|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
4 |
0.999
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.981
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.973
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.965
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.963
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.952
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.949
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.935
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.933
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.912
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.909
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.908
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.901
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.900
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.900
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.896
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.888
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.882
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.830
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.825
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.825
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.781
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.774
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.771
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.765
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.732
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.716
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.716
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.715
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.703
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.670
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.667
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.655
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.651
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.625
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.621
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.617
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.616
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.615
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.610
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.608
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.606
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.605
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.602
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.586
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.584
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.568
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.565
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.563
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.554
|
Human |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.553
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.549
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.541
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.540
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.537
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.525
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.515
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.510
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.507
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.496
|
|
|
|
memory
|
GO:0007613 |
3 |
0.495
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.486
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.463
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.455
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.445
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.442
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.442
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.439
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.426
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.425
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.403
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.401
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.396
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.395
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.395
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.394
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.394
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.393
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.390
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.389
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.383
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.382
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.380
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.379
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.375
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.368
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.361
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.357
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.353
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.347
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.336
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.335
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.331
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.321
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.316
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.310
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.305
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.305
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.304
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.303
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.302
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.302
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.293
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.287
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.280
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.279
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.276
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.274
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.273
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.271
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.266
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.264
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.264
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.260
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.256
|
|
|
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.255
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.249
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.239
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
4 |
0.238
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.235
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.232
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.231
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.231
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.225
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.224
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.223
|
|
|
|
epithelial cell cell adhesion
|
GO:0090136 |
7 |
0.220
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.218
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.214
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.213
|
Human |
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.211
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.206
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.206
|
Human |
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.205
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.203
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.203
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.202
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.202
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.199
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.197
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.194
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.193
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.187
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.184
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.178
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.177
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.175
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.174
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.173
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.173
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.173
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.173
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.164
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.164
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.164
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.163
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.163
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.163
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.163
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.163
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.163
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.162
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.161
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.160
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.160
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.159
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.158
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.156
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.154
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
10 |
0.154
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.152
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.152
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.151
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.150
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.150
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.149
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.148
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.146
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.145
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.142
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.140
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.139
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.139
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.138
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.137
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.136
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.134
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.134
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.132
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.131
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.131
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.130
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.129
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.128
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.128
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.128
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.128
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.127
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.127
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.126
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.126
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.123
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.123
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.123
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.122
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.122
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.121
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.121
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.119
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.119
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
25 |
0.119
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.118
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.117
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.116
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.116
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.115
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.113
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.113
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.113
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.110
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.109
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.108
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.107
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.107
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.107
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.106
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.105
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.104
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.102
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.102
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.100
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.100
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.100
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.099
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.099
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.098
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.098
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.097
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.096
|
|
|
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.096
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.096
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.096
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.095
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.094
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.092
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.092
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.091
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.090
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.090
|
|
|
|
head development
|
GO:0060322 |
108 |
0.089
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.089
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.088
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.088
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.088
|
Human |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.088
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.087
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.087
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.086
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.086
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.085
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.085
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.085
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.083
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.083
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.082
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.082
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.082
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.080
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.080
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.079
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.079
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.078
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.078
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.078
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.077
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.077
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.076
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.075
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.075
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
13 |
0.075
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.074
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.074
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.074
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.074
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.073
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.073
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.073
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.073
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.073
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.073
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.073
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.072
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.072
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.071
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.071
|
|
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.071
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.070
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.070
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.070
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.070
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.069
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.069
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.069
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.069
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.069
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.068
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.068
|
|
|
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.067
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.067
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.066
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.066
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.066
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.066
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.065
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.065
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.065
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.064
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.064
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.064
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.064
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.063
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.063
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.062
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.061
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.061
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.061
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.061
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.060
|
|
|
|
interferon gamma secretion
|
GO:0072643 |
6 |
0.059
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.059
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.059
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.058
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.058
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.058
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.058
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.056
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.056
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.056
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.056
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.056
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.056
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.055
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.055
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.055
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.055
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.054
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.054
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.054
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.054
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.054
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.054
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.054
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.053
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.053
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.053
|
|
|
|
system process
|
GO:0003008 |
349 |
0.052
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.052
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.049
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.049
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.049
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
9 |
0.049
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
15 |
0.049
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.049
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.049
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.048
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.047
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.047
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.047
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.046
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.046
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.046
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.046
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.046
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.045
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.045
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.045
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.045
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.045
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
15 |
0.044
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.044
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.044
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.044
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.044
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.044
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.044
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.043
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.043
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.043
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.043
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.043
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.043
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.043
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.042
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.042
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.042
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.042
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.041
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.041
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.041
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.041
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.041
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.041
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.041
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.041
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.041
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.040
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.040
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.040
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.040
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.040
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.040
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.039
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.039
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.038
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.038
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.038
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.038
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.037
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.037
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.037
|
|
|
|
regulation of mitochondrial depolarization
|
GO:0051900 |
6 |
0.037
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.037
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.037
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.037
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.036
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.036
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.035
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.035
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.035
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.035
|
|
|
|
learning
|
GO:0007612 |
11 |
0.035
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.034
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.034
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
4 |
0.034
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.034
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.034
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.034
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.034
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.034
|
|
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.034
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.033
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.033
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.033
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.032
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.032
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.032
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.032
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.032
|
Human |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.032
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.032
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.032
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.032
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.031
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.031
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.031
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.031
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.030
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.030
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.030
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.030
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.030
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.030
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.030
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.029
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.029
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.029
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.029
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.029
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.028
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.028
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.028
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.028
|
|