Homo sapiens

130 known processes

PRKCZ

protein kinase C, zeta

(Aliases: PKC2,PKC-ZETA)

PRKCZ biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuronal stem cell division GO:0036445 1 1.000
asymmetric neuroblast division GO:0055059 1 1.000
somatic stem cell division GO:0048103 1 1.000
asymmetric stem cell division GO:0098722 1 1.000
neuroblast division GO:0055057 1 1.000
phospholipid transport GO:0015914 23 1.000
Human
phospholipid catabolic process GO:0009395 12 1.000
Human
neuroblast proliferation GO:0007405 4 1.000
stem cell division GO:0017145 2 1.000
establishment of neuroblast polarity GO:0045200 1 0.999
negative regulation of protein phosphorylation GO:0001933 140 0.998
negative regulation of lipid catabolic process GO:0050995 9 0.998
Human
positive regulation of lamellipodium assembly GO:0010592 9 0.997
collateral sprouting GO:0048668 2 0.994
negative regulation of t cell apoptotic process GO:0070233 4 0.992
Human
establishment or maintenance of neuroblast polarity GO:0045196 1 0.991
regulation of kinase activity GO:0043549 314 0.987
Human Rat
single organism cellular localization GO:1902580 332 0.985
Human Mouse Rat
negative regulation of protein metabolic process GO:0051248 391 0.981
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.978
negative regulation of phosphorus metabolic process GO:0010563 267 0.974
negative regulation of phosphorylation GO:0042326 174 0.973
tissue morphogenesis GO:0048729 96 0.973
Zebrafish
oogenesis GO:0048477 2 0.971
morphogenesis of a polarized epithelium GO:0001738 3 0.970
peroxisome degradation GO:0030242 1 0.967
Yeast
negative regulation of cellular protein metabolic process GO:0032269 353 0.965
positive regulation of fatty acid beta oxidation GO:0032000 5 0.957
Human
neural tube formation GO:0001841 3 0.948
tube development GO:0035295 125 0.938
negative regulation of protein modification process GO:0031400 200 0.937
tube morphogenesis GO:0035239 95 0.933
digestive tract development GO:0048565 75 0.932
positive regulation of lamellipodium organization GO:1902745 12 0.931
regulation of protein kinase activity GO:0045859 289 0.931
Human Rat
cloaca development GO:0035844 1 0.930
female gamete generation GO:0007292 2 0.925
embryonic epithelial tube formation GO:0001838 4 0.917
protein targeting GO:0006605 187 0.908
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.905
specification of axis polarity GO:0065001 1 0.904
membrane organization GO:0061024 292 0.896
Human Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.891
anterior posterior axis specification GO:0009948 2 0.888
positive regulation of protein phosphorylation GO:0001934 313 0.878
Human Rat
morphogenesis of embryonic epithelium GO:0016331 4 0.876
negative regulation of protein kinase activity GO:0006469 98 0.872
Human
biological adhesion GO:0022610 331 0.871
Rat
single organism membrane organization GO:0044802 268 0.870
Human Mouse
negative regulation of transferase activity GO:0051348 124 0.867
Human
polysaccharide biosynthetic process GO:0000271 27 0.866
Human
regulation of glycogen metabolic process GO:0070873 15 0.854
Human
carbohydrate metabolic process GO:0005975 207 0.852
Human
cell cell junction organization GO:0045216 69 0.846
Human
digestive tract morphogenesis GO:0048546 56 0.840
peptidyl threonine modification GO:0018210 45 0.826
Human
positive regulation of sphingomyelin catabolic process GO:2000755 1 0.821
Human
organophosphate ester transport GO:0015748 32 0.819
Human
regulation of cell growth GO:0001558 135 0.816
Human
intracellular protein transport GO:0006886 270 0.810
Human
segmentation GO:0035282 4 0.805
enzyme linked receptor protein signaling pathway GO:0007167 303 0.802
regulation of collateral sprouting GO:0048670 2 0.798
developmental cell growth GO:0048588 18 0.788
Mouse
organelle localization GO:0051640 84 0.784
Zebrafish Rat
regulation of sphingomyelin catabolic process GO:2000754 1 0.781
Human
vesicle mediated transport GO:0016192 371 0.781
Worm
positive regulation of cellular component movement GO:0051272 181 0.779
Human
mrna 3 end processing GO:0031124 24 0.776
Yeast
positive regulation of mapk cascade GO:0043410 190 0.773
cellular amino acid metabolic process GO:0006520 116 0.771
negative regulation of catalytic activity GO:0043086 335 0.764
Human Rat
regulation of growth GO:0040008 165 0.763
Human
regulation of transferase activity GO:0051338 355 0.754
Human Rat
amine metabolic process GO:0009308 44 0.753
Human
nuclear transport GO:0051169 179 0.748
Human
termination of signal transduction GO:0023021 3 0.740
Human
digestive system development GO:0055123 75 0.730
negative regulation of kinase activity GO:0033673 106 0.728
Human
regulation of rab protein signal transduction GO:0032483 39 0.727
regulation of cellular amine metabolic process GO:0033238 11 0.710
Human
positive regulation of glial cell proliferation GO:0060252 2 0.705
Human
rab protein signal transduction GO:0032482 4 0.701
protein targeting to nucleus GO:0044744 104 0.701
Human
regulation of polysaccharide biosynthetic process GO:0032885 20 0.698
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.687
granulocyte activation GO:0036230 10 0.686
Human
regulation of nucleoside metabolic process GO:0009118 209 0.684
cell junction organization GO:0034330 79 0.681
Human
glucosylceramide metabolic process GO:0006678 3 0.667
Human
regulation of filopodium assembly GO:0051489 13 0.662
endocytosis GO:0006897 159 0.662
Worm
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.661
Yeast
epithelium development GO:0060429 227 0.660
cardiovascular system development GO:0072358 262 0.653
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 50 0.651
Human
positive regulation of lipid catabolic process GO:0050996 13 0.650
Human
spinal cord development GO:0021510 4 0.643
cell fate commitment GO:0045165 27 0.643
epithelial cell proliferation GO:0050673 128 0.632
Human
cellular polysaccharide biosynthetic process GO:0033692 21 0.627
Human
regulation of glycogen biosynthetic process GO:0005979 14 0.626
Human
regulation of map kinase activity GO:0043405 108 0.623
Human
nervous system development GO:0007399 293 0.611
Human Zebrafish Mouse
carboxylic acid transport GO:0046942 63 0.610
Human
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.607
Human
regulation of establishment of protein localization GO:0070201 242 0.606
Human Mouse Rat
post embryonic development GO:0009791 2 0.605
Worm
anterior posterior axis specification embryo GO:0008595 2 0.602
embryonic morphogenesis GO:0048598 85 0.600
cell projection organization GO:0030030 252 0.578
Human Mouse
positive regulation of cellular component organization GO:0051130 376 0.576
Human
regulation of protein localization to plasma membrane GO:1903076 40 0.568
Human
myeloid leukocyte activation GO:0002274 34 0.568
Human
establishment of organelle localization GO:0051656 59 0.555
Zebrafish Rat
monocarboxylic acid catabolic process GO:0072329 37 0.555
Human
gastrulation GO:0007369 51 0.554
negative regulation of intracellular signal transduction GO:1902532 183 0.552
Human
positive regulation of glucosylceramide catabolic process GO:2000753 1 0.548
Human
morphogenesis of an epithelium GO:0002009 60 0.541
regulation of cellular amino acid metabolic process GO:0006521 6 0.536
cell projection morphogenesis GO:0048858 129 0.534
Mouse
cell adhesion GO:0007155 325 0.528
Rat
cellular biogenic amine metabolic process GO:0006576 34 0.520
Human
establishment of cell polarity GO:0030010 22 0.508
Rat
neuron projection development GO:0031175 106 0.506
Human Mouse
anion transport GO:0006820 161 0.502
Human
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.500
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.498
Human Rat
positive regulation of kinase activity GO:0033674 204 0.498
Human Rat
cellular response to hormone stimulus GO:0032870 125 0.497
endomembrane system organization GO:0010256 196 0.496
Human Mouse
single organism nuclear import GO:1902593 104 0.496
Human
adherens junction organization GO:0034332 36 0.495
regulation of locomotion GO:0040012 329 0.490
Human Zebrafish
regulation of fatty acid transport GO:2000191 8 0.484
Human
carboxylic acid catabolic process GO:0046395 71 0.482
Human
regulation of proteolysis GO:0030162 293 0.482
Human
neural tube development GO:0021915 9 0.482
mitotic cell cycle process GO:1903047 286 0.479
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.473
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.471
Zebrafish
positive regulation of locomotion GO:0040017 186 0.464
Human
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.464
Human
regulation of cellular component movement GO:0051270 334 0.463
Human Zebrafish
positive regulation of protein localization to plasma membrane GO:1903078 20 0.461
Human
epidermis morphogenesis GO:0048730 3 0.457
regulation of rab gtpase activity GO:0032313 39 0.456
neuron differentiation GO:0030182 138 0.453
Human Mouse
negative regulation of protein catabolic process GO:0042177 59 0.446
Human
positive regulation of rab gtpase activity GO:0032851 39 0.441
neuromuscular junction development GO:0007528 3 0.440
cellular component morphogenesis GO:0032989 314 0.436
Mouse
regulation of lamellipodium assembly GO:0010591 14 0.436
oocyte differentiation GO:0009994 2 0.428
cytoplasmic mrna processing body assembly GO:0033962 10 0.421
Yeast
cellular response to nitrogen compound GO:1901699 144 0.418
synapse organization GO:0050808 14 0.413
rna processing GO:0006396 255 0.410
Yeast
positive regulation of gliogenesis GO:0014015 4 0.409
Human
oocyte development GO:0048599 1 0.407
regulation of glucan biosynthetic process GO:0010962 14 0.406
Human
cell division GO:0051301 168 0.401
Worm
regulation of cell migration GO:0030334 289 0.400
Human Zebrafish
lipid metabolic process GO:0006629 381 0.398
Human
protein import GO:0017038 130 0.397
Human
protein targeting to membrane GO:0006612 42 0.396
neurogenesis GO:0022008 169 0.396
Human Zebrafish Mouse
hexose metabolic process GO:0019318 55 0.394
Human
cellular response to cytokine stimulus GO:0071345 181 0.394
positive regulation of glycogen biosynthetic process GO:0045725 10 0.389
Human
maintenance of cell polarity GO:0030011 2 0.389
lamellipodium organization GO:0097581 30 0.387
superoxide metabolic process GO:0006801 20 0.386
Human
glucosylceramide catabolic process GO:0006680 2 0.383
Human
developmental growth GO:0048589 48 0.373
Mouse
stem cell proliferation GO:0072089 25 0.372
positive regulation of developmental process GO:0051094 314 0.371
Human Mouse
response to cytokine GO:0034097 232 0.370
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.364
regulation of cell development GO:0060284 161 0.362
Human
phospholipid metabolic process GO:0006644 99 0.362
Human
mitochondrion organization GO:0007005 156 0.362
Human
establishment of epithelial cell polarity GO:0090162 2 0.359
cytoplasmic transport GO:0016482 379 0.355
Human
regulation of cell differentiation GO:0045595 393 0.352
Human Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.352
Human
chemical homeostasis GO:0048878 306 0.351
glial cell migration GO:0008347 4 0.346
phagocytosis GO:0006909 42 0.345
positive regulation of superoxide anion generation GO:0032930 4 0.344
Human
regulation of protein localization GO:0032880 296 0.339
Human Mouse Rat
cellular lipid catabolic process GO:0044242 65 0.335
Human
peroxisome organization GO:0007031 28 0.335
Yeast
protein maturation GO:0051604 233 0.334
Human
regulation of ceramide biosynthetic process GO:2000303 2 0.334
Human
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.333
Human
regulation of gtpase activity GO:0043087 180 0.327
long chain fatty acid transport GO:0015909 18 0.319
Human
positive regulation of transport GO:0051050 336 0.312
Human Mouse Rat
alcohol metabolic process GO:0006066 114 0.312
Human
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.308
regulation of lamellipodium organization GO:1902743 19 0.307
lamellipodium assembly GO:0030032 26 0.303
negative regulation of developmental process GO:0051093 247 0.301
Worm
positive regulation of nucleotide catabolic process GO:0030813 185 0.299
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.298
Human
cellular amine metabolic process GO:0044106 41 0.297
Human
small molecule catabolic process GO:0044282 92 0.296
Human
synaptic vesicle endocytosis GO:0048488 2 0.294
anion transmembrane transport GO:0098656 76 0.287
Human
embryonic organ development GO:0048568 36 0.287
regulation of membrane potential GO:0042391 95 0.287
Rat
determination of adult lifespan GO:0008340 2 0.282
peripheral nervous system development GO:0007422 2 0.281
establishment or maintenance of cell polarity GO:0007163 31 0.276
Rat Worm
cell growth GO:0016049 160 0.271
Human Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.271
establishment of planar polarity GO:0001736 3 0.271
positive regulation of cell development GO:0010720 92 0.268
Human
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.267
regulation of generation of precursor metabolites and energy GO:0043467 27 0.265
Human
embryonic heart tube development GO:0035050 9 0.264
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.264
Human Rat
leukocyte apoptotic process GO:0071887 31 0.258
Human
regulation of neuroblast proliferation GO:1902692 3 0.257
microtubule based process GO:0007017 210 0.256
Mouse Rat
t cell apoptotic process GO:0070231 12 0.255
Human
regulation of cell morphogenesis GO:0022604 153 0.254
glucan biosynthetic process GO:0009250 16 0.252
Human
pattern specification process GO:0007389 43 0.249
lipid catabolic process GO:0016042 84 0.249
Human
cytokine production GO:0001816 247 0.248
Mouse
monosaccharide transport GO:0015749 32 0.248
Human Rat
peptidyl serine phosphorylation GO:0018105 101 0.246
microtubule cytoskeleton organization GO:0000226 176 0.245
Mouse
regulation of lipid biosynthetic process GO:0046890 47 0.240
Human
regulation of carbohydrate metabolic process GO:0006109 54 0.239
Human
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.238
Human
mitotic cell cycle GO:0000278 326 0.238
Human
protein localization to plasma membrane GO:0072659 93 0.238
Human Mouse
synapse assembly GO:0007416 8 0.238
protein processing GO:0016485 226 0.236
Human
regulation of epithelial cell proliferation GO:0050678 113 0.236
Human
heart development GO:0007507 95 0.231
multicellular organismal aging GO:0010259 3 0.229
negative regulation of glial cell apoptotic process GO:0034351 6 0.228
Human
establishment of protein localization to membrane GO:0090150 121 0.227
Human
negative regulation of cellular component organization GO:0051129 235 0.227
positive regulation of cell size GO:0045793 3 0.226
neural precursor cell proliferation GO:0061351 6 0.226
circulatory system development GO:0072359 262 0.226
Zebrafish
cell projection assembly GO:0030031 126 0.225
insulin receptor signaling pathway GO:0008286 23 0.218
cell junction maintenance GO:0034331 4 0.218
positive regulation of cell cycle GO:0045787 140 0.211
Human
filopodium assembly GO:0046847 18 0.211
regeneration GO:0031099 4 0.211
regulation of fatty acid beta oxidation GO:0031998 8 0.210
Human
regulation of phospholipid transport GO:2001138 4 0.206
Human
regulation of extent of cell growth GO:0061387 9 0.204
protein localization to organelle GO:0033365 280 0.203
Human
fatty acid catabolic process GO:0009062 29 0.203
Human
lymphocyte homeostasis GO:0002260 4 0.203
Human
epithelial cell differentiation GO:0030855 141 0.201
tripartite regional subdivision GO:0007351 2 0.195
response to abiotic stimulus GO:0009628 336 0.195
Human
epithelial cell migration GO:0010631 119 0.194
Human Zebrafish
regulation of peptidyl serine phosphorylation GO:0033135 50 0.194
Human
ribonucleoprotein complex biogenesis GO:0022613 116 0.194
Yeast
positive regulation of phospholipid scramblase activity GO:1900163 1 0.192
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.192
Human
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.192
Human
regulation of cellular component biogenesis GO:0044087 281 0.189
positive regulation of glucose metabolic process GO:0010907 12 0.187
Human
positive regulation of cell proliferation GO:0008284 301 0.187
Human Rat
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.185
Human
cellular ketone metabolic process GO:0042180 80 0.183
Human
ribonucleotide catabolic process GO:0009261 405 0.182
axonogenesis GO:0007409 31 0.182
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.180
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.180
cell morphogenesis GO:0000902 296 0.180
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.179
regulation of neuron differentiation GO:0045664 70 0.179
Human
negative regulation of fatty acid beta oxidation GO:0031999 1 0.178
Human
ion transmembrane transport GO:0034220 338 0.178
Human Rat
negative regulation of cell death GO:0060548 345 0.177
Human Rat
g1 s transition of mitotic cell cycle GO:0000082 78 0.177
Human
mrna catabolic process GO:0006402 56 0.177
Yeast
cellular response to endogenous stimulus GO:0071495 336 0.176
cell fate determination GO:0001709 3 0.176
epithelial tube morphogenesis GO:0060562 38 0.176
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.175
negative regulation of plasma membrane long chain fatty acid transport GO:0010748 4 0.175
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.174
ras protein signal transduction GO:0007265 73 0.173
polysaccharide metabolic process GO:0005976 33 0.172
Human
nucleocytoplasmic transport GO:0006913 176 0.171
Human
hindbrain development GO:0030902 3 0.170
cell proliferation in forebrain GO:0021846 1 0.169
renal system development GO:0072001 63 0.169
muscle cell fate commitment GO:0042693 4 0.166
regulation of cellular response to stress GO:0080135 244 0.165
Human
regulation of neuron projection development GO:0010975 57 0.165
Human
activation induced cell death of t cells GO:0006924 2 0.165
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.164
protein ubiquitination GO:0016567 314 0.164
Human
ceramide metabolic process GO:0006672 25 0.164
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.162
endothelial cell migration GO:0043542 86 0.160
Human Zebrafish
regulation of glial cell proliferation GO:0060251 4 0.160
Human
liposaccharide metabolic process GO:1903509 27 0.155
Human
endothelial cell apoptotic process GO:0072577 26 0.153
Human
nucleoside catabolic process GO:0009164 408 0.150
purine nucleoside catabolic process GO:0006152 398 0.149
purine containing compound catabolic process GO:0072523 411 0.147
negative regulation of ion transmembrane transport GO:0034766 26 0.146
Human
regulation of protein maturation GO:1903317 150 0.146
Human
positive regulation of lipid biosynthetic process GO:0046889 22 0.145
Human
negative regulation of apoptotic process GO:0043066 316 0.145
Human Rat
monosaccharide metabolic process GO:0005996 74 0.144
Human
protein localization to nucleus GO:0034504 136 0.144
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.141
Human Rat
lipid modification GO:0030258 84 0.141
Human
reactive nitrogen species metabolic process GO:2001057 3 0.139
axon development GO:0061564 34 0.139
regulation of fatty acid oxidation GO:0046320 9 0.137
Human
generation of neurons GO:0048699 152 0.136
Human Zebrafish Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.136
organic anion transport GO:0015711 103 0.134
Human
regulation of cell cycle GO:0051726 393 0.133
Human
regulation of response to external stimulus GO:0032101 222 0.133
regulation of ion transmembrane transport GO:0034765 132 0.132
Human
regulation of cell projection assembly GO:0060491 47 0.132
organ growth GO:0035265 12 0.130
positive regulation of endothelial cell proliferation GO:0001938 37 0.129
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.129
nucleoside triphosphate metabolic process GO:0009141 422 0.128
cell development GO:0048468 328 0.127
Human Mouse
establishment of vesicle localization GO:0051650 23 0.127
Rat
regulation of leukocyte apoptotic process GO:2000106 25 0.126
Human
regulation of cell shape GO:0008360 48 0.126
energy derivation by oxidation of organic compounds GO:0015980 43 0.126
Human
reproductive process GO:0022414 106 0.126
Worm
regulation of plasma lipoprotein particle levels GO:0097006 32 0.126
epithelium migration GO:0090132 119 0.125
Human Zebrafish
regulation of mismatch repair GO:0032423 2 0.125
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.125
skin development GO:0043588 76 0.125
lipid oxidation GO:0034440 33 0.124
Human
cellular carbohydrate metabolic process GO:0044262 84 0.124
Human
blastoderm segmentation GO:0007350 2 0.124
regionalization GO:0003002 29 0.123
developmental growth involved in morphogenesis GO:0060560 23 0.123
Mouse
regulation of translation GO:0006417 89 0.123
positive regulation of filopodium assembly GO:0051491 7 0.122
response to light stimulus GO:0009416 87 0.120
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.119
Human
regulation of phospholipid scramblase activity GO:1900161 1 0.118
Human
negative regulation of map kinase activity GO:0043407 27 0.117
Human
organic acid catabolic process GO:0016054 71 0.116
Human
mapk cascade GO:0000165 288 0.116
positive regulation of protein kinase activity GO:0045860 190 0.116
Human Rat
centrosome localization GO:0051642 3 0.116
rna catabolic process GO:0006401 71 0.113
Yeast
negative regulation of epithelial to mesenchymal transition GO:0010719 14 0.113
cellular response to oxygen containing compound GO:1901701 276 0.113
positive regulation of cell growth GO:0030307 48 0.113
Human
epithelial tube formation GO:0072175 5 0.112
developmental process involved in reproduction GO:0003006 66 0.111
Worm
establishment of protein localization to organelle GO:0072594 172 0.111
Human
brain development GO:0007420 97 0.110
tissue migration GO:0090130 119 0.109
Human Zebrafish
reproduction GO:0000003 63 0.109
Worm
reactive oxygen species metabolic process GO:0072593 75 0.108
Human
dephosphorylation GO:0016311 209 0.108
Human
regulation of dna repair GO:0006282 47 0.107
Human
reactive oxygen species biosynthetic process GO:1903409 4 0.107
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.106
regulation of glucose import GO:0046324 21 0.106
Human Rat
positive regulation of glycogen metabolic process GO:0070875 10 0.103
Human
neuron development GO:0048666 113 0.103
Human Mouse
establishment of apical basal cell polarity GO:0035089 1 0.102
activation of immune response GO:0002253 114 0.102
response to transforming growth factor beta GO:0071559 94 0.101
nitric oxide metabolic process GO:0046209 22 0.099
Human
regulation of meiotic cell cycle GO:0051445 4 0.098
regulation of purine nucleotide metabolic process GO:1900542 264 0.098
regulation of nervous system development GO:0051960 88 0.097
Human
regulation of cellular response to insulin stimulus GO:1900076 17 0.097
regulation of endothelial cell apoptotic process GO:2000351 24 0.096
Human
positive regulation of catabolic process GO:0009896 310 0.095
Human
cellular response to peptide GO:1901653 59 0.092
positive regulation of fatty acid metabolic process GO:0045923 11 0.091
Human
regulation of binding GO:0051098 111 0.091
positive regulation of cell migration GO:0030335 172 0.090
Human
negative regulation of programmed cell death GO:0043069 321 0.090
Human Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.090
regulation of endopeptidase activity GO:0052548 170 0.089
Human
cellular response to growth factor stimulus GO:0071363 197 0.089
membrane lipid catabolic process GO:0046466 10 0.088
Human
gtp catabolic process GO:0006184 237 0.088
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.088
positive regulation of fat cell differentiation GO:0045600 12 0.087
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.086
Human
notch signaling pathway GO:0007219 31 0.086
t cell homeostasis GO:0043029 3 0.086
Human
autophagy GO:0006914 88 0.085
Human Yeast
ameboidal type cell migration GO:0001667 135 0.084
Human Zebrafish
positive regulation of cytokine production GO:0001819 167 0.084
Mouse
sensory organ development GO:0007423 52 0.084
Zebrafish
cellular response to insulin stimulus GO:0032869 41 0.084
negative regulation of protein processing GO:0010955 142 0.083
Human
establishment of protein localization to plasma membrane GO:0090002 68 0.082
Human
negative regulation of peptidase activity GO:0010466 91 0.081
Human
response to organonitrogen compound GO:0010243 156 0.081
positive regulation of apoptotic process GO:0043065 246 0.080
Human
regulation of glucosylceramide catabolic process GO:2000752 1 0.080
Human
regulation of establishment of planar polarity GO:0090175 5 0.079
cellular senescence GO:0090398 34 0.079
Human
fatty acid metabolic process GO:0006631 115 0.078
Human
negative regulation of hydrolase activity GO:0051346 182 0.077
Human Rat
reproductive system development GO:0061458 56 0.077
Worm
positive regulation of cell projection organization GO:0031346 64 0.076
Human
organic acid transport GO:0015849 65 0.075
Human
response to radiation GO:0009314 151 0.075
Human
pronephros development GO:0048793 2 0.075
regulation of cytokine production GO:0001817 232 0.074
Mouse
carbohydrate biosynthetic process GO:0016051 42 0.074
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.074
regulation of developmental growth GO:0048638 30 0.073
protein localization to membrane GO:0072657 160 0.073
Human Mouse
growth GO:0040007 202 0.073
Human Mouse
establishment of mitotic spindle localization GO:0040001 8 0.073
cellular glucan metabolic process GO:0006073 22 0.072
Human
regulation of immune response GO:0050776 201 0.072
Mouse
nuclear import GO:0051170 106 0.072
Human
generation of precursor metabolites and energy GO:0006091 68 0.071
Human
protein dephosphorylation GO:0006470 81 0.071
Human
positive regulation of dna repair GO:0045739 25 0.071
Human
ribonucleoside catabolic process GO:0042454 406 0.071
cellular lipid metabolic process GO:0044255 303 0.071
Human
negative regulation of filopodium assembly GO:0051490 0 0.071
glycogen metabolic process GO:0005977 22 0.070
Human
cholesterol transport GO:0030301 39 0.070
forebrain generation of neurons GO:0021872 3 0.069
negative regulation of synaptic transmission GO:0050805 2 0.069
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.069
cellular macromolecule catabolic process GO:0044265 380 0.069
Yeast
lung epithelial cell differentiation GO:0060487 1 0.068
positive regulation of response to external stimulus GO:0032103 88 0.068
regulation of t cell apoptotic process GO:0070232 8 0.068
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.067
negative regulation of multicellular organismal process GO:0051241 317 0.067
Worm
fat cell differentiation GO:0045444 32 0.066
Human
positive regulation of hydrolase activity GO:0051345 331 0.066
Rat
regulation of anion transport GO:0044070 25 0.065
Human
activation of innate immune response GO:0002218 55 0.065
regulation of wound healing GO:0061041 56 0.064
positive regulation of ceramide biosynthetic process GO:2000304 1 0.064
Human
regulation of vesicle mediated transport GO:0060627 130 0.064
response to oxygen containing compound GO:1901700 369 0.064
regulation of axonogenesis GO:0050770 16 0.064
regulation of autophagy GO:0010506 52 0.064
Human
negative regulation of transport GO:0051051 176 0.063
Human
regulation of protein processing GO:0070613 150 0.063
Human
signal transduction by phosphorylation GO:0023014 297 0.063
axon regeneration GO:0031103 1 0.063
response to axon injury GO:0048678 1 0.063
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.063
response to uv GO:0009411 73 0.062
Human
positive regulation of oxidoreductase activity GO:0051353 26 0.062
Human
regulation of mapk cascade GO:0043408 262 0.062
chordate embryonic development GO:0043009 34 0.061
cell cell junction maintenance GO:0045217 4 0.061
negative regulation of transmembrane transport GO:0034763 29 0.061
Human
regulation of protein binding GO:0043393 66 0.060
cellular response to organic cyclic compound GO:0071407 127 0.060
multicellular organismal signaling GO:0035637 34 0.060
regulation of mrna catabolic process GO:0061013 13 0.059
Yeast
mismatch repair GO:0006298 15 0.059
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.058
negative regulation of cytokine production GO:0001818 82 0.058
receptor mediated endocytosis GO:0006898 84 0.058
Worm
lymphocyte apoptotic process GO:0070227 20 0.058
Human
response to growth factor GO:0070848 205 0.057
regulation of nitric oxide biosynthetic process GO:0045428 17 0.057
Human
protein import into nucleus GO:0006606 104 0.057
Human
negative regulation of oxidative stress induced cell death GO:1903202 17 0.057
single organism reproductive process GO:0044702 98 0.056
Worm
organ morphogenesis GO:0009887 147 0.056
Zebrafish
regulation of lymphocyte apoptotic process GO:0070228 15 0.056
Human
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.056
regulation of lipid catabolic process GO:0050994 23 0.056
Human
regulation of cell projection organization GO:0031344 107 0.056
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.056
hair follicle morphogenesis GO:0031069 2 0.055

PRKCZ disease predictions

Disease DO term ID Size Probability Func Analog Org