|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.823
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.815
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.778
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.771
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.768
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.760
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.674
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.669
|
Mouse Worm Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.667
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.665
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.661
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.651
|
Mouse |
|
|
segmentation
|
GO:0035282 |
4 |
0.649
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.643
|
Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.643
|
Yeast |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.613
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.597
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.594
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.541
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.534
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.522
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.511
|
Mouse |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.508
|
Human Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.494
|
Human Fly |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.473
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.472
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.468
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.462
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.455
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.453
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.449
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.438
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.436
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.430
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
14 |
0.424
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.422
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.420
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.415
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.396
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.393
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.390
|
Mouse Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.381
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.377
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.372
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.367
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.366
|
Worm Fly |
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.354
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.352
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.343
|
Human |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.339
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.338
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.335
|
Fly |
|
|
system process
|
GO:0003008 |
349 |
0.332
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.323
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.322
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.316
|
Mouse |
|
|
right ventricular cardiac muscle tissue morphogenesis
|
GO:0003221 |
2 |
0.308
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.293
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.292
|
Human |
|
|
positive regulation of heart rate
|
GO:0010460 |
4 |
0.290
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.284
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.282
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.281
|
Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.278
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.275
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.273
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.268
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.260
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.259
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.258
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.257
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.244
|
Fly |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.244
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.235
|
Worm Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.233
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.231
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.228
|
Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.228
|
Human Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.227
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.222
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.222
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.222
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.221
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.220
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.218
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.218
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.214
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.214
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.213
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.212
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.209
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.208
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.208
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.208
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.204
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.199
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.198
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.196
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.195
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.193
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.193
|
Human |
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.193
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.190
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.189
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.189
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.186
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.185
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.183
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.181
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.179
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.178
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.177
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.176
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.175
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.175
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.171
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.170
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.167
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.167
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.167
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.163
|
Mouse |
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.163
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.162
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.162
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.161
|
Worm |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.161
|
|
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.161
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.160
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.159
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.159
|
Mouse |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.158
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.158
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.156
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.153
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.153
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.153
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.152
|
Fly |
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
4 |
0.151
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.149
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.147
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.147
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.147
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.147
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.144
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.142
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.141
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.141
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.139
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.138
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.138
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.136
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.135
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.135
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.134
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.134
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.133
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.131
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.131
|
Rat |
|
|
renal system development
|
GO:0072001 |
63 |
0.130
|
Human |
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.127
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.127
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.126
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.125
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.125
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.123
|
|
|
|
regulation of camp dependent protein kinase activity
|
GO:2000479 |
9 |
0.122
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.122
|
Fly |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.119
|
Mouse |
|
|
response to caffeine
|
GO:0031000 |
3 |
0.119
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.119
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.118
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.117
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.116
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.114
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.114
|
Mouse Fly |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.112
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.112
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.111
|
Mouse |
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.111
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.111
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.110
|
Mouse Rat |
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.109
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.108
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.108
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.105
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.104
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.104
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.103
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.103
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.102
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.101
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.100
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.099
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.099
|
Yeast |
|
|
peptidyl lysine monomethylation
|
GO:0018026 |
4 |
0.099
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.099
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.098
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.098
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.097
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.097
|
Mouse Rat Fly |
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.097
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.097
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.097
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.097
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.097
|
Mouse |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.096
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.096
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.096
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.095
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.095
|
Mouse |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.095
|
|
|
|
regulation of oocyte maturation
|
GO:1900193 |
1 |
0.094
|
Worm |
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.093
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.093
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.093
|
Human Mouse |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.092
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.092
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.092
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.092
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.090
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.090
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.088
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.087
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.087
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.086
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.086
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.085
|
|
|
|
memory
|
GO:0007613 |
3 |
0.085
|
Fly |
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.085
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.084
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.083
|
Mouse |
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.083
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.082
|
Mouse |
|
|
endoplasmic reticulum to cytosol transport
|
GO:1903513 |
13 |
0.082
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.081
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.081
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.081
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.080
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.080
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.080
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.080
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.079
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.078
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.078
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.078
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.078
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.078
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.077
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.077
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.076
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.076
|
Mouse Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.076
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.075
|
Worm Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.075
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.075
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.075
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.074
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.074
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.074
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.074
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.074
|
Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.073
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.073
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.073
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.073
|
Worm Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.073
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.072
|
Rat |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.072
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.071
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.071
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.070
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.070
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.070
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.070
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.070
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.070
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.069
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.069
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.068
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.068
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.068
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.067
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.067
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.066
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.066
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.066
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.066
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.065
|
|
|
|
positive regulation of transcription during mitosis
|
GO:0045897 |
2 |
0.065
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.064
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.064
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.064
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.064
|
Human Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.063
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.063
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.062
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.062
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.062
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.062
|
|
|
|
negative regulation of nfat protein import into nucleus
|
GO:0051534 |
2 |
0.062
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.062
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.062
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.062
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.062
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.062
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
15 |
0.061
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.061
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.061
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.061
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.060
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.060
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.060
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.060
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.060
|
Fly |
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.060
|
|
|
|
disruption by host of symbiont cells
|
GO:0051852 |
2 |
0.059
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.059
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.058
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.058
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.058
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.058
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.058
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.058
|
Mouse Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.058
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.057
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.057
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.057
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.057
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.057
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.057
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.057
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.057
|
Mouse |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.057
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.056
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.056
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.056
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.055
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.055
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.055
|
Worm |
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.055
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.054
|
Mouse |
|
|
viral process
|
GO:0016032 |
146 |
0.054
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.053
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.053
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.053
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.053
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.053
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.053
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.053
|
Rat |
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.053
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.052
|
|
|
|
regulation of transcription during mitosis
|
GO:0045896 |
2 |
0.052
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.052
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.052
|
Human |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.051
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.051
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.051
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.051
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.050
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.050
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.050
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.050
|
Mouse |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.050
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.050
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.050
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.049
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.049
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.049
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.049
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.048
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.048
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.047
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.047
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.047
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.046
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.046
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.046
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.046
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.046
|
Worm |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.046
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.045
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.045
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.045
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.045
|
Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.044
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.044
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.044
|
|
|
|
growth
|
GO:0040007 |
202 |
0.044
|
Yeast |
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.044
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.043
|
Fly |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.043
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.043
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.043
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.043
|
Human Mouse |
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.043
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.043
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.043
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.042
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.042
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.042
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.042
|
Fly |
|
|
sarcoplasmic reticulum calcium ion transport
|
GO:0070296 |
13 |
0.042
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.042
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.042
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.042
|
Human Mouse |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.042
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.041
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.041
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.041
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.041
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.041
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
14 |
0.041
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.041
|
Mouse Worm Fly |
|
|
lipid transport
|
GO:0006869 |
90 |
0.041
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.040
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.040
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.040
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.040
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.040
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.039
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.039
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.039
|
|
|
|
regulation of cardiac muscle contraction by calcium ion signaling
|
GO:0010882 |
3 |
0.039
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.039
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.039
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.039
|
Human |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.039
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.038
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.038
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.038
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.038
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.038
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.038
|
Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.037
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.037
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.037
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.037
|
Worm Fly |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.037
|
Yeast |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.037
|
Human Mouse |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.036
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.036
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.036
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.036
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.036
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.036
|
|
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
20 |
0.036
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.036
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.036
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.036
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.036
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.036
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.036
|
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.036
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.036
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.035
|
Human Mouse |
|
|
dna repair
|
GO:0006281 |
198 |
0.035
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.035
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.035
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.035
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.035
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.035
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.035
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.034
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.034
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.034
|
Mouse |
|
|
g protein coupled receptor signaling pathway involved in heart process
|
GO:0086103 |
1 |
0.034
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
9 |
0.034
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.033
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.033
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.033
|
|
|
|
negative regulation of non canonical wnt signaling pathway
|
GO:2000051 |
1 |
0.033
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.033
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.033
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.033
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.033
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.033
|
|
