Homo sapiens

145 known processes

PRKCI

protein kinase C, iota

(Aliases: PKCI,MGC26534,DXS1179E,nPKC-iota)

PRKCI biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric stem cell division GO:0098722 1 0.918
asymmetric neuroblast division GO:0055059 1 0.883
somatic stem cell division GO:0048103 1 0.880
neuronal stem cell division GO:0036445 1 0.858
neuroblast division GO:0055057 1 0.834
neuroblast proliferation GO:0007405 4 0.758
Zebrafish
post embryonic development GO:0009791 2 0.725
Worm
lipid metabolic process GO:0006629 381 0.722
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.699
cell fate determination GO:0001709 3 0.653
regulation of transferase activity GO:0051338 355 0.634
Human
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.623
regulation of kinase activity GO:0043549 314 0.608
Human
oocyte differentiation GO:0009994 2 0.598
tube morphogenesis GO:0035239 95 0.584
Zebrafish
specification of axis polarity GO:0065001 1 0.571
vesicle mediated transport GO:0016192 371 0.555
Worm
embryonic morphogenesis GO:0048598 85 0.546
Zebrafish
stem cell division GO:0017145 2 0.524
segmentation GO:0035282 4 0.492
morphogenesis of embryonic epithelium GO:0016331 4 0.480
Zebrafish
anterior posterior axis specification GO:0009948 2 0.464
negative regulation of protein metabolic process GO:0051248 391 0.462
Human
organelle localization GO:0051640 84 0.454
Zebrafish
anterior posterior axis specification embryo GO:0008595 2 0.441
digestive tract development GO:0048565 75 0.419
Zebrafish
oocyte development GO:0048599 1 0.407
nervous system development GO:0007399 293 0.388
collateral sprouting GO:0048668 2 0.380
regulation of actin cytoskeleton organization GO:0032956 116 0.379
oogenesis GO:0048477 2 0.376
neural tube formation GO:0001841 3 0.373
Zebrafish
regulation of cellular component size GO:0032535 82 0.360
cellular amino acid metabolic process GO:0006520 116 0.355
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.332
Zebrafish Mouse
growth GO:0040007 202 0.330
Human
blastoderm segmentation GO:0007350 2 0.322
regulation of cellular component movement GO:0051270 334 0.320
Human
establishment or maintenance of neuroblast polarity GO:0045196 1 0.320
regulation of protein kinase activity GO:0045859 289 0.312
Human
establishment of neuroblast polarity GO:0045200 1 0.311
female gamete generation GO:0007292 2 0.301
nucleoside triphosphate metabolic process GO:0009141 422 0.293
epithelium development GO:0060429 227 0.282
Zebrafish
cell junction maintenance GO:0034331 4 0.282
Zebrafish
endocytosis GO:0006897 159 0.275
Worm
regulation of actin filament polymerization GO:0030833 50 0.269
positive regulation of phosphorylation GO:0042327 394 0.258
Human
cell projection organization GO:0030030 252 0.243
microtubule cytoskeleton organization GO:0000226 176 0.242
Zebrafish
regulation of cellular component biogenesis GO:0044087 281 0.235
Human
non canonical wnt signaling pathway GO:0035567 14 0.234
negative regulation of catalytic activity GO:0043086 335 0.233
Human
regulation of protein polymerization GO:0032271 63 0.232
positive regulation of developmental process GO:0051094 314 0.231
purine nucleoside triphosphate metabolic process GO:0009144 412 0.230
regulation of actin filament based process GO:0032970 141 0.230
cellular component morphogenesis GO:0032989 314 0.225
regulation of cell projection organization GO:0031344 107 0.224
cellular amine metabolic process GO:0044106 41 0.222
Human
negative regulation of protein modification process GO:0031400 200 0.222
Human
establishment of organelle localization GO:0051656 59 0.219
Zebrafish
peptidyl serine phosphorylation GO:0018105 101 0.219
Human Worm
actin filament organization GO:0007015 128 0.217
Yeast Mouse
lipid catabolic process GO:0016042 84 0.212
Human
cellular ketone metabolic process GO:0042180 80 0.212
Human
tissue morphogenesis GO:0048729 96 0.211
Zebrafish
cellular lipid metabolic process GO:0044255 303 0.205
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.204
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.203
regulation of mapk cascade GO:0043408 262 0.191
Human
generation of neurons GO:0048699 152 0.183
cell morphogenesis GO:0000902 296 0.182
regulation of cell differentiation GO:0045595 393 0.182
embryonic epithelial tube formation GO:0001838 4 0.174
Zebrafish
dephosphorylation GO:0016311 209 0.173
Human
tripartite regional subdivision GO:0007351 2 0.173
tube development GO:0035295 125 0.172
Zebrafish
peptidyl serine modification GO:0018209 106 0.171
Human Worm
establishment of cell polarity GO:0030010 22 0.171
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.170
Human
regulation of cell morphogenesis GO:0022604 153 0.168
signal transduction by phosphorylation GO:0023014 297 0.165
Human
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.160
Zebrafish
regulation of locomotion GO:0040012 329 0.158
Human
wound healing GO:0042060 115 0.155
regulation of cell growth GO:0001558 135 0.155
Human
regulation of cytoskeleton organization GO:0051493 177 0.154
axis elongation GO:0003401 4 0.148
regulation of cellular amine metabolic process GO:0033238 11 0.148
Human
actin filament based process GO:0030029 224 0.141
Yeast Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.138
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.135
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.134
cell projection assembly GO:0030031 126 0.134
cell fate commitment GO:0045165 27 0.133
regulation of cell migration GO:0030334 289 0.133
Human
mitotic cell cycle process GO:1903047 286 0.132
Human Zebrafish
positive regulation of cellular component biogenesis GO:0044089 158 0.131
microtubule based process GO:0007017 210 0.128
Zebrafish
spinal cord development GO:0021510 4 0.127
morphogenesis of a polarized epithelium GO:0001738 3 0.124
Zebrafish
mapk cascade GO:0000165 288 0.123
Human
epidermis morphogenesis GO:0048730 3 0.123
cell development GO:0048468 328 0.120
cell division GO:0051301 168 0.119
Worm
actin cytoskeleton organization GO:0030036 207 0.118
Yeast Mouse
cytokinesis GO:0000910 96 0.117
establishment of planar polarity GO:0001736 3 0.113
negative regulation of phosphorylation GO:0042326 174 0.111
Human
positive regulation of protein kinase activity GO:0045860 190 0.110
Human
regionalization GO:0003002 29 0.110
positive regulation of cellular component organization GO:0051130 376 0.108
cell adhesion GO:0007155 325 0.107
digestive tract morphogenesis GO:0048546 56 0.107
Zebrafish
positive regulation of mapk cascade GO:0043410 190 0.106
Human
neurogenesis GO:0022008 169 0.105
neurological system process GO:0050877 163 0.105
negative regulation of cellular component organization GO:0051129 235 0.104
Human
receptor mediated endocytosis GO:0006898 84 0.104
Worm
digestive system development GO:0055123 75 0.103
Zebrafish
regulation of interleukin 5 secretion GO:2000662 2 0.102
system process GO:0003008 349 0.098
positive regulation of cellular amine metabolic process GO:0033240 7 0.096
Human
amine metabolic process GO:0009308 44 0.095
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.094
Human
fatty acid metabolic process GO:0006631 115 0.093
Human
interleukin 5 secretion GO:0072603 2 0.091
positive regulation of kinase activity GO:0033674 204 0.090
Human
hindbrain development GO:0030902 3 0.089
Zebrafish
negative regulation of cellular protein metabolic process GO:0032269 353 0.089
Human
regulation of wound healing GO:0061041 56 0.088
positive regulation of organelle organization GO:0010638 195 0.087
cytoplasmic transport GO:0016482 379 0.087
Human
ribonucleotide biosynthetic process GO:0009260 81 0.086
brain development GO:0007420 97 0.084
Zebrafish
establishment of protein localization to membrane GO:0090150 121 0.084
Human Mouse
protein polymerization GO:0051258 71 0.084
regulation of protein complex assembly GO:0043254 147 0.083
Human
cytokine production GO:0001816 247 0.083
guanosine containing compound metabolic process GO:1901068 244 0.082
morphogenesis of an epithelium GO:0002009 60 0.080
Zebrafish
regulation of actin polymerization or depolymerization GO:0008064 56 0.080
actin filament polymerization GO:0030041 45 0.080
long term memory GO:0007616 2 0.078
regulation of collateral sprouting GO:0048670 2 0.077
negative regulation of kinase activity GO:0033673 106 0.076
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.075
cation transport GO:0006812 331 0.074
compound eye development GO:0048749 1 0.073
actin polymerization or depolymerization GO:0008154 56 0.073
regulation of epithelial cell migration GO:0010632 93 0.073
Human
cellular macromolecular complex assembly GO:0034622 324 0.072
Yeast
actin filament based movement GO:0030048 17 0.072
negative regulation of apoptotic process GO:0043066 316 0.071
regulation of myelination GO:0031641 1 0.068
neuron projection development GO:0031175 106 0.068
regulation of wnt signaling pathway GO:0030111 123 0.068
response to organonitrogen compound GO:0010243 156 0.068
Human Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.068
Human
negative regulation of protein phosphorylation GO:0001933 140 0.067
Human
regulation of protein localization GO:0032880 296 0.066
Human Mouse
positive regulation of lamellipodium assembly GO:0010592 9 0.066
eye development GO:0001654 42 0.065
Zebrafish Mouse
establishment or maintenance of cell polarity GO:0007163 31 0.064
Zebrafish Mouse Worm
positive regulation of cell proliferation GO:0008284 301 0.063
positive regulation of interleukin 5 production GO:0032754 3 0.063
negative regulation of protein kinase activity GO:0006469 98 0.062
Human
determination of adult lifespan GO:0008340 2 0.062
mitotic cell cycle GO:0000278 326 0.062
Human Zebrafish
single organism membrane organization GO:0044802 268 0.061
Human Mouse
primary neural tube formation GO:0014020 3 0.061
memory GO:0007613 3 0.060
organophosphate biosynthetic process GO:0090407 163 0.059
positive regulation of lamellipodium organization GO:1902745 12 0.059
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.059
mitochondrion organization GO:0007005 156 0.059
Human
cell cell signaling GO:0007267 155 0.058
epithelial cell differentiation GO:0030855 141 0.057
central nervous system development GO:0007417 123 0.057
Zebrafish
establishment of spindle orientation GO:0051294 9 0.056
Zebrafish
regulation of cell cycle GO:0051726 393 0.056
Human
regulation of anatomical structure size GO:0090066 101 0.055
regulation of neurogenesis GO:0050767 82 0.055
protein autophosphorylation GO:0046777 123 0.054
purine nucleoside monophosphate metabolic process GO:0009126 186 0.054
response to cytokine GO:0034097 232 0.053
regulation of response to external stimulus GO:0032101 222 0.053
nucleoside catabolic process GO:0009164 408 0.052
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.052
membrane organization GO:0061024 292 0.052
Human Mouse
regulation of map kinase activity GO:0043405 108 0.051
Human
pattern specification process GO:0007389 43 0.051
ubiquitin dependent protein catabolic process GO:0006511 206 0.050
cell morphogenesis involved in differentiation GO:0000904 144 0.050
single organism carbohydrate metabolic process GO:0044723 193 0.050
Human
regulation of ion transport GO:0043269 189 0.050
Human
positive regulation of nervous system development GO:0051962 54 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
positive regulation of cell migration GO:0030335 172 0.048
Human
establishment of epithelial cell polarity GO:0090162 2 0.047
neuron differentiation GO:0030182 138 0.047
cardiovascular system development GO:0072358 262 0.047
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 22 0.047
endomembrane system organization GO:0010256 196 0.047
Human Mouse
oxidation reduction process GO:0055114 396 0.046
Human
positive regulation of protein complex assembly GO:0031334 86 0.046
head development GO:0060322 108 0.046
Zebrafish
neuronal action potential GO:0019228 9 0.046
cell part morphogenesis GO:0032990 137 0.046
developmental cell growth GO:0048588 18 0.046
establishment of apical basal cell polarity GO:0035089 1 0.046
Mouse
cellular protein complex assembly GO:0043623 188 0.045
biological adhesion GO:0022610 331 0.045
regulation of neuron differentiation GO:0045664 70 0.044
actin mediated cell contraction GO:0070252 12 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.044
cell junction organization GO:0034330 79 0.044
phospholipid catabolic process GO:0009395 12 0.044
Human
positive regulation of cytoskeleton organization GO:0051495 83 0.043
protein processing GO:0016485 226 0.043
Human
defense response GO:0006952 315 0.043
gastrulation GO:0007369 51 0.042
Zebrafish
cell projection morphogenesis GO:0048858 129 0.042
positive regulation of interleukin 13 production GO:0032736 4 0.042
epidermis development GO:0008544 59 0.042
embryo development GO:0009790 123 0.042
Zebrafish Worm
negative regulation of transferase activity GO:0051348 124 0.042
Human
positive regulation of actin filament bundle assembly GO:0032233 25 0.041
wnt signaling pathway GO:0016055 156 0.041
regulation of protein transport GO:0051223 213 0.041
purine ribonucleoside metabolic process GO:0046128 437 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
cellular response to nitrogen compound GO:1901699 144 0.040
Human Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.039
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.039
epithelial cell migration GO:0010631 119 0.038
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.038
Human
glycerolipid metabolic process GO:0046486 107 0.038
cell migration involved in gastrulation GO:0042074 1 0.038
Zebrafish
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.038
regulation of cell projection assembly GO:0060491 47 0.038
positive regulation of meiotic cell cycle GO:0051446 2 0.037
single organism reproductive process GO:0044702 98 0.037
Worm
cell cell junction organization GO:0045216 69 0.036
purine containing compound catabolic process GO:0072523 411 0.036
single organism cellular localization GO:1902580 332 0.036
Human Zebrafish Mouse
sensory perception GO:0007600 103 0.036
single organismal cell cell adhesion GO:0016337 148 0.036
cell junction assembly GO:0034329 67 0.036
protein oligomerization GO:0051259 173 0.036
regulation of actin filament length GO:0030832 56 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
developmental growth GO:0048589 48 0.035
negative regulation of cell differentiation GO:0045596 171 0.035
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.035
Zebrafish Mouse
maintenance of cell polarity GO:0030011 2 0.035
Zebrafish
sex differentiation GO:0007548 45 0.034
Worm
response to other organism GO:0051707 261 0.034
regulation of dephosphorylation GO:0035303 96 0.034
Human
golgi organization GO:0007030 38 0.034
positive regulation of endothelial cell migration GO:0010595 39 0.034
Human
skin development GO:0043588 76 0.034
regulation of cell motility GO:2000145 299 0.034
Human
protein maturation GO:0051604 233 0.034
Human
cellular response to cytokine stimulus GO:0071345 181 0.033
response to oxygen containing compound GO:1901700 369 0.033
Human Mouse
circulatory system development GO:0072359 262 0.033
Zebrafish
lipid modification GO:0030258 84 0.033
Human
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.032
positive regulation of protein polymerization GO:0032273 45 0.032
response to abiotic stimulus GO:0009628 336 0.032
Human
neuromuscular junction development GO:0007528 3 0.032
developmental growth involved in morphogenesis GO:0060560 23 0.032
calcium ion transport GO:0006816 147 0.032
apoptotic signaling pathway GO:0097190 268 0.031
regulation of growth GO:0040008 165 0.031
Human
negative regulation of cell death GO:0060548 345 0.031
negative regulation of protein processing GO:0010955 142 0.031
Human
divalent inorganic cation transport GO:0072511 158 0.031
nucleotide catabolic process GO:0009166 408 0.031
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.031
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
transmission of nerve impulse GO:0019226 11 0.030
golgi vesicle transport GO:0048193 80 0.030
response to metal ion GO:0010038 84 0.029
establishment of mitotic spindle localization GO:0040001 8 0.029
Zebrafish
response to hormone GO:0009725 175 0.029
Human Mouse
maintenance of location GO:0051235 112 0.029
epithelial cell proliferation GO:0050673 128 0.029
Human
single organism cell adhesion GO:0098602 179 0.029
axon development GO:0061564 34 0.029
locomotory behavior GO:0007626 1 0.029
regulation of neuroblast proliferation GO:1902692 3 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.028
Human
positive regulation of transport GO:0051050 336 0.028
Human Mouse
nucleoside monophosphate metabolic process GO:0009123 191 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
embryonic organ morphogenesis GO:0048562 24 0.028
spermatid differentiation GO:0048515 4 0.028
immune response GO:0006955 307 0.028
actin filament bundle organization GO:0061572 54 0.028
regulation of mitotic cell cycle GO:0007346 189 0.027
secretion GO:0046903 254 0.027
embryonic eye morphogenesis GO:0048048 2 0.027
regulation of extent of cell growth GO:0061387 9 0.027
regulation of axonogenesis GO:0050770 16 0.027
immune system development GO:0002520 195 0.027
reproductive system development GO:0061458 56 0.027
Worm
proteasomal protein catabolic process GO:0010498 176 0.027
intracellular protein transport GO:0006886 270 0.027
Human
phagocytosis GO:0006909 42 0.027
establishment of nucleus localization GO:0040023 1 0.026
Zebrafish
regulation of non canonical wnt signaling pathway GO:2000050 4 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
regulation of cytokine production GO:0001817 232 0.026
rhythmic behavior GO:0007622 2 0.026
regulation of cell adhesion GO:0030155 166 0.026
blood vessel development GO:0001568 172 0.026
negative regulation of protein maturation GO:1903318 142 0.026
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.026
Human
purine ribonucleotide biosynthetic process GO:0009152 79 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
Human
cell growth GO:0016049 160 0.026
Human
protein catabolic process GO:0030163 325 0.026
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
Human
regulation of intracellular transport GO:0032386 195 0.025
lamellipodium assembly GO:0030032 26 0.025
regulation of ion transmembrane transport GO:0034765 132 0.025
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
metal ion transport GO:0030001 272 0.024
peptidyl tyrosine modification GO:0018212 170 0.024
Human
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
protein k33 linked ubiquitination GO:1990390 1 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
protein localization to membrane GO:0072657 160 0.024
Human Mouse
response to nitrogen compound GO:1901698 184 0.024
Human Mouse
stem cell proliferation GO:0072089 25 0.024
Zebrafish
negative regulation of filopodium assembly GO:0051490 0 0.024
filopodium assembly GO:0046847 18 0.024
photoreceptor cell differentiation GO:0046530 2 0.024
Mouse
epithelial cell development GO:0002064 34 0.024
organelle assembly GO:0070925 176 0.024
Yeast
positive regulation of cytokine production GO:0001819 167 0.024
positive regulation of transferase activity GO:0051347 227 0.023
Human
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.023
cellular response to external stimulus GO:0071496 111 0.023
regulation of proteasomal protein catabolic process GO:0061136 87 0.023
divalent metal ion transport GO:0070838 152 0.023
spermatid development GO:0007286 4 0.023
establishment of spindle localization GO:0051293 12 0.023
Zebrafish
ribose phosphate biosynthetic process GO:0046390 82 0.023
inorganic cation transmembrane transport GO:0098662 194 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.023
Worm
embryonic axis specification GO:0000578 5 0.023
carbohydrate transport GO:0008643 37 0.023
Human Mouse
cellular protein catabolic process GO:0044257 261 0.023
vasculature development GO:0001944 181 0.022
response to wounding GO:0009611 168 0.022
regulation of body fluid levels GO:0050878 99 0.022
chemical homeostasis GO:0048878 306 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
Human
actin filament bundle assembly GO:0051017 54 0.022
covalent chromatin modification GO:0016569 254 0.022
cellular carbohydrate metabolic process GO:0044262 84 0.022
Human
guanosine containing compound catabolic process GO:1901069 239 0.021
cellular homeostasis GO:0019725 196 0.021
regulation of stress activated mapk cascade GO:0032872 84 0.021
regulation of gtpase activity GO:0043087 180 0.021
protein targeting GO:0006605 187 0.021
Human
protein kinase b signaling GO:0043491 69 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
Human
mitotic cytokinesis GO:0000281 19 0.021
activation of protein kinase activity GO:0032147 90 0.021
neuron development GO:0048666 113 0.021
motor neuron axon guidance GO:0008045 2 0.021
cilium assembly GO:0042384 63 0.021
lymphocyte activation GO:0046649 133 0.021
positive regulation of actin filament polymerization GO:0030838 38 0.021
rho protein signal transduction GO:0007266 26 0.020
nucleus localization GO:0051647 1 0.020
Zebrafish
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
cation transmembrane transport GO:0098655 238 0.020
hexose transport GO:0008645 30 0.020
Human Mouse
sensory organ morphogenesis GO:0090596 21 0.020
Zebrafish Mouse
regulation of lamellipodium organization GO:1902743 19 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
negative regulation of protein complex assembly GO:0031333 43 0.020
Human
ras protein signal transduction GO:0007265 73 0.020
purine nucleoside biosynthetic process GO:0042451 23 0.020
phospholipid metabolic process GO:0006644 99 0.020
Human
positive regulation of immune system process GO:0002684 283 0.020
neuron projection morphogenesis GO:0048812 50 0.020
protein localization to nucleus GO:0034504 136 0.020
Human
mating GO:0007618 1 0.020
convergent extension GO:0060026 1 0.019
regulation of calcium ion transport GO:0051924 79 0.019
peptidyl threonine phosphorylation GO:0018107 41 0.019
Human
response to growth factor GO:0070848 205 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
positive regulation of map kinase activity GO:0043406 80 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
negative regulation of rho gtpase activity GO:0034259 4 0.019
response to lipid GO:0033993 206 0.019
tube closure GO:0060606 3 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
blood coagulation GO:0007596 76 0.018
maintenance of location in cell GO:0051651 62 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.018
macroautophagy GO:0016236 39 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
positive regulation of synaptic transmission GO:0050806 4 0.018
nucleotide biosynthetic process GO:0009165 109 0.018
schwann cell differentiation GO:0014037 1 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
developmental process involved in reproduction GO:0003006 66 0.018
Worm
monocarboxylic acid catabolic process GO:0072329 37 0.018
Human
cellular response to dna damage stimulus GO:0006974 379 0.018
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
positive regulation of anoikis GO:2000210 4 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
regulation of cell development GO:0060284 161 0.018
negative regulation of cytoskeleton organization GO:0051494 45 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.017
axonogenesis GO:0007409 31 0.017
interleukin 13 secretion GO:0072611 2 0.017
ion transmembrane transport GO:0034220 338 0.017
Human
gtp catabolic process GO:0006184 237 0.017
camera type eye development GO:0043010 25 0.017
Zebrafish
regulation of phosphatase activity GO:0010921 81 0.017
regulation of protein targeting GO:1903533 91 0.017
response to bacterium GO:0009617 144 0.017
negative regulation of cell migration GO:0030336 102 0.017
morphogenesis of an epithelial sheet GO:0002011 12 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
post golgi vesicle mediated transport GO:0006892 36 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
meiotic chromosome segregation GO:0045132 4 0.017
sequestering of metal ion GO:0051238 24 0.017
transmembrane transport GO:0055085 399 0.017
Human
regulation of binding GO:0051098 111 0.017
regulation of cell cycle process GO:0010564 266 0.017
calcium ion transmembrane transport GO:0070588 76 0.017
regulation of nervous system development GO:0051960 88 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
dna repair GO:0006281 198 0.016
Human
tissue migration GO:0090130 119 0.016
Human Zebrafish
positive regulation of t cell cytokine production GO:0002726 4 0.016
response to estrogen GO:0043627 47 0.016
aging GO:0007568 66 0.016
Human
regulation of cytoplasmic transport GO:1903649 149 0.016
epithelium migration GO:0090132 119 0.016
Human
negative regulation of catabolic process GO:0009895 104 0.016
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
fatty acid catabolic process GO:0009062 29 0.016
Human
positive regulation of stress fiber assembly GO:0051496 22 0.016
regulation of cellular response to stress GO:0080135 244 0.016
Human
regulation of protein secretion GO:0050708 86 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
response to extracellular stimulus GO:0009991 85 0.016
cell competition in a multicellular organism GO:0035212 1 0.016
chromatin organization GO:0006325 351 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
Human Mouse
stress activated mapk cascade GO:0051403 93 0.016
positive regulation of cell projection organization GO:0031346 64 0.016
ribonucleoside biosynthetic process GO:0042455 25 0.015
innate immune response GO:0045087 178 0.015
centrosome localization GO:0051642 3 0.015
peroxisome degradation GO:0030242 1 0.015
Yeast
jnk cascade GO:0007254 80 0.015
t cell activation GO:0042110 99 0.015
protein dephosphorylation GO:0006470 81 0.015
Human
negative regulation of programmed cell death GO:0043069 321 0.015
negative regulation of dephosphorylation GO:0035305 63 0.015
positive regulation of glucosylceramide catabolic process GO:2000753 1 0.015
Human
embryonic pattern specification GO:0009880 5 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
sequestering of calcium ion GO:0051208 17 0.015

PRKCI disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.052
muscular disease DOID:0080000 114 0.052
heart disease DOID:114 68 0.052
cardiomyopathy DOID:0050700 50 0.052
intrinsic cardiomyopathy DOID:0060036 50 0.052
cardiovascular system disease DOID:1287 106 0.052
musculoskeletal system disease DOID:17 223 0.052
muscle tissue disease DOID:66 113 0.052
connective tissue disease DOID:65 109 0.018
central nervous system disease DOID:331 186 0.017
Human
neurodegenerative disease DOID:1289 102 0.017
Human
nervous system disease DOID:863 431 0.017
Human
sensory system disease DOID:0050155 203 0.015