Homo sapiens

24 known processes

PSMC5

proteasome (prosome, macropain) 26S subunit, ATPase, 5

(Aliases: S8,TBP10,p45/SUG,SUG-1,p45,SUG1,TRIP1)

PSMC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 209 0.999
proteasome regulatory particle assembly GO:0070682 2 0.997
Yeast
dna templated transcription initiation GO:0006352 35 0.997
Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.985
Yeast
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.982
Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.982
cellular protein catabolic process GO:0044257 261 0.981
blastocyst development GO:0001824 3 0.976
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.974
proteasome assembly GO:0043248 7 0.969
Yeast
ubiquitin dependent protein catabolic process GO:0006511 206 0.966
post embryonic development GO:0009791 2 0.959
Worm
proteasomal protein catabolic process GO:0010498 176 0.948
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.944
cellular macromolecule catabolic process GO:0044265 380 0.939
determination of adult lifespan GO:0008340 2 0.935
Worm
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.913
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.907
multicellular organismal aging GO:0010259 3 0.906
Worm
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.875
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.861
Yeast
protein catabolic process GO:0030163 325 0.841
purine nucleoside monophosphate catabolic process GO:0009128 158 0.828
Rat
cellular macromolecular complex assembly GO:0034622 324 0.817
Yeast
positive regulation of peptidase activity GO:0010952 88 0.793
cellular protein complex assembly GO:0043623 188 0.773
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.725
Rat
mitotic spindle elongation GO:0000022 4 0.685
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.663
Yeast
regulation of peptidase activity GO:0052547 180 0.621
ribonucleoside monophosphate metabolic process GO:0009161 187 0.606
Rat
cellular response to dna damage stimulus GO:0006974 379 0.590
Yeast Fly
nuclear division GO:0000280 128 0.569
Worm
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.553
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 186 0.537
Rat
mitotic cell cycle process GO:1903047 286 0.461
Worm
regulation of proteasomal protein catabolic process GO:0061136 87 0.456
oogenesis GO:0048477 2 0.456
positive regulation of endopeptidase activity GO:0010950 84 0.447
purine ribonucleoside metabolic process GO:0046128 437 0.446
Rat
ribonucleoside catabolic process GO:0042454 406 0.435
Rat
spindle elongation GO:0051231 4 0.433
ovarian follicle development GO:0001541 5 0.431
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.418
Rat
regulation of endopeptidase activity GO:0052548 170 0.375
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.360
atp metabolic process GO:0046034 176 0.344
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.336
Rat
positive regulation of hydrolase activity GO:0051345 331 0.323
regulation of cell cycle GO:0051726 393 0.318
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.287
Rat
protein k63 linked deubiquitination GO:0070536 21 0.284
regulation of mitotic cell cycle GO:0007346 189 0.283
Worm
negative regulation of peptidase activity GO:0010466 91 0.267
aging GO:0007568 66 0.258
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.208
Rat
regulation of apoptotic signaling pathway GO:2001233 175 0.202
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.198
Rat
nucleotide catabolic process GO:0009166 408 0.188
Rat
purine nucleoside catabolic process GO:0006152 398 0.176
Rat
rna splicing via transesterification reactions GO:0000375 90 0.175
mitotic cell cycle GO:0000278 326 0.174
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.170
Rat
purine nucleotide catabolic process GO:0006195 405 0.170
Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.168
Rat
rna interference GO:0016246 4 0.168
female gamete generation GO:0007292 2 0.149
ovulation cycle process GO:0022602 9 0.143
microtubule cytoskeleton organization GO:0000226 176 0.142
positive regulation of cellular catabolic process GO:0031331 284 0.138
regulation of protein import into nucleus GO:0042306 78 0.133
regulation of proteolysis GO:0030162 293 0.129
nucleoside phosphate catabolic process GO:1901292 412 0.128
Rat
regulation of cellular component biogenesis GO:0044087 281 0.126
Yeast Rat
reproduction GO:0000003 63 0.122
Worm
regulation of cell cycle process GO:0010564 266 0.116
Worm
neurogenesis GO:0022008 169 0.114
ribonucleoside triphosphate catabolic process GO:0009203 391 0.109
Rat
regulation of protein kinase activity GO:0045859 289 0.108
regulation of cellular protein catabolic process GO:1903362 96 0.108
positive regulation of catabolic process GO:0009896 310 0.108
positive regulation of cellular component organization GO:0051130 376 0.105
Yeast Rat
dna repair GO:0006281 198 0.105
Yeast
embryo development ending in birth or egg hatching GO:0009792 34 0.104
Worm
regulation of protein complex assembly GO:0043254 147 0.102
Yeast
osteoblast differentiation GO:0001649 92 0.102
vesicle mediated transport GO:0016192 371 0.102
protein deglycosylation GO:0006517 2 0.099
multicellular organism reproduction GO:0032504 42 0.093
organelle assembly GO:0070925 176 0.088
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.082
Yeast
positive regulation of protein complex assembly GO:0031334 86 0.082
Yeast
spermatid differentiation GO:0048515 4 0.081
cell cell signaling GO:0007267 155 0.078
growth GO:0040007 202 0.076
positive regulation of proteolysis GO:0045862 142 0.076
maintenance of protein location in cell GO:0032507 56 0.074
nervous system development GO:0007399 293 0.072
protein ubiquitination GO:0016567 314 0.071
protein secretion GO:0009306 98 0.069
mitochondrion organization GO:0007005 156 0.064
protein deubiquitination GO:0016579 79 0.062
embryo development GO:0009790 123 0.061
Worm
cell division GO:0051301 168 0.058
Worm
epithelium development GO:0060429 227 0.057
regulation of nucleotide catabolic process GO:0030811 205 0.056
microtubule based process GO:0007017 210 0.055
regulation of mrna metabolic process GO:1903311 53 0.054
ribonucleotide catabolic process GO:0009261 405 0.051
Rat
negative regulation of endopeptidase activity GO:0010951 84 0.051
positive regulation of cellular component biogenesis GO:0044089 158 0.051
Yeast Rat
posttranscriptional regulation of gene expression GO:0010608 213 0.050
regulation of kinase activity GO:0043549 314 0.048
posttranscriptional gene silencing by rna GO:0035194 25 0.048
spermatid development GO:0007286 4 0.048
regulation of mapk cascade GO:0043408 262 0.047
glycosyl compound catabolic process GO:1901658 413 0.046
Rat
synaptic transmission GO:0007268 61 0.044
endocytosis GO:0006897 159 0.044
positive regulation of nucleotide metabolic process GO:0045981 230 0.043
regulation of growth GO:0040008 165 0.042
nucleoside monophosphate catabolic process GO:0009125 159 0.042
Rat
oocyte development GO:0048599 1 0.041
neuronal action potential GO:0019228 9 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.041
Yeast
spindle organization GO:0007051 53 0.040
protein dna complex assembly GO:0065004 64 0.040
Yeast
receptor mediated endocytosis GO:0006898 84 0.040
regulation of protein ubiquitination GO:0031396 95 0.040
regulation of cell growth GO:0001558 135 0.039
ribonucleoprotein complex assembly GO:0022618 78 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.038
carbohydrate derivative biosynthetic process GO:1901137 207 0.037
nucleotide excision repair GO:0006289 31 0.037
Yeast
apoptotic signaling pathway GO:0097190 268 0.036
covalent chromatin modification GO:0016569 254 0.036
protein modification by small protein conjugation GO:0032446 342 0.035
regulation of dna templated transcription initiation GO:2000142 9 0.035
Yeast
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.035
chordate embryonic development GO:0043009 34 0.034
negative regulation of intracellular signal transduction GO:1902532 183 0.034
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.032
secretion GO:0046903 254 0.032
microtubule organizing center organization GO:0031023 62 0.031
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.031
mapk cascade GO:0000165 288 0.030
positive regulation of nucleoside metabolic process GO:0045979 186 0.029
cytoplasmic transport GO:0016482 379 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
Rat
sperm egg recognition GO:0035036 3 0.029
positive regulation of phosphorylation GO:0042327 394 0.028
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.028
regulation of membrane potential GO:0042391 95 0.028
ovulation cycle GO:0042698 9 0.028
rna splicing GO:0008380 131 0.027
spindle assembly involved in mitosis GO:0090307 12 0.027
regulation of protein catabolic process GO:0042176 155 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
negative regulation of proteolysis GO:0045861 132 0.027
reproductive process GO:0022414 106 0.026
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
double strand break repair GO:0006302 101 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
response to wounding GO:0009611 168 0.025
positive regulation of dna templated transcription initiation GO:2000144 5 0.024
Yeast
negative regulation of phosphate metabolic process GO:0045936 267 0.024
oligodendrocyte development GO:0014003 6 0.024
membrane hyperpolarization GO:0060081 1 0.024
regulation of t cell activation GO:0050863 77 0.024
protein processing GO:0016485 226 0.023
regulation of mrna splicing via spliceosome GO:0048024 32 0.023
meiosis i GO:0007127 4 0.023
intracellular protein transport GO:0006886 270 0.023
regulation of mitochondrion organization GO:0010821 54 0.023
establishment of protein localization to organelle GO:0072594 172 0.022
regulation of nucleocytoplasmic transport GO:0046822 98 0.022
mitotic spindle organization GO:0007052 27 0.022
regulation of nf kappab import into nucleus GO:0042345 22 0.022
positive regulation of protein catabolic process GO:0045732 75 0.021
regulation of mrna processing GO:0050684 48 0.021
oocyte differentiation GO:0009994 2 0.021
single organism reproductive process GO:0044702 98 0.021
Worm
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.021
protein localization to organelle GO:0033365 280 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
protein modification by small protein removal GO:0070646 92 0.019
mitotic nuclear division GO:0007067 119 0.019
Worm
exit from mitosis GO:0010458 10 0.019
secretion by cell GO:0032940 226 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
response to peptide GO:1901652 65 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.018
gonad development GO:0008406 34 0.018
Worm
posttranscriptional gene silencing GO:0016441 25 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.018
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
cellular response to decreased oxygen levels GO:0036294 51 0.018
positive regulation of growth GO:0045927 58 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
negative regulation of protein transport GO:0051224 75 0.017
single organism cellular localization GO:1902580 332 0.017
cell development GO:0048468 328 0.017
cell growth GO:0016049 160 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
maintenance of location GO:0051235 112 0.017
positive regulation of cell death GO:0010942 263 0.017
protein maturation GO:0051604 233 0.017
nitrogen compound transport GO:0071705 191 0.017
regulation of protein transport GO:0051223 213 0.016
molting cycle GO:0042303 28 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.015
female gonad development GO:0008585 10 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
protein import GO:0017038 130 0.015
regulation of cell development GO:0060284 161 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
Rat
regulation of response to external stimulus GO:0032101 222 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
Rat
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.015
trna metabolic process GO:0006399 35 0.014
double strand break repair via nonhomologous end joining GO:0006303 10 0.014
atp catabolic process GO:0006200 157 0.014
Rat
er associated misfolded protein catabolic process GO:0071712 1 0.014
cellular response to hypoxia GO:0071456 51 0.014
muscle contraction GO:0006936 73 0.014
response to hormone GO:0009725 175 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.013
negative regulation of response to dna damage stimulus GO:2001021 33 0.013
cellular amine metabolic process GO:0044106 41 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
ossification GO:0001503 121 0.013
regulation of cellular response to stress GO:0080135 244 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
Rat
regulation of protein localization to nucleus GO:1900180 85 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.012
negative regulation of intracellular transport GO:0032387 60 0.012
spindle assembly GO:0051225 29 0.012
regulation of translation GO:0006417 89 0.012
oligodendrocyte differentiation GO:0048709 7 0.012
amine metabolic process GO:0009308 44 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
sex differentiation GO:0007548 45 0.012
Worm
response to nitrogen compound GO:1901698 184 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
protein localization to nucleus GO:0034504 136 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
regulation of exit from mitosis GO:0007096 6 0.011
negative regulation of intracellular protein transport GO:0090317 42 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.010
purine containing compound catabolic process GO:0072523 411 0.010
Rat
multicellular organismal reproductive process GO:0048609 40 0.010
non recombinational repair GO:0000726 14 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010

PSMC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
usher syndrome DOID:0050439 12 0.200