|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.925
|
Human |
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.902
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.878
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.810
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.658
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.627
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.584
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.564
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.534
|
Human |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.527
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.493
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.470
|
Human |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.419
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.389
|
Human |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.375
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.336
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.326
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.323
|
Worm |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.322
|
Human |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.311
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.290
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.266
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.261
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.259
|
Human |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.246
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.231
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.221
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.218
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.216
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.215
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.194
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.183
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.179
|
Human |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.179
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.174
|
Human |
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.168
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.164
|
Human |
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.164
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.163
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.161
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.155
|
Fly |
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.146
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.145
|
|
|
|
negative regulation of stress fiber assembly
|
GO:0051497 |
8 |
0.140
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.135
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.134
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.133
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.132
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.131
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.129
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.128
|
Human |
|
|
negative regulation of protein localization to plasma membrane
|
GO:1903077 |
13 |
0.126
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.125
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.125
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.125
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.124
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.123
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.123
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.121
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.117
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.117
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.113
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.113
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.113
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.110
|
Fly |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.109
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.107
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.107
|
Human |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.106
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.105
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.100
|
Human |
|
|
axon extension involved in axon guidance
|
GO:0048846 |
5 |
0.099
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.098
|
|
|
|
microtubule based transport
|
GO:0010970 |
21 |
0.096
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.094
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.093
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.092
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.091
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.091
|
Human |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.090
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.089
|
|
|
|
negative regulation of actin filament bundle assembly
|
GO:0032232 |
9 |
0.088
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.088
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.086
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.086
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.086
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.085
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.085
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.085
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.082
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.082
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.079
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.079
|
Human |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.078
|
Human |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.077
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.076
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.075
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.074
|
Human |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.074
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.072
|
Human |
|
|
spindle assembly
|
GO:0051225 |
29 |
0.070
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.068
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.068
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.068
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.066
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.066
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.066
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.065
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.065
|
|
|
|
growth
|
GO:0040007 |
202 |
0.064
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.064
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.063
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.063
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.062
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.062
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.061
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.061
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.060
|
Human |
|
|
reproduction
|
GO:0000003 |
63 |
0.059
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.058
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.058
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.058
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.057
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.056
|
Human |
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.056
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.055
|
Human |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.055
|
Human |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.054
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.054
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.054
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.054
|
Human |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.053
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.053
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.052
|
Human |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.052
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.050
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.050
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.049
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.049
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.048
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.048
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.048
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.047
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.047
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.047
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.047
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.046
|
Human |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.046
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.046
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.045
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.044
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.044
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.044
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.044
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.043
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.043
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.042
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.042
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.042
|
Human |
|
|
spindle organization
|
GO:0007051 |
53 |
0.042
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.042
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.042
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.040
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.040
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.040
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.039
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.039
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.039
|
|
|
|
phosphatidic acid biosynthetic process
|
GO:0006654 |
4 |
0.038
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.038
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.038
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.038
|
Human |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.037
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.037
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.037
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.037
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.037
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.036
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.035
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.035
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.034
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.034
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.034
|
Human |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.033
|
Human |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.033
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.033
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.032
|
Human |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.032
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.032
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.032
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.031
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.031
|
|
|
|
negative regulation of mitotic sister chromatid separation
|
GO:2000816 |
17 |
0.031
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.031
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.030
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.030
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.030
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.030
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.030
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.029
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.029
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.029
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.029
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.029
|
Human |
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.029
|
Human |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.029
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.028
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.028
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.028
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.028
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.027
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.027
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.027
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.027
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.027
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.027
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.026
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.026
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.026
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.026
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.026
|
Worm |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.026
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.026
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.026
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.026
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.026
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.025
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.025
|
|
|
|
neuron projection extension involved in neuron projection guidance
|
GO:1902284 |
5 |
0.025
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.025
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.025
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.025
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.025
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.025
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.024
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.024
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.024
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.024
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.024
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.024
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.023
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.023
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.023
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.023
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.023
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.023
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.022
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.022
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.022
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.022
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.022
|
Human |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.022
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.022
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.022
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.021
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.021
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.021
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.021
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.021
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.021
|
Human |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.021
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.021
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.021
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.020
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.020
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.020
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.020
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.020
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.020
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.020
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.020
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.019
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.019
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.019
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.019
|
|
|
|
negative regulation of epithelial to mesenchymal transition
|
GO:0010719 |
14 |
0.019
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
18 |
0.019
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.018
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.018
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.018
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.018
|
Human |
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.018
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.018
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.018
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.017
|
Human |
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.017
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.017
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.017
|
|
|
|
peptidyl glutamic acid modification
|
GO:0018200 |
4 |
0.017
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.017
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.017
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.017
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.017
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.017
|
Human |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.017
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.017
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.017
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.017
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.017
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.017
|
Human |
|
|
organ formation
|
GO:0048645 |
3 |
0.017
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.017
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.017
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
18 |
0.016
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.016
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.016
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.016
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.016
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.016
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.016
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.016
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.016
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.016
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.016
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.016
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.016
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.016
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.015
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.015
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.015
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.015
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.015
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.015
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.015
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.015
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.015
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.015
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.015
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.014
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.014
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.014
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.014
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.014
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.014
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.014
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.014
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.014
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.014
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.014
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.014
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.014
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.014
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.014
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.014
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.014
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.014
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.014
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.014
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.013
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.013
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.013
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.013
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.013
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.013
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.013
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.013
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.013
|
|
|
|
nuclear envelope reassembly
|
GO:0031468 |
3 |
0.013
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.013
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.013
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.013
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.013
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.013
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.013
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.013
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.013
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.013
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.013
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.013
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.013
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.013
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.013
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.013
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.012
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.012
|
|
|
|
multi organism behavior
|
GO:0051705 |
14 |
0.012
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.012
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.012
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.012
|
|
|
|
protein deglutamylation
|
GO:0035608 |
1 |
0.012
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.012
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.012
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.012
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.012
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.012
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.012
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.012
|
Human |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.012
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.012
|
|
|
|
regulation of axon extension
|
GO:0030516 |
7 |
0.012
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.012
|
Human |
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.011
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.011
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.011
|
|
|
|
respiratory burst
|
GO:0045730 |
12 |
0.011
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.011
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.011
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.011
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.011
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.011
|
|
|
|
negative regulation of metaphase anaphase transition of cell cycle
|
GO:1902100 |
17 |
0.011
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.011
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.011
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.011
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.011
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.011
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.011
|
|
|
|
regulation of cell size
|
GO:0008361 |
19 |
0.011
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.011
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.011
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.011
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.011
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.011
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.011
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.011
|
|
|
|
phosphatidic acid metabolic process
|
GO:0046473 |
5 |
0.011
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.011
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.011
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.011
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.011
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.011
|
|
|
|
mitotic spindle assembly checkpoint
|
GO:0007094 |
14 |
0.011
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.011
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.010
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.010
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.010
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.010
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.010
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.010
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.010
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.010
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.010
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.010
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.010
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.010
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.010
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.010
|
Human |
|
|
protein acylation
|
GO:0043543 |
138 |
0.010
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.010
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.010
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.010
|
|
