
|
|
|
growth
|
GO:0040007 |
202 |
0.070
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.070
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.068
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.068
|
Yeast |
|
|
single fertilization
|
GO:0007338 |
11 |
0.068
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.067
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.066
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.066
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.066
|
|
|
|
positive regulation of protein dephosphorylation
|
GO:0035307 |
16 |
0.066
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.065
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.065
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.065
|
Worm |
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.065
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.064
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.064
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.062
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.062
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.062
|
Yeast |
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.061
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.061
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.061
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.060
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.060
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.060
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.059
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.059
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.059
|
Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.058
|
Yeast |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.058
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.057
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.057
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.056
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.056
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.056
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.056
|
Worm |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.056
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
Human Mouse |
|
|
amide transport
|
GO:0042886 |
76 |
0.055
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.055
|
|
|
|
mitotic nuclear envelope reassembly
|
GO:0007084 |
3 |
0.054
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.054
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.054
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.054
|
|
|
|
negative regulation of protein k63 linked ubiquitination
|
GO:1900045 |
4 |
0.054
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.054
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.054
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.053
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.053
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.053
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.052
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.051
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.051
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.051
|
Human Mouse |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.051
|
|
|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.050
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.050
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.050
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.049
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.049
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.049
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.048
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.047
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.047
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.046
|
|
|
|
positive regulation of phosphoprotein phosphatase activity
|
GO:0032516 |
9 |
0.046
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.046
|
Yeast |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.046
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.046
|
|
|
|
negative regulation of calcium ion transmembrane transporter activity
|
GO:1901020 |
11 |
0.045
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
15 |
0.045
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.043
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.042
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.042
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.041
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.041
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.041
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.041
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.041
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.040
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.040
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.039
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.039
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.038
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.038
|
|
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.038
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.038
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.037
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.037
|
|
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
23 |
0.037
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.035
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.035
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.034
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.034
|
|
|
|
glycogen catabolic process
|
GO:0005980 |
4 |
0.034
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.034
|
|
|
|
negative regulation of cytokinesis
|
GO:0032466 |
3 |
0.033
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.033
|
Worm |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.032
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.032
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.032
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.032
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.032
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.031
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.031
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.031
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.030
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.030
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.030
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.030
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.030
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.029
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.029
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.029
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.029
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.029
|
|
|
|
negative regulation of calcium ion transmembrane transport
|
GO:1903170 |
11 |
0.029
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.028
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.028
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.028
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.028
|
Human Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.028
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.027
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.027
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.027
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.027
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.027
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.027
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.026
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.026
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.026
|
|
|
|
response to glucose
|
GO:0009749 |
19 |
0.026
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.026
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.025
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.025
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.025
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.025
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.025
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.024
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.024
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.024
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.024
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.024
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.024
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.023
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.023
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.023
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.023
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.023
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.023
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.023
|
|
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.023
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.023
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.023
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.023
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.022
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.022
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.022
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.022
|
Human Mouse |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.022
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.022
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.022
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
11 |
0.022
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.022
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
18 |
0.022
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.022
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.021
|
Human Mouse |
|
|
gland development
|
GO:0048732 |
48 |
0.021
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.021
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.021
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.021
|
|
|
|
head development
|
GO:0060322 |
108 |
0.020
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.020
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.020
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.020
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.020
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.020
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.019
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.019
|
Yeast |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.019
|
|
|
|
response to lead ion
|
GO:0010288 |
1 |
0.019
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.019
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
10 |
0.019
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.019
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.019
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.018
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.018
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.018
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.018
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.018
|
Worm |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.018
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.018
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.018
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.018
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.018
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.018
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.017
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.017
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.017
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.017
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.017
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.017
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.017
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.017
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.017
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.017
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.017
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.017
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.017
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.017
|
Yeast |
|
|
positive regulation of glucocorticoid receptor signaling pathway
|
GO:2000324 |
1 |
0.017
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.017
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.017
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.016
|
|
