|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
1.000
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
1.000
|
Mouse Rat |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
1.000
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
1.000
|
Mouse Rat |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
1.000
|
Mouse Rat |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
1.000
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
1.000
|
Mouse Rat |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
1.000
|
Mouse Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
1.000
|
Mouse Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
1.000
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
1.000
|
Mouse Rat |
|
|
response to hormone
|
GO:0009725 |
175 |
1.000
|
Mouse Rat |
|
|
response to interleukin 15
|
GO:0070672 |
6 |
1.000
|
Human |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
1.000
|
Mouse Rat |
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
1.000
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
1.000
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
1.000
|
Mouse Rat |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
Mouse Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
1.000
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
1.000
|
Human |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
1.000
|
Mouse Rat |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
1.000
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
1.000
|
Human Yeast Mouse |
|
|
cellular response to interleukin 15
|
GO:0071350 |
6 |
1.000
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
1.000
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
1.000
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
4 |
1.000
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
1.000
|
Human Yeast Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
1.000
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
1.000
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
1.000
|
Human |
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
1.000
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.999
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.999
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.999
|
Human Yeast Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.999
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.999
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.999
|
Mouse Rat |
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.999
|
Human |
|
|
positive regulation of cellular response to insulin stimulus
|
GO:1900078 |
6 |
0.999
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
13 |
0.999
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
23 |
0.999
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.999
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.999
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.999
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.999
|
Human Yeast Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.999
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.999
|
Human Yeast Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.998
|
Yeast |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.998
|
Human Yeast Mouse |
|
|
taurine metabolic process
|
GO:0019530 |
1 |
0.998
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.998
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.998
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.998
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.998
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.998
|
Mouse Rat |
|
|
long term memory
|
GO:0007616 |
2 |
0.998
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.998
|
Human |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.997
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.997
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.997
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.997
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.997
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.997
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.997
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.997
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.997
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.997
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.996
|
Mouse Rat |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.996
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.996
|
Yeast Mouse |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.996
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.996
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.996
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.996
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.995
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.995
|
Human |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.994
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.994
|
Rat |
|
|
regeneration
|
GO:0031099 |
4 |
0.994
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.994
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.994
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.994
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.994
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.993
|
|
|
|
cellular lactam metabolic process
|
GO:0072338 |
1 |
0.993
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.993
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.993
|
|
|
|
positive regulation of glucose import in response to insulin stimulus
|
GO:2001275 |
3 |
0.992
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.991
|
Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.991
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.991
|
|
|
|
positive regulation of natural killer cell differentiation
|
GO:0032825 |
2 |
0.990
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.990
|
Mouse Rat |
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
4 |
0.990
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.989
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.989
|
|
|
|
activation of protein kinase b activity
|
GO:0032148 |
14 |
0.989
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.989
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.989
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.989
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.988
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.988
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.988
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
8 |
0.987
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.987
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.987
|
|
|
|
response to interleukin 4
|
GO:0070670 |
7 |
0.987
|
Human |
|
|
memory
|
GO:0007613 |
3 |
0.986
|
|
|
|
growth
|
GO:0040007 |
202 |
0.986
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.986
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.986
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.986
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.986
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.986
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.986
|
Yeast |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.986
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.985
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.985
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.985
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.984
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.984
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.983
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.982
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.982
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.982
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.982
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.981
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.981
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.981
|
Yeast Mouse |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.981
|
Human |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.979
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.979
|
Yeast |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.979
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.977
|
|
|
|
glucose transport
|
GO:0015758 |
30 |
0.977
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.977
|
Human |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.976
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.976
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.976
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.975
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.975
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.975
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.975
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.973
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.972
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.971
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.970
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
25 |
0.970
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.969
|
Yeast Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.969
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.969
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.967
|
Yeast Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.966
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.966
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.966
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.964
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
9 |
0.963
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.963
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.963
|
|
|
|
response to interleukin 13
|
GO:0035962 |
4 |
0.962
|
|
|
|
oxaloacetate metabolic process
|
GO:0006107 |
1 |
0.961
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.961
|
|
|
|
hexose transport
|
GO:0008645 |
30 |
0.961
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.960
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.958
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.958
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.957
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
7 |
0.955
|
Human |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.954
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.953
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.952
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.952
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.951
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.950
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.949
|
Yeast |
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.948
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.948
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.948
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.944
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.941
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.939
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.939
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.939
|
Yeast Mouse |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.939
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.938
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.935
|
Yeast Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.934
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.931
|
Human Yeast Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.931
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.929
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.928
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.928
|
Human |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.927
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.926
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.925
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.924
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.923
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.923
|
Yeast Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.922
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.921
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.921
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.921
|
|
|
|
system process
|
GO:0003008 |
349 |
0.920
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.920
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.919
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.919
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.919
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
1 |
0.918
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.916
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.916
|
Human |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.913
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.911
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.911
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.910
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.907
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.902
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.901
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.900
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.900
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.899
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.898
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.898
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.893
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.891
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.890
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.888
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.886
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.881
|
Human |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.881
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.881
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.878
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.877
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.875
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.875
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.875
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
3 |
0.874
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.874
|
|
|
|
glucose import
|
GO:0046323 |
24 |
0.873
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.870
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.870
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.867
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.867
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.867
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.866
|
Yeast Mouse |
|
|
renal system development
|
GO:0072001 |
63 |
0.866
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.865
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.863
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.863
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.860
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.858
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.857
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.856
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.855
|
Yeast |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.855
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.855
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.854
|
Yeast Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.851
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.849
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.848
|
Human |
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.848
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.848
|
Yeast Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.847
|
Mouse |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.845
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.844
|
|
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.842
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.842
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.840
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.839
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.834
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.834
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.834
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.832
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.831
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.826
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.825
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.825
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.822
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
2 |
0.822
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.821
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.820
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.820
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.818
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.818
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.818
|
Human |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.815
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.815
|
Human Yeast Mouse |
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.813
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.813
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.813
|
|
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
6 |
0.813
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.812
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.811
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.809
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.808
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.808
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.808
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.808
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.806
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.805
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.801
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.797
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.796
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.795
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.792
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
4 |
0.790
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.781
|
|
|
|
protein autoprocessing
|
GO:0016540 |
4 |
0.780
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.776
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.775
|
|
|
|
regulation of glucan biosynthetic process
|
GO:0010962 |
14 |
0.775
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.774
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.771
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.764
|
|
|
|
glucose import in response to insulin stimulus
|
GO:0044381 |
4 |
0.763
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.760
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.756
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.755
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.750
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.750
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
15 |
0.749
|
|
|
|
regulation of striated muscle cell apoptotic process
|
GO:0010662 |
3 |
0.748
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.746
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.745
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.742
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.736
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.733
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.731
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.730
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.721
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.718
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.715
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.715
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.712
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.708
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.707
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.702
|
|
|
|
regulation of glycogen biosynthetic process
|
GO:0005979 |
14 |
0.694
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.692
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.691
|
Yeast |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.691
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.689
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.688
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.688
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.687
|
|
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
20 |
0.685
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.679
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.679
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
8 |
0.677
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.674
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.672
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.670
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.667
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.662
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.662
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.659
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.659
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.654
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.654
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.653
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.653
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.649
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.646
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.645
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.644
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.643
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.643
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.641
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.640
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.640
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.639
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.636
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.636
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.634
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.631
|
|
|
|
positive regulation of glucose import
|
GO:0046326 |
16 |
0.631
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.629
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.628
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.628
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.627
|
|
|
|
cellular response to interleukin 12
|
GO:0071349 |
3 |
0.622
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.621
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.620
|
Yeast |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.617
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.616
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.610
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.610
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.610
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.610
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.610
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.604
|
Human |
|
|
renal tubule development
|
GO:0061326 |
19 |
0.601
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.597
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.595
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.592
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.592
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.592
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.592
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.591
|
|
|
|
activation of jak2 kinase activity
|
GO:0042977 |
5 |
0.588
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.587
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.583
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.581
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.580
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.580
|
|
|
|
response to interferon beta
|
GO:0035456 |
11 |
0.576
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.575
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.574
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.574
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.571
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.570
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.569
|
Human |
|
|
lipid transport
|
GO:0006869 |
90 |
0.569
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.567
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.567
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.565
|
|
|
|
positive regulation of coagulation
|
GO:0050820 |
11 |
0.565
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.563
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.562
|
Human |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.561
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.561
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.558
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.558
|
|
|
|
regulation of glucose import in response to insulin stimulus
|
GO:2001273 |
4 |
0.557
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.557
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.554
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.553
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.553
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.551
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
16 |
0.550
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.547
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.539
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.538
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.536
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.528
|
|
|
|
creatine metabolic process
|
GO:0006600 |
2 |
0.528
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.526
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.522
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.521
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.518
|
|
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
15 |
0.513
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.511
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.509
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.506
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.503
|
Yeast |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.502
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.500
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.494
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.491
|
|
|
|
female sex differentiation
|
GO:0046660 |
12 |
0.491
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.490
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.488
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.485
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.485
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.483
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.482
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.480
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.478
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.477
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.476
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.476
|
Yeast |
|
|
gastrulation
|
GO:0007369 |
51 |
0.475
|
|
|
|
cortisol secretion
|
GO:0043400 |
4 |
0.474
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.472
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.470
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.468
|
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.467
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.464
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.464
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.464
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
10 |
0.460
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.458
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.457
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.456
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.454
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.454
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.451
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.449
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.445
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.441
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.440
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.438
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.435
|
Human |
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.434
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.434
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.432
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.432
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.431
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.426
|
|
|
|
negative regulation of hydrogen peroxide mediated programmed cell death
|
GO:1901299 |
3 |
0.426
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.425
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.423
|
|
