Homo sapiens

0 known processes

PSMD7

proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

(Aliases: Rpn8,S12,MOV34,P40)

PSMD7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.999
proteasome regulatory particle assembly GO:0070682 2 0.998
proteasomal protein catabolic process GO:0010498 176 0.900
nucleotide excision repair GO:0006289 31 0.892
dna templated transcription initiation GO:0006352 35 0.886
regulation of peptidase activity GO:0052547 180 0.836
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.826
cellular protein catabolic process GO:0044257 261 0.818
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.815
proteasome assembly GO:0043248 7 0.807
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.802
ubiquitin dependent protein catabolic process GO:0006511 206 0.789
modification dependent protein catabolic process GO:0019941 209 0.767
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.744
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.742
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.742
cellular macromolecular complex assembly GO:0034622 324 0.740
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.714
modification dependent macromolecule catabolic process GO:0043632 212 0.688
positive regulation of peptidase activity GO:0010952 88 0.681
protein catabolic process GO:0030163 325 0.642
blastocyst development GO:0001824 3 0.627
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.605
regulation of proteasomal protein catabolic process GO:0061136 87 0.582
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.555
protein deubiquitination GO:0016579 79 0.524
post embryonic development GO:0009791 2 0.519
Worm
determination of adult lifespan GO:0008340 2 0.485
Worm
regulation of protein complex assembly GO:0043254 147 0.433
multicellular organismal aging GO:0010259 3 0.407
Worm
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.406
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.394
positive regulation of endopeptidase activity GO:0010950 84 0.392
mitotic spindle elongation GO:0000022 4 0.385
Fly
spindle elongation GO:0051231 4 0.381
Fly
cellular response to dna damage stimulus GO:0006974 379 0.363
mitotic cell cycle process GO:1903047 286 0.362
Fly
apoptotic mitochondrial changes GO:0008637 57 0.321
negative regulation of peptidase activity GO:0010466 91 0.309
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.305
regulation of proteolysis GO:0030162 293 0.275
regulation of endopeptidase activity GO:0052548 170 0.271
negative regulation of endopeptidase activity GO:0010951 84 0.271
positive regulation of protein complex assembly GO:0031334 86 0.262
purine nucleoside monophosphate catabolic process GO:0009128 158 0.261
protein k63 linked deubiquitination GO:0070536 21 0.252
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.247
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.230
cellular macromolecule catabolic process GO:0044265 380 0.216
protein deglycosylation GO:0006517 2 0.198
purine ribonucleotide catabolic process GO:0009154 404 0.177
positive regulation of phosphorylation GO:0042327 394 0.173
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.173
release of cytochrome c from mitochondria GO:0001836 35 0.172
protein modification by small protein removal GO:0070646 92 0.168
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.157
positive regulation of cellular component biogenesis GO:0044089 158 0.156
cellular protein complex assembly GO:0043623 188 0.153
spermatid development GO:0007286 4 0.149
positive regulation of protein catabolic process GO:0045732 75 0.148
regulation of dna templated transcription initiation GO:2000142 9 0.144
protein modification by small protein conjugation GO:0032446 342 0.143
negative regulation of cellular component organization GO:0051129 235 0.140
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.127
positive regulation of cellular component organization GO:0051130 376 0.125
nuclear division GO:0000280 128 0.124
positive regulation of protein kinase activity GO:0045860 190 0.122
lens development in camera type eye GO:0002088 2 0.120
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.118
positive regulation of kinase activity GO:0033674 204 0.117
positive regulation of protein phosphorylation GO:0001934 313 0.117
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.117
regulation of cellular protein catabolic process GO:1903362 96 0.115
regulation of protein ubiquitination GO:0031396 95 0.113
regulation of locomotion GO:0040012 329 0.111
regulation of mitochondrion organization GO:0010821 54 0.109
regulation of kinase activity GO:0043549 314 0.108
apoptotic signaling pathway GO:0097190 268 0.108
regulation of behavior GO:0050795 82 0.106
regulation of cell growth GO:0001558 135 0.103
spermatid differentiation GO:0048515 4 0.103
chromatin modification GO:0016568 298 0.101
regulation of cell cycle GO:0051726 393 0.098
negative regulation of proteolysis GO:0045861 132 0.095
negative regulation of transport GO:0051051 176 0.095
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.093
dna repair GO:0006281 198 0.092
secretion by cell GO:0032940 226 0.090
signal transduction by phosphorylation GO:0023014 297 0.085
nucleoside phosphate catabolic process GO:1901292 412 0.085
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.083
regulation of apoptotic signaling pathway GO:2001233 175 0.083
oogenesis GO:0048477 2 0.083
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.082
positive regulation of proteolysis GO:0045862 142 0.081
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.081
mitochondrion organization GO:0007005 156 0.080
protein secretion GO:0009306 98 0.080
regulation of mapk cascade GO:0043408 262 0.076
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.075
protein localization to nucleus GO:0034504 136 0.075
nervous system development GO:0007399 293 0.074
Fly
positive regulation of hydrolase activity GO:0051345 331 0.073
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.072
protein ubiquitination GO:0016567 314 0.072
regulation of cellular component biogenesis GO:0044087 281 0.071
protein dna complex subunit organization GO:0071824 80 0.070
chromosome separation GO:0051304 23 0.070
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.070
metaphase anaphase transition of cell cycle GO:0044784 21 0.069
negative regulation of phosphorylation GO:0042326 174 0.068
cell division GO:0051301 168 0.067
mitotic cell cycle GO:0000278 326 0.067
Fly
purine nucleotide catabolic process GO:0006195 405 0.064
ribonucleoside catabolic process GO:0042454 406 0.062
regulation of mitotic cell cycle GO:0007346 189 0.062
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.062
regulation of transferase activity GO:0051338 355 0.061
maintenance of protein location in cell GO:0032507 56 0.060
negative regulation of protein transport GO:0051224 75 0.060
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
organelle fission GO:0048285 149 0.059
regulation of protein serine threonine kinase activity GO:0071900 179 0.059
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.057
negative regulation of phosphate metabolic process GO:0045936 267 0.057
regulation of protein catabolic process GO:0042176 155 0.056
mitotic sister chromatid segregation GO:0000070 53 0.054
peptide transport GO:0015833 74 0.054
mapk cascade GO:0000165 288 0.053
regulation of nf kappab import into nucleus GO:0042345 22 0.051
nucleocytoplasmic transport GO:0006913 176 0.051
negative regulation of hydrolase activity GO:0051346 182 0.050
purine nucleoside catabolic process GO:0006152 398 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.049
negative regulation of phosphorus metabolic process GO:0010563 267 0.049
regulation of cell division GO:0051302 116 0.049
monoubiquitinated histone deubiquitination GO:0035521 3 0.049
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.048
cell growth GO:0016049 160 0.048
protein dna complex assembly GO:0065004 64 0.045
ribonucleoside monophosphate metabolic process GO:0009161 187 0.045
ribonucleotide catabolic process GO:0009261 405 0.045
negative regulation of protein import into nucleus GO:0042308 30 0.044
epithelium development GO:0060429 227 0.044
signal transduction in response to dna damage GO:0042770 57 0.044
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.044
chemical homeostasis GO:0048878 306 0.043
regulation of protein import into nucleus GO:0042306 78 0.043
nucleoside monophosphate catabolic process GO:0009125 159 0.043
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.043
nucleoside triphosphate catabolic process GO:0009143 394 0.043
protein targeting to nucleus GO:0044744 104 0.042
monoubiquitinated protein deubiquitination GO:0035520 6 0.042
eye development GO:0001654 42 0.042
negative regulation of mitochondrion organization GO:0010823 22 0.042
positive regulation of dna templated transcription initiation GO:2000144 5 0.042
lens fiber cell differentiation GO:0070306 2 0.042
positive regulation of cellular catabolic process GO:0031331 284 0.041
negative regulation of protein localization to nucleus GO:1900181 34 0.041
i kappab kinase nf kappab signaling GO:0007249 166 0.041
positive regulation of catabolic process GO:0009896 310 0.040
mitochondrial fission GO:0000266 14 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.040
microtubule based process GO:0007017 210 0.040
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
amide transport GO:0042886 76 0.040
negative regulation of catalytic activity GO:0043086 335 0.040
purine containing compound catabolic process GO:0072523 411 0.039
regulation of cell cycle process GO:0010564 266 0.039
positive regulation of cell growth GO:0030307 48 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
chromatin organization GO:0006325 351 0.039
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.038
positive regulation of protein ubiquitination GO:0031398 53 0.038
protein processing GO:0016485 226 0.037
negative regulation of intracellular signal transduction GO:1902532 183 0.037
nucleoside catabolic process GO:0009164 408 0.037
glycosyl compound catabolic process GO:1901658 413 0.036
epithelial cell differentiation GO:0030855 141 0.036
cytoplasmic sequestering of protein GO:0051220 12 0.036
protein maturation GO:0051604 233 0.036
regulation of inclusion body assembly GO:0090083 13 0.036
maintenance of location GO:0051235 112 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
ribonucleoside monophosphate catabolic process GO:0009158 158 0.035
regulation of protein maturation GO:1903317 150 0.035
negative regulation of mapk cascade GO:0043409 56 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
negative regulation of protein metabolic process GO:0051248 391 0.034
molting cycle GO:0042303 28 0.034
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.034
regulation of protein kinase activity GO:0045859 289 0.033
aging GO:0007568 66 0.032
Worm
recombinational repair GO:0000725 50 0.032
regulation of chemotaxis GO:0050920 74 0.032
atp catabolic process GO:0006200 157 0.032
rna interference GO:0016246 4 0.032
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.032
maintenance of location in cell GO:0051651 62 0.032
dna templated transcription elongation GO:0006354 25 0.031
secretion GO:0046903 254 0.031
positive regulation of cellular protein catabolic process GO:1903364 37 0.031
regulation of protein localization to nucleus GO:1900180 85 0.030
regulation of mitosis GO:0007088 63 0.030
peroxisome organization GO:0007031 28 0.030
reproduction GO:0000003 63 0.030
Worm
regulation of transcription from rna polymerase i promoter GO:0006356 10 0.030
telencephalon development GO:0021537 17 0.029
regulation of response to external stimulus GO:0032101 222 0.029
myeloid dendritic cell differentiation GO:0043011 3 0.028
positive regulation of transferase activity GO:0051347 227 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
negative regulation of protein processing GO:0010955 142 0.028
embryo development GO:0009790 123 0.027
Worm
negative regulation of protein maturation GO:1903318 142 0.027
peroxisome fission GO:0016559 10 0.027
regulation of nuclear division GO:0051783 65 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
regulation of cellular response to stress GO:0080135 244 0.026
atp metabolic process GO:0046034 176 0.026
negative regulation of apoptotic signaling pathway GO:2001234 97 0.026
nucleotide catabolic process GO:0009166 408 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
regulation of response to dna damage stimulus GO:2001020 94 0.026
regulation of growth GO:0040008 165 0.026
double strand break repair via homologous recombination GO:0000724 50 0.025
single organism cellular localization GO:1902580 332 0.025
negative regulation of transcription factor import into nucleus GO:0042992 17 0.025
growth GO:0040007 202 0.025
positive regulation of cell cycle GO:0045787 140 0.025
mitotic nuclear division GO:0007067 119 0.024
primary neural tube formation GO:0014020 3 0.024
single organism nuclear import GO:1902593 104 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.024
regulation of protein processing GO:0070613 150 0.024
chromosome segregation GO:0007059 114 0.024
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.024
cellular ketone metabolic process GO:0042180 80 0.024
immunoglobulin secretion GO:0048305 1 0.024
nf kappab import into nucleus GO:0042348 22 0.023
maintenance of protein location GO:0045185 57 0.023
regulation of peptide transport GO:0090087 62 0.023
rrna metabolic process GO:0016072 40 0.023
ossification GO:0001503 121 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.022
double strand break repair GO:0006302 101 0.022
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
Fly
sensory organ development GO:0007423 52 0.022
amine metabolic process GO:0009308 44 0.022
cytoplasmic sequestering of nf kappab GO:0007253 7 0.021
signal transduction by p53 class mediator GO:0072331 72 0.021
negative regulation of intracellular transport GO:0032387 60 0.021
negative regulation of intracellular protein transport GO:0090317 42 0.021
ncrna metabolic process GO:0034660 108 0.020
cell activation GO:0001775 213 0.020
ventricular system development GO:0021591 1 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
negative regulation of response to dna damage stimulus GO:2001021 33 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
negative regulation of organelle organization GO:0010639 126 0.020
female gamete generation GO:0007292 2 0.020
multicellular organism reproduction GO:0032504 42 0.019
cellular amine metabolic process GO:0044106 41 0.019
nuclear import GO:0051170 106 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
interspecies interaction between organisms GO:0044419 156 0.019
microtubule organizing center organization GO:0031023 62 0.019
regulation of transcription factor import into nucleus GO:0042990 39 0.018
protein import GO:0017038 130 0.018
non recombinational repair GO:0000726 14 0.018
regulation of signal transduction by p53 class mediator GO:1901796 26 0.018
lung alveolus development GO:0048286 4 0.017
neurogenesis GO:0022008 169 0.017
Fly
chemotaxis GO:0006935 157 0.017
negative regulation of cytoplasmic transport GO:1903650 46 0.017
myeloid dendritic cell activation GO:0001773 4 0.017
rna catabolic process GO:0006401 71 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
osteoblast differentiation GO:0001649 92 0.016
organophosphate catabolic process GO:0046434 430 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
double strand break repair via nonhomologous end joining GO:0006303 10 0.016
organelle assembly GO:0070925 176 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
regulation of cell migration GO:0030334 289 0.015
leukocyte differentiation GO:0002521 98 0.015
stem cell differentiation GO:0048863 93 0.015
negative regulation of cell death GO:0060548 345 0.015
embryonic epithelial tube formation GO:0001838 4 0.014
positive regulation of dna templated transcription elongation GO:0032786 18 0.014
chromatin remodeling GO:0006338 55 0.014
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
nuclear transport GO:0051169 179 0.014
brain morphogenesis GO:0048854 1 0.014
neural tube formation GO:0001841 3 0.014
taxis GO:0042330 157 0.014
histone modification GO:0016570 251 0.014
regulation of chromosome organization GO:0033044 103 0.014
protein deneddylation GO:0000338 10 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
neuroblast proliferation GO:0007405 4 0.013
regulation of protein localization GO:0032880 296 0.013
protein k48 linked deubiquitination GO:0071108 19 0.013
regulation of protein targeting GO:1903533 91 0.013
oocyte development GO:0048599 1 0.013
pathway restricted smad protein phosphorylation GO:0060389 38 0.013
meiotic chromosome segregation GO:0045132 4 0.013
regulation of t cell activation GO:0050863 77 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
synaptic transmission GO:0007268 61 0.013
spindle assembly GO:0051225 29 0.013
negative regulation of cellular protein catabolic process GO:1903363 38 0.013
response to cytokine GO:0034097 232 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
camera type eye development GO:0043010 25 0.012
protein homooligomerization GO:0051260 100 0.012
regulation of dna templated transcription elongation GO:0032784 23 0.012
glycoprotein metabolic process GO:0009100 110 0.012
inflammatory response to antigenic stimulus GO:0002437 4 0.012
neural tube closure GO:0001843 3 0.012
negative regulation of release of cytochrome c from mitochondria GO:0090201 11 0.012
dna recombination GO:0006310 77 0.012
er associated misfolded protein catabolic process GO:0071712 1 0.012
regulation of cellular component movement GO:0051270 334 0.012
organ morphogenesis GO:0009887 147 0.012
positive regulation of growth GO:0045927 58 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
regulation of protein transport GO:0051223 213 0.011
locomotory behavior GO:0007626 1 0.011
mitotic sister chromatid separation GO:0051306 18 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
ovarian follicle development GO:0001541 5 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
cell cell signaling GO:0007267 155 0.011
epithelial cell migration GO:0010631 119 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of cell motility GO:2000145 299 0.011
spermatogenesis GO:0007283 22 0.011
meiosis i GO:0007127 4 0.011
negative regulation of developmental process GO:0051093 247 0.010
cell substrate adhesion GO:0031589 132 0.010
regulation of exit from mitosis GO:0007096 6 0.010
regulation of intracellular transport GO:0032386 195 0.010
hemopoiesis GO:0030097 180 0.010
vesicle mediated transport GO:0016192 371 0.010
response to decreased oxygen levels GO:0036293 96 0.010

PSMD7 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.015
hematopoietic system disease DOID:74 100 0.015
central nervous system disease DOID:331 186 0.012
brain disease DOID:936 73 0.012
nervous system disease DOID:863 431 0.012