|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.997
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.995
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.991
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.986
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.982
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.981
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.977
|
Human |
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.975
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.975
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.974
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.971
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.970
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.967
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.964
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.964
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.960
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.958
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.950
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.943
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.942
|
Human |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.940
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.939
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.932
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.925
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.922
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.922
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.922
|
Human |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.916
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.915
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.894
|
Human |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.892
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.891
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.890
|
Human |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.885
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.879
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.875
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.875
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.875
|
Human |
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.874
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.872
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.863
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.855
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.834
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.834
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.830
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.827
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.826
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.817
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.793
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.792
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.792
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.791
|
|
|
|
response to nitrosative stress
|
GO:0051409 |
4 |
0.789
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.785
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.783
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.781
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.775
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.764
|
Human |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.763
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.754
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.747
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.741
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.738
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.736
|
Human |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.728
|
Human |
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.720
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.714
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.707
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.705
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.696
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.685
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.683
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.677
|
Human |
|
|
spindle assembly
|
GO:0051225 |
29 |
0.668
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.652
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.651
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.651
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.649
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.647
|
Human |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.642
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.640
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.637
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.605
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.582
|
Worm |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.579
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.575
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.574
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.571
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.563
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.552
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.543
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.541
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.533
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.532
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.526
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.514
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.512
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.506
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.501
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.499
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.496
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.496
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.488
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.485
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.465
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.464
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.463
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.459
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.458
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.450
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.447
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.446
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.440
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.437
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.437
|
Worm |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.422
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.417
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.413
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.413
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.411
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.408
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.407
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.401
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.400
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.395
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.372
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.364
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.360
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.358
|
|
|
|
system process
|
GO:0003008 |
349 |
0.349
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.347
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.341
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.338
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.328
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.328
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.326
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.320
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.317
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.313
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.310
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.310
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.302
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.301
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.300
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.293
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.292
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.282
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.280
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.279
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.278
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.276
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.276
|
|
|
|
positive regulation of dephosphorylation
|
GO:0035306 |
26 |
0.276
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.275
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.269
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.268
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.260
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.258
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.257
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.253
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.248
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.247
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.246
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.242
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.239
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.236
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.235
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.234
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.229
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.229
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.228
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.228
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.228
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.227
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.225
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.224
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.213
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.212
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.210
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.210
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.206
|
Worm |
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.205
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.205
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.205
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.204
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.202
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.202
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.198
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.197
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.194
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.192
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.191
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.190
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.189
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.189
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.184
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.183
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.182
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.181
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.179
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.178
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.178
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.177
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.173
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.172
|
|
|
|
aging
|
GO:0007568 |
66 |
0.171
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.169
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.168
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.166
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.165
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.164
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.162
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.159
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.157
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.156
|
|
|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.156
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.155
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.154
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.150
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.148
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.147
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.145
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.141
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.141
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.139
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.138
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.137
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.136
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.136
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.136
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.135
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.132
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.132
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.132
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.130
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.130
|
|
|
|
mitotic nuclear envelope reassembly
|
GO:0007084 |
3 |
0.129
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.127
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.127
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.126
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.125
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.124
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.124
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.123
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.122
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.120
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.118
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.118
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.118
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.116
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.115
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.115
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.112
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.112
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.111
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.110
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.110
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.109
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.108
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.106
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.102
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.102
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.101
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.101
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.099
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.099
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.098
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.098
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.098
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.096
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.095
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.095
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.093
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.093
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.093
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.092
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.092
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.091
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.090
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.089
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.089
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.088
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.088
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.086
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.086
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.086
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.086
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.085
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.083
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.082
|
|
|
|
positive regulation of protein dephosphorylation
|
GO:0035307 |
16 |
0.082
|
Human |
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.081
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.081
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.080
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.079
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.079
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.079
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.079
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.077
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.076
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.076
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.076
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.076
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.075
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.075
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.075
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.074
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.074
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.074
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.073
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.073
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.072
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.072
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.071
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.071
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.071
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.071
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.071
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.070
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.069
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.069
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.069
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.068
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.068
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.068
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.068
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.068
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.068
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.067
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.066
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.066
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.066
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.066
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.064
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.064
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.064
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.064
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.063
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.063
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.061
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.061
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.061
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.060
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.059
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.058
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.058
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.058
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.057
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.056
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.056
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.056
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.056
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.056
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.055
|
|
|
|
negative regulation of calcium ion transmembrane transporter activity
|
GO:1901020 |
11 |
0.055
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.055
|
|
|
|
growth
|
GO:0040007 |
202 |
0.054
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.054
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.053
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.052
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.052
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.051
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.051
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.051
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.051
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.051
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.051
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.050
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.050
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.050
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.050
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.050
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.050
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.049
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.049
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.049
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.049
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.048
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.048
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.048
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.048
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.048
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.048
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.048
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.047
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.047
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.047
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.047
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.047
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.046
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.046
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.045
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.045
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.045
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.045
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.045
|
|
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.044
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.044
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.044
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.044
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.044
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.043
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.043
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.043
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.043
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.043
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.043
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.043
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.042
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.042
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.041
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.041
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.041
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.041
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.041
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.040
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.040
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.040
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.039
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.039
|
Human |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.039
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.039
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.038
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.038
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.038
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.038
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.037
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.037
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.037
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.037
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.037
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.037
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.037
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.036
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.036
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.036
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.036
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.036
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.035
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.035
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.035
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.035
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.035
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.035
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.035
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.034
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.034
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.034
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.033
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.033
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.033
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.033
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.033
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.033
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.033
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.032
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.032
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.032
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.032
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.032
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.031
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.031
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.031
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.031
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.030
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.030
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.030
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.030
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.030
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.030
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.030
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.030
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.030
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.030
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.029
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.029
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.029
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.029
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.029
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.029
|
|
|
|
mitotic spindle assembly checkpoint
|
GO:0007094 |
14 |
0.028
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.028
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.028
|
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
22 |
0.028
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.028
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.028
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.027
|
|
|
|
peroxisome degradation
|
GO:0030242 |
1 |
0.027
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
11 |
0.027
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.027
|
|
