Homo sapiens

0 known processes

PTMA

prothymosin, alpha

(Aliases: TMSA,MGC104802)

PTMA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.989
nucleosome assembly GO:0006334 50 0.907
nucleosome organization GO:0034728 66 0.664
chromatin modification GO:0016568 298 0.594
regulation of megakaryocyte differentiation GO:0045652 22 0.428
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 2 0.381
chromatin assembly GO:0031497 61 0.355
positive regulation of peptidase activity GO:0010952 88 0.341
regulation of cell differentiation GO:0045595 393 0.339
positive regulation of transport GO:0051050 336 0.277
regulation of establishment of protein localization GO:0070201 242 0.274
protein dna complex assembly GO:0065004 64 0.273
protein dna complex subunit organization GO:0071824 80 0.271
v d j recombination GO:0033151 3 0.250
chromatin organization GO:0006325 351 0.227
positive regulation of cell death GO:0010942 263 0.222
positive regulation of cytoplasmic transport GO:1903651 82 0.203
atp dependent chromatin remodeling GO:0043044 25 0.189
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.181
cellular macromolecular complex assembly GO:0034622 324 0.171
positive regulation of programmed cell death GO:0043068 249 0.171
establishment of ribosome localization GO:0033753 4 0.166
negative regulation of cell growth GO:0030308 83 0.165
chromatin assembly or disassembly GO:0006333 78 0.163
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.162
regulation of intracellular transport GO:0032386 195 0.148
positive regulation of protein transport GO:0051222 135 0.148
positive regulation of developmental process GO:0051094 314 0.146
regulation of protein localization GO:0032880 296 0.136
positive regulation of apoptotic process GO:0043065 246 0.134
regulation of peptidase activity GO:0052547 180 0.131
positive regulation of hydrolase activity GO:0051345 331 0.125
regulation of nuclease activity GO:0032069 11 0.123
positive regulation of erythrocyte differentiation GO:0045648 11 0.120
intracellular protein transport GO:0006886 270 0.116
response to external biotic stimulus GO:0043207 261 0.115
regulation of myeloid cell differentiation GO:0045637 81 0.111
positive regulation of cell proliferation GO:0008284 301 0.110
positive regulation of immune system process GO:0002684 283 0.108
positive regulation of epithelial cell proliferation GO:0050679 65 0.106
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.105
dna integration GO:0015074 3 0.102
dna repair GO:0006281 198 0.100
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.097
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.093
dna ligation involved in dna repair GO:0051103 4 0.090
immune response GO:0006955 307 0.088
negative regulation of cell differentiation GO:0045596 171 0.086
female gamete generation GO:0007292 2 0.084
nuclear export GO:0051168 69 0.078
hemopoiesis GO:0030097 180 0.078
negative regulation of catalytic activity GO:0043086 335 0.078
cytoplasmic transport GO:0016482 379 0.075
positive regulation of proteolysis GO:0045862 142 0.074
negative regulation of developmental process GO:0051093 247 0.073
megakaryocyte differentiation GO:0030219 25 0.072
multi organism cellular process GO:0044764 156 0.072
vesicle mediated transport GO:0016192 371 0.070
regeneration GO:0031099 4 0.069
positive regulation of intracellular transport GO:0032388 104 0.069
regulation of cell cycle process GO:0010564 266 0.068
organ morphogenesis GO:0009887 147 0.068
regulation of homeostatic process GO:0032844 121 0.066
rna interference GO:0016246 4 0.065
circulatory system development GO:0072359 262 0.064
positive regulation of endopeptidase activity GO:0010950 84 0.063
regulation of nucleocytoplasmic transport GO:0046822 98 0.061
posttranscriptional regulation of gene expression GO:0010608 213 0.061
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.060
cell growth GO:0016049 160 0.060
regulation of cell growth GO:0001558 135 0.059
regulation of protein transport GO:0051223 213 0.058
hematopoietic or lymphoid organ development GO:0048534 186 0.058
dna packaging GO:0006323 77 0.057
cell cycle phase transition GO:0044770 173 0.057
regulation of endopeptidase activity GO:0052548 170 0.057
covalent chromatin modification GO:0016569 254 0.056
histone exchange GO:0043486 3 0.054
negative regulation of phosphate metabolic process GO:0045936 267 0.050
nucleocytoplasmic transport GO:0006913 176 0.050
regulation of secretion GO:0051046 194 0.050
ribosome localization GO:0033750 4 0.049
negative regulation of multicellular organismal process GO:0051241 317 0.048
chemotaxis GO:0006935 157 0.046
regulation of cell cycle GO:0051726 393 0.046
positive regulation of hematopoietic progenitor cell differentiation GO:1901534 5 0.044
tube development GO:0035295 125 0.044
regulation of intracellular protein transport GO:0033157 123 0.044
activation of cysteine type endopeptidase activity GO:0097202 57 0.043
cardiovascular system development GO:0072358 262 0.041
multicellular organismal aging GO:0010259 3 0.041
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
regulation of erythrocyte differentiation GO:0045646 17 0.040
positive regulation of intracellular protein transport GO:0090316 76 0.040
response to bacterium GO:0009617 144 0.040
dna conformation change GO:0071103 113 0.039
negative regulation of cellular component organization GO:0051129 235 0.039
viral process GO:0016032 146 0.038
positive regulation of cell differentiation GO:0045597 211 0.037
cellular homeostasis GO:0019725 196 0.036
response to lipid GO:0033993 206 0.035
negative regulation of growth GO:0045926 97 0.035
regulation of protein export from nucleus GO:0046825 15 0.034
nuclear transport GO:0051169 179 0.034
interspecies interaction between organisms GO:0044419 156 0.034
response to abiotic stimulus GO:0009628 336 0.034
ribonucleoprotein complex export from nucleus GO:0071426 4 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.034
negative regulation of protein metabolic process GO:0051248 391 0.033
inflammatory response GO:0006954 79 0.033
viral life cycle GO:0019058 132 0.033
protein catabolic process GO:0030163 325 0.033
gene silencing GO:0016458 49 0.032
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.032
regulation of cell cycle phase transition GO:1901987 126 0.032
chromatin remodeling GO:0006338 55 0.032
lipid metabolic process GO:0006629 381 0.032
positive regulation of myeloid cell differentiation GO:0045639 39 0.032
growth GO:0040007 202 0.031
regulation of growth GO:0040008 165 0.031
regulation of cysteine type endopeptidase activity GO:2000116 127 0.031
dna replication dependent nucleosome organization GO:0034723 32 0.030
base excision repair GO:0006284 21 0.030
amine metabolic process GO:0009308 44 0.030
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.030
response to cytokine GO:0034097 232 0.030
secretion GO:0046903 254 0.029
base excision repair dna ligation GO:0006288 2 0.028
oogenesis GO:0048477 2 0.028
viral genome replication GO:0019079 50 0.027
defense response GO:0006952 315 0.027
positive regulation of cell cycle process GO:0090068 106 0.027
regulation of proteolysis GO:0030162 293 0.027
myeloid cell differentiation GO:0030099 117 0.027
forebrain generation of neurons GO:0021872 3 0.027
tube morphogenesis GO:0035239 95 0.027
determination of adult lifespan GO:0008340 2 0.026
epithelial cell proliferation GO:0050673 128 0.026
ribonucleoprotein complex biogenesis GO:0022613 116 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
negative regulation of cell death GO:0060548 345 0.026
nls bearing protein import into nucleus GO:0006607 2 0.026
positive chemotaxis GO:0050918 33 0.026
regulation of protein complex assembly GO:0043254 147 0.025
regulation of kinase activity GO:0043549 314 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
response to inorganic substance GO:0010035 127 0.025
mitotic cell cycle GO:0000278 326 0.024
nitrogen compound transport GO:0071705 191 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
zymogen activation GO:0031638 70 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.024
regulation of cellular response to stress GO:0080135 244 0.024
forebrain neuron differentiation GO:0021879 3 0.024
response to lipopolysaccharide GO:0032496 70 0.024
ribosomal subunit export from nucleus GO:0000054 4 0.023
regulation of response to dna damage stimulus GO:2001020 94 0.023
dna replication GO:0006260 116 0.023
regulation of protein kinase activity GO:0045859 289 0.023
cellular response to molecule of bacterial origin GO:0071219 62 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
ras protein signal transduction GO:0007265 73 0.022
cellular biogenic amine metabolic process GO:0006576 34 0.022
immune system development GO:0002520 195 0.022
response to drug GO:0042493 81 0.022
oxidation reduction process GO:0055114 396 0.021
negative regulation of cellular response to oxidative stress GO:1900408 18 0.021
semaphorin plexin signaling pathway GO:0071526 4 0.021
membrane organization GO:0061024 292 0.021
dna recombination GO:0006310 77 0.021
inflammatory response to antigenic stimulus GO:0002437 4 0.021
response to axon injury GO:0048678 1 0.021
regulation of binding GO:0051098 111 0.021
regulation of meiotic cell cycle GO:0051445 4 0.021
cell chemotaxis GO:0060326 112 0.021
negative regulation of protein modification process GO:0031400 200 0.020
histone deacetylation GO:0016575 32 0.020
regulation of transferase activity GO:0051338 355 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
cellular amine metabolic process GO:0044106 41 0.020
ribosomal large subunit export from nucleus GO:0000055 3 0.020
immune effector process GO:0002252 159 0.020
regulation of viral genome replication GO:0045069 48 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
g1 s transition of mitotic cell cycle GO:0000082 78 0.020
response to oxygen containing compound GO:1901700 369 0.019
wnt signaling pathway GO:0016055 156 0.019
sex determination GO:0007530 3 0.019
post embryonic development GO:0009791 2 0.019
cellular ketone metabolic process GO:0042180 80 0.019
erythrocyte homeostasis GO:0034101 31 0.019
regulation of gene expression epigenetic GO:0040029 73 0.019
sensory perception of pain GO:0019233 4 0.019
chromatin silencing GO:0006342 12 0.019
single organism membrane organization GO:0044802 268 0.019
negative regulation of cell cycle GO:0045786 193 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
negative regulation of protein complex assembly GO:0031333 43 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
regulation of cell maturation GO:1903429 3 0.018
mitotic cell cycle process GO:1903047 286 0.018
regulation of cellular component movement GO:0051270 334 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
taxis GO:0042330 157 0.018
somatic diversification of immune receptors GO:0002200 8 0.018
erythrocyte differentiation GO:0030218 28 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
protein maturation GO:0051604 233 0.017
positive regulation of protein export from nucleus GO:0046827 6 0.017
blastoderm segmentation GO:0007350 2 0.017
digestive system development GO:0055123 75 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
ear development GO:0043583 14 0.017
negative regulation of phosphatase activity GO:0010923 61 0.017
neuron apoptotic process GO:0051402 39 0.017
regulation of secretion by cell GO:1903530 177 0.017
regulation of cell motility GO:2000145 299 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
heart morphogenesis GO:0003007 48 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
oocyte development GO:0048599 1 0.016
histone methylation GO:0016571 60 0.016
protein targeting GO:0006605 187 0.016
negative regulation of gene expression epigenetic GO:0045814 19 0.015
negative regulation of dna templated transcription initiation GO:2000143 3 0.015
positive regulation of multi organism process GO:0043902 56 0.015
positive regulation of binding GO:0051099 45 0.015
ventricular system development GO:0021591 1 0.015
cell cycle g1 s phase transition GO:0044843 80 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
response to decreased oxygen levels GO:0036293 96 0.015
positive regulation of viral process GO:0048524 37 0.015
rna processing GO:0006396 255 0.015
response to uv GO:0009411 73 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
cell morphogenesis GO:0000902 296 0.015
positive regulation of dna metabolic process GO:0051054 73 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
glycerolipid biosynthetic process GO:0045017 51 0.014
response to other organism GO:0051707 261 0.014
response to oxidative stress GO:0006979 121 0.014
regulation of dna replication GO:0006275 68 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
locomotory behavior GO:0007626 1 0.014
protein export from nucleus GO:0006611 29 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
regulation of multi organism process GO:0043900 157 0.014
positive regulation of cell cycle GO:0045787 140 0.014
mrna metabolic process GO:0016071 175 0.014
dephosphorylation GO:0016311 209 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
single organism cellular localization GO:1902580 332 0.014
response to hypoxia GO:0001666 96 0.013
positive regulation of homeostatic process GO:0032846 47 0.013
neuromuscular junction development GO:0007528 3 0.013
dopaminergic neuron differentiation GO:0071542 1 0.013
neurogenesis GO:0022008 169 0.013
regulation of cell migration GO:0030334 289 0.013
rna splicing GO:0008380 131 0.013
forebrain neuron development GO:0021884 2 0.013
oocyte differentiation GO:0009994 2 0.013
cell development GO:0048468 328 0.013
histone modification GO:0016570 251 0.013
lipid biosynthetic process GO:0008610 177 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
regulation of oocyte development GO:0060281 1 0.013
pituitary gland development GO:0021983 2 0.013
embryonic morphogenesis GO:0048598 85 0.013
ribonucleoprotein complex subunit organization GO:0071826 81 0.013
cerebral cortex radially oriented cell migration GO:0021799 1 0.013
glial cell migration GO:0008347 4 0.013
regulation of leukocyte chemotaxis GO:0002688 46 0.013
hematopoietic progenitor cell differentiation GO:0002244 38 0.013
neural tube formation GO:0001841 3 0.012
pattern recognition receptor signaling pathway GO:0002221 48 0.012
sensory organ development GO:0007423 52 0.012
positive regulation of defense response GO:0031349 87 0.012
response to oxygen levels GO:0070482 100 0.012
anterior posterior axis specification GO:0009948 2 0.012
palate development GO:0060021 13 0.012
negative regulation of dephosphorylation GO:0035305 63 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
positive regulation of secretion GO:0051047 116 0.012
response to wounding GO:0009611 168 0.012
protein methylation GO:0006479 74 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
phospholipid metabolic process GO:0006644 99 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of defense response GO:0031347 154 0.012
nucleic acid transport GO:0050657 39 0.012
g2 m transition of mitotic cell cycle GO:0000086 41 0.012
meiosis i GO:0007127 4 0.012
cellular response to lipid GO:0071396 127 0.012
response to biotic stimulus GO:0009607 276 0.012
rna transport GO:0050658 39 0.012
response to light stimulus GO:0009416 87 0.012
digestive tract development GO:0048565 75 0.012
organelle localization GO:0051640 84 0.012
ossification GO:0001503 121 0.012
positive regulation of immune response GO:0050778 159 0.012
negative regulation of oxidative stress induced cell death GO:1903202 17 0.012
regulation of feeding behavior GO:0060259 3 0.011
dna replication independent nucleosome assembly GO:0006336 27 0.011
cell type specific apoptotic process GO:0097285 125 0.011
microtubule based process GO:0007017 210 0.011
cellular response to oxidative stress GO:0034599 85 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
cerebral cortex cell migration GO:0021795 3 0.011
rna 3 end processing GO:0031123 35 0.011
protein localization to membrane GO:0072657 160 0.011
camp metabolic process GO:0046058 61 0.011
response to acid chemical GO:0001101 66 0.011
maintenance of location GO:0051235 112 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of dna binding GO:0051101 37 0.011
regulation of locomotion GO:0040012 329 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
establishment of tissue polarity GO:0007164 3 0.011
regulation of endothelial cell proliferation GO:0001936 56 0.011
negative regulation of transport GO:0051051 176 0.011
secretion by cell GO:0032940 226 0.011
negative regulation of cytoskeleton organization GO:0051494 45 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
chemical homeostasis GO:0048878 306 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
mrna processing GO:0006397 133 0.010
organelle fission GO:0048285 149 0.010
neuron death GO:0070997 65 0.010
cofactor metabolic process GO:0051186 87 0.010
purine nucleoside triphosphate metabolic process GO:0009144 412 0.010
posttranscriptional gene silencing GO:0016441 25 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
tissue regeneration GO:0042246 3 0.010

PTMA disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.083
cancer DOID:162 167 0.058
disease of cellular proliferation DOID:14566 174 0.058
organ system cancer DOID:0050686 164 0.058
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
immune system disease DOID:2914 155 0.011