Homo sapiens

89 known processes

PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

(Aliases: Ki,PA28G,PA28-gamma,REG-GAMMA)

PSME3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 209 0.993
modification dependent macromolecule catabolic process GO:0043632 212 0.990
cellular protein catabolic process GO:0044257 261 0.974
ubiquitin dependent protein catabolic process GO:0006511 206 0.952
protein ubiquitination GO:0016567 314 0.949
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.946
protein modification by small protein conjugation GO:0032446 342 0.938
proteasomal protein catabolic process GO:0010498 176 0.882
cellular macromolecule catabolic process GO:0044265 380 0.861
cytoplasmic transport GO:0016482 379 0.809
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.789
regulation of peptidase activity GO:0052547 180 0.773
protein catabolic process GO:0030163 325 0.768
protein polyubiquitination GO:0000209 110 0.744
positive regulation of peptidase activity GO:0010952 88 0.672
regulation of proteolysis GO:0030162 293 0.657
protein modification by small protein removal GO:0070646 92 0.562
regulation of cell cycle GO:0051726 393 0.559
protein maturation GO:0051604 233 0.526
oogenesis GO:0048477 2 0.504
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.489
positive regulation of hydrolase activity GO:0051345 331 0.458
cellular protein complex assembly GO:0043623 188 0.420
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.413
apoptotic signaling pathway GO:0097190 268 0.413
vesicle mediated transport GO:0016192 371 0.404
response to abiotic stimulus GO:0009628 336 0.399
nuclear division GO:0000280 128 0.365
purine nucleoside triphosphate catabolic process GO:0009146 392 0.342
negative regulation of apoptotic process GO:0043066 316 0.341
protein processing GO:0016485 226 0.339
positive regulation of programmed cell death GO:0043068 249 0.338
cell development GO:0048468 328 0.336
cell division GO:0051301 168 0.331
single organism cellular localization GO:1902580 332 0.330
negative regulation of programmed cell death GO:0043069 321 0.312
intracellular protein transport GO:0006886 270 0.311
cellular macromolecular complex assembly GO:0034622 324 0.295
nucleocytoplasmic transport GO:0006913 176 0.284
transmembrane transport GO:0055085 399 0.279
post embryonic development GO:0009791 2 0.279
nuclear transport GO:0051169 179 0.272
receptor mediated endocytosis GO:0006898 84 0.266
positive regulation of cell differentiation GO:0045597 211 0.262
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.255
negative regulation of protein modification process GO:0031400 200 0.254
membrane organization GO:0061024 292 0.249
protein targeting GO:0006605 187 0.245
cellular amine metabolic process GO:0044106 41 0.239
determination of adult lifespan GO:0008340 2 0.227
cell cell signaling GO:0007267 155 0.223
cellular response to dna damage stimulus GO:0006974 379 0.208
growth GO:0040007 202 0.192
regulation of protein ubiquitination GO:0031396 95 0.190
regulation of cysteine type endopeptidase activity GO:2000116 127 0.185
regulation of mitotic cell cycle GO:0007346 189 0.183
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.180
negative regulation of cellular protein metabolic process GO:0032269 353 0.175
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.163
purine ribonucleotide catabolic process GO:0009154 404 0.153
protein k63 linked ubiquitination GO:0070534 31 0.147
amine metabolic process GO:0009308 44 0.146
oocyte differentiation GO:0009994 2 0.140
positive regulation of endopeptidase activity GO:0010950 84 0.134
positive regulation of transport GO:0051050 336 0.133
positive regulation of cell death GO:0010942 263 0.130
negative regulation of protein metabolic process GO:0051248 391 0.128
posttranscriptional regulation of gene expression GO:0010608 213 0.127
negative regulation of cell proliferation GO:0008285 228 0.123
endocytosis GO:0006897 159 0.121
organelle localization GO:0051640 84 0.120
positive regulation of catabolic process GO:0009896 310 0.118
protein import GO:0017038 130 0.116
regulation of protein maturation GO:1903317 150 0.114
oocyte development GO:0048599 1 0.114
immune response regulating signaling pathway GO:0002764 97 0.112
translation GO:0006412 132 0.110
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.110
mitotic cell cycle GO:0000278 326 0.109
regulation of cellular protein catabolic process GO:1903362 96 0.108
spermatid differentiation GO:0048515 4 0.104
regulation of cell morphogenesis GO:0022604 153 0.099
single organism reproductive process GO:0044702 98 0.097
positive regulation of protein ubiquitination GO:0031398 53 0.096
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.093
enzyme linked receptor protein signaling pathway GO:0007167 303 0.090
multicellular organismal aging GO:0010259 3 0.090
female gamete generation GO:0007292 2 0.089
organophosphate catabolic process GO:0046434 430 0.088
positive regulation of organelle organization GO:0010638 195 0.088
regulation of cell adhesion GO:0030155 166 0.087
protein localization to organelle GO:0033365 280 0.083
establishment of protein localization to organelle GO:0072594 172 0.082
regulation of transferase activity GO:0051338 355 0.081
glycosyl compound catabolic process GO:1901658 413 0.081
single organism membrane organization GO:0044802 268 0.081
positive regulation of apoptotic process GO:0043065 246 0.079
synaptic transmission GO:0007268 61 0.079
hematopoietic or lymphoid organ development GO:0048534 186 0.079
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.077
negative regulation of phosphorylation GO:0042326 174 0.075
negative regulation of protein phosphorylation GO:0001933 140 0.069
multicellular organismal reproductive process GO:0048609 40 0.069
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.068
mitotic nuclear division GO:0007067 119 0.068
spermatid development GO:0007286 4 0.065
locomotory behavior GO:0007626 1 0.063
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.062
purine ribonucleoside metabolic process GO:0046128 437 0.062
actin filament based process GO:0030029 224 0.060
cellular response to cytokine stimulus GO:0071345 181 0.059
establishment of organelle localization GO:0051656 59 0.059
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.058
response to other organism GO:0051707 261 0.058
cellular component morphogenesis GO:0032989 314 0.058
protein targeting to nucleus GO:0044744 104 0.058
regulation of ion transport GO:0043269 189 0.057
cellular amino acid metabolic process GO:0006520 116 0.056
endomembrane system organization GO:0010256 196 0.055
regulation of translation GO:0006417 89 0.055
reproduction GO:0000003 63 0.055
nucleoside triphosphate catabolic process GO:0009143 394 0.053
zymogen activation GO:0031638 70 0.053
regulation of growth GO:0040008 165 0.052
nucleoside phosphate catabolic process GO:1901292 412 0.052
activation of cysteine type endopeptidase activity GO:0097202 57 0.052
negative regulation of proteolysis GO:0045861 132 0.051
behavior GO:0007610 112 0.050
gonad development GO:0008406 34 0.049
regulation of nucleoside metabolic process GO:0009118 209 0.049
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.048
cytokinesis GO:0000910 96 0.048
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
multicellular organism reproduction GO:0032504 42 0.047
nucleus organization GO:0006997 28 0.046
cation transport GO:0006812 331 0.046
mitotic cell cycle process GO:1903047 286 0.046
regulation of purine nucleotide catabolic process GO:0033121 205 0.046
embryo development GO:0009790 123 0.045
negative regulation of cell death GO:0060548 345 0.042
positive regulation of cellular component biogenesis GO:0044089 158 0.041
negative regulation of peptidase activity GO:0010466 91 0.041
negative regulation of cell cycle GO:0045786 193 0.040
protein k48 linked ubiquitination GO:0070936 38 0.039
regulation of mitosis GO:0007088 63 0.039
regulation of immune response GO:0050776 201 0.038
response to cytokine GO:0034097 232 0.038
positive regulation of proteolysis GO:0045862 142 0.038
maintenance of location GO:0051235 112 0.037
positive regulation of cellular catabolic process GO:0031331 284 0.037
reproductive structure development GO:0048608 55 0.037
lipid biosynthetic process GO:0008610 177 0.036
purine nucleotide catabolic process GO:0006195 405 0.036
negative regulation of multicellular organismal process GO:0051241 317 0.036
blood vessel morphogenesis GO:0048514 162 0.036
sex differentiation GO:0007548 45 0.035
meiotic chromosome segregation GO:0045132 4 0.035
regulation of behavior GO:0050795 82 0.034
cell cycle phase transition GO:0044770 173 0.034
regulation of anatomical structure morphogenesis GO:0022603 286 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
positive regulation of gtp catabolic process GO:0033126 166 0.034
regulation of locomotion GO:0040012 329 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.033
protein acylation GO:0043543 138 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.031
embryo development ending in birth or egg hatching GO:0009792 34 0.031
negative regulation of protein maturation GO:1903318 142 0.031
regulation of endopeptidase activity GO:0052548 170 0.030
nervous system development GO:0007399 293 0.030
positive regulation of protein binding GO:0032092 24 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
reproductive system development GO:0061458 56 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
cytokine mediated signaling pathway GO:0019221 109 0.028
negative regulation of endopeptidase activity GO:0010951 84 0.028
chordate embryonic development GO:0043009 34 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.028
positive regulation of immune response GO:0050778 159 0.027
regulation of cell growth GO:0001558 135 0.027
actin cytoskeleton organization GO:0030036 207 0.027
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.027
protein oligomerization GO:0051259 173 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
negative regulation of protein processing GO:0010955 142 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
cell adhesion GO:0007155 325 0.026
myosin filament assembly GO:0031034 2 0.025
regulation of cell differentiation GO:0045595 393 0.025
organelle fission GO:0048285 149 0.025
regulation of intracellular transport GO:0032386 195 0.025
protein deubiquitination GO:0016579 79 0.025
response to radiation GO:0009314 151 0.025
nucleoside catabolic process GO:0009164 408 0.024
cellular response to abiotic stimulus GO:0071214 117 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
defense response GO:0006952 315 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
midbrain development GO:0030901 45 0.023
innate immune response GO:0045087 178 0.023
regulation of protein processing GO:0070613 150 0.023
positive regulation of developmental process GO:0051094 314 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
negative regulation of growth GO:0045926 97 0.022
ras protein signal transduction GO:0007265 73 0.022
i kappab kinase nf kappab signaling GO:0007249 166 0.022
intracellular receptor signaling pathway GO:0030522 104 0.022
single organism nuclear import GO:1902593 104 0.022
chromatin organization GO:0006325 351 0.022
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.022
protein stabilization GO:0050821 64 0.021
regulation of cell division GO:0051302 116 0.021
establishment of ribosome localization GO:0033753 4 0.021
biological adhesion GO:0022610 331 0.021
nucleotide catabolic process GO:0009166 408 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
adult locomotory behavior GO:0008344 1 0.021
regulation of transporter activity GO:0032409 82 0.020
cell growth GO:0016049 160 0.020
protein autoubiquitination GO:0051865 37 0.020
male meiosis GO:0007140 1 0.019
microtubule based process GO:0007017 210 0.019
regulation of protein transport GO:0051223 213 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
aging GO:0007568 66 0.019
dephosphorylation GO:0016311 209 0.018
development of primary sexual characteristics GO:0045137 35 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.018
immune response activating signal transduction GO:0002757 90 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
regulation of response to external stimulus GO:0032101 222 0.018
signal transduction in response to dna damage GO:0042770 57 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.018
activation of immune response GO:0002253 114 0.018
spermatogenesis GO:0007283 22 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.018
positive regulation of protein complex assembly GO:0031334 86 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
positive regulation of cell cycle GO:0045787 140 0.017
protein localization to membrane GO:0072657 160 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of protein catabolic process GO:0042176 155 0.017
sister chromatid segregation GO:0000819 54 0.017
chromosome segregation GO:0007059 114 0.016
developmental process involved in reproduction GO:0003006 66 0.016
nuclear export GO:0051168 69 0.016
organelle assembly GO:0070925 176 0.016
leukocyte differentiation GO:0002521 98 0.016
mitochondrial transport GO:0006839 60 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
protein localization to nucleus GO:0034504 136 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
sexual reproduction GO:0019953 37 0.015
dna damage checkpoint GO:0000077 68 0.015
protein import into nucleus GO:0006606 104 0.015
regulation of chromosome organization GO:0033044 103 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
embryonic morphogenesis GO:0048598 85 0.015
immune response GO:0006955 307 0.015
meiosis i GO:0007127 4 0.014
reproductive process GO:0022414 106 0.014
hemopoiesis GO:0030097 180 0.014
cytokine secretion GO:0050663 64 0.014
cell cycle arrest GO:0007050 71 0.014
mitochondrion organization GO:0007005 156 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.013
central nervous system development GO:0007417 123 0.013
multi organism reproductive process GO:0044703 54 0.013
positive regulation of protein catabolic process GO:0045732 75 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
regulation of protein kinase activity GO:0045859 289 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
regulation of chemotaxis GO:0050920 74 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
dna replication GO:0006260 116 0.013
regulation of protein localization GO:0032880 296 0.012
protein polymerization GO:0051258 71 0.012
blastocyst development GO:0001824 3 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
establishment of nucleus localization GO:0040023 1 0.012
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.012
regulation of transmembrane transport GO:0034762 139 0.012
regulation of defense response GO:0031347 154 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of cell migration GO:0030334 289 0.012
mapk cascade GO:0000165 288 0.011
single organism cell adhesion GO:0098602 179 0.011
taxis GO:0042330 157 0.011
tube development GO:0035295 125 0.011
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.011
positive regulation of peptidyl lysine acetylation GO:2000758 12 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
regulation of innate immune response GO:0045088 97 0.011
cytokine production GO:0001816 247 0.011
response to external biotic stimulus GO:0043207 261 0.011
secretion by cell GO:0032940 226 0.011
regulation of protein binding GO:0043393 66 0.011
histone modification GO:0016570 251 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
protein targeting to mitochondrion GO:0006626 19 0.011
neurogenesis GO:0022008 169 0.011
regulation of cytokine production GO:0001817 232 0.010
lipid localization GO:0010876 106 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
digestive system development GO:0055123 75 0.010

PSME3 disease predictions

Disease DO term ID Size Probability Func Analog Org