Homo sapiens

0 known processes

PSMC6

proteasome (prosome, macropain) 26S subunit, ATPase, 6

(Aliases: MGC12520,CADP44,P44,p42,SUG2)

PSMC6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.998
Yeast
regulation of proteasomal protein catabolic process GO:0061136 87 0.996
cellular protein catabolic process GO:0044257 261 0.995
Yeast
modification dependent protein catabolic process GO:0019941 209 0.994
Yeast
cellular macromolecule catabolic process GO:0044265 380 0.991
Yeast
proteasomal protein catabolic process GO:0010498 176 0.988
Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.968
Yeast
post embryonic development GO:0009791 2 0.967
Worm
proteasome regulatory particle assembly GO:0070682 2 0.967
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.964
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.963
cellular macromolecular complex assembly GO:0034622 324 0.963
Yeast
ubiquitin dependent protein catabolic process GO:0006511 206 0.954
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.954
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.945
Yeast
multicellular organismal aging GO:0010259 3 0.878
Worm
dna templated transcription initiation GO:0006352 35 0.872
Yeast
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.836
Yeast
proteasome assembly GO:0043248 7 0.773
Yeast
mitotic cell cycle GO:0000278 326 0.717
blastocyst development GO:0001824 3 0.674
spindle elongation GO:0051231 4 0.672
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.643
Yeast
cellular protein complex assembly GO:0043623 188 0.606
Yeast
regulation of proteolysis GO:0030162 293 0.596
chromatin modification GO:0016568 298 0.593
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.587
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.558
protein catabolic process GO:0030163 325 0.557
Yeast
regulation of cell cycle GO:0051726 393 0.482
protein modification by small protein conjugation GO:0032446 342 0.479
regulation of cellular protein catabolic process GO:1903362 96 0.462
mitotic cell cycle process GO:1903047 286 0.451
microtubule based process GO:0007017 210 0.434
microtubule cytoskeleton organization GO:0000226 176 0.432
regulation of cellular component biogenesis GO:0044087 281 0.432
Yeast
nuclear division GO:0000280 128 0.420
regulation of protein complex assembly GO:0043254 147 0.381
Yeast
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.379
regulation of mitotic cell cycle GO:0007346 189 0.377
determination of adult lifespan GO:0008340 2 0.372
Worm
aging GO:0007568 66 0.358
Worm
mitotic nuclear division GO:0007067 119 0.349
positive regulation of cellular catabolic process GO:0031331 284 0.317
double strand break repair via nonhomologous end joining GO:0006303 10 0.310
purine nucleotide catabolic process GO:0006195 405 0.304
ribonucleoside triphosphate metabolic process GO:0009199 412 0.289
regulation of protein catabolic process GO:0042176 155 0.271
protein dna complex assembly GO:0065004 64 0.268
Yeast
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.259
Yeast
positive regulation of peptidase activity GO:0010952 88 0.225
protein deubiquitination GO:0016579 79 0.224
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.223
regulation of mitosis GO:0007088 63 0.218
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.215
embryo development GO:0009790 123 0.205
Worm
purine nucleoside monophosphate catabolic process GO:0009128 158 0.202
regulation of protein ubiquitination GO:0031396 95 0.194
spermatid development GO:0007286 4 0.191
mitotic sister chromatid separation GO:0051306 18 0.184
atp metabolic process GO:0046034 176 0.168
spindle assembly GO:0051225 29 0.167
organelle assembly GO:0070925 176 0.164
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.159
Yeast
chromosome separation GO:0051304 23 0.150
double strand break repair GO:0006302 101 0.149
mitotic sister chromatid segregation GO:0000070 53 0.148
organelle fission GO:0048285 149 0.147
protein dna complex subunit organization GO:0071824 80 0.146
Yeast
positive regulation of proteolysis GO:0045862 142 0.144
regulation of kinase activity GO:0043549 314 0.142
spindle organization GO:0007051 53 0.138
regulation of peptidase activity GO:0052547 180 0.138
spermatid differentiation GO:0048515 4 0.137
metaphase anaphase transition of cell cycle GO:0044784 21 0.135
chromatin organization GO:0006325 351 0.131
secretion by cell GO:0032940 226 0.124
nucleoside catabolic process GO:0009164 408 0.119
nucleoside monophosphate catabolic process GO:0009125 159 0.119
oogenesis GO:0048477 2 0.115
positive regulation of endopeptidase activity GO:0010950 84 0.115
embryo development ending in birth or egg hatching GO:0009792 34 0.114
Worm
purine ribonucleotide catabolic process GO:0009154 404 0.112
signal transduction by phosphorylation GO:0023014 297 0.111
negative regulation of cell death GO:0060548 345 0.109
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.108
multicellular organism reproduction GO:0032504 42 0.102
non recombinational repair GO:0000726 14 0.101
regulation of cell cycle process GO:0010564 266 0.101
negative regulation of programmed cell death GO:0043069 321 0.098
female gamete generation GO:0007292 2 0.097
purine containing compound catabolic process GO:0072523 411 0.096
purine nucleoside triphosphate metabolic process GO:0009144 412 0.095
negative regulation of phosphorus metabolic process GO:0010563 267 0.093
nucleotide catabolic process GO:0009166 408 0.092
regulation of cell division GO:0051302 116 0.089
apoptotic mitochondrial changes GO:0008637 57 0.089
positive regulation of protein catabolic process GO:0045732 75 0.088
regulation of chromosome segregation GO:0051983 44 0.088
positive regulation of phosphorylation GO:0042327 394 0.087
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.087
Yeast
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.083
regulation of transferase activity GO:0051338 355 0.082
mitotic spindle organization GO:0007052 27 0.080
covalent chromatin modification GO:0016569 254 0.080
purine nucleoside catabolic process GO:0006152 398 0.080
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.079
positive regulation of catabolic process GO:0009896 310 0.079
protein secretion GO:0009306 98 0.078
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.078
apoptotic signaling pathway GO:0097190 268 0.076
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
regulation of mapk cascade GO:0043408 262 0.074
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.074
negative regulation of apoptotic process GO:0043066 316 0.074
microtubule organizing center organization GO:0031023 62 0.072
cell division GO:0051301 168 0.072
negative regulation of protein metabolic process GO:0051248 391 0.069
negative regulation of phosphorylation GO:0042326 174 0.068
regulation of nuclear division GO:0051783 65 0.066
ribonucleoside catabolic process GO:0042454 406 0.065
nucleoside triphosphate catabolic process GO:0009143 394 0.065
purine ribonucleoside catabolic process GO:0046130 398 0.064
ribonucleoside triphosphate catabolic process GO:0009203 391 0.062
dna repair GO:0006281 198 0.060
Yeast
regulation of protein serine threonine kinase activity GO:0071900 179 0.059
chordate embryonic development GO:0043009 34 0.058
reproduction GO:0000003 63 0.054
Worm
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.054
Yeast
regulation of apoptotic signaling pathway GO:2001233 175 0.054
organophosphate catabolic process GO:0046434 430 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.049
negative regulation of proteolysis GO:0045861 132 0.049
purine ribonucleoside metabolic process GO:0046128 437 0.049
protein ubiquitination GO:0016567 314 0.048
negative regulation of catalytic activity GO:0043086 335 0.047
chromosome segregation GO:0007059 114 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
protein polymerization GO:0051258 71 0.045
positive regulation of cell cycle GO:0045787 140 0.044
regulation of protein kinase activity GO:0045859 289 0.044
mapk cascade GO:0000165 288 0.044
glycosyl compound catabolic process GO:1901658 413 0.043
regulation of cellular response to stress GO:0080135 244 0.043
behavior GO:0007610 112 0.043
nucleocytoplasmic transport GO:0006913 176 0.042
protein k63 linked deubiquitination GO:0070536 21 0.041
regulation of cell growth GO:0001558 135 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
secretion GO:0046903 254 0.040
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.039
positive regulation of protein complex assembly GO:0031334 86 0.039
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.039
negative regulation of organelle organization GO:0010639 126 0.039
negative regulation of protein processing GO:0010955 142 0.038
molting cycle GO:0042303 28 0.038
regulation of response to dna damage stimulus GO:2001020 94 0.036
regulation of protein localization GO:0032880 296 0.035
mitotic spindle elongation GO:0000022 4 0.035
positive regulation of cell projection organization GO:0031346 64 0.034
ribonucleoside monophosphate metabolic process GO:0009161 187 0.034
negative regulation of cellular component organization GO:0051129 235 0.034
protein maturation GO:0051604 233 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.033
regulation of endopeptidase activity GO:0052548 170 0.033
ossification GO:0001503 121 0.033
osteoblast differentiation GO:0001649 92 0.032
regulation of chromosome organization GO:0033044 103 0.032
epithelium development GO:0060429 227 0.031
purine nucleoside monophosphate metabolic process GO:0009126 186 0.030
protein modification by small protein removal GO:0070646 92 0.029
ribonucleoside monophosphate catabolic process GO:0009158 158 0.029
negative regulation of response to wounding GO:1903035 47 0.028
negative regulation of peptidase activity GO:0010466 91 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
developmental process involved in reproduction GO:0003006 66 0.025
rrna metabolic process GO:0016072 40 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
negative regulation of mapk cascade GO:0043409 56 0.025
regulation of mitotic sister chromatid segregation GO:0033047 27 0.024
signal transduction in response to dna damage GO:0042770 57 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
maintenance of protein location in cell GO:0032507 56 0.024
positive regulation of cellular protein catabolic process GO:1903364 37 0.023
negative regulation of endopeptidase activity GO:0010951 84 0.023
protein o linked glycosylation GO:0006493 21 0.022
reproductive structure development GO:0048608 55 0.022
meiotic chromosome segregation GO:0045132 4 0.022
growth GO:0040007 202 0.021
monoubiquitinated histone deubiquitination GO:0035521 3 0.021
negative regulation of cellular protein catabolic process GO:1903363 38 0.021
regulation of growth GO:0040008 165 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.021
cell growth GO:0016049 160 0.020
mitotic cell cycle phase transition GO:0044772 162 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.018
signal transduction by p53 class mediator GO:0072331 72 0.018
trna metabolic process GO:0006399 35 0.017
glycerophospholipid metabolic process GO:0006650 84 0.017
epithelial cell differentiation GO:0030855 141 0.017
sister chromatid segregation GO:0000819 54 0.017
nervous system development GO:0007399 293 0.017
Fly
cellular amine metabolic process GO:0044106 41 0.017
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.016
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
cellular ketone metabolic process GO:0042180 80 0.016
sex differentiation GO:0007548 45 0.016
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.016
regulation of mitotic sister chromatid separation GO:0010965 27 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
spermatogenesis GO:0007283 22 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.016
positive regulation of nervous system development GO:0051962 54 0.016
phosphatidylinositol biosynthetic process GO:0006661 25 0.016
histone deubiquitination GO:0016578 16 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
Yeast
positive regulation of cell development GO:0010720 92 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
protein methylation GO:0006479 74 0.015
regulation of meiosis GO:0040020 3 0.014
cell cycle phase transition GO:0044770 173 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
Yeast
mitochondrial fission GO:0000266 14 0.014
regulation of cellular respiration GO:0043457 4 0.014
negative regulation of immune system process GO:0002683 136 0.014
atp catabolic process GO:0006200 157 0.013
positive regulation of cell growth GO:0030307 48 0.013
maintenance of protein location GO:0045185 57 0.013
regulation of sister chromatid segregation GO:0033045 27 0.012
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
ncrna metabolic process GO:0034660 108 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of protein ubiquitination GO:0031398 53 0.012
centrosome organization GO:0051297 58 0.012
multi organism reproductive process GO:0044703 54 0.011
cell cell signaling GO:0007267 155 0.011
nitrogen compound transport GO:0071705 191 0.011
glycoprotein metabolic process GO:0009100 110 0.011
nuclear transport GO:0051169 179 0.011
system process GO:0003008 349 0.011
negative regulation of intracellular protein transport GO:0090317 42 0.010
dna conformation change GO:0071103 113 0.010
regulation of cellular amine metabolic process GO:0033238 11 0.010
regulation of gene expression epigenetic GO:0040029 73 0.010
negative regulation of protein maturation GO:1903318 142 0.010
rna processing GO:0006396 255 0.010
amine metabolic process GO:0009308 44 0.010
regulation of protein processing GO:0070613 150 0.010

PSMC6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.018
inherited metabolic disorder DOID:655 242 0.018