Homo sapiens

38 known processes

PRPF40A

PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)

(Aliases: FNBP3,HIP-10,FBP11,FLJ20585,FLAF1,NY-REN-6,FBP-11,Prp40,HYPA,HIP10)

PRPF40A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 255 0.984
rna splicing via transesterification reactions GO:0000375 90 0.981
rna splicing GO:0008380 131 0.978
regulation of meiotic cell cycle GO:0051445 4 0.951
regulation of cell cycle GO:0051726 393 0.916
embryo development GO:0009790 123 0.750
Worm
organelle fission GO:0048285 149 0.725
protein targeting to nucleus GO:0044744 104 0.716
regulation of proteasomal protein catabolic process GO:0061136 87 0.683
mrna processing GO:0006397 133 0.634
cellular macromolecular complex assembly GO:0034622 324 0.632
post embryonic development GO:0009791 2 0.613
Worm
positive regulation of transport GO:0051050 336 0.579
sex differentiation GO:0007548 45 0.567
endocytosis GO:0006897 159 0.566
Worm
protein modification by small protein conjugation GO:0032446 342 0.558
regulation of meiosis GO:0040020 3 0.470
positive regulation of cellular component organization GO:0051130 376 0.468
regulation of cellular component biogenesis GO:0044087 281 0.428
negative regulation of protein maturation GO:1903318 142 0.420
mrna metabolic process GO:0016071 175 0.388
positive regulation of cellular component biogenesis GO:0044089 158 0.370
receptor mediated endocytosis GO:0006898 84 0.351
Worm
nucleocytoplasmic transport GO:0006913 176 0.339
reproductive structure development GO:0048608 55 0.335
positive regulation of protein transport GO:0051222 135 0.334
cellular response to dna damage stimulus GO:0006974 379 0.328
positive regulation of cell death GO:0010942 263 0.323
regulation of cellular protein catabolic process GO:1903362 96 0.312
cellular amino acid metabolic process GO:0006520 116 0.286
regulation of nuclear division GO:0051783 65 0.277
regulation of protein transport GO:0051223 213 0.274
regulation of proteolysis GO:0030162 293 0.270
reproductive process GO:0022414 106 0.268
Worm
covalent chromatin modification GO:0016569 254 0.256
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.255
hematopoietic or lymphoid organ development GO:0048534 186 0.245
protein localization to organelle GO:0033365 280 0.244
nuclear division GO:0000280 128 0.229
immune system development GO:0002520 195 0.227
meiotic cell cycle GO:0051321 13 0.226
response to growth factor GO:0070848 205 0.225
regulation of protein complex assembly GO:0043254 147 0.221
regulation of intracellular transport GO:0032386 195 0.221
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.221
protein processing GO:0016485 226 0.219
actin cytoskeleton organization GO:0030036 207 0.201
actin filament based process GO:0030029 224 0.200
regulation of cellular response to stress GO:0080135 244 0.185
cell division GO:0051301 168 0.181
response to organic cyclic compound GO:0014070 204 0.173
protein maturation GO:0051604 233 0.166
nervous system development GO:0007399 293 0.158
chromatin modification GO:0016568 298 0.155
small gtpase mediated signal transduction GO:0007264 78 0.147
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.147
cellular ketone metabolic process GO:0042180 80 0.141
protein catabolic process GO:0030163 325 0.131
meiotic nuclear division GO:0007126 10 0.130
regulation of anatomical structure morphogenesis GO:0022603 286 0.129
ossification GO:0001503 121 0.126
regulation of mitotic cell cycle phase transition GO:1901990 118 0.126
positive regulation of immune system process GO:0002684 283 0.125
positive regulation of intracellular protein transport GO:0090316 76 0.124
hemopoiesis GO:0030097 180 0.123
cellular protein catabolic process GO:0044257 261 0.118
regulation of protein localization GO:0032880 296 0.108
positive regulation of proteolysis GO:0045862 142 0.106
negative regulation of cellular component organization GO:0051129 235 0.105
single organism nuclear import GO:1902593 104 0.104
negative regulation of catalytic activity GO:0043086 335 0.102
regulation of cell cycle phase transition GO:1901987 126 0.100
nuclear transport GO:0051169 179 0.099
negative regulation of protein processing GO:0010955 142 0.095
intracellular protein transport GO:0006886 270 0.095
cell cycle checkpoint GO:0000075 117 0.094
regulation of intracellular protein transport GO:0033157 123 0.092
blood vessel morphogenesis GO:0048514 162 0.091
negative regulation of cellular protein metabolic process GO:0032269 353 0.091
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.089
regulation of cellular ketone metabolic process GO:0010565 50 0.085
defense response GO:0006952 315 0.084
regulation of cell cycle process GO:0010564 266 0.084
cellular protein complex assembly GO:0043623 188 0.081
cellular amine metabolic process GO:0044106 41 0.076
response to biotic stimulus GO:0009607 276 0.075
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.075
protein localization to nucleus GO:0034504 136 0.075
ras protein signal transduction GO:0007265 73 0.073
regulation of peptidase activity GO:0052547 180 0.073
cellular macromolecule catabolic process GO:0044265 380 0.073
meiotic chromosome segregation GO:0045132 4 0.073
proteasomal protein catabolic process GO:0010498 176 0.072
cytoplasmic transport GO:0016482 379 0.072
regulation of response to dna damage stimulus GO:2001020 94 0.071
regulation of protein catabolic process GO:0042176 155 0.071
rna interference GO:0016246 4 0.070
regulation of nucleocytoplasmic transport GO:0046822 98 0.070
nuclear import GO:0051170 106 0.069
response to cytokine GO:0034097 232 0.066
mitotic spindle organization GO:0007052 27 0.065
reproductive system development GO:0061458 56 0.064
modification dependent macromolecule catabolic process GO:0043632 212 0.064
positive regulation of apoptotic process GO:0043065 246 0.064
development of primary sexual characteristics GO:0045137 35 0.063
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.062
negative regulation of mitotic cell cycle GO:0045930 102 0.061
regulation of chromatin organization GO:1902275 56 0.061
positive regulation of programmed cell death GO:0043068 249 0.060
ubiquitin dependent protein catabolic process GO:0006511 206 0.059
gonad development GO:0008406 34 0.059
negative regulation of catabolic process GO:0009895 104 0.058
positive regulation of intracellular transport GO:0032388 104 0.056
cell growth GO:0016049 160 0.056
cell cycle phase transition GO:0044770 173 0.054
regulation of establishment of protein localization GO:0070201 242 0.052
alternative mrna splicing via spliceosome GO:0000380 27 0.051
negative regulation of protein metabolic process GO:0051248 391 0.050
amine metabolic process GO:0009308 44 0.048
chromatin organization GO:0006325 351 0.047
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.046
negative regulation of phosphorus metabolic process GO:0010563 267 0.046
cytokinesis GO:0000910 96 0.045
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.045
mrna splicing via spliceosome GO:0000398 89 0.044
protein targeting GO:0006605 187 0.043
positive regulation of nfat protein import into nucleus GO:0051533 3 0.043
multi organism reproductive process GO:0044703 54 0.043
Worm
regulation of histone modification GO:0031056 47 0.041
cellular component morphogenesis GO:0032989 314 0.040
circulatory system development GO:0072359 262 0.039
regulation of cell division GO:0051302 116 0.039
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.037
regulation of nervous system development GO:0051960 88 0.037
reproduction GO:0000003 63 0.037
Worm
modification dependent protein catabolic process GO:0019941 209 0.035
blastoderm segmentation GO:0007350 2 0.035
positive regulation of cell differentiation GO:0045597 211 0.035
intrinsic apoptotic signaling pathway GO:0097193 127 0.035
segmentation GO:0035282 4 0.033
regulation of protein maturation GO:1903317 150 0.033
nucleosome organization GO:0034728 66 0.032
cellular response to organic cyclic compound GO:0071407 127 0.032
embryo development ending in birth or egg hatching GO:0009792 34 0.030
Worm
establishment of protein localization to organelle GO:0072594 172 0.030
microtubule cytoskeleton organization GO:0000226 176 0.030
developmental process involved in reproduction GO:0003006 66 0.030
chordate embryonic development GO:0043009 34 0.029
mitotic cell cycle process GO:1903047 286 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
negative regulation of cellular catabolic process GO:0031330 83 0.029
protein import GO:0017038 130 0.028
blood vessel development GO:0001568 172 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
regulation of small gtpase mediated signal transduction GO:0051056 156 0.027
regulation of vasculature development GO:1901342 97 0.026
response to external biotic stimulus GO:0043207 261 0.026
regulation of protein ubiquitination GO:0031396 95 0.026
cell development GO:0048468 328 0.026
regulation of mrna metabolic process GO:1903311 53 0.026
innate immune response GO:0045087 178 0.026
cellular response to growth factor stimulus GO:0071363 197 0.025
protein autophosphorylation GO:0046777 123 0.025
negative regulation of cell death GO:0060548 345 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
vasculature development GO:0001944 181 0.024
negative regulation of protein modification process GO:0031400 200 0.024
response to abiotic stimulus GO:0009628 336 0.024
protein ubiquitination GO:0016567 314 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.023
meiotic cell cycle process GO:1903046 8 0.023
nuclear export GO:0051168 69 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
histone modification GO:0016570 251 0.022
positive regulation of cell cycle process GO:0090068 106 0.021
erk1 and erk2 cascade GO:0070371 104 0.021
posttranscriptional gene silencing by rna GO:0035194 25 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
maintenance of location GO:0051235 112 0.021
negative regulation of cell cycle GO:0045786 193 0.021
cardiovascular system development GO:0072358 262 0.021
regulation of chromatin modification GO:1903308 51 0.020
stem cell differentiation GO:0048863 93 0.020
positive regulation of organelle organization GO:0010638 195 0.019
regulation of ras protein signal transduction GO:0046578 155 0.019
regulation of neuron differentiation GO:0045664 70 0.019
actin filament organization GO:0007015 128 0.019
negative regulation of proteolysis GO:0045861 132 0.018
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.018
positive regulation of transcription factor import into nucleus GO:0042993 25 0.018
positive regulation of growth GO:0045927 58 0.017
Worm
regulation of erk1 and erk2 cascade GO:0070372 99 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
spindle organization GO:0007051 53 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
regulation of dna metabolic process GO:0051052 153 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
regulation of chromosome organization GO:0033044 103 0.016
negative regulation of protein catabolic process GO:0042177 59 0.015
regulation of protein targeting GO:1903533 91 0.015
positive regulation of nervous system development GO:0051962 54 0.015
angiogenesis GO:0001525 147 0.015
negative regulation of protein complex assembly GO:0031333 43 0.015
protein deubiquitination GO:0016579 79 0.015
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
protein dna complex subunit organization GO:0071824 80 0.015
vesicle mediated transport GO:0016192 371 0.014
Worm
organelle assembly GO:0070925 176 0.014
leukocyte differentiation GO:0002521 98 0.014
growth GO:0040007 202 0.014
Worm
response to nitrogen compound GO:1901698 184 0.014
negative regulation of developmental process GO:0051093 247 0.014
spliceosomal complex assembly GO:0000245 17 0.013
response to lipid GO:0033993 206 0.013
positive regulation of response to dna damage stimulus GO:2001022 43 0.013
gamete generation GO:0007276 25 0.013
regulation of dna repair GO:0006282 47 0.013
establishment of rna localization GO:0051236 39 0.013
positive regulation of catabolic process GO:0009896 310 0.013
branch elongation of an epithelium GO:0060602 3 0.013
leukocyte activation GO:0045321 164 0.013
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of neurogenesis GO:0050767 82 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
Worm
cellular response to endogenous stimulus GO:0071495 336 0.012
molting cycle GO:0042303 28 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
regulation of rna splicing GO:0043484 62 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
ameboidal type cell migration GO:0001667 135 0.012
regulation of mrna processing GO:0050684 48 0.012
oogenesis GO:0048477 2 0.012
response to radiation GO:0009314 151 0.011
positive regulation of developmental process GO:0051094 314 0.011
Worm
negative regulation of cellular protein catabolic process GO:1903363 38 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
negative regulation of rho gtpase activity GO:0034259 4 0.011
regulation of protein processing GO:0070613 150 0.011
positive regulation of spindle checkpoint GO:0090232 7 0.011
positive regulation of cell cycle GO:0045787 140 0.011
embryonic organ development GO:0048568 36 0.011
regulation of cell activation GO:0050865 125 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
regulation of centriole replication GO:0046599 7 0.010
pattern specification process GO:0007389 43 0.010
negative regulation of growth GO:0045926 97 0.010
mature ribosome assembly GO:0042256 5 0.010
positive regulation of chromosome organization GO:2001252 41 0.010
neurogenesis GO:0022008 169 0.010
sexual reproduction GO:0019953 37 0.010
response to transforming growth factor beta GO:0071559 94 0.010

PRPF40A disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.011
nervous system disease DOID:863 431 0.011