|
|
cellular response to superoxide
|
GO:0071451 |
6 |
0.999
|
Human Mouse |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.998
|
|
|
|
cellular response to oxygen radical
|
GO:0071450 |
6 |
0.982
|
Human Mouse |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.956
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.952
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.946
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.936
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.920
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.893
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.884
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.882
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.868
|
|
|
|
protein oxidation
|
GO:0018158 |
5 |
0.864
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.859
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.801
|
Human |
|
|
superoxide metabolic process
|
GO:0006801 |
20 |
0.787
|
Human Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.764
|
Yeast |
|
|
hydrogen peroxide catabolic process
|
GO:0042744 |
13 |
0.747
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.745
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.735
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.708
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.707
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.700
|
|
|
|
negative regulation of hydrogen peroxide induced cell death
|
GO:1903206 |
9 |
0.682
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.668
|
Worm |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.652
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.635
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.629
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.626
|
Worm |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.626
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.620
|
Human |
|
|
positive regulation of superoxide anion generation
|
GO:0032930 |
4 |
0.598
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.585
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.547
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.543
|
|
|
|
cell death in response to hydrogen peroxide
|
GO:0036474 |
10 |
0.542
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.527
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.518
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.498
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.494
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.490
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.450
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.446
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.439
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.427
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.425
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.419
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.416
|
Human |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.415
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.411
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.404
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.390
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.379
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.378
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
178 |
0.365
|
Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.357
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.349
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.348
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.346
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.343
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.339
|
Human |
|
|
peptidyl cysteine modification
|
GO:0018198 |
9 |
0.337
|
Human |
|
|
primary alcohol metabolic process
|
GO:0034308 |
17 |
0.337
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.333
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.332
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.330
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.328
|
Mouse |
|
|
response to thyroid hormone
|
GO:0097066 |
9 |
0.305
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.300
|
Worm |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.292
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.290
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.287
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.287
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.274
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.273
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.273
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.271
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.258
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.254
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.254
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.253
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.239
|
|
|
|
regulation of superoxide metabolic process
|
GO:0090322 |
6 |
0.238
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.234
|
Mouse |
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
4 |
0.233
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.232
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.228
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.222
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.218
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.212
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.209
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.208
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.204
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.201
|
Worm |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.199
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.198
|
|
|
|
cellular modified amino acid biosynthetic process
|
GO:0042398 |
15 |
0.197
|
|
|
|
regulation of hydrogen peroxide induced cell death
|
GO:1903205 |
10 |
0.193
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.192
|
Human |
|
|
aging
|
GO:0007568 |
66 |
0.191
|
Yeast Worm |
|
|
response to hormone
|
GO:0009725 |
175 |
0.184
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.182
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.177
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.175
|
Mouse |
|
|
response to superoxide
|
GO:0000303 |
6 |
0.170
|
Human Mouse |
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.170
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.165
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.164
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.163
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.160
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.157
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.153
|
|
|
|
catecholamine uptake involved in synaptic transmission
|
GO:0051934 |
4 |
0.150
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.147
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.144
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.143
|
|
|
|
growth
|
GO:0040007 |
202 |
0.141
|
Worm |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.138
|
|
|
|
dopamine transport
|
GO:0015872 |
5 |
0.137
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.136
|
Human |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.135
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.135
|
Mouse |
|
|
system process
|
GO:0003008 |
349 |
0.134
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.127
|
|
|
|
response to oxygen radical
|
GO:0000305 |
6 |
0.126
|
Human Mouse |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.126
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.125
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.125
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.123
|
Human |
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.123
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.121
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.120
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.119
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.119
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.118
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.115
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.112
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.112
|
|
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
20 |
0.110
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.110
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.107
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.106
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.105
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.104
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.102
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.101
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.101
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.101
|
Mouse |
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.101
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.101
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.099
|
|
|
|
dopamine biosynthetic process
|
GO:0042416 |
4 |
0.099
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.098
|
Mouse |
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.095
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.093
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
37 |
0.092
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.090
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.089
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.089
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.089
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.085
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.085
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.084
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.082
|
|
|
|
proteasomal ubiquitin independent protein catabolic process
|
GO:0010499 |
3 |
0.082
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.082
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.079
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.078
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.078
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.078
|
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
20 |
0.077
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.077
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.076
|
|
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.076
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.075
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.073
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.073
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.072
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.071
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.069
|
Human |
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.066
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.066
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.065
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.064
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.064
|
|
|
|
aldehyde catabolic process
|
GO:0046185 |
5 |
0.064
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.063
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.063
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.063
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.063
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.062
|
|
|
|
negative regulation of response to reactive oxygen species
|
GO:1901032 |
10 |
0.062
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.062
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.062
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.062
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.062
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.062
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.061
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.061
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.061
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.060
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.060
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.060
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.060
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.059
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.059
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.059
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.058
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.058
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.057
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.057
|
|
|
|
glutathione metabolic process
|
GO:0006749 |
20 |
0.056
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.056
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
21 |
0.055
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.054
|
Worm |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.054
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.054
|
Worm |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.053
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.053
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.053
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.052
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.052
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.052
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.051
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.051
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.051
|
|
|
|
positive regulation of response to oxidative stress
|
GO:1902884 |
7 |
0.050
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.049
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.049
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.049
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.048
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.048
|
|
|
|
positive regulation of dna binding
|
GO:0043388 |
17 |
0.047
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.046
|
Worm |
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.046
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.045
|
Human |
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.045
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.045
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.045
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.045
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.044
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.044
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.044
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.043
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.043
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.043
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.042
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
159 |
0.041
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.041
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.040
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.040
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.040
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.040
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.039
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.039
|
Mouse |
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.038
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.038
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.037
|
Worm |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.037
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.037
|
Mouse |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.037
|
Worm |
|
|
skin development
|
GO:0043588 |
76 |
0.037
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.037
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.037
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.036
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.036
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.036
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.036
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.036
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.036
|
|
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.036
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.036
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.036
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.035
|
|
|
|
negative regulation of protein phosphatase type 2b activity
|
GO:0032513 |
2 |
0.035
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.035
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.034
|
|
|
|
multicellular organism growth
|
GO:0035264 |
8 |
0.034
|
Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.034
|
Human |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.034
|
Human |
|
|
inflammatory response
|
GO:0006954 |
79 |
0.034
|
|
|
|
ethanol metabolic process
|
GO:0006067 |
5 |
0.033
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.033
|
Human |
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.032
|
|
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
6 |
0.031
|
Worm |
|
|
response to amino acid
|
GO:0043200 |
14 |
0.031
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.031
|
Worm |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.031
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.031
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.031
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.030
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.030
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.030
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
35 |
0.030
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.030
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.030
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.030
|
Yeast |
|
|
ethanol oxidation
|
GO:0006069 |
5 |
0.030
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.029
|
Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.029
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.029
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.028
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.028
|
Mouse |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.028
|
Human |
|
|
response to drug
|
GO:0042493 |
81 |
0.028
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.027
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.027
|
Mouse |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.027
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.027
|
Mouse |
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.027
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.027
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.027
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.027
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.026
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.026
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.026
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.026
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.026
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.026
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.025
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.025
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.025
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.025
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.024
|
Mouse |
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.024
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
10 |
0.024
|
|
|
|
sterol biosynthetic process
|
GO:0016126 |
10 |
0.024
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
xenobiotic metabolic process
|
GO:0006805 |
28 |
0.024
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.024
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.023
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.023
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.023
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.023
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.023
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.023
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.023
|
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
30 |
0.023
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.023
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.023
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.023
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.023
|
|
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
7 |
0.023
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.023
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.023
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.023
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.023
|
|
|
|
catecholamine biosynthetic process
|
GO:0042423 |
4 |
0.022
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.022
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.022
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.022
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.022
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.022
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.022
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.022
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.022
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.022
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.021
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.021
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.021
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.021
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.021
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.021
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.021
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.021
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.020
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.020
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
15 |
0.020
|
|
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.020
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.020
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.020
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.020
|
Mouse |
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.020
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.020
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.019
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.019
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.019
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.019
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.019
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.019
|
|
|
|
neuron cellular homeostasis
|
GO:0070050 |
3 |
0.019
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.018
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.018
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.018
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.018
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.018
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.018
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.018
|
|
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
14 |
0.018
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.018
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.017
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.017
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.017
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.017
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.017
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.017
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.017
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.017
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.017
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.017
|
Human |
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.016
|
Worm |
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.016
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.016
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.016
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.016
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.016
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.016
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.016
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.016
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.016
|
|
|
|
steroid catabolic process
|
GO:0006706 |
10 |
0.016
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.016
|
|
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.016
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.016
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.016
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.016
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.015
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.015
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.015
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.015
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.015
|
Human |
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.015
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.015
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.015
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.015
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.015
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.015
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.014
|
Worm |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.014
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.014
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.014
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.014
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.014
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.014
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.014
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.014
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.014
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.014
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.014
|
|
|
|
viral genome replication
|
GO:0019079 |
50 |
0.013
|
|
|
|
response to glucose
|
GO:0009749 |
19 |
0.013
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.013
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.013
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.013
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.013
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.013
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.013
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.013
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.013
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.013
|
Mouse |
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.013
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.013
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.013
|
Human |
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.013
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.013
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.013
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.012
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.012
|
|
|
|
catecholamine uptake
|
GO:0090493 |
4 |
0.012
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.012
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.012
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.012
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.012
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.012
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.012
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.012
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.012
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.012
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.012
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.012
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.012
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.012
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.012
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.011
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.011
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.011
|
|
