Homo sapiens

144 known processes

PTPN2

protein tyrosine phosphatase, non-receptor type 2

(Aliases: PTN2,TCELLPTP,TC-PTP,TCPTP,PTPT)

PTPN2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lactam metabolic process GO:0072338 1 0.540
growth GO:0040007 202 0.436
Yeast
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.424
enzyme linked receptor protein signaling pathway GO:0007167 303 0.380
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.357
regulation of growth GO:0040008 165 0.279
cellular response to endogenous stimulus GO:0071495 336 0.266
Mouse
female gamete generation GO:0007292 2 0.258
branched chain amino acid metabolic process GO:0009081 4 0.238
regulation of cellular ketone metabolic process GO:0010565 50 0.232
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.210
cellular amine metabolic process GO:0044106 41 0.208
creatinine metabolic process GO:0046449 1 0.207
vesicle mediated transport GO:0016192 371 0.170
Human
regulation of kinase activity GO:0043549 314 0.167
regulation of protein serine threonine kinase activity GO:0071900 179 0.160
regulation of transferase activity GO:0051338 355 0.155
response to interleukin 1 GO:0070555 47 0.155
negative regulation of protein metabolic process GO:0051248 391 0.153
positive regulation of cellular amine metabolic process GO:0033240 7 0.153
cell growth GO:0016049 160 0.152
Yeast
positive regulation of protein phosphorylation GO:0001934 313 0.150
tricarboxylic acid metabolic process GO:0072350 4 0.148
positive regulation of protein kinase activity GO:0045860 190 0.144
cellular amino acid metabolic process GO:0006520 116 0.142
mapk cascade GO:0000165 288 0.136
Mouse
negative regulation of protein phosphorylation GO:0001933 140 0.136
regulation of cellular component biogenesis GO:0044087 281 0.134
positive regulation of phosphorylation GO:0042327 394 0.132
amine metabolic process GO:0009308 44 0.127
negative regulation of cell death GO:0060548 345 0.124
oogenesis GO:0048477 2 0.123
positive regulation of cellular component organization GO:0051130 376 0.121
negative regulation of growth GO:0045926 97 0.117
endocytosis GO:0006897 159 0.115
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.115
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.114
regulation of protein kinase activity GO:0045859 289 0.111
signal transduction by phosphorylation GO:0023014 297 0.108
Mouse
regulation of interleukin 6 mediated signaling pathway GO:0070103 3 0.105
pericardium development GO:0060039 2 0.101
protein dephosphorylation GO:0006470 81 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.100
regulation of immune response GO:0050776 201 0.100
negative regulation of developmental process GO:0051093 247 0.099
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.098
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.098
fatty acid metabolic process GO:0006631 115 0.097
response to oxygen containing compound GO:1901700 369 0.096
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.095
epithelium development GO:0060429 227 0.094
regulation of mapk cascade GO:0043408 262 0.093
Mouse
positive regulation of mapk cascade GO:0043410 190 0.093
cellular ketone metabolic process GO:0042180 80 0.092
Mouse
positive regulation of map kinase activity GO:0043406 80 0.091
oxaloacetate metabolic process GO:0006107 1 0.089
cell activation GO:0001775 213 0.088
Mouse
immune response GO:0006955 307 0.088
cellular macromolecular complex assembly GO:0034622 324 0.086
nervous system development GO:0007399 293 0.085
oocyte differentiation GO:0009994 2 0.084
cell projection organization GO:0030030 252 0.083
post embryonic development GO:0009791 2 0.080
regulation of map kinase activity GO:0043405 108 0.080
regulation of protein localization GO:0032880 296 0.077
succinate metabolic process GO:0006105 1 0.076
regulation of establishment of protein localization GO:0070201 242 0.076
regulation of wnt signaling pathway GO:0030111 123 0.074
cellular response to oxygen containing compound GO:1901701 276 0.074
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.074
negative regulation of cell proliferation GO:0008285 228 0.074
cell development GO:0048468 328 0.072
positive regulation of developmental process GO:0051094 314 0.071
positive regulation of kinase activity GO:0033674 204 0.071
endomembrane system organization GO:0010256 196 0.067
endochondral bone morphogenesis GO:0060350 3 0.067
sulfur compound metabolic process GO:0006790 101 0.067
cell morphogenesis GO:0000902 296 0.063
negative regulation of programmed cell death GO:0043069 321 0.063
multicellular organismal aging GO:0010259 3 0.063
oocyte development GO:0048599 1 0.062
cellular response to hormone stimulus GO:0032870 125 0.060
Mouse
negative regulation of protein modification process GO:0031400 200 0.060
negative regulation of intracellular signal transduction GO:1902532 183 0.060
negative regulation of catalytic activity GO:0043086 335 0.060
regulation of cell differentiation GO:0045595 393 0.059
Mouse
regulation of cellular component movement GO:0051270 334 0.059
neuromuscular junction development GO:0007528 3 0.057
cellular amide metabolic process GO:0043603 69 0.057
cellular response to growth factor stimulus GO:0071363 197 0.057
negative regulation of kinase activity GO:0033673 106 0.056
cellular lipid metabolic process GO:0044255 303 0.056
response to cytokine GO:0034097 232 0.055
multicellular organismal metabolic process GO:0044236 34 0.053
positive regulation of cell death GO:0010942 263 0.053
peptidyl tyrosine modification GO:0018212 170 0.053
citrate metabolic process GO:0006101 2 0.053
lipid metabolic process GO:0006629 381 0.052
neuron death GO:0070997 65 0.052
post embryonic organ development GO:0048569 1 0.052
negative regulation of phosphorylation GO:0042326 174 0.052
response to cycloheximide GO:0046898 1 0.051
dephosphorylation GO:0016311 209 0.051
wnt signaling pathway GO:0016055 156 0.051
membrane organization GO:0061024 292 0.051
vasodilation GO:0042311 4 0.051
memory GO:0007613 3 0.050
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
long term memory GO:0007616 2 0.049
activation of protein kinase activity GO:0032147 90 0.049
cellular component morphogenesis GO:0032989 314 0.049
negative regulation of phosphorus metabolic process GO:0010563 267 0.048
regulation of protein processing GO:0070613 150 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.047
cytoplasmic transport GO:0016482 379 0.046
regulation of proteolysis GO:0030162 293 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.045
negative regulation of apoptotic process GO:0043066 316 0.045
lymphocyte activation GO:0046649 133 0.045
Mouse
response to insulin GO:0032868 45 0.044
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.044
renal system development GO:0072001 63 0.043
cellular response to nitrogen compound GO:1901699 144 0.043
Mouse
regulation of locomotion GO:0040012 329 0.043
Mouse
response to organonitrogen compound GO:0010243 156 0.042
Mouse
negative regulation of type i interferon mediated signaling pathway GO:0060339 4 0.042
reproductive process GO:0022414 106 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.041
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.041
cell projection morphogenesis GO:0048858 129 0.039
peptidyl tyrosine dephosphorylation GO:0035335 36 0.039
positive regulation of programmed cell death GO:0043068 249 0.039
cell part morphogenesis GO:0032990 137 0.039
determination of adult lifespan GO:0008340 2 0.038
single organismal cell cell adhesion GO:0016337 148 0.038
establishment of protein localization to membrane GO:0090150 121 0.037
positive regulation of catabolic process GO:0009896 310 0.037
protein catabolic process GO:0030163 325 0.037
cellular protein complex assembly GO:0043623 188 0.036
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.036
ion transmembrane transport GO:0034220 338 0.036
receptor mediated endocytosis GO:0006898 84 0.035
monocarboxylic acid metabolic process GO:0032787 185 0.035
plasma membrane organization GO:0007009 115 0.035
hormone mediated signaling pathway GO:0009755 22 0.035
Mouse
actin cytoskeleton organization GO:0030036 207 0.034
Human
immune effector process GO:0002252 159 0.033
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.033
response to hormone GO:0009725 175 0.033
Mouse
alpha amino acid metabolic process GO:1901605 72 0.033
ribonucleoside catabolic process GO:0042454 406 0.032
nephron development GO:0072006 30 0.032
blood circulation GO:0008015 113 0.032
chemotaxis GO:0006935 157 0.032
Mouse
rna processing GO:0006396 255 0.031
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 2 0.031
regulation of binding GO:0051098 111 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
regulation of cell migration GO:0030334 289 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.030
intracellular protein transport GO:0006886 270 0.030
regulation of intracellular protein transport GO:0033157 123 0.030
regulation of intracellular transport GO:0032386 195 0.030
response to growth hormone GO:0060416 11 0.029
purine nucleoside catabolic process GO:0006152 398 0.029
positive regulation of immune system process GO:0002684 283 0.029
Mouse
cellular response to organonitrogen compound GO:0071417 124 0.029
Mouse
oxidation reduction process GO:0055114 396 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
protein localization to membrane GO:0072657 160 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.028
response to peptide hormone GO:0043434 61 0.028
Mouse
nuclear transport GO:0051169 179 0.028
regulation of cell growth GO:0001558 135 0.028
generation of neurons GO:0048699 152 0.027
response to organic cyclic compound GO:0014070 204 0.027
activation of mapk activity GO:0000187 45 0.027
cell division GO:0051301 168 0.027
inorganic cation transmembrane transport GO:0098662 194 0.027
circulatory system process GO:0003013 113 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
leukocyte activation GO:0045321 164 0.026
Mouse
cytokine mediated signaling pathway GO:0019221 109 0.026
protein maturation GO:0051604 233 0.026
negative regulation of cell differentiation GO:0045596 171 0.026
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.026
positive regulation of cell differentiation GO:0045597 211 0.026
regulation of protein maturation GO:1903317 150 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
regulation of cell cycle process GO:0010564 266 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
taxis GO:0042330 157 0.025
Mouse
response to alkaloid GO:0043279 20 0.024
single organism cell adhesion GO:0098602 179 0.024
interleukin 2 mediated signaling pathway GO:0038110 3 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
t cell activation GO:0042110 99 0.024
Mouse
response to peptide GO:1901652 65 0.024
Mouse
skin development GO:0043588 76 0.024
negative regulation of cell cycle GO:0045786 193 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
response to abiotic stimulus GO:0009628 336 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.023
mitotic cell cycle process GO:1903047 286 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
nucleotide catabolic process GO:0009166 408 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
activation of jak2 kinase activity GO:0042977 5 0.023
regulation of nucleocytoplasmic transport GO:0046822 98 0.023
behavioral response to ethanol GO:0048149 2 0.022
sodium ion transport GO:0006814 61 0.022
defense response GO:0006952 315 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
cell matrix adhesion GO:0007160 85 0.022
regulation of anatomical structure size GO:0090066 101 0.022
nitrogen compound transport GO:0071705 191 0.022
neuron projection development GO:0031175 106 0.022
segmentation GO:0035282 4 0.022
regulation of lymphocyte activation GO:0051249 103 0.022
Mouse
mitotic cell cycle GO:0000278 326 0.022
regulation of cellular response to growth factor stimulus GO:0090287 76 0.022
hemopoiesis GO:0030097 180 0.022
Mouse
purine containing compound catabolic process GO:0072523 411 0.022
regulation of neuron death GO:1901214 56 0.022
nucleoside catabolic process GO:0009164 408 0.022
protein localization to plasma membrane GO:0072659 93 0.021
regeneration GO:0031099 4 0.021
embryo development GO:0009790 123 0.021
spermatid development GO:0007286 4 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
cellular response to peptide GO:1901653 59 0.021
Mouse
response to tumor necrosis factor GO:0034612 76 0.021
Mouse
response to extracellular stimulus GO:0009991 85 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.021
regulation of ion transmembrane transport GO:0034765 132 0.021
negative regulation of cell growth GO:0030308 83 0.021
activation of janus kinase activity GO:0042976 7 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
Mouse
developmental growth GO:0048589 48 0.021
locomotory behavior GO:0007626 1 0.021
mrna metabolic process GO:0016071 175 0.020
negative regulation of protein maturation GO:1903318 142 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
skeletal system development GO:0001501 79 0.020
organophosphate catabolic process GO:0046434 430 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
cellular protein catabolic process GO:0044257 261 0.020
response to transforming growth factor beta GO:0071559 94 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
regulation of membrane potential GO:0042391 95 0.020
actin filament based process GO:0030029 224 0.020
Human
receptor internalization GO:0031623 43 0.020
dicarboxylic acid metabolic process GO:0043648 29 0.019
negative regulation of cell motility GO:2000146 104 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
cell chemotaxis GO:0060326 112 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
regulation of cell cycle GO:0051726 393 0.019
vascular process in circulatory system GO:0003018 29 0.019
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.019
regulation of protein transport GO:0051223 213 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.018
Mouse
positive regulation of growth GO:0045927 58 0.018
cell adhesion GO:0007155 325 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
negative regulation of transport GO:0051051 176 0.018
regulation of action potential GO:0098900 2 0.018
neurogenesis GO:0022008 169 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
negative regulation of cellular catabolic process GO:0031330 83 0.018
single organism membrane organization GO:0044802 268 0.018
single organism cellular localization GO:1902580 332 0.018
regulation of transporter activity GO:0032409 82 0.018
negative regulation of mitotic cell cycle GO:0045930 102 0.018
response to alcohol GO:0097305 64 0.018
mrna processing GO:0006397 133 0.018
negative regulation of protein processing GO:0010955 142 0.018
regulation of multi organism process GO:0043900 157 0.017
activation of immune response GO:0002253 114 0.017
Mouse
response to growth factor GO:0070848 205 0.017
anterior posterior axis specification GO:0009948 2 0.017
cell substrate adhesion GO:0031589 132 0.017
response to estrogen GO:0043627 47 0.017
negative regulation of proteolysis GO:0045861 132 0.017
multi organism reproductive process GO:0044703 54 0.017
myeloid leukocyte migration GO:0097529 62 0.017
leukocyte chemotaxis GO:0030595 76 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
regulation of cellular response to stress GO:0080135 244 0.017
regulation of transmembrane transporter activity GO:0022898 74 0.017
atp metabolic process GO:0046034 176 0.017
biological adhesion GO:0022610 331 0.017
chromatin organization GO:0006325 351 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.017
2 oxoglutarate metabolic process GO:0006103 4 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
reproduction GO:0000003 63 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
response to axon injury GO:0048678 1 0.017
glycoprotein metabolic process GO:0009100 110 0.016
secretion GO:0046903 254 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
carbohydrate metabolic process GO:0005975 207 0.016
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
growth hormone receptor signaling pathway GO:0060396 10 0.016
protein processing GO:0016485 226 0.016
skeletal system morphogenesis GO:0048705 24 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
regulation of lymphocyte proliferation GO:0050670 64 0.016
gland development GO:0048732 48 0.016
single organism reproductive process GO:0044702 98 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
rna interference GO:0016246 4 0.016
response to nutrient levels GO:0031667 81 0.016
negative regulation of transferase activity GO:0051348 124 0.015
regulation of dna metabolic process GO:0051052 153 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of secretion GO:0051046 194 0.015
innate immune response GO:0045087 178 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
organelle assembly GO:0070925 176 0.015
response to steroid hormone GO:0048545 80 0.015
negative regulation of locomotion GO:0040013 118 0.015
Mouse
establishment of protein localization to plasma membrane GO:0090002 68 0.015
negative regulation of binding GO:0051100 57 0.015
response to estradiol GO:0032355 23 0.015
multi organism cellular process GO:0044764 156 0.015
ossification GO:0001503 121 0.015
cellular response to unfolded protein GO:0034620 16 0.015
Human
nuclear export GO:0051168 69 0.015
positive regulation of jak stat cascade GO:0046427 35 0.015
protein autophosphorylation GO:0046777 123 0.015
cell junction assembly GO:0034329 67 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of innate immune response GO:0045088 97 0.015
chromatin modification GO:0016568 298 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
immune response regulating signaling pathway GO:0002764 97 0.015
Mouse
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.015
Human Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
protein localization to organelle GO:0033365 280 0.015
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.014
behavior GO:0007610 112 0.014
Mouse
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.014
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
translation GO:0006412 132 0.014
cellular response to peptide hormone stimulus GO:0071375 56 0.014
Mouse
regulation of blood vessel size GO:0050880 18 0.014
positive regulation of secretion by cell GO:1903532 108 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
regulation of response to external stimulus GO:0032101 222 0.014
Mouse
regulation of cell motility GO:2000145 299 0.014
leukocyte proliferation GO:0070661 74 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
response to oxidative stress GO:0006979 121 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
negative regulation of cellular component movement GO:0051271 106 0.014
protein oligomerization GO:0051259 173 0.014
cellular extravasation GO:0045123 21 0.014
positive regulation of transport GO:0051050 336 0.014
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.014
lipid localization GO:0010876 106 0.014
Mouse
response to lipid GO:0033993 206 0.014
response to radiation GO:0009314 151 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
dna replication GO:0006260 116 0.014
protein secretion GO:0009306 98 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of protein catabolic process GO:0042176 155 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
cartilage development GO:0051216 31 0.013
g protein coupled receptor signaling pathway GO:0007186 207 0.013
blood vessel development GO:0001568 172 0.013
cardiovascular system development GO:0072358 262 0.013
somatic stem cell division GO:0048103 1 0.013
response to interleukin 15 GO:0070672 6 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
asymmetric stem cell division GO:0098722 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of cell division GO:0051302 116 0.013
stem cell division GO:0017145 2 0.013
membrane depolarization during action potential GO:0086010 10 0.013
histone modification GO:0016570 251 0.013
positive regulation of organelle organization GO:0010638 195 0.013
response to other organism GO:0051707 261 0.013
cell type specific apoptotic process GO:0097285 125 0.013
negative regulation of immune response GO:0050777 40 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
Mouse
tripartite regional subdivision GO:0007351 2 0.013
dna conformation change GO:0071103 113 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of protein binding GO:0032091 35 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
regulation of endocytosis GO:0030100 72 0.012
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
regulation of dephosphorylation GO:0035303 96 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
response to fungus GO:0009620 4 0.012
protein targeting GO:0006605 187 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
cytokine production GO:0001816 247 0.012
blastoderm segmentation GO:0007350 2 0.012
organ morphogenesis GO:0009887 147 0.012
ncrna processing GO:0034470 83 0.012
developmental process involved in reproduction GO:0003006 66 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of secretion by cell GO:1903530 177 0.012
associative learning GO:0008306 1 0.012
cell projection assembly GO:0030031 126 0.012
creatine metabolic process GO:0006600 2 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
regulation of protein binding GO:0043393 66 0.012
response to decreased oxygen levels GO:0036293 96 0.012
protein dna complex subunit organization GO:0071824 80 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
microtubule based process GO:0007017 210 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
cellular response to growth hormone stimulus GO:0071378 10 0.012
neuronal stem cell division GO:0036445 1 0.012
positive regulation of protein transport GO:0051222 135 0.012
rna splicing GO:0008380 131 0.011
cellular response to topologically incorrect protein GO:0035967 19 0.011
Human
response to glucocorticoid GO:0051384 13 0.011
maintenance of location GO:0051235 112 0.011
Mouse
regulation of protein complex assembly GO:0043254 147 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
osteoblast differentiation GO:0001649 92 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
organelle fission GO:0048285 149 0.011
response to bacterium GO:0009617 144 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
phospholipid metabolic process GO:0006644 99 0.011
meiosis i GO:0007127 4 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
positive regulation of proteolysis GO:0045862 142 0.011
antigen receptor mediated signaling pathway GO:0050851 38 0.011
Mouse
regulation of protein localization to plasma membrane GO:1903076 40 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
regulation of peptidase activity GO:0052547 180 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
leukocyte cell cell adhesion GO:0007159 37 0.011
nuclear division GO:0000280 128 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
muscle structure development GO:0061061 98 0.010
atp catabolic process GO:0006200 157 0.010
insulin like growth factor receptor signaling pathway GO:0048009 13 0.010
response to nitrogen compound GO:1901698 184 0.010
Mouse
interspecies interaction between organisms GO:0044419 156 0.010
response to wounding GO:0009611 168 0.010
Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
regulation of immune effector process GO:0002697 91 0.010
cell cell signaling GO:0007267 155 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
cell cycle phase transition GO:0044770 173 0.010
negative regulation of organelle organization GO:0010639 126 0.010
regulation of developmental growth GO:0048638 30 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010

PTPN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.410
Human
inherited metabolic disorder DOID:655 242 0.274
diabetes mellitus DOID:9351 31 0.046
Human
type 2 diabetes mellitus DOID:9352 28 0.046
Human
carbohydrate metabolism disease DOID:0050013 32 0.046
Human
glucose metabolism disease DOID:4194 32 0.046
Human
acquired metabolic disease DOID:0060158 58 0.046
Human
familial hyperlipidemia DOID:1168 9 0.043
lipid metabolism disorder DOID:3146 26 0.043
familial hypercholesterolemia DOID:13810 7 0.025
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
central nervous system disease DOID:331 186 0.013