|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.953
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.921
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.875
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.855
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.850
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.791
|
Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.772
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.738
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.626
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.619
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.610
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.569
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.560
|
Rat |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.538
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.538
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.531
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.522
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.511
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.509
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.508
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.497
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.472
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.469
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.469
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.466
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.463
|
Human Rat |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.454
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.440
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.429
|
Rat |
|
|
response to peptide
|
GO:1901652 |
65 |
0.428
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.414
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.406
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.404
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.403
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.403
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.392
|
Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.386
|
Rat Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.386
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.385
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.384
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.383
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.377
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.374
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.373
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.370
|
Human Rat |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.368
|
Human Rat |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.366
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.364
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.364
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.357
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.352
|
Rat |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.351
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.351
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.350
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.350
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.347
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.341
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.333
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.331
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.329
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.323
|
Human Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.321
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.316
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.315
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.305
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.302
|
Rat |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.298
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.294
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.288
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.287
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.287
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.278
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.278
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.275
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.271
|
Rat |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.271
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.270
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.264
|
Rat |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.262
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.261
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.260
|
Rat |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.260
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.258
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.256
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.254
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.251
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.250
|
Rat |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.241
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.236
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.235
|
Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.233
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.226
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.223
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.221
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.220
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.219
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.218
|
Rat |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.216
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.215
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.214
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.205
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.205
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.202
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.199
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.195
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.192
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.192
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.191
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.190
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.190
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.190
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.188
|
Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.186
|
Rat |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.184
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.184
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.184
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.183
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.183
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.182
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.182
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.181
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.180
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.179
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.177
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.176
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.169
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.168
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.166
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.165
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.163
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.163
|
Rat |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.162
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.161
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.161
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.160
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.159
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.159
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.159
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.158
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.158
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.157
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.156
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.155
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.155
|
Fly |
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.154
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.152
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.150
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.149
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.148
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.148
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.144
|
|
|
|
phospholipid transport
|
GO:0015914 |
23 |
0.142
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.142
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.140
|
Rat |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.139
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.139
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.137
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.135
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.134
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.132
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.131
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.131
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.129
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.128
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.128
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.128
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.128
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.127
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.127
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.125
|
Rat |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.123
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.122
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.120
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.120
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.120
|
Rat |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.117
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.117
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.117
|
Mouse Rat |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.117
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.116
|
Rat |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.116
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.115
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.115
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.114
|
Mouse |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.112
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.112
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.112
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.111
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.111
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.110
|
Rat |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.108
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.107
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.107
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.107
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.106
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.106
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.106
|
Rat |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.106
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.105
|
Rat |
|
|
b cell activation
|
GO:0042113 |
33 |
0.103
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.102
|
Rat |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.102
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.102
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.101
|
Rat |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.101
|
Rat |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.101
|
Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.100
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.099
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.098
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.098
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.097
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.095
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.095
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.095
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.094
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.093
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.093
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.093
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.092
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.091
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.091
|
Rat |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.090
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.090
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.090
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.090
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.088
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.088
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.087
|
Rat |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.086
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.086
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.084
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.084
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.084
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.082
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.080
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.080
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.080
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.080
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.079
|
Mouse Rat |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.078
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.078
|
Rat |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.078
|
Rat |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.077
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.077
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.077
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.076
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.076
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.076
|
Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.076
|
Rat |
|
|
regulation of extracellular vesicular exosome assembly
|
GO:1903551 |
4 |
0.075
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.075
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.075
|
Mouse |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.074
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.074
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.073
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.073
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.073
|
Human |
|
|
anion transport
|
GO:0006820 |
161 |
0.072
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.072
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.072
|
Mouse Rat |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.071
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.071
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.071
|
Rat |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.071
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.070
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.070
|
Rat |
|
|
organophosphate ester transport
|
GO:0015748 |
32 |
0.070
|
|
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
6 |
0.070
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.070
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.069
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.069
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.068
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.067
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.067
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.067
|
|
|
|
regulation of golgi to plasma membrane protein transport
|
GO:0042996 |
3 |
0.066
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.066
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.066
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.066
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.066
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.065
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.065
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.065
|
|
|
|
regulation of rhodopsin mediated signaling pathway
|
GO:0022400 |
1 |
0.064
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.064
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.064
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.063
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.063
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.063
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.063
|
Mouse Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.062
|
|
|
|
viral budding
|
GO:0046755 |
9 |
0.062
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.062
|
Fly |
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.062
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.062
|
Mouse Rat |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.062
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.061
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.061
|
Fly |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.061
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.061
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.061
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.061
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
11 |
0.061
|
Mouse |
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.060
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.060
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.060
|
Rat |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.060
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.059
|
Human |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.059
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.058
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.057
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.057
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.057
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.056
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.056
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.056
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.055
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.055
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
98 |
0.054
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.054
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.054
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.054
|
|
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
2 |
0.054
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.054
|
Rat Fly |
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.053
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.053
|
|
|
|
negative regulation of lipid catabolic process
|
GO:0050995 |
9 |
0.053
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.053
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.053
|
Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.053
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.052
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.052
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.052
|
Rat |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.052
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.052
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.052
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.051
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.051
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.051
|
Rat |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.051
|
Rat |
|
|
coagulation
|
GO:0050817 |
78 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.050
|
Rat |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.049
|
Mouse |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.049
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.049
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.049
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.048
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.048
|
Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.048
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.048
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.048
|
Human |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.048
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.047
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.047
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.047
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.046
|
Rat |
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.046
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.046
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.046
|
Rat |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.046
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.045
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.045
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.045
|
Fly |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.045
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.045
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.044
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.044
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.044
|
Rat |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.044
|
Mouse Rat |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.044
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.043
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.043
|
Rat |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.043
|
Human |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.043
|
Fly |
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.043
|
Rat |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.043
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.043
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.043
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.043
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.043
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
26 |
0.043
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.042
|
Fly |
|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.042
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.042
|
Mouse Rat |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.042
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.042
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
1 |
0.041
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.041
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.041
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.041
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.040
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.040
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.040
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.040
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.040
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.040
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.040
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.040
|
Rat |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.040
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.039
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.039
|
Rat |
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.039
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.039
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.039
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.039
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.039
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.039
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.039
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.038
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.038
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.038
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.038
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.038
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.038
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.038
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.038
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.038
|
Human |
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.038
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.038
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.038
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.038
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.037
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.037
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.037
|
Rat |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.037
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.037
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.037
|
|
|
|
phototransduction visible light
|
GO:0007603 |
2 |
0.036
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.036
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.036
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.036
|
Human |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.036
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.036
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.035
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.035
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.035
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.035
|
Rat |
|
|
behavior
|
GO:0007610 |
112 |
0.035
|
Mouse |
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.035
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.035
|
Mouse |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.035
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.035
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.035
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.035
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.034
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.034
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.034
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.034
|
|
|
|
positive regulation of extracellular vesicular exosome assembly
|
GO:1903553 |
4 |
0.034
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.034
|
Rat |
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.034
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.034
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.034
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.034
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.034
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.033
|
|
|
|
memory
|
GO:0007613 |
3 |
0.033
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.033
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.033
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.033
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.033
|
Rat |
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.033
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.033
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.033
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.032
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.032
|
|
|
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
9 |
0.032
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.032
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.032
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.032
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.032
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.032
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.031
|
|
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.031
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.031
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.031
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.031
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.031
|
Rat |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.031
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.031
|
|
|
|
golgi to plasma membrane transport
|
GO:0006893 |
21 |
0.031
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.031
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.031
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.031
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.031
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.030
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.030
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.030
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
Rat Fly |
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.030
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.030
|
|
