|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
1.000
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.999
|
Human Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.999
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.999
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.999
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.999
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.999
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.999
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.998
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.998
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.998
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.998
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.998
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.998
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.997
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.997
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.996
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.995
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.995
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.995
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.994
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.994
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.994
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.994
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.994
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.994
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.993
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.993
|
Human Mouse Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.993
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.992
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.992
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.992
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.992
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.992
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.992
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.991
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.991
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.990
|
Human |
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.990
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.990
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.990
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.989
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.989
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.989
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.989
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.988
|
Human Rat |
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.987
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.986
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.986
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.985
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.985
|
Human |
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.985
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.984
|
Human Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.983
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.983
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.982
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.980
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.980
|
Zebrafish |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.980
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.979
|
Human Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.979
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.978
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.978
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.978
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.977
|
Human Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.976
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.974
|
Human Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.974
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.974
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.973
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.973
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.973
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.971
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.971
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.969
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.968
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.967
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.967
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.966
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.965
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.964
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.963
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.963
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.962
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.961
|
Human Mouse |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.960
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.959
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.956
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.955
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.954
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.953
|
Human |
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
6 |
0.952
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.952
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.950
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.949
|
Human Mouse Rat |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.949
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.948
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.947
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.946
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.944
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.943
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.941
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.936
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.933
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.927
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.927
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.925
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.922
|
Human Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.920
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.917
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.912
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.911
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.907
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.901
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.897
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.895
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.894
|
Human Mouse |
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.892
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.891
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.889
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.887
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.887
|
Human Fly |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.881
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.880
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.879
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.877
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.871
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.868
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.865
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.858
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.856
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.848
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.846
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.845
|
Human Rat Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.845
|
Human |
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.843
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.842
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.837
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.823
|
Human Rat |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.820
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.813
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.809
|
Human |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.807
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.806
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.796
|
Human Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.793
|
Fly |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.792
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.792
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.781
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.778
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.775
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.764
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.749
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.740
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.739
|
Human Mouse |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.738
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.727
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.703
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.700
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.699
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.697
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.694
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.691
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.685
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.680
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.679
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
65 |
0.670
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.658
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.653
|
Fly |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.651
|
Human |
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.649
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.627
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.609
|
Human |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.608
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.601
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.599
|
Human |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.597
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.595
|
Mouse |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.594
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.593
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.591
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.589
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.588
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.579
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.575
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.570
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.554
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.552
|
Human Rat |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.543
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.543
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.543
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.541
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.539
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.537
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.537
|
Human Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.535
|
Human |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.534
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.533
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.532
|
Human Mouse Rat |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.529
|
Human Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.526
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.525
|
Rat |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.524
|
Human Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.520
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.518
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.518
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.514
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.513
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.508
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.506
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.505
|
Human Rat |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.501
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.494
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.491
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.486
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.481
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.473
|
Human Rat |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.464
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.453
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.448
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.447
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.444
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.442
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.437
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.436
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.435
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.432
|
Mouse |
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.430
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.429
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.427
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.427
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.421
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.416
|
Mouse Rat Fly |
|
|
tube development
|
GO:0035295 |
125 |
0.416
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.410
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.410
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.409
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.408
|
Zebrafish Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.408
|
Rat |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.407
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.404
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.401
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.401
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.397
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.395
|
Human Rat |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.382
|
Rat |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.377
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.376
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.370
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.368
|
Human Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.367
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.366
|
Human Mouse |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.357
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.356
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.356
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.346
|
Human Mouse Fly |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.345
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.339
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.339
|
Human |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.336
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.336
|
Human Rat |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.335
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.335
|
Rat |
|
|
tissue migration
|
GO:0090130 |
119 |
0.334
|
Human Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.334
|
Rat |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.333
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.332
|
Fly |
|
|
growth
|
GO:0040007 |
202 |
0.328
|
Mouse Rat Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.325
|
Human |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.323
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.323
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.323
|
|
|
|
regulation of arf protein signal transduction
|
GO:0032012 |
1 |
0.322
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.319
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.317
|
Rat |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.312
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.307
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.295
|
Human Rat Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.290
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.288
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.288
|
Human Mouse Rat |
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.285
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.284
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.283
|
Human |
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.262
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.261
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.259
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.257
|
Rat |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.251
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.250
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.246
|
Mouse Fly |
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.244
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.241
|
Human Mouse |
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.237
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.234
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.232
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.227
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.225
|
Human Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.225
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.224
|
Rat |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.223
|
Mouse |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.215
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.214
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.213
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.208
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.208
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.207
|
Zebrafish |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.205
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.202
|
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
15 |
0.202
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.201
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.199
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.197
|
Human Rat |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.196
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.195
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.195
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.195
|
Human Mouse |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.194
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.192
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.189
|
Human Rat |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.187
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.186
|
Rat |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.185
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.185
|
Human Rat |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.184
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.184
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.184
|
Human |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.182
|
Fly |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.178
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.178
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.177
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.176
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.175
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.174
|
Human Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.174
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.169
|
Fly |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.168
|
Human Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.168
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.167
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.163
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.162
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.160
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.159
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.158
|
Human Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.158
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.155
|
Rat |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.155
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.152
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.152
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.151
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.149
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.148
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.148
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.145
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.145
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.144
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.141
|
Human Mouse Rat |
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.141
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.140
|
Human Mouse Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.140
|
Human Rat |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.139
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.138
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.138
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.137
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.135
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.133
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.132
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.132
|
Human Mouse |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.131
|
Rat |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.131
|
Human Rat |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.130
|
Human Mouse Rat |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.129
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.126
|
Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.125
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
6 |
0.124
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.124
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.122
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.120
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.119
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.117
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.115
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.115
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.114
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.113
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.112
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.112
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.111
|
Human Mouse |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.111
|
|
|
|
syncytium formation
|
GO:0006949 |
4 |
0.111
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.111
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.110
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.108
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.108
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.107
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.107
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.107
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.107
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.106
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.104
|
Human |
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.104
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.102
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.102
|
Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.101
|
Mouse |
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.100
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.100
|
Human |
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.100
|
|
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
2 |
0.099
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.099
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.099
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.098
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.098
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.097
|
Human Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.097
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.096
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.096
|
Human Mouse Rat Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.095
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.093
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.093
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.092
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.091
|
|
|
|
positive regulation of epidermal growth factor receptor signaling pathway
|
GO:0045742 |
11 |
0.091
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.091
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.089
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.089
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.088
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.087
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.085
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.085
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.085
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.084
|
Human Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.084
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.084
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.084
|
|
|
|
programmed cell death in response to reactive oxygen species
|
GO:0097468 |
4 |
0.083
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.082
|
Rat |
|
|
oocyte development
|
GO:0048599 |
1 |
0.082
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.081
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.080
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.079
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.078
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.078
|
Rat |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.077
|
Fly |
|
|
cochlea development
|
GO:0090102 |
1 |
0.077
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.077
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.077
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.076
|
Human |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.076
|
Human |
|
|
metanephric nephron tubule morphogenesis
|
GO:0072282 |
1 |
0.075
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.075
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.075
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.074
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.073
|
Human |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.073
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.072
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.072
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.072
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.072
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.072
|
Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.072
|
Human |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.071
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.071
|
Mouse Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.071
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.070
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.070
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.070
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.070
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.069
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.069
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.068
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.068
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.068
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.068
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.067
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.067
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.067
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.067
|
Human Mouse |
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.066
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.066
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.065
|
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.064
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.064
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.064
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.064
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.063
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.063
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.063
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.063
|
Human Mouse |
|
|
lipid localization
|
GO:0010876 |
106 |
0.062
|
|
