Homo sapiens

41 known processes

PTBP2

polypyrimidine tract binding protein 2

(Aliases: FLJ34897,PTBLP,nPTB,nPTB6,PTB,nPTB5,nPTB7,brPTB,nPTB8)

PTBP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oogenesis GO:0048477 2 0.817
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.807
Fly
mrna splicing via spliceosome GO:0000398 89 0.741
Human Mouse
positive regulation of nucleobase containing compound transport GO:0032241 1 0.691
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.611
Human Mouse
regulation of mrna splicing via spliceosome GO:0048024 32 0.609
Human
mrna metabolic process GO:0016071 175 0.570
Human Mouse
rna splicing GO:0008380 131 0.547
rna processing GO:0006396 255 0.505
mrna processing GO:0006397 133 0.504
Human Mouse
regulation of mrna metabolic process GO:1903311 53 0.494
Human
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.491
Fly
regulation of translation GO:0006417 89 0.483
Fly
snrna metabolic process GO:0016073 15 0.464
translation GO:0006412 132 0.432
Fly
female gamete generation GO:0007292 2 0.389
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.283
Fly
cellular divalent inorganic cation homeostasis GO:0072503 128 0.218
microtubule based process GO:0007017 210 0.208
Fly
sex determination GO:0007530 3 0.185
negative regulation of protein metabolic process GO:0051248 391 0.171
Fly
mating GO:0007618 1 0.161
positive regulation of transport GO:0051050 336 0.159
regulation of rna splicing GO:0043484 62 0.159
regulation of cell differentiation GO:0045595 393 0.149
Human
negative regulation of mrna metabolic process GO:1903312 15 0.138
Human
oocyte differentiation GO:0009994 2 0.137
Fly
stress activated protein kinase signaling cascade GO:0031098 94 0.135
negative regulation of rna splicing GO:0033119 15 0.129
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.122
Human
rna stabilization GO:0043489 18 0.112
regulation of cellular response to stress GO:0080135 244 0.111
Fly
regulation of cell division GO:0051302 116 0.106
cellular homeostasis GO:0019725 196 0.102
low density lipoprotein particle clearance GO:0034383 8 0.100
signal transduction by phosphorylation GO:0023014 297 0.099
organelle assembly GO:0070925 176 0.097
nuclear transport GO:0051169 179 0.095
mitotic nuclear division GO:0007067 119 0.094
cellular component morphogenesis GO:0032989 314 0.090
small molecule biosynthetic process GO:0044283 157 0.087
actin filament based process GO:0030029 224 0.087
rna splicing via transesterification reactions GO:0000375 90 0.086
Human Mouse
mitotic cell cycle process GO:1903047 286 0.086
nuclear export GO:0051168 69 0.085
cytoplasmic transport GO:0016482 379 0.084
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.084
oocyte development GO:0048599 1 0.080
Fly
cellular chemical homeostasis GO:0055082 180 0.073
regulation of protein serine threonine kinase activity GO:0071900 179 0.073
regulation of nucleocytoplasmic transport GO:0046822 98 0.072
axoneme assembly GO:0035082 3 0.071
3 utr mediated mrna stabilization GO:0070935 8 0.067
single organism cellular localization GO:1902580 332 0.067
regulation of muscle cell differentiation GO:0051147 31 0.066
Human
central nervous system development GO:0007417 123 0.065
negative regulation of developmental process GO:0051093 247 0.064
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.064
Fly
cation homeostasis GO:0055080 189 0.064
nucleocytoplasmic transport GO:0006913 176 0.063
chromatin organization GO:0006325 351 0.063
spermatid differentiation GO:0048515 4 0.062
Fly
multicellular organismal reproductive process GO:0048609 40 0.060
Fly
negative regulation of mrna processing GO:0050686 12 0.058
Human
positive regulation of translational initiation GO:0045948 7 0.058
positive regulation of translation GO:0045727 35 0.058
cellular metal ion homeostasis GO:0006875 146 0.057
spermatid development GO:0007286 4 0.057
Fly
post embryonic development GO:0009791 2 0.054
Fly
amine metabolic process GO:0009308 44 0.054
intracellular receptor signaling pathway GO:0030522 104 0.053
regulation of definitive erythrocyte differentiation GO:0010724 2 0.051
cellular amino acid metabolic process GO:0006520 116 0.051
chemical homeostasis GO:0048878 306 0.050
cellular component assembly involved in morphogenesis GO:0010927 73 0.049
inorganic ion transmembrane transport GO:0098660 231 0.049
secretion by cell GO:0032940 226 0.048
3 utr mediated mrna destabilization GO:0061158 1 0.048
stress activated mapk cascade GO:0051403 93 0.048
ion homeostasis GO:0050801 230 0.046
regulation of myeloid cell differentiation GO:0045637 81 0.046
positive regulation of multi organism process GO:0043902 56 0.045
trna 3 end processing GO:0042780 3 0.044
negative regulation of cell differentiation GO:0045596 171 0.043
Human
immune response GO:0006955 307 0.042
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.042
system process GO:0003008 349 0.041
cell morphogenesis GO:0000902 296 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.040
positive regulation of intracellular transport GO:0032388 104 0.038
transmembrane transport GO:0055085 399 0.038
positive regulation of kinase activity GO:0033674 204 0.038
growth GO:0040007 202 0.038
positive regulation of protein kinase activity GO:0045860 190 0.037
anterior posterior axis specification GO:0009948 2 0.037
chemotaxis GO:0006935 157 0.036
ameboidal type cell migration GO:0001667 135 0.036
positive regulation of cellular component organization GO:0051130 376 0.036
neuromuscular junction development GO:0007528 3 0.035
glial cell migration GO:0008347 4 0.035
plasma lipoprotein particle clearance GO:0034381 16 0.035
rna interference GO:0016246 4 0.035
alternative mrna splicing via spliceosome GO:0000380 27 0.035
Human
translational initiation GO:0006413 48 0.034
memory GO:0007613 3 0.033
dosage compensation GO:0007549 3 0.033
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.032
regulation of intracellular transport GO:0032386 195 0.032
positive regulation of immune system process GO:0002684 283 0.032
cellular ketone metabolic process GO:0042180 80 0.031
regulation of cytoplasmic transport GO:1903649 149 0.030
mapk cascade GO:0000165 288 0.030
positive regulation of map kinase activity GO:0043406 80 0.030
cellular ion homeostasis GO:0006873 168 0.030
i kappab kinase nf kappab signaling GO:0007249 166 0.030
regulation of calcium ion dependent exocytosis GO:0017158 8 0.030
regulation of cell cycle process GO:0010564 266 0.030
positive regulation of response to external stimulus GO:0032103 88 0.029
axon regeneration GO:0031103 1 0.029
mrna stabilization GO:0048255 18 0.029
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
cell development GO:0048468 328 0.029
Fly
protein targeting GO:0006605 187 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
positive regulation of cell activation GO:0050867 81 0.028
innate immune response GO:0045087 178 0.028
cell activation GO:0001775 213 0.028
regulation of response to dna damage stimulus GO:2001020 94 0.028
Fly
regulation of response to external stimulus GO:0032101 222 0.028
regulation of growth GO:0040008 165 0.028
regulation of mitotic cell cycle GO:0007346 189 0.027
regulation of vesicle mediated transport GO:0060627 130 0.027
epithelial cell migration GO:0010631 119 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
positive regulation of transferase activity GO:0051347 227 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.026
regulation of cell activation GO:0050865 125 0.026
cilium assembly GO:0042384 63 0.026
jnk cascade GO:0007254 80 0.026
regulation of secretion by cell GO:1903530 177 0.026
notch signaling pathway GO:0007219 31 0.026
Fly
positive regulation of protein phosphorylation GO:0001934 313 0.026
taxis GO:0042330 157 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.025
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
response to abiotic stimulus GO:0009628 336 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
maintenance of location GO:0051235 112 0.025
chromatin modification GO:0016568 298 0.025
secretion GO:0046903 254 0.024
regulation of defense response GO:0031347 154 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
positive regulation of rna export from nucleus GO:0046833 1 0.024
primary neural tube formation GO:0014020 3 0.024
behavioral response to ethanol GO:0048149 2 0.024
rho protein signal transduction GO:0007266 26 0.024
rna transport GO:0050658 39 0.024
response to fungus GO:0009620 4 0.024
signal release GO:0023061 70 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.023
protein oligomerization GO:0051259 173 0.022
endocytosis GO:0006897 159 0.022
tube closure GO:0060606 3 0.022
blastoderm segmentation GO:0007350 2 0.022
chromatin remodeling GO:0006338 55 0.022
cation transport GO:0006812 331 0.022
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.022
positive regulation of cell division GO:0051781 59 0.022
regulation of mapk cascade GO:0043408 262 0.022
positive regulation of exocytosis GO:0045921 35 0.022
cellular response to oxygen containing compound GO:1901701 276 0.021
positive regulation of cytoplasmic transport GO:1903651 82 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
nitrogen compound transport GO:0071705 191 0.021
regulation of protein processing GO:0070613 150 0.021
regulation of mrna processing GO:0050684 48 0.021
Human
protein modification by small protein conjugation GO:0032446 342 0.021
sexual reproduction GO:0019953 37 0.021
Fly
synaptic transmission cholinergic GO:0007271 2 0.020
limbic system development GO:0021761 3 0.020
response to axon injury GO:0048678 1 0.020
axis elongation GO:0003401 4 0.020
epithelium migration GO:0090132 119 0.020
positive regulation of defense response GO:0031349 87 0.020
convergent extension involved in gastrulation GO:0060027 1 0.020
positive regulation of phosphorylation GO:0042327 394 0.019
response to external biotic stimulus GO:0043207 261 0.019
regulation of map kinase activity GO:0043405 108 0.019
positive regulation of calcium ion dependent exocytosis GO:0045956 6 0.019
regulation of hormone secretion GO:0046883 57 0.019
motor neuron axon guidance GO:0008045 2 0.019
actin cytoskeleton organization GO:0030036 207 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.019
regulation of lipid transport by positive regulation of transcription from rna polymerase ii promoter GO:0072369 2 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
head development GO:0060322 108 0.019
regulation of rna stability GO:0043487 23 0.019
neurological system process GO:0050877 163 0.019
cell projection morphogenesis GO:0048858 129 0.018
positive regulation of stress activated mapk cascade GO:0032874 60 0.018
receptor mediated endocytosis GO:0006898 84 0.018
defense response to fungus GO:0050832 4 0.018
calcium ion homeostasis GO:0055074 122 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.018
regulation of plasma lipoprotein particle levels GO:0097006 32 0.018
regulation of cell cycle GO:0051726 393 0.018
neurotransmitter secretion GO:0007269 4 0.018
cilium morphogenesis GO:0060271 75 0.018
single organism reproductive process GO:0044702 98 0.017
Fly
peptide hormone secretion GO:0030072 50 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
positive regulation of nuclear division GO:0051785 27 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
regulation of multi organism process GO:0043900 157 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of peptidyl serine phosphorylation GO:0033135 50 0.017
organelle fission GO:0048285 149 0.017
modification of morphology or physiology of other organism GO:0035821 43 0.017
positive regulation of organelle organization GO:0010638 195 0.017
long term memory GO:0007616 2 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
defense response to other organism GO:0098542 129 0.017
regulation of cell motility GO:2000145 299 0.016
mrna destabilization GO:0061157 1 0.016
neural tube closure GO:0001843 3 0.016
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.016
regulation of stress activated mapk cascade GO:0032872 84 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
carboxylic acid biosynthetic process GO:0046394 97 0.016
tripartite regional subdivision GO:0007351 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
axonogenesis GO:0007409 31 0.016
rna catabolic process GO:0006401 71 0.016
biological adhesion GO:0022610 331 0.016
regulation of transmembrane transport GO:0034762 139 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
Fly
trna processing GO:0008033 23 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
regulation of cell adhesion GO:0030155 166 0.015
protein modification by small protein removal GO:0070646 92 0.015
tissue migration GO:0090130 119 0.015
cell fate determination GO:0001709 3 0.015
regulation of kinase activity GO:0043549 314 0.015
associative learning GO:0008306 1 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
cellular cation homeostasis GO:0030003 163 0.015
cytokine production GO:0001816 247 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
protein catabolic process GO:0030163 325 0.015
response to nitrogen compound GO:1901698 184 0.015
negative regulation of hydrolase activity GO:0051346 182 0.014
positive regulation of developmental process GO:0051094 314 0.014
cellular protein catabolic process GO:0044257 261 0.014
neuron differentiation GO:0030182 138 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
cilium organization GO:0044782 68 0.014
somatic stem cell division GO:0048103 1 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of mitosis GO:0007088 63 0.014
negative regulation of protein modification process GO:0031400 200 0.014
positive regulation of jnk cascade GO:0046330 52 0.014
cell projection assembly GO:0030031 126 0.014
segmentation GO:0035282 4 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
nucleobase containing compound transport GO:0015931 51 0.014
defense response to bacterium GO:0042742 63 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
cytoplasmic translational initiation GO:0002183 6 0.014
vesicle mediated transport GO:0016192 371 0.014
sister chromatid segregation GO:0000819 54 0.014
convergent extension GO:0060026 1 0.013
purine containing compound catabolic process GO:0072523 411 0.013
termination of rna polymerase ii transcription GO:0006369 1 0.013
regulation of peptide secretion GO:0002791 42 0.013
cell projection organization GO:0030030 252 0.013
cellular response to lipid GO:0071396 127 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
regulation of nuclear division GO:0051783 65 0.013
nervous system development GO:0007399 293 0.013
positive regulation of jun kinase activity GO:0043507 23 0.013
response to other organism GO:0051707 261 0.013
male genitalia development GO:0030539 1 0.013
response to tumor necrosis factor GO:0034612 76 0.013
regulation of protein maturation GO:1903317 150 0.013
regulation of translational initiation GO:0006446 24 0.013
muscle cell differentiation GO:0042692 63 0.013
Human
multi organism reproductive process GO:0044703 54 0.013
Fly
intracellular protein transport GO:0006886 270 0.013
low density lipoprotein receptor particle metabolic process GO:0032799 8 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
negative regulation of translation GO:0017148 37 0.013
Fly
response to cytokine GO:0034097 232 0.013
regulation of dna binding GO:0051101 37 0.013
defense response GO:0006952 315 0.013
axon development GO:0061564 34 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
detection of stimulus GO:0051606 85 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
Mouse
regulation of synaptic plasticity GO:0048167 3 0.013
regulation of insulin secretion GO:0050796 33 0.013
nucleus localization GO:0051647 1 0.013
cellular protein complex assembly GO:0043623 188 0.013
single organism cell adhesion GO:0098602 179 0.013
small gtpase mediated signal transduction GO:0007264 78 0.012
response to biotic stimulus GO:0009607 276 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
brain development GO:0007420 97 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cation transmembrane transport GO:0098655 238 0.012
regulation of cellular component movement GO:0051270 334 0.012
regulation of cytokine production GO:0001817 232 0.012
negative regulation of cytokine production GO:0001818 82 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
myosin filament assembly GO:0031034 2 0.012
cell chemotaxis GO:0060326 112 0.012
hindbrain development GO:0030902 3 0.012
regulation of protein transport GO:0051223 213 0.012
cell junction assembly GO:0034329 67 0.012
rhythmic process GO:0048511 31 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
negative regulation of transferase activity GO:0051348 124 0.012
cellular amine metabolic process GO:0044106 41 0.012
regulation of protein kinase activity GO:0045859 289 0.012
regulation of hormone levels GO:0010817 125 0.012
myeloid cell differentiation GO:0030099 117 0.012
metal ion transport GO:0030001 272 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
regulation of peptide hormone secretion GO:0090276 41 0.012
intestinal epithelial structure maintenance GO:0060729 1 0.012
positive regulation of mitosis GO:0045840 25 0.012
nuclear import GO:0051170 106 0.012
neural tube formation GO:0001841 3 0.012
regulation of immune effector process GO:0002697 91 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
circadian behavior GO:0048512 2 0.011
organic acid biosynthetic process GO:0016053 97 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
neural crest cell development GO:0014032 3 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
regulation of protein complex assembly GO:0043254 147 0.011
somitogenesis GO:0001756 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.011
ossification GO:0001503 121 0.011
regulation of behavior GO:0050795 82 0.011
pattern specification process GO:0007389 43 0.011
Fly
ras protein signal transduction GO:0007265 73 0.011
regulation of jnk cascade GO:0046328 73 0.011
gamete generation GO:0007276 25 0.011
Fly
cell cell signaling GO:0007267 155 0.011
neuron development GO:0048666 113 0.011
regulation of axon extension involved in axon guidance GO:0048841 2 0.011
regulation of peptidase activity GO:0052547 180 0.011
calcium ion transmembrane transport GO:0070588 76 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
positive regulation of secretion GO:0051047 116 0.011
proteasomal protein catabolic process GO:0010498 176 0.010
regulation of cardiac muscle hypertrophy in response to stress GO:1903242 2 0.010
regulation of neuron differentiation GO:0045664 70 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010

PTBP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.043
nervous system disease DOID:863 431 0.043
neurodegenerative disease DOID:1289 102 0.026
disease of metabolism DOID:0014667 295 0.016
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
carbohydrate metabolism disease DOID:0050013 32 0.014
acquired metabolic disease DOID:0060158 58 0.014