Homo sapiens

190 known processes

PTGIS

prostaglandin I2 (prostacyclin) synthase

(Aliases: CYP8A1,MGC126860,PTGI,PGIS,CYP8,MGC126858)

PTGIS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
enzyme linked receptor protein signaling pathway GO:0007167 303 0.832
cardiovascular system development GO:0072358 262 0.796
regulation of cellular component movement GO:0051270 334 0.786
regulation of locomotion GO:0040012 329 0.773
circulatory system development GO:0072359 262 0.771
small gtpase mediated signal transduction GO:0007264 78 0.713
regulation of cell migration GO:0030334 289 0.702
positive regulation of locomotion GO:0040017 186 0.645
vasculature development GO:0001944 181 0.644
cellular response to growth factor stimulus GO:0071363 197 0.617
blood vessel development GO:0001568 172 0.615
response to wounding GO:0009611 168 0.604
regulation of anatomical structure morphogenesis GO:0022603 286 0.592
system process GO:0003008 349 0.556
mapk cascade GO:0000165 288 0.548
cell adhesion GO:0007155 325 0.539
actin filament based process GO:0030029 224 0.517
regulation of cell differentiation GO:0045595 393 0.504
single organism cell adhesion GO:0098602 179 0.486
regulation of system process GO:0044057 101 0.479
positive regulation of protein phosphorylation GO:0001934 313 0.477
cellular response to endogenous stimulus GO:0071495 336 0.476
negative regulation of multicellular organismal process GO:0051241 317 0.472
biological adhesion GO:0022610 331 0.467
negative regulation of locomotion GO:0040013 118 0.465
regulation of cellular ketone metabolic process GO:0010565 50 0.457
Human
regulation of mapk cascade GO:0043408 262 0.447
response to lipid GO:0033993 206 0.446
negative regulation of developmental process GO:0051093 247 0.442
response to growth factor GO:0070848 205 0.423
regulation of cellular amine metabolic process GO:0033238 11 0.421
ras protein signal transduction GO:0007265 73 0.420
amine metabolic process GO:0009308 44 0.418
actin cytoskeleton organization GO:0030036 207 0.407
positive regulation of developmental process GO:0051094 314 0.399
regulation of cell motility GO:2000145 299 0.388
muscle contraction GO:0006936 73 0.388
anatomical structure formation involved in morphogenesis GO:0048646 284 0.387
cellular ketone metabolic process GO:0042180 80 0.376
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.375
organophosphate catabolic process GO:0046434 430 0.373
urogenital system development GO:0001655 65 0.372
regulation of cell adhesion GO:0030155 166 0.371
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.354
hemostasis GO:0007599 76 0.348
ossification GO:0001503 121 0.341
regulation of body fluid levels GO:0050878 99 0.340
ribonucleotide catabolic process GO:0009261 405 0.339
tube development GO:0035295 125 0.335
negative regulation of cellular component movement GO:0051271 106 0.330
blood circulation GO:0008015 113 0.326
positive regulation of cellular amine metabolic process GO:0033240 7 0.325
positive regulation of cell proliferation GO:0008284 301 0.322
purine ribonucleotide catabolic process GO:0009154 404 0.322
negative regulation of cell death GO:0060548 345 0.321
response to oxygen containing compound GO:1901700 369 0.319
Human
positive regulation of cell migration GO:0030335 172 0.317
circulatory system process GO:0003013 113 0.313
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.309
purine nucleoside catabolic process GO:0006152 398 0.307
wound healing GO:0042060 115 0.303
cell development GO:0048468 328 0.292
kidney development GO:0001822 53 0.290
regulation of cytoskeleton organization GO:0051493 177 0.287
blood coagulation GO:0007596 76 0.282
muscle system process GO:0003012 81 0.271
metal ion transport GO:0030001 272 0.270
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.262
muscle structure development GO:0061061 98 0.260
glycosyl compound catabolic process GO:1901658 413 0.260
regulation of transferase activity GO:0051338 355 0.257
purine nucleoside triphosphate catabolic process GO:0009146 392 0.251
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.248
cellular component morphogenesis GO:0032989 314 0.247
regulation of cellular component biogenesis GO:0044087 281 0.242
nervous system development GO:0007399 293 0.241
cellular amino acid metabolic process GO:0006520 116 0.237
rho protein signal transduction GO:0007266 26 0.235
positive regulation of cell motility GO:2000147 177 0.234
osteoblast differentiation GO:0001649 92 0.234
purine nucleotide catabolic process GO:0006195 405 0.232
negative regulation of cell motility GO:2000146 104 0.229
cation transport GO:0006812 331 0.223
positive regulation of cellular component movement GO:0051272 181 0.221
positive regulation of protein kinase activity GO:0045860 190 0.220
epithelial cell migration GO:0010631 119 0.220
ribonucleoside catabolic process GO:0042454 406 0.218
cellular amine metabolic process GO:0044106 41 0.216
chemical homeostasis GO:0048878 306 0.216
Human
chemotaxis GO:0006935 157 0.214
regulation of actin filament based process GO:0032970 141 0.214
positive regulation of cellular component organization GO:0051130 376 0.213
positive regulation of mapk cascade GO:0043410 190 0.213
regulation of ras protein signal transduction GO:0046578 155 0.213
single organismal cell cell adhesion GO:0016337 148 0.212
organ morphogenesis GO:0009887 147 0.211
negative regulation of cell migration GO:0030336 102 0.210
positive regulation of hydrolase activity GO:0051345 331 0.208
regulation of protein kinase activity GO:0045859 289 0.207
peptidyl tyrosine modification GO:0018212 170 0.207
purine containing compound catabolic process GO:0072523 411 0.205
purine ribonucleoside catabolic process GO:0046130 398 0.203
nucleoside phosphate catabolic process GO:1901292 412 0.201
cellular divalent inorganic cation homeostasis GO:0072503 128 0.200
actin filament organization GO:0007015 128 0.200
regulation of cellular amino acid metabolic process GO:0006521 6 0.198
renal system development GO:0072001 63 0.198
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.194
positive regulation of transport GO:0051050 336 0.194
purine ribonucleoside metabolic process GO:0046128 437 0.193
coagulation GO:0050817 78 0.192
nucleoside triphosphate catabolic process GO:0009143 394 0.191
erk1 and erk2 cascade GO:0070371 104 0.190
cell morphogenesis GO:0000902 296 0.188
regulation of small gtpase mediated signal transduction GO:0051056 156 0.182
g protein coupled receptor signaling pathway GO:0007186 207 0.181
regulation of actin cytoskeleton organization GO:0032956 116 0.178
nucleoside catabolic process GO:0009164 408 0.178
regulation of epithelial cell proliferation GO:0050678 113 0.177
ribonucleoside triphosphate metabolic process GO:0009199 412 0.177
positive regulation of cell adhesion GO:0045785 84 0.177
positive regulation of odontogenesis GO:0042482 3 0.176
lipid biosynthetic process GO:0008610 177 0.176
nucleotide catabolic process GO:0009166 408 0.176
regulation of hormone levels GO:0010817 125 0.176
cyclic nucleotide metabolic process GO:0009187 82 0.173
signal transduction by phosphorylation GO:0023014 297 0.172
cell substrate adhesion GO:0031589 132 0.167
blood vessel morphogenesis GO:0048514 162 0.167
lipid metabolic process GO:0006629 381 0.166
epithelium migration GO:0090132 119 0.163
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.163
metal ion homeostasis GO:0055065 169 0.160
ribonucleoside triphosphate catabolic process GO:0009203 391 0.158
positive regulation of epithelial cell proliferation GO:0050679 65 0.158
angiogenesis GO:0001525 147 0.156
regulation of gtp catabolic process GO:0033124 180 0.156
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.154
negative regulation of apoptotic process GO:0043066 316 0.154
positive regulation of phosphorylation GO:0042327 394 0.153
positive regulation of transferase activity GO:0051347 227 0.151
hematopoietic or lymphoid organ development GO:0048534 186 0.151
tissue morphogenesis GO:0048729 96 0.150
branch elongation involved in ureteric bud branching GO:0060681 2 0.149
nucleoside triphosphate metabolic process GO:0009141 422 0.148
bone mineralization GO:0030282 34 0.148
regulation of cellular response to stress GO:0080135 244 0.146
regulation of purine nucleotide metabolic process GO:1900542 264 0.146
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.146
skeletal system development GO:0001501 79 0.143
regulation of response to external stimulus GO:0032101 222 0.142
small molecule biosynthetic process GO:0044283 157 0.142
tissue migration GO:0090130 119 0.140
regulation of angiogenesis GO:0045765 92 0.140
regulation of kinase activity GO:0043549 314 0.138
peptidyl tyrosine phosphorylation GO:0018108 170 0.138
ion homeostasis GO:0050801 230 0.138
muscle cell proliferation GO:0033002 35 0.136
divalent metal ion transport GO:0070838 152 0.136
regulation of nucleotide catabolic process GO:0030811 205 0.136
endothelial cell migration GO:0043542 86 0.135
response to organic cyclic compound GO:0014070 204 0.135
ameboidal type cell migration GO:0001667 135 0.133
negative regulation of cellular component organization GO:0051129 235 0.131
negative regulation of cell proliferation GO:0008285 228 0.131
epithelium development GO:0060429 227 0.130
regulation of odontogenesis GO:0042481 4 0.129
regulation of response to wounding GO:1903034 101 0.129
morphogenesis of a branching structure GO:0001763 21 0.129
ion transmembrane transport GO:0034220 338 0.125
cell cell signaling GO:0007267 155 0.125
secretion GO:0046903 254 0.123
positive regulation of cell differentiation GO:0045597 211 0.122
defense response GO:0006952 315 0.121
regulation of intracellular transport GO:0032386 195 0.120
transmembrane transport GO:0055085 399 0.120
taxis GO:0042330 157 0.119
gtp metabolic process GO:0046039 239 0.119
calcium ion transport GO:0006816 147 0.119
morphogenesis of an epithelium GO:0002009 60 0.119
positive regulation of nucleotide metabolic process GO:0045981 230 0.118
immune system development GO:0002520 195 0.115
cellular metal ion homeostasis GO:0006875 146 0.115
cellular ion homeostasis GO:0006873 168 0.115
regulation of cell cycle GO:0051726 393 0.115
negative regulation of cell differentiation GO:0045596 171 0.114
cardiac muscle tissue development GO:0048738 39 0.112
lung alveolus development GO:0048286 4 0.110
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.110
response to cytokine GO:0034097 232 0.110
negative regulation of neutrophil chemotaxis GO:0090024 2 0.110
purine nucleoside triphosphate metabolic process GO:0009144 412 0.109
positive regulation of cellular catabolic process GO:0031331 284 0.109
heart development GO:0007507 95 0.109
dna replication GO:0006260 116 0.108
positive regulation of organelle organization GO:0010638 195 0.107
regulation of purine nucleotide catabolic process GO:0033121 205 0.107
secretion by cell GO:0032940 226 0.106
negative regulation of protein metabolic process GO:0051248 391 0.106
connective tissue development GO:0061448 39 0.105
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.105
kidney epithelium development GO:0072073 25 0.104
divalent inorganic cation transport GO:0072511 158 0.104
regulation of erk1 and erk2 cascade GO:0070372 99 0.104
positive regulation of programmed cell death GO:0043068 249 0.103
negative regulation of transport GO:0051051 176 0.102
cytoplasmic transport GO:0016482 379 0.102
cytokine production GO:0001816 247 0.102
regulation of nucleotide metabolic process GO:0006140 269 0.102
cellular cation homeostasis GO:0030003 163 0.102
regulation of cell cell adhesion GO:0022407 57 0.101
negative regulation of programmed cell death GO:0043069 321 0.101
positive regulation of catabolic process GO:0009896 310 0.101
regulation of endothelial cell migration GO:0010594 67 0.101
regulation of secretion GO:0051046 194 0.100
calcium ion homeostasis GO:0055074 122 0.100
growth GO:0040007 202 0.098
cation homeostasis GO:0055080 189 0.098
regulation of peptidase activity GO:0052547 180 0.097
regulation of behavior GO:0050795 82 0.096
behavior GO:0007610 112 0.095
positive regulation of nucleotide catabolic process GO:0030813 185 0.095
negative regulation of epithelial cell migration GO:0010633 38 0.095
alcohol metabolic process GO:0006066 114 0.094
negative regulation of phosphate metabolic process GO:0045936 267 0.094
regulation of nucleoside metabolic process GO:0009118 209 0.094
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.093
positive regulation of cytoskeleton organization GO:0051495 83 0.093
bmp signaling pathway GO:0030509 49 0.092
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.092
intracellular protein transport GO:0006886 270 0.092
cell morphogenesis involved in differentiation GO:0000904 144 0.092
cellular response to organic cyclic compound GO:0071407 127 0.092
regulation of vasculature development GO:1901342 97 0.091
regulation of establishment of protein localization GO:0070201 242 0.091
response to abiotic stimulus GO:0009628 336 0.091
positive regulation of cellular component biogenesis GO:0044089 158 0.090
negative regulation of testosterone biosynthetic process GO:2000225 1 0.089
regulation of cytoplasmic transport GO:1903649 149 0.089
negative regulation of cell adhesion GO:0007162 64 0.089
gtp catabolic process GO:0006184 237 0.089
regulation of chemotaxis GO:0050920 74 0.089
positive regulation of aldosterone metabolic process GO:0032346 2 0.088
positive regulation of nucleoside metabolic process GO:0045979 186 0.088
regulation of protein serine threonine kinase activity GO:0071900 179 0.087
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.087
platelet activation GO:0030168 44 0.086
response to hormone GO:0009725 175 0.086
endothelial cell proliferation GO:0001935 65 0.085
response to nitrogen compound GO:1901698 184 0.085
positive regulation of kinase activity GO:0033674 204 0.085
negative regulation of male gonad development GO:2000019 1 0.085
positive regulation of behavior GO:0048520 60 0.083
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.083
regulation of stress activated mapk cascade GO:0032872 84 0.083
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.083
regulation of cell development GO:0060284 161 0.083
vesicle mediated transport GO:0016192 371 0.083
response to other organism GO:0051707 261 0.082
regulation of cell activation GO:0050865 125 0.082
inorganic ion transmembrane transport GO:0098660 231 0.082
response to external biotic stimulus GO:0043207 261 0.081
cell activation GO:0001775 213 0.081
jnk cascade GO:0007254 80 0.080
biomineral tissue development GO:0031214 39 0.079
positive regulation of immune system process GO:0002684 283 0.079
regulation of muscle system process GO:0090257 53 0.078
homotypic cell cell adhesion GO:0034109 47 0.078
positive regulation of gtpase activity GO:0043547 166 0.078
carbohydrate derivative biosynthetic process GO:1901137 207 0.078
positive regulation of apoptotic process GO:0043065 246 0.078
regulation of protein localization GO:0032880 296 0.077
positive regulation of cytokine production GO:0001819 167 0.077
cell type specific apoptotic process GO:0097285 125 0.077
nucleoside monophosphate catabolic process GO:0009125 159 0.075
cellular homeostasis GO:0019725 196 0.075
Human
regulation of cytokine production GO:0001817 232 0.074
regulation of ossification GO:0030278 58 0.073
positive regulation of gtp catabolic process GO:0033126 166 0.073
organ formation GO:0048645 3 0.073
mesenchymal cell differentiation GO:0048762 52 0.072
sequestering of metal ion GO:0051238 24 0.072
actin filament based movement GO:0030048 17 0.071
regulation of osteoblast differentiation GO:0045667 38 0.070
guanosine containing compound catabolic process GO:1901069 239 0.070
mitotic cell cycle GO:0000278 326 0.070
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.070
epithelial cell proliferation GO:0050673 128 0.069
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.069
cellular calcium ion homeostasis GO:0006874 117 0.069
organic hydroxy compound metabolic process GO:1901615 147 0.069
Human
muscle tissue development GO:0060537 62 0.068
activation of mapk activity GO:0000187 45 0.068
regulation of epithelial cell migration GO:0010632 93 0.068
epithelial tube morphogenesis GO:0060562 38 0.068
cellular response to nitrogen compound GO:1901699 144 0.067
activation of protein kinase activity GO:0032147 90 0.067
response to alcohol GO:0097305 64 0.067
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.067
cellular lipid metabolic process GO:0044255 303 0.067
regulation of lipid metabolic process GO:0019216 96 0.066
Human
single organism cellular localization GO:1902580 332 0.066
negative regulation of protein phosphorylation GO:0001933 140 0.066
cation transmembrane transport GO:0098655 238 0.066
striated muscle contraction GO:0006941 52 0.065
cytosolic calcium ion homeostasis GO:0051480 89 0.065
response to organonitrogen compound GO:0010243 156 0.064
divalent inorganic cation homeostasis GO:0072507 136 0.063
platelet aggregation GO:0070527 32 0.063
segmentation GO:0035282 4 0.063
negative regulation of cellular protein metabolic process GO:0032269 353 0.063
regulation of blood circulation GO:1903522 59 0.062
negative regulation of intracellular signal transduction GO:1902532 183 0.062
cellular response to oxygen containing compound GO:1901701 276 0.062
Human
positive regulation of vasoconstriction GO:0045907 3 0.062
cell chemotaxis GO:0060326 112 0.061
mitotic cell cycle process GO:1903047 286 0.061
positive regulation of cell death GO:0010942 263 0.061
regulation of blood vessel size GO:0050880 18 0.061
brain development GO:0007420 97 0.061
regulation of protein transport GO:0051223 213 0.061
positive chemotaxis GO:0050918 33 0.061
motor neuron axon guidance GO:0008045 2 0.061
female gamete generation GO:0007292 2 0.061
protein oligomerization GO:0051259 173 0.060
regulation of gtpase activity GO:0043087 180 0.060
embryonic morphogenesis GO:0048598 85 0.059
forelimb morphogenesis GO:0035136 4 0.059
mesonephros development GO:0001823 17 0.059
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.059
regulation of proteolysis GO:0030162 293 0.058
cellular response to cytokine stimulus GO:0071345 181 0.058
vascular process in circulatory system GO:0003018 29 0.058
neuron projection development GO:0031175 106 0.058
purine nucleoside monophosphate metabolic process GO:0009126 186 0.057
purine nucleoside monophosphate catabolic process GO:0009128 158 0.057
locomotory behavior GO:0007626 1 0.057
induction of negative chemotaxis GO:0050929 1 0.057
digestive tract development GO:0048565 75 0.057
positive regulation of endothelial cell migration GO:0010595 39 0.057
positive regulation of angiogenesis GO:0045766 51 0.056
cellular chemical homeostasis GO:0055082 180 0.056
Human
response to steroid hormone GO:0048545 80 0.056
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.056
negative regulation of cell cycle GO:0045786 193 0.055
regulation of homeostatic process GO:0032844 121 0.055
regulation of ion transport GO:0043269 189 0.055
positive regulation of hormone biosynthetic process GO:0046886 4 0.055
positive regulation of protein transport GO:0051222 135 0.054
negative regulation of catalytic activity GO:0043086 335 0.054
head development GO:0060322 108 0.054
negative regulation of vasculature development GO:1901343 43 0.054
camp biosynthetic process GO:0006171 47 0.053
positive regulation of map kinase activity GO:0043406 80 0.053
cell projection organization GO:0030030 252 0.053
apoptotic signaling pathway GO:0097190 268 0.053
smooth muscle cell migration GO:0014909 18 0.053
regeneration GO:0031099 4 0.053
immune response GO:0006955 307 0.052
inorganic cation transmembrane transport GO:0098662 194 0.052
regulation of cell cycle process GO:0010564 266 0.052
striated muscle tissue development GO:0014706 59 0.052
cellular protein complex assembly GO:0043623 188 0.052
atp catabolic process GO:0006200 157 0.052
regulation of leukocyte migration GO:0002685 63 0.052
positive regulation of ras gtpase activity GO:0032320 117 0.051
central nervous system development GO:0007417 123 0.051
neuron development GO:0048666 113 0.051
mesonephric epithelium development GO:0072163 14 0.051
regulation of mitotic cell cycle GO:0007346 189 0.051
regulation of secretion by cell GO:1903530 177 0.051
sprouting angiogenesis GO:0002040 29 0.050
negative regulation of endothelial cell migration GO:0010596 29 0.050
regulation of bmp signaling pathway GO:0030510 27 0.050
regulation of ion homeostasis GO:2000021 73 0.050
regulation of anatomical structure size GO:0090066 101 0.050
response to biotic stimulus GO:0009607 276 0.050
sequestering of calcium ion GO:0051208 17 0.050
protein processing GO:0016485 226 0.050
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.050
post embryonic development GO:0009791 2 0.049
heart process GO:0003015 62 0.049
regulation of leukocyte activation GO:0002694 115 0.049
stress activated protein kinase signaling cascade GO:0031098 94 0.048
heart contraction GO:0060047 62 0.048
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.048
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.048
cellular macromolecular complex assembly GO:0034622 324 0.048
positive regulation of chemotaxis GO:0050921 57 0.047
negative regulation of phosphorus metabolic process GO:0010563 267 0.047
phospholipid metabolic process GO:0006644 99 0.047
regulation of dna metabolic process GO:0051052 153 0.046
regulation of blood coagulation GO:0030193 42 0.046
regulation of map kinase activity GO:0043405 108 0.046
digestive system development GO:0055123 75 0.046
regulation of transmembrane transport GO:0034762 139 0.046
positive regulation of lipid metabolic process GO:0045834 50 0.045
cell growth GO:0016049 160 0.045
retinal ganglion cell axon guidance GO:0031290 2 0.045
regulation of calcium ion transport GO:0051924 79 0.045
cell matrix adhesion GO:0007160 85 0.045
regulation of ion transmembrane transport GO:0034765 132 0.045
cellular response to organonitrogen compound GO:0071417 124 0.045
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.045
regulation of bone mineralization GO:0030500 29 0.045
myeloid leukocyte migration GO:0097529 62 0.044
innate immune response GO:0045087 178 0.044
generation of neurons GO:0048699 152 0.044
mesonephric tubule development GO:0072164 14 0.044
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.044
protein kinase b signaling GO:0043491 69 0.043
mesonephric duct development GO:0072177 3 0.043
sensory perception of pain GO:0019233 4 0.043
positive regulation of osteoblast differentiation GO:0045669 23 0.043
negative regulation of immune system process GO:0002683 136 0.042
regulation of endothelial cell proliferation GO:0001936 56 0.042
regulation of protein import into nucleus GO:0042306 78 0.042
mesenchyme development GO:0060485 59 0.042
negative regulation of response to external stimulus GO:0032102 83 0.042
neurogenesis GO:0022008 169 0.042
regulation of muscle organ development GO:0048634 27 0.042
positive regulation of cytoplasmic transport GO:1903651 82 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
hemopoiesis GO:0030097 180 0.041
negative regulation of cell growth GO:0030308 83 0.041
negative regulation of phosphorylation GO:0042326 174 0.041
protein targeting GO:0006605 187 0.040
protein maturation GO:0051604 233 0.040
gastrulation GO:0007369 51 0.040
regulation of cell growth GO:0001558 135 0.040
regulation of apoptotic signaling pathway GO:2001233 175 0.040
ribonucleoside monophosphate catabolic process GO:0009158 158 0.040
positive regulation of protein kinase b signaling GO:0051897 42 0.040
oogenesis GO:0048477 2 0.040
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.039
maintenance of location GO:0051235 112 0.039
regulation of protein localization to nucleus GO:1900180 85 0.039
regulation of rho protein signal transduction GO:0035023 79 0.039
regulation of cell morphogenesis GO:0022604 153 0.039
embryonic forelimb morphogenesis GO:0035115 4 0.039
membrane organization GO:0061024 292 0.039
reproductive process GO:0022414 106 0.039
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 187 0.039
nucleoside monophosphate metabolic process GO:0009123 191 0.039
regulation of intracellular protein transport GO:0033157 123 0.039
positive regulation of intracellular transport GO:0032388 104 0.038
epithelial cell differentiation GO:0030855 141 0.038
protein import GO:0017038 130 0.038
cellular response to dna damage stimulus GO:0006974 379 0.038
blood vessel endothelial cell migration GO:0043534 42 0.038
negative regulation of androgen biosynthetic process GO:2000180 1 0.038
regulation of leukocyte chemotaxis GO:0002688 46 0.037
positive regulation of endothelial cell proliferation GO:0001938 37 0.037
regulation of metal ion transport GO:0010959 120 0.037
negative regulation of protein modification process GO:0031400 200 0.037
neuron fate commitment GO:0048663 2 0.037
negative regulation of bmp signaling pathway GO:0030514 17 0.037
cardiac muscle cell contraction GO:0086003 4 0.037
negative regulation of organelle organization GO:0010639 126 0.036
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.036
digestive tract morphogenesis GO:0048546 56 0.036
calcium ion transport into cytosol GO:0060402 48 0.036
organophosphate biosynthetic process GO:0090407 163 0.036
blastoderm segmentation GO:0007350 2 0.036
epithelial to mesenchymal transition GO:0001837 48 0.036
actomyosin structure organization GO:0031032 59 0.036
reactive oxygen species metabolic process GO:0072593 75 0.036
multicellular organismal aging GO:0010259 3 0.035
guanosine containing compound metabolic process GO:1901068 244 0.035
cell projection morphogenesis GO:0048858 129 0.035
negative regulation of wound healing GO:0061045 25 0.035
leukocyte migration GO:0050900 107 0.035
nephron development GO:0072006 30 0.035
response to inorganic substance GO:0010035 127 0.034
fatty acid metabolic process GO:0006631 115 0.034
protein targeting to nucleus GO:0044744 104 0.034
camp metabolic process GO:0046058 61 0.034
leukocyte activation GO:0045321 164 0.034
pattern specification process GO:0007389 43 0.034
ribonucleotide biosynthetic process GO:0009260 81 0.034
response to hypoxia GO:0001666 96 0.034
positive regulation of dermatome development GO:0061184 3 0.034
glycerolipid metabolic process GO:0046486 107 0.034
myeloid cell differentiation GO:0030099 117 0.033
positive regulation of ion transport GO:0043270 87 0.033
multicellular organismal metabolic process GO:0044236 34 0.033
protein localization to nucleus GO:0034504 136 0.033

PTGIS disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.332
musculoskeletal system disease DOID:17 223 0.218
heart disease DOID:114 68 0.157
muscular disease DOID:0080000 114 0.069
muscle tissue disease DOID:66 113 0.058
myopathy DOID:423 104 0.037