Homo sapiens

78 known processes

PRKCB

protein kinase C, beta

(Aliases: PKCB,PKC-beta,MGC41878,PRKCB1,PRKCB2)

PRKCB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukotriene metabolic process GO:0006691 10 0.979
negative regulation of muscle contraction GO:0045932 3 0.973
cellular ketone metabolic process GO:0042180 80 0.827
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.768
cellular amino acid metabolic process GO:0006520 116 0.683
cellular macromolecular complex assembly GO:0034622 324 0.642
cellular glucuronidation GO:0052695 16 0.635
Human
cellular defense response GO:0006968 2 0.618
cellular metal ion homeostasis GO:0006875 146 0.533
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.532
positive regulation of glial cell proliferation GO:0060252 2 0.528
Human
regulation of cellular amine metabolic process GO:0033238 11 0.515
regulation of cell differentiation GO:0045595 393 0.513
Human
cellular protein complex assembly GO:0043623 188 0.497
regulation of cellular component biogenesis GO:0044087 281 0.493
Human
monocarboxylic acid metabolic process GO:0032787 185 0.490
Human
cellular amine metabolic process GO:0044106 41 0.465
amine metabolic process GO:0009308 44 0.461
growth GO:0040007 202 0.454
regulation of locomotion GO:0040012 329 0.433
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.428
Mouse
peptidyl tyrosine modification GO:0018212 170 0.420
regulation of protein serine threonine kinase activity GO:0071900 179 0.417
cytoplasmic transport GO:0016482 379 0.416
regulation of peptidase activity GO:0052547 180 0.386
oxidation reduction process GO:0055114 396 0.382
negative regulation of apoptotic process GO:0043066 316 0.382
Human
positive regulation of map kinase activity GO:0043406 80 0.369
positive regulation of protein kinase activity GO:0045860 190 0.367
protein autophosphorylation GO:0046777 123 0.360
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.348
regulation of cell motility GO:2000145 299 0.323
Human
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.322
Human
positive regulation of apoptotic process GO:0043065 246 0.313
positive regulation of cellular amine metabolic process GO:0033240 7 0.310
regulation of glial cell proliferation GO:0060251 4 0.307
Human
divalent inorganic cation homeostasis GO:0072507 136 0.305
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.298
regulation of protein kinase activity GO:0045859 289 0.294
regulation of cell cell adhesion GO:0022407 57 0.281
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.275
metal ion homeostasis GO:0055065 169 0.275
Mouse
negative regulation of cell death GO:0060548 345 0.271
Human
immune response GO:0006955 307 0.270
Mouse
lymphocyte proliferation GO:0046651 70 0.262
system process GO:0003008 349 0.261
Fly
positive regulation of apoptotic signaling pathway GO:2001235 70 0.254
glucan biosynthetic process GO:0009250 16 0.251
superoxide metabolic process GO:0006801 20 0.250
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.248
peptidyl tyrosine phosphorylation GO:0018108 170 0.248
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.244
Human Mouse
regulation of mapk cascade GO:0043408 262 0.241
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.239
Human Mouse
cellular polysaccharide biosynthetic process GO:0033692 21 0.234
regulation of map kinase activity GO:0043405 108 0.234
negative regulation of phosphate metabolic process GO:0045936 267 0.232
cellular response to endogenous stimulus GO:0071495 336 0.232
cell development GO:0048468 328 0.232
Human
epithelium migration GO:0090132 119 0.224
Human
regulation of cell migration GO:0030334 289 0.220
Human
positive regulation of cell death GO:0010942 263 0.217
single organism carbohydrate metabolic process GO:0044723 193 0.215
Human
calcium ion transport GO:0006816 147 0.214
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.213
superoxide anion generation GO:0042554 11 0.203
taxis GO:0042330 157 0.201
determination of adult lifespan GO:0008340 2 0.201
positive regulation of programmed cell death GO:0043068 249 0.195
cellular calcium ion homeostasis GO:0006874 117 0.193
Mouse
negative regulation of t cell apoptotic process GO:0070233 4 0.193
regulation of protein processing GO:0070613 150 0.192
small gtpase mediated signal transduction GO:0007264 78 0.188
regulation of ion homeostasis GO:2000021 73 0.188
positive regulation of catabolic process GO:0009896 310 0.186
membrane organization GO:0061024 292 0.185
ion homeostasis GO:0050801 230 0.184
Mouse
negative regulation of kinase activity GO:0033673 106 0.181
multicellular organismal aging GO:0010259 3 0.180
regulation of cell adhesion GO:0030155 166 0.176
Human
regulation of ion transport GO:0043269 189 0.172
response to cytokine GO:0034097 232 0.171
Human
immune system development GO:0002520 195 0.165
nitrogen compound transport GO:0071705 191 0.164
cell morphogenesis GO:0000902 296 0.164
regulation of carbohydrate metabolic process GO:0006109 54 0.164
Human
negative regulation of protein modification process GO:0031400 200 0.162
reactive oxygen species metabolic process GO:0072593 75 0.162
negative regulation of cellular protein metabolic process GO:0032269 353 0.158
positive regulation of developmental process GO:0051094 314 0.158
Human Mouse
dephosphorylation GO:0016311 209 0.157
neutrophil mediated killing of bacterium GO:0070944 1 0.156
mapk cascade GO:0000165 288 0.156
regulation of cellular glucuronidation GO:2001029 5 0.155
Human
generation of neurons GO:0048699 152 0.155
Human
chemical homeostasis GO:0048878 306 0.154
Mouse
regulation of transferase activity GO:0051338 355 0.154
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.154
exocytosis GO:0006887 71 0.153
regulation of glucan biosynthetic process GO:0010962 14 0.152
regulation of nervous system development GO:0051960 88 0.151
Human
divalent metal ion transport GO:0070838 152 0.151
Mouse
cell chemotaxis GO:0060326 112 0.151
hematopoietic or lymphoid organ development GO:0048534 186 0.151
regulation of transmembrane transport GO:0034762 139 0.149
regulation of neurogenesis GO:0050767 82 0.147
Human
regulation of cellular component movement GO:0051270 334 0.146
Human
cellular carbohydrate metabolic process GO:0044262 84 0.143
Human
divalent inorganic cation transport GO:0072511 158 0.142
Mouse
regulation of kinase activity GO:0043549 314 0.142
negative regulation of multicellular organismal process GO:0051241 317 0.140
negative regulation of transport GO:0051051 176 0.137
Mouse
regulation of proteolysis GO:0030162 293 0.137
negative regulation of intracellular signal transduction GO:1902532 183 0.136
response to external biotic stimulus GO:0043207 261 0.135
Human
calcium ion homeostasis GO:0055074 122 0.133
Mouse
peptidyl serine phosphorylation GO:0018105 101 0.133
Human Worm
post embryonic development GO:0009791 2 0.131
positive regulation of neuron differentiation GO:0045666 40 0.129
peptidyl threonine phosphorylation GO:0018107 41 0.129
uronic acid metabolic process GO:0006063 16 0.129
Human
organophosphate catabolic process GO:0046434 430 0.129
positive regulation of cell proliferation GO:0008284 301 0.129
Human
positive regulation of kinase activity GO:0033674 204 0.129
oogenesis GO:0048477 2 0.128
lymphocyte activation GO:0046649 133 0.127
Mouse
regulation of cell projection organization GO:0031344 107 0.127
positive regulation of immune system process GO:0002684 283 0.127
Human Mouse
cell adhesion GO:0007155 325 0.126
Human
biological adhesion GO:0022610 331 0.126
Human
negative regulation of protein metabolic process GO:0051248 391 0.125
vesicle mediated transport GO:0016192 371 0.125
Fly
regulation of protein polymerization GO:0032271 63 0.124
cytosolic calcium ion homeostasis GO:0051480 89 0.122
monosaccharide metabolic process GO:0005996 74 0.122
Human
regulation of cell activation GO:0050865 125 0.119
Human
muscle system process GO:0003012 81 0.119
cellular lipid metabolic process GO:0044255 303 0.118
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.117
protein catabolic process GO:0030163 325 0.116
modification dependent macromolecule catabolic process GO:0043632 212 0.116
positive regulation of cell differentiation GO:0045597 211 0.115
Human
positive regulation of glycogen biosynthetic process GO:0045725 10 0.115
glycogen metabolic process GO:0005977 22 0.114
organelle assembly GO:0070925 176 0.113
regulation of glucose import GO:0046324 21 0.113
leukocyte activation GO:0045321 164 0.113
Mouse
negative regulation of programmed cell death GO:0043069 321 0.110
Human
muscle contraction GO:0006936 73 0.110
positive regulation of cellular component movement GO:0051272 181 0.107
Human
neurotransmitter secretion GO:0007269 4 0.107
chemotaxis GO:0006935 157 0.107
response to fungus GO:0009620 4 0.107
cardiovascular system development GO:0072358 262 0.105
Human Mouse
positive regulation of gliogenesis GO:0014015 4 0.103
Human
actin filament based process GO:0030029 224 0.103
cation homeostasis GO:0055080 189 0.103
Mouse
nervous system development GO:0007399 293 0.102
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.102
ribonucleotide catabolic process GO:0009261 405 0.102
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.102
Human
regulation of protein localization GO:0032880 296 0.101
organic hydroxy compound metabolic process GO:1901615 147 0.099
lipid metabolic process GO:0006629 381 0.099
regulation of vesicle mediated transport GO:0060627 130 0.099
single organism membrane organization GO:0044802 268 0.099
regulation of cytoskeleton organization GO:0051493 177 0.098
regulation of protein catabolic process GO:0042176 155 0.098
negative regulation of protein complex assembly GO:0031333 43 0.098
positive regulation of cell development GO:0010720 92 0.098
Human
negative regulation of protein phosphorylation GO:0001933 140 0.097
cellular component morphogenesis GO:0032989 314 0.097
sequestering of metal ion GO:0051238 24 0.096
negative regulation of catalytic activity GO:0043086 335 0.096
small molecule catabolic process GO:0044282 92 0.094
negative regulation of proteolysis GO:0045861 132 0.094
regulation of intracellular transport GO:0032386 195 0.094
anion transport GO:0006820 161 0.093
cellular homeostasis GO:0019725 196 0.093
Mouse
purine containing compound catabolic process GO:0072523 411 0.092
plasma membrane organization GO:0007009 115 0.091
sequestering of calcium ion GO:0051208 17 0.090
negative regulation of map kinase activity GO:0043407 27 0.090
apoptotic signaling pathway GO:0097190 268 0.089
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.089
protein maturation GO:0051604 233 0.088
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.088
Human Mouse
protein processing GO:0016485 226 0.087
regulation of cell development GO:0060284 161 0.087
Human
regulation of protein localization to plasma membrane GO:1903076 40 0.087
post embryonic organ development GO:0048569 1 0.087
positive regulation of cellular component organization GO:0051130 376 0.086
activation of protein kinase activity GO:0032147 90 0.086
regulation of glycogen metabolic process GO:0070873 15 0.085
regulation of muscle contraction GO:0006937 45 0.085
protein dephosphorylation GO:0006470 81 0.084
ion transmembrane transport GO:0034220 338 0.084
Mouse
secretion GO:0046903 254 0.084
leukocyte apoptotic process GO:0071887 31 0.083
response to oxidative stress GO:0006979 121 0.083
regulation of transporter activity GO:0032409 82 0.083
positive regulation of transferase activity GO:0051347 227 0.082
phospholipid metabolic process GO:0006644 99 0.082
carbohydrate metabolic process GO:0005975 207 0.081
Human
behavior GO:0007610 112 0.081
regulation of ion transmembrane transport GO:0034765 132 0.081
regulation of cellular ketone metabolic process GO:0010565 50 0.081
Human
transmembrane transport GO:0055085 399 0.080
Mouse
negative regulation of transferase activity GO:0051348 124 0.080
tissue migration GO:0090130 119 0.080
Human
cellular polysaccharide metabolic process GO:0044264 27 0.079
negative regulation of protein processing GO:0010955 142 0.079
regulation of epithelial cell proliferation GO:0050678 113 0.079
Human
response to radiation GO:0009314 151 0.078
Fly
regulation of immune response GO:0050776 201 0.076
Human Mouse
regulation of epithelial cell migration GO:0010632 93 0.075
Human
negative regulation of platelet aggregation GO:0090331 3 0.075
positive regulation of endothelial cell migration GO:0010595 39 0.075
Human
glycosyl compound catabolic process GO:1901658 413 0.075
cellular carbohydrate biosynthetic process GO:0034637 21 0.075
azole transport GO:0045117 4 0.074
positive regulation of nucleotide catabolic process GO:0030813 185 0.074
single organism cell adhesion GO:0098602 179 0.074
Human
multicellular organismal macromolecule metabolic process GO:0044259 29 0.074
regulation of muscle system process GO:0090257 53 0.073
endocytosis GO:0006897 159 0.073
Fly
positive regulation of carbohydrate metabolic process GO:0045913 21 0.073
Human
phototransduction visible light GO:0007603 2 0.073
Fly
cell cell junction organization GO:0045216 69 0.073
Human
positive regulation of ras gtpase activity GO:0032320 117 0.072
immune effector process GO:0002252 159 0.072
negative regulation of hydrolase activity GO:0051346 182 0.072
positive regulation of nucleoside metabolic process GO:0045979 186 0.072
immune response activating signal transduction GO:0002757 90 0.072
Human Mouse
mitotic cell cycle GO:0000278 326 0.071
Human
signal transduction by phosphorylation GO:0023014 297 0.071
mitotic cell cycle process GO:1903047 286 0.071
establishment of protein localization to organelle GO:0072594 172 0.071
regulation of cytoplasmic transport GO:1903649 149 0.071
response to light stimulus GO:0009416 87 0.071
Fly
detection of stimulus GO:0051606 85 0.070
Fly
negative regulation of cellular component organization GO:0051129 235 0.070
cellular cation homeostasis GO:0030003 163 0.070
Mouse
regulation of glycogen biosynthetic process GO:0005979 14 0.069
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.069
cellular ion homeostasis GO:0006873 168 0.069
Mouse
leukocyte chemotaxis GO:0030595 76 0.068
neurological system process GO:0050877 163 0.068
Fly
carbohydrate transport GO:0008643 37 0.068
Mouse
unsaturated fatty acid metabolic process GO:0033559 37 0.068
purine ribonucleotide catabolic process GO:0009154 404 0.068
negative regulation of protein kinase activity GO:0006469 98 0.068
regulation of platelet aggregation GO:0090330 4 0.067
Human
purine nucleoside catabolic process GO:0006152 398 0.067
positive regulation of endothelial cell proliferation GO:0001938 37 0.067
Human
regulation of body fluid levels GO:0050878 99 0.067
Human
defense response GO:0006952 315 0.066
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.066
regulation of anatomical structure morphogenesis GO:0022603 286 0.066
Human Mouse
sphingolipid metabolic process GO:0006665 38 0.066
reactive nitrogen species metabolic process GO:2001057 3 0.066
protein ubiquitination GO:0016567 314 0.066
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.066
regulation of metal ion transport GO:0010959 120 0.066
neutrophil mediated immunity GO:0002446 4 0.065
cell projection organization GO:0030030 252 0.065
anatomical structure formation involved in morphogenesis GO:0048646 284 0.065
Human Mouse
regulation of dephosphorylation GO:0035303 96 0.065
response to drug GO:0042493 81 0.065
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.065
blood coagulation GO:0007596 76 0.065
Human
protein modification by small protein conjugation GO:0032446 342 0.065
glycogen biosynthetic process GO:0005978 16 0.064
regulation of wound healing GO:0061041 56 0.064
Human
fatty acid derivative metabolic process GO:1901568 35 0.064
regulation of system process GO:0044057 101 0.064
female gamete generation GO:0007292 2 0.063
response to nitrogen compound GO:1901698 184 0.062
polysaccharide biosynthetic process GO:0000271 27 0.062
peroxisome degradation GO:0030242 1 0.062
reactive oxygen species biosynthetic process GO:1903409 4 0.061
innate immune response GO:0045087 178 0.061
establishment of protein localization to membrane GO:0090150 121 0.061
platelet activation GO:0030168 44 0.061
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.061
response to growth factor GO:0070848 205 0.061
Mouse
modification dependent protein catabolic process GO:0019941 209 0.061
positive regulation of leukocyte proliferation GO:0070665 48 0.061
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.060
Human Mouse
secretion by cell GO:0032940 226 0.060
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.060
neuron differentiation GO:0030182 138 0.060
myeloid leukocyte migration GO:0097529 62 0.059
positive regulation of phosphorylation GO:0042327 394 0.059
organic anion transport GO:0015711 103 0.059
neuron projection development GO:0031175 106 0.058
negative regulation of phosphorylation GO:0042326 174 0.058
activation of immune response GO:0002253 114 0.058
Human Mouse
carboxylic acid catabolic process GO:0046395 71 0.058
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.057
negative regulation of organelle organization GO:0010639 126 0.057
positive regulation of transport GO:0051050 336 0.057
single organism cellular localization GO:1902580 332 0.057
cell projection assembly GO:0030031 126 0.057
cellular protein catabolic process GO:0044257 261 0.056
cellular response to organonitrogen compound GO:0071417 124 0.056
mitotic cell cycle phase transition GO:0044772 162 0.056
regulation of lipid transport GO:0032368 44 0.056
skeletal system development GO:0001501 79 0.056
regulation of cell morphogenesis GO:0022604 153 0.055
generation of precursor metabolites and energy GO:0006091 68 0.054
protein localization to organelle GO:0033365 280 0.054
rhodopsin mediated signaling pathway GO:0016056 1 0.054
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.054
Mouse
single organismal cell cell adhesion GO:0016337 148 0.053
Human
regulation of hemostasis GO:1900046 42 0.053
Human
negative regulation of catabolic process GO:0009895 104 0.053
regulation of coagulation GO:0050818 44 0.053
Human
b cell receptor signaling pathway GO:0050853 18 0.053
Human Mouse
cytosolic calcium ion transport GO:0060401 48 0.053
purine ribonucleoside catabolic process GO:0046130 398 0.053
cellular response to biotic stimulus GO:0071216 71 0.052
Human
sensory perception of smell GO:0007608 2 0.052
cell cell signaling GO:0007267 155 0.052
positive regulation of superoxide anion generation GO:0032930 4 0.052
response to oxygen containing compound GO:1901700 369 0.052
Human Mouse Fly
lipid oxidation GO:0034440 33 0.052
neurogenesis GO:0022008 169 0.051
Human
response to organic cyclic compound GO:0014070 204 0.051
response to biotic stimulus GO:0009607 276 0.051
Human
positive regulation of cell motility GO:2000147 177 0.051
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.051
regulation of peptidyl serine phosphorylation GO:0033135 50 0.051
cellular glucan metabolic process GO:0006073 22 0.051
response to acid chemical GO:0001101 66 0.050
hemopoiesis GO:0030097 180 0.050
synaptic vesicle exocytosis GO:0016079 3 0.050
epithelial cell proliferation GO:0050673 128 0.050
Human
regulation of anatomical structure size GO:0090066 101 0.049
epithelial cell migration GO:0010631 119 0.049
Human
platelet aggregation GO:0070527 32 0.049
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.049
response to other organism GO:0051707 261 0.049
Human
aspartate transport GO:0015810 5 0.049
covalent chromatin modification GO:0016569 254 0.049
protein localization to nucleus GO:0034504 136 0.049
cell fate determination GO:0001709 3 0.048
circulatory system development GO:0072359 262 0.048
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.048
cellular response to peptide hormone stimulus GO:0071375 56 0.048
nucleoside triphosphate catabolic process GO:0009143 394 0.048
jnk cascade GO:0007254 80 0.048
carbohydrate biosynthetic process GO:0016051 42 0.048
negative regulation of protein maturation GO:1903318 142 0.047
negative regulation of endopeptidase activity GO:0010951 84 0.047
glial cell apoptotic process GO:0034349 7 0.047
Human
regulation of behavior GO:0050795 82 0.046
maintenance of location GO:0051235 112 0.046
positive regulation of cellular component biogenesis GO:0044089 158 0.046
cellular response to external stimulus GO:0071496 111 0.046
leukocyte proliferation GO:0070661 74 0.046
regulation of sequestering of calcium ion GO:0051282 41 0.046
memory GO:0007613 3 0.046
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.046
regulation of endopeptidase activity GO:0052548 170 0.045
regulation of blood vessel endothelial cell migration GO:0043535 30 0.045
Human
regulation of endothelial cell proliferation GO:0001936 56 0.045
Human
response to organonitrogen compound GO:0010243 156 0.045
alcohol metabolic process GO:0006066 114 0.045
organelle localization GO:0051640 84 0.045
positive regulation of cellular catabolic process GO:0031331 284 0.044
cellular response to oxygen containing compound GO:1901701 276 0.044
Human Mouse
endothelial cell migration GO:0043542 86 0.044
Human
organophosphate ester transport GO:0015748 32 0.044
mrna catabolic process GO:0006402 56 0.044
regulation of reactive oxygen species metabolic process GO:2000377 41 0.044
ras protein signal transduction GO:0007265 73 0.044
ribonucleoside catabolic process GO:0042454 406 0.044
positive regulation of blood pressure GO:0045777 3 0.044
mononuclear cell proliferation GO:0032943 71 0.043
regulation of homeostatic process GO:0032844 121 0.043
regulation of defense response GO:0031347 154 0.043
actin polymerization or depolymerization GO:0008154 56 0.043
fatty acid metabolic process GO:0006631 115 0.042
blood vessel endothelial cell migration GO:0043534 42 0.042
Human
protein import into nucleus GO:0006606 104 0.042
negative regulation of fatty acid oxidation GO:0046322 1 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
muscle structure development GO:0061061 98 0.042
signal release GO:0023061 70 0.042
regulation of secretion by cell GO:1903530 177 0.042
positive regulation of ion transport GO:0043270 87 0.042
positive regulation of oxidoreductase activity GO:0051353 26 0.042
regulation of cellular response to insulin stimulus GO:1900076 17 0.042
multicellular organismal metabolic process GO:0044236 34 0.042
leukocyte differentiation GO:0002521 98 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
ribonucleoprotein complex biogenesis GO:0022613 116 0.041
dicarboxylic acid transport GO:0006835 13 0.041
negative regulation of protein ubiquitination GO:0031397 35 0.041
anion transmembrane transport GO:0098656 76 0.041
positive regulation of cell migration GO:0030335 172 0.041
Human
regulation of response to external stimulus GO:0032101 222 0.040
Human Fly
regulation of actin filament based process GO:0032970 141 0.040
regulation of cell growth GO:0001558 135 0.040
energy derivation by oxidation of organic compounds GO:0015980 43 0.040
regulation of protein complex assembly GO:0043254 147 0.040
regulation of neuron differentiation GO:0045664 70 0.040
antigen receptor mediated signaling pathway GO:0050851 38 0.040
Human Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.040
cell activation GO:0001775 213 0.040
Human Mouse
organ morphogenesis GO:0009887 147 0.040
b cell activation GO:0042113 33 0.040
Mouse
positive regulation of nucleotide metabolic process GO:0045981 230 0.039
polysaccharide metabolic process GO:0005976 33 0.039
response to wounding GO:0009611 168 0.039
Human
intrinsic apoptotic signaling pathway GO:0097193 127 0.039
response to inorganic substance GO:0010035 127 0.039
establishment of organelle localization GO:0051656 59 0.039
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.039
neuron development GO:0048666 113 0.039
lipid biosynthetic process GO:0008610 177 0.039
endothelial cell proliferation GO:0001935 65 0.039
Human
protein import GO:0017038 130 0.039
positive regulation of neurogenesis GO:0050769 49 0.038
Human
regulation of gtp catabolic process GO:0033124 180 0.038
leukocyte migration GO:0050900 107 0.038
lipid modification GO:0030258 84 0.038
neutrophil mediated cytotoxicity GO:0070942 1 0.038
cellular response to abiotic stimulus GO:0071214 117 0.038
Fly
cellular macromolecule catabolic process GO:0044265 380 0.038
protein polymerization GO:0051258 71 0.038
mitochondrion organization GO:0007005 156 0.037
cellular lipid catabolic process GO:0044242 65 0.037
icosanoid metabolic process GO:0006690 35 0.037
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.037
cellular response to dna damage stimulus GO:0006974 379 0.037
regulation of cell cycle GO:0051726 393 0.037
Human
regulation of insulin receptor signaling pathway GO:0046626 13 0.037
pericardium development GO:0060039 2 0.037
proteasomal protein catabolic process GO:0010498 176 0.037
cellular response to lipid GO:0071396 127 0.037
Human
mrna metabolic process GO:0016071 175 0.037
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.037
Human
positive regulation of gtpase activity GO:0043547 166 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
peptidyl threonine modification GO:0018210 45 0.036
response to transforming growth factor beta GO:0071559 94 0.036
dna repair GO:0006281 198 0.036
ethanolamine containing compound metabolic process GO:0042439 26 0.036
actin filament based movement GO:0030048 17 0.036
purine nucleotide catabolic process GO:0006195 405 0.035
negative regulation of locomotion GO:0040013 118 0.035
response to peptide GO:1901652 65 0.035
protein targeting to nucleus GO:0044744 104 0.035
regulation of secretion GO:0051046 194 0.035
positive regulation of b cell receptor signaling pathway GO:0050861 1 0.035
Human Mouse
liposaccharide metabolic process GO:1903509 27 0.035
cell cycle g1 s phase transition GO:0044843 80 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
regulation of protein maturation GO:1903317 150 0.035
negative regulation of lipid transport GO:0032369 18 0.035
rna processing GO:0006396 255 0.034
histone threonine phosphorylation GO:0035405 7 0.034
ribonucleoprotein complex subunit organization GO:0071826 81 0.034
response to lipid GO:0033993 206 0.034
Human
protein targeting GO:0006605 187 0.034
cation transport GO:0006812 331 0.033
Mouse
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.033
negative regulation of protein catabolic process GO:0042177 59 0.033
sensory perception of light stimulus GO:0050953 35 0.033
Fly
negative regulation of blood coagulation GO:0030195 22 0.033
respiratory burst involved in defense response GO:0002679 2 0.033
neuromuscular junction development GO:0007528 3 0.033
inflammatory response GO:0006954 79 0.033
leukocyte mediated immunity GO:0002443 59 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.032
Mouse
regulation of growth GO:0040008 165 0.032
calcium ion transport into cytosol GO:0060402 48 0.032
nucleoside catabolic process GO:0009164 408 0.032
t cell homeostasis GO:0043029 3 0.032
vasculature development GO:0001944 181 0.032
Human Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.032
gtp catabolic process GO:0006184 237 0.032
positive regulation of epithelial cell proliferation GO:0050679 65 0.031
Human
regulation of nucleoside metabolic process GO:0009118 209 0.031
carboxylic acid transport GO:0046942 63 0.031
cell junction organization GO:0034330 79 0.031
Human
negative regulation of lipid metabolic process GO:0045833 38 0.031
defense response to fungus GO:0050832 4 0.031

PRKCB disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.793
primary immunodeficiency disease DOID:612 36 0.769
hematopoietic system disease DOID:74 100 0.387
b cell deficiency DOID:2115 17 0.363
blood protein disease DOID:620 16 0.214
agammaglobulinemia DOID:2583 16 0.089
common variable immunodeficiency DOID:12177 10 0.089