Homo sapiens

116 known processes

PTPN23

protein tyrosine phosphatase, non-receptor type 23

(Aliases: HD-PTP,PTP-TD14,DKFZp564F0923,HDPTP,KIAA1471)

PTPN23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
viral budding GO:0046755 9 1.000
multi organism membrane organization GO:0044803 12 0.998
virion assembly GO:0019068 14 0.992
membrane budding GO:0006900 28 0.986
Yeast
multi organism membrane budding GO:1902592 9 0.985
viral budding via host escrt complex GO:0039702 7 0.977
multi organism organelle organization GO:1902590 9 0.969
negative regulation of cytokinesis GO:0032466 3 0.933
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.897
Fly
viral life cycle GO:0019058 132 0.824
viral process GO:0016032 146 0.765
cellular amine metabolic process GO:0044106 41 0.739
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.708
abscission GO:0009838 5 0.659
multi organism cellular process GO:0044764 156 0.617
regulation of cellular response to growth factor stimulus GO:0090287 76 0.574
posttranslational protein targeting to membrane GO:0006620 5 0.534
receptor internalization GO:0031623 43 0.499
autophagy GO:0006914 88 0.494
intracellular protein transport GO:0006886 270 0.483
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 303 0.459
Fly
positive regulation of cellular component biogenesis GO:0044089 158 0.442
vacuole organization GO:0007033 44 0.438
negative regulation of cell cycle process GO:0010948 121 0.437
positive regulation of vasodilation GO:0045909 4 0.436
membrane organization GO:0061024 292 0.428
Yeast
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.423
ras protein signal transduction GO:0007265 73 0.418
regulation of cellular ketone metabolic process GO:0010565 50 0.416
small gtpase mediated signal transduction GO:0007264 78 0.411
positive regulation of endothelial cell migration GO:0010595 39 0.411
cellular response to growth factor stimulus GO:0071363 197 0.394
regulation of mitotic cell cycle GO:0007346 189 0.383
actin filament polymerization GO:0030041 45 0.380
protein homooligomerization GO:0051260 100 0.375
monovalent inorganic cation transport GO:0015672 128 0.369
protein oligomerization GO:0051259 173 0.358
regulation of cell cycle GO:0051726 393 0.357
regulation of kinase activity GO:0043549 314 0.345
amine metabolic process GO:0009308 44 0.344
autophagic vacuole assembly GO:0000045 19 0.334
negative regulation of macroautophagy GO:0016242 4 0.331
regulation of cellular component biogenesis GO:0044087 281 0.322
regulation of cell migration GO:0030334 289 0.313
peptidyl tyrosine modification GO:0018212 170 0.305
regulation of protein kinase activity GO:0045859 289 0.295
post embryonic development GO:0009791 2 0.279
protein targeting GO:0006605 187 0.265
Yeast
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.261
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.260
negative regulation of protein metabolic process GO:0051248 391 0.259
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.253
response to growth factor GO:0070848 205 0.241
negative regulation of cell cycle g2 m phase transition GO:1902750 10 0.238
cellular ketone metabolic process GO:0042180 80 0.238
negative regulation of response to extracellular stimulus GO:0032105 5 0.235
interspecies interaction between organisms GO:0044419 156 0.230
regulation of viral release from host cell GO:1902186 20 0.230
regulation of autophagy GO:0010506 52 0.227
cellular response to nitrogen compound GO:1901699 144 0.225
cell cycle g2 m phase transition GO:0044839 43 0.222
growth of symbiont in host GO:0044117 1 0.217
mitotic cell cycle phase transition GO:0044772 162 0.216
positive regulation of adherens junction organization GO:1903393 12 0.216
protein localization to endoplasmic reticulum GO:0070972 19 0.210
regulation of cell matrix adhesion GO:0001952 42 0.203
cell cycle phase transition GO:0044770 173 0.201
positive regulation of locomotion GO:0040017 186 0.201
negative regulation of cell cycle GO:0045786 193 0.198
cytoplasmic transport GO:0016482 379 0.198
negative regulation of organelle assembly GO:1902116 7 0.196
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.196
viral release from host cell GO:0019076 21 0.187
regulation of viral process GO:0050792 103 0.186
regulation of vasodilation GO:0042312 4 0.184
regulation of exosomal secretion GO:1903541 12 0.182
jak stat cascade GO:0007259 46 0.182
cytokinesis GO:0000910 96 0.181
response to organonitrogen compound GO:0010243 156 0.179
receptor metabolic process GO:0043112 81 0.178
vasodilation GO:0042311 4 0.176
regulation of adherens junction organization GO:1903391 21 0.173
negative regulation of phosphate metabolic process GO:0045936 267 0.173
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.168
negative regulation of mitotic cell cycle GO:0045930 102 0.168
cellular response to starvation GO:0009267 58 0.166
regulation of cellular amino acid metabolic process GO:0006521 6 0.159
regulation of endothelial cell migration GO:0010594 67 0.158
response to peptide GO:1901652 65 0.156
positive regulation of viral release from host cell GO:1902188 5 0.155
activation of janus kinase activity GO:0042976 7 0.154
cellular response to endogenous stimulus GO:0071495 336 0.151
immune response activating signal transduction GO:0002757 90 0.151
positive regulation of gliogenesis GO:0014015 4 0.148
vesicle organization GO:0016050 62 0.145
Yeast
establishment of protein localization to endoplasmic reticulum GO:0072599 11 0.139
system process GO:0003008 349 0.138
morphogenesis of embryonic epithelium GO:0016331 4 0.138
macroautophagy GO:0016236 39 0.138
rho protein signal transduction GO:0007266 26 0.132
regulation of receptor mediated endocytosis GO:0048259 32 0.131
negative regulation of autophagy GO:0010507 14 0.131
mitotic cell cycle process GO:1903047 286 0.129
endocytosis GO:0006897 159 0.127
cellular amino acid metabolic process GO:0006520 116 0.126
protein localization to organelle GO:0033365 280 0.122
Yeast
epithelium development GO:0060429 227 0.120
regulation of cell adhesion mediated by integrin GO:0033628 22 0.119
cell matrix adhesion GO:0007160 85 0.114
regulation of cell cycle phase transition GO:1901987 126 0.113
peptidyl tyrosine phosphorylation GO:0018108 170 0.112
regulation of cell division GO:0051302 116 0.112
mitotic cell cycle checkpoint GO:0007093 68 0.111
positive regulation of glial cell proliferation GO:0060252 2 0.110
cell division GO:0051301 168 0.109
cellular macromolecule catabolic process GO:0044265 380 0.106
establishment of protein localization to membrane GO:0090150 121 0.106
positive regulation of developmental process GO:0051094 314 0.102
regulation of response to external stimulus GO:0032101 222 0.101
protein localization to membrane GO:0072657 160 0.099
negative regulation of cell motility GO:2000146 104 0.098
regulation of autophagic vacuole assembly GO:2000785 6 0.098
regulation of cell cycle process GO:0010564 266 0.095
regulation of receptor internalization GO:0002090 15 0.094
positive regulation of epithelial cell migration GO:0010634 55 0.094
modification dependent protein catabolic process GO:0019941 209 0.093
cell cycle checkpoint GO:0000075 117 0.093
negative regulation of response to external stimulus GO:0032102 83 0.093
regulation of neuron death GO:1901214 56 0.092
regulation of extracellular vesicular exosome assembly GO:1903551 4 0.092
erbb signaling pathway GO:0038127 44 0.092
Fly
regulation of cellular component movement GO:0051270 334 0.091
positive regulation of exocytosis GO:0045921 35 0.091
nucleotide catabolic process GO:0009166 408 0.090
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.089
negative regulation of cell cycle phase transition GO:1901988 89 0.089
negative regulation of cellular component organization GO:0051129 235 0.088
regulation of epithelial cell migration GO:0010632 93 0.088
positive regulation of cell matrix adhesion GO:0001954 23 0.087
positive regulation of viral process GO:0048524 37 0.087
regulation of cellular response to stress GO:0080135 244 0.086
associative learning GO:0008306 1 0.085
cell substrate adhesion GO:0031589 132 0.084
positive regulation of cellular component organization GO:0051130 376 0.084
regulation of mitotic cell cycle phase transition GO:1901990 118 0.084
cellular response to oxygen containing compound GO:1901701 276 0.081
positive regulation of organelle organization GO:0010638 195 0.081
epidermal growth factor receptor signaling pathway GO:0007173 39 0.081
Fly
negative regulation of cellular catabolic process GO:0031330 83 0.080
ribonucleoside triphosphate metabolic process GO:0009199 412 0.080
protein targeting to membrane GO:0006612 42 0.080
epithelial cell differentiation GO:0030855 141 0.079
tor signaling GO:0031929 39 0.079
regulation of transferase activity GO:0051338 355 0.079
response to extracellular stimulus GO:0009991 85 0.078
Yeast
negative regulation of neuron death GO:1901215 32 0.078
keratinocyte differentiation GO:0030216 36 0.078
protein targeting to er GO:0045047 7 0.076
cellular component morphogenesis GO:0032989 314 0.075
cellular response to hormone stimulus GO:0032870 125 0.074
positive regulation of phosphorylation GO:0042327 394 0.073
negative regulation of organelle organization GO:0010639 126 0.071
glycosyl compound catabolic process GO:1901658 413 0.071
positive regulation of cellular component movement GO:0051272 181 0.070
cation transport GO:0006812 331 0.070
mitotic cell cycle GO:0000278 326 0.069
response to transforming growth factor beta GO:0071559 94 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
cellular response to peptide hormone stimulus GO:0071375 56 0.068
vesicle mediated transport GO:0016192 371 0.068
cell substrate junction assembly GO:0007044 35 0.068
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.068
Yeast
cell adhesion GO:0007155 325 0.067
regulation of vesicle mediated transport GO:0060627 130 0.067
exosomal secretion GO:1990182 15 0.067
actin filament organization GO:0007015 128 0.066
regulation of protein tyrosine kinase activity GO:0061097 36 0.066
regulation of cell morphogenesis GO:0022604 153 0.066
negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 3 0.065
response to nitrogen compound GO:1901698 184 0.064
membrane protein proteolysis GO:0033619 38 0.064
potassium ion transport GO:0006813 62 0.064
negative regulation of response to nutrient levels GO:0032108 5 0.063
negative regulation of transport GO:0051051 176 0.063
regulation of organelle assembly GO:1902115 40 0.063
receptor mediated endocytosis GO:0006898 84 0.062
regulation of cell junction assembly GO:1901888 29 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.061
response to peptide hormone GO:0043434 61 0.061
regulation of erbb signaling pathway GO:1901184 27 0.061
Fly
negative regulation of protein modification process GO:0031400 200 0.061
organelle assembly GO:0070925 176 0.060
Fly
response to calcium ion GO:0051592 46 0.059
actin cytoskeleton organization GO:0030036 207 0.058
positive regulation of smooth muscle cell migration GO:0014911 6 0.056
epidermis development GO:0008544 59 0.056
negative regulation of cell division GO:0051782 31 0.056
secretion GO:0046903 254 0.056
metal ion transport GO:0030001 272 0.055
positive regulation of multi organism process GO:0043902 56 0.054
protein kinase b signaling GO:0043491 69 0.054
nucleoside catabolic process GO:0009164 408 0.054
positive regulation of cell migration GO:0030335 172 0.053
regulation of jak stat cascade GO:0046425 44 0.053
receptor transactivation GO:0035624 4 0.053
positive regulation of protein ubiquitination GO:0031398 53 0.052
negative regulation of intracellular signal transduction GO:1902532 183 0.052
regulation of multi organism process GO:0043900 157 0.052
protein polymerization GO:0051258 71 0.052
regulation of tor signaling GO:0032006 30 0.052
gtp catabolic process GO:0006184 237 0.051
regulation of actin cytoskeleton organization GO:0032956 116 0.051
regulation of cellular amine metabolic process GO:0033238 11 0.051
morphogenesis of a polarized epithelium GO:0001738 3 0.050
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.050
positive regulation of cellular amine metabolic process GO:0033240 7 0.050
positive regulation of cell adhesion GO:0045785 84 0.050
negative regulation of cell adhesion GO:0007162 64 0.049
regulation of epithelial cell proliferation GO:0050678 113 0.048
anatomical structure formation involved in morphogenesis GO:0048646 284 0.048
ribonucleotide catabolic process GO:0009261 405 0.048
cell chemotaxis GO:0060326 112 0.048
negative regulation of immune system process GO:0002683 136 0.047
neuron death GO:0070997 65 0.047
endothelial cell proliferation GO:0001935 65 0.045
regulation of cell motility GO:2000145 299 0.044
negative regulation of cell death GO:0060548 345 0.044
cellular protein complex assembly GO:0043623 188 0.043
positive regulation of transport GO:0051050 336 0.043
purine ribonucleotide catabolic process GO:0009154 404 0.043
memory GO:0007613 3 0.042
mitotic nuclear division GO:0007067 119 0.042
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.042
cell morphogenesis involved in differentiation GO:0000904 144 0.042
adult locomotory behavior GO:0008344 1 0.042
negative regulation of cell proliferation GO:0008285 228 0.042
regulation of vasculature development GO:1901342 97 0.042
circulatory system development GO:0072359 262 0.042
regulation of protein ubiquitination GO:0031396 95 0.041
regulation of endocytosis GO:0030100 72 0.041
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.041
chemical homeostasis GO:0048878 306 0.041
regulation of macroautophagy GO:0016241 19 0.041
guanosine containing compound catabolic process GO:1901069 239 0.041
adherens junction organization GO:0034332 36 0.041
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.041
positive regulation of focal adhesion assembly GO:0051894 11 0.041
activation of immune response GO:0002253 114 0.041
positive regulation of cell substrate adhesion GO:0010811 37 0.040
cellular response to organonitrogen compound GO:0071417 124 0.040
regulation of angiogenesis GO:0045765 92 0.040
synaptic vesicle endocytosis GO:0048488 2 0.039
spermatid differentiation GO:0048515 4 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
negative regulation of tor signaling GO:0032007 11 0.038
neuromuscular junction development GO:0007528 3 0.037
positive regulation of transferase activity GO:0051347 227 0.037
ubiquitin dependent protein catabolic process GO:0006511 206 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.036
angiogenesis GO:0001525 147 0.036
reactive oxygen species metabolic process GO:0072593 75 0.036
response to nutrient levels GO:0031667 81 0.036
Yeast
cellular response to external stimulus GO:0071496 111 0.036
immune system development GO:0002520 195 0.036
locomotory behavior GO:0007626 1 0.036
response to hormone GO:0009725 175 0.036
muscle cell migration GO:0014812 19 0.036
cytokinesis checkpoint GO:0031565 3 0.036
cellular anion homeostasis GO:0030002 4 0.036
positive regulation of synaptic transmission GO:0050806 4 0.035
immune response regulating signaling pathway GO:0002764 97 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.035
purine nucleoside catabolic process GO:0006152 398 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.034
regulation of cytokinesis GO:0032465 45 0.033
single organism cellular localization GO:1902580 332 0.033
Yeast
positive regulation of cell motility GO:2000147 177 0.033
positive regulation of platelet derived growth factor receptor signaling pathway GO:0010641 2 0.033
second messenger mediated signaling GO:0019932 78 0.033
regulation of immune response GO:0050776 201 0.033
maintenance of cell polarity GO:0030011 2 0.033
salivary gland morphogenesis GO:0007435 4 0.032
cellular response to nutrient levels GO:0031669 69 0.032
sequestering of calcium ion GO:0051208 17 0.032
protein dephosphorylation GO:0006470 81 0.032
regulation of reactive oxygen species metabolic process GO:2000377 41 0.032
short term memory GO:0007614 1 0.032
negative regulation of protein kinase activity GO:0006469 98 0.032
regulation of cell substrate adhesion GO:0010810 68 0.032
regulation of cytokine production GO:0001817 232 0.031
regulation of cell development GO:0060284 161 0.031
glycerolipid metabolic process GO:0046486 107 0.031
regulation of mapk cascade GO:0043408 262 0.031
cellular response to growth hormone stimulus GO:0071378 10 0.031
cardiovascular system development GO:0072358 262 0.031
cellular response to extracellular stimulus GO:0031668 72 0.031
regulation of potassium ion transport GO:0043266 24 0.031
response to steroid hormone GO:0048545 80 0.031
negative regulation of b cell receptor signaling pathway GO:0050859 2 0.031
positive regulation of cell development GO:0010720 92 0.030
negative regulation of cellular amine metabolic process GO:0033239 3 0.030
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.030
oogenesis GO:0048477 2 0.030
positive regulation of kinase activity GO:0033674 204 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
epithelial cell proliferation GO:0050673 128 0.029
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.029
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.029
central nervous system neuron axonogenesis GO:0021955 3 0.029
cell projection organization GO:0030030 252 0.029
negative regulation of kinase activity GO:0033673 106 0.029
response to lipid GO:0033993 206 0.029
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.029
cellular monovalent inorganic anion homeostasis GO:0030320 4 0.029
signal transduction by phosphorylation GO:0023014 297 0.028
actin filament based process GO:0030029 224 0.028
cell junction organization GO:0034330 79 0.028
regulation of cytoplasmic transport GO:1903649 149 0.028
negative regulation of axonogenesis GO:0050771 4 0.028
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.028
lens morphogenesis in camera type eye GO:0002089 2 0.028
response to retinoic acid GO:0032526 33 0.027
response to oxygen containing compound GO:1901700 369 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
regulation of rho gtpase activity GO:0032319 66 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.027
negative regulation of cell migration GO:0030336 102 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
multivesicular body organization GO:0036257 2 0.027
tissue remodeling GO:0048771 16 0.027
monovalent inorganic anion homeostasis GO:0055083 8 0.026
regulation of cell cycle g2 m phase transition GO:1902749 22 0.026
extracellular structure organization GO:0043062 41 0.026
positive regulation of protein complex assembly GO:0031334 86 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.025
cranial nerve development GO:0021545 4 0.025
bleb assembly GO:0032060 6 0.025
syncytium formation by plasma membrane fusion GO:0000768 2 0.025
response to abiotic stimulus GO:0009628 336 0.025
transmembrane transport GO:0055085 399 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
regulation of receptor activity GO:0010469 47 0.025
regulation of metal ion transport GO:0010959 120 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
epithelium migration GO:0090132 119 0.025
morphogenesis of an epithelium GO:0002009 60 0.024
immune response GO:0006955 307 0.024
Fly
divalent metal ion transport GO:0070838 152 0.024
regulation of rho protein signal transduction GO:0035023 79 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
secretion by cell GO:0032940 226 0.024
response to temperature stimulus GO:0009266 22 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
regulation of blood vessel size GO:0050880 18 0.024
epidermal cell differentiation GO:0009913 45 0.024
positive regulation of protein kinase activity GO:0045860 190 0.023
regulation of neurogenesis GO:0050767 82 0.023
oocyte development GO:0048599 1 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
regulation of cell growth GO:0001558 135 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
Fly
vasculature development GO:0001944 181 0.023
regulation of growth GO:0040008 165 0.023
Fly
biological adhesion GO:0022610 331 0.023
protein catabolic process GO:0030163 325 0.023
regeneration GO:0031099 4 0.023
regulation of clathrin mediated endocytosis GO:2000369 4 0.023
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.023
behavior GO:0007610 112 0.022
insulin receptor signaling pathway GO:0008286 23 0.022
growth hormone receptor signaling pathway GO:0060396 10 0.022
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 3 0.022
epithelial cell development GO:0002064 34 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
negative regulation of growth GO:0045926 97 0.022
blood vessel morphogenesis GO:0048514 162 0.022
response to starvation GO:0042594 59 0.021
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.021
protein tetramerization GO:0051262 47 0.021
neurotrophin trk receptor signaling pathway GO:0048011 4 0.021
positive regulation of endothelial cell proliferation GO:0001938 37 0.021
cellular response to insulin stimulus GO:0032869 41 0.021
regulation of glial cell proliferation GO:0060251 4 0.021
translation GO:0006412 132 0.021
actin polymerization or depolymerization GO:0008154 56 0.021
blastocyst development GO:0001824 3 0.020
toll signaling pathway GO:0008063 2 0.020
Fly
regulation of membrane potential GO:0042391 95 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
ameboidal type cell migration GO:0001667 135 0.020
regulation of cell adhesion GO:0030155 166 0.020
toxin transport GO:1901998 4 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.020
synaptic vesicle recycling GO:0036465 3 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
regulation of protein catabolic process GO:0042176 155 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
regulation of leukocyte chemotaxis GO:0002688 46 0.020
metal ion homeostasis GO:0055065 169 0.019
cellular protein catabolic process GO:0044257 261 0.019
protein autophosphorylation GO:0046777 123 0.019
tissue migration GO:0090130 119 0.019
focal adhesion assembly GO:0048041 30 0.019
epithelial to mesenchymal transition GO:0001837 48 0.019
regulation of secretion GO:0051046 194 0.019
regulation of vacuole organization GO:0044088 8 0.019
multivesicular body assembly GO:0036258 1 0.019
positive regulation of protein catabolic process GO:0045732 75 0.019
anatomical structure homeostasis GO:0060249 100 0.018
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 9 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.018
establishment of tissue polarity GO:0007164 3 0.018
negative regulation of growth of symbiont in host GO:0044130 1 0.018
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 2 0.018
calcium mediated signaling GO:0019722 44 0.018
immunoglobulin biosynthetic process GO:0002378 2 0.018
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
regulation of postsynaptic membrane potential GO:0060078 1 0.018
response to other organism GO:0051707 261 0.018
Fly
lens development in camera type eye GO:0002088 2 0.017
positive regulation of endocytosis GO:0045807 42 0.017
defense response GO:0006952 315 0.017
purine nucleotide catabolic process GO:0006195 405 0.017
myeloid cell differentiation GO:0030099 117 0.017
neuron development GO:0048666 113 0.017
cell projection assembly GO:0030031 126 0.017
neuron projection development GO:0031175 106 0.017
nerve development GO:0021675 4 0.017
positive regulation of exosomal secretion GO:1903543 12 0.017
response to external biotic stimulus GO:0043207 261 0.017
Fly
positive regulation of extracellular vesicular exosome assembly GO:1903553 4 0.017
regulation of endothelial cell proliferation GO:0001936 56 0.017
sequestering of metal ion GO:0051238 24 0.017
endothelial cell migration GO:0043542 86 0.017
cellular response to lipid GO:0071396 127 0.017
regulation of cgmp mediated signaling GO:0010752 1 0.017
dephosphorylation GO:0016311 209 0.017
regulation of response to dna damage stimulus GO:2001020 94 0.017
regulation of response to nutrient levels GO:0032107 22 0.016
regulation of lymphocyte activation GO:0051249 103 0.016
vascular process in circulatory system GO:0003018 29 0.016
positive regulation of cell cycle GO:0045787 140 0.016
positive regulation of phagocytosis GO:0050766 15 0.016
regulation of calcium mediated signaling GO:0050848 17 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
positive regulation of cell growth GO:0030307 48 0.016
leukocyte chemotaxis GO:0030595 76 0.016
dendritic spine morphogenesis GO:0060997 3 0.016
positive regulation of protein polymerization GO:0032273 45 0.016
innate immune response GO:0045087 178 0.016
response to insulin GO:0032868 45 0.016
negative regulation of locomotion GO:0040013 118 0.016
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.016
exocytosis GO:0006887 71 0.016
multicellular organismal aging GO:0010259 3 0.016
regulation of short term neuronal synaptic plasticity GO:0048172 1 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
establishment of planar polarity GO:0001736 3 0.016
regulation of smooth muscle cell migration GO:0014910 15 0.015
peptidyl tyrosine dephosphorylation GO:0035335 36 0.015
synaptic transmission GO:0007268 61 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of cell differentiation GO:0045595 393 0.015
regulation of neuronal synaptic plasticity GO:0048168 1 0.015
regulation of protein kinase b signaling GO:0051896 61 0.015
gtp metabolic process GO:0046039 239 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.015
motor neuron axon guidance GO:0008045 2 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
regulation of ion transmembrane transporter activity GO:0032412 72 0.015
smooth muscle cell proliferation GO:0048659 28 0.015
hindbrain development GO:0030902 3 0.015

PTPN23 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.971
eye and adnexa disease DOID:1492 150 0.971
nervous system disease DOID:863 431 0.971
eye disease DOID:5614 149 0.971
disease of cellular proliferation DOID:14566 174 0.124
disease of metabolism DOID:0014667 295 0.048
neuropathy DOID:870 52 0.037
central nervous system disease DOID:331 186 0.036
cancer DOID:162 167 0.032
organ system cancer DOID:0050686 164 0.029
neuromuscular disease DOID:440 38 0.024
muscular disease DOID:0080000 114 0.021
musculoskeletal system disease DOID:17 223 0.021
acquired metabolic disease DOID:0060158 58 0.020
myopathy DOID:423 104 0.020
muscle tissue disease DOID:66 113 0.020
breast cancer DOID:1612 21 0.018
thoracic cancer DOID:5093 21 0.018
neurodegenerative disease DOID:1289 102 0.018
charcot marie tooth disease DOID:10595 33 0.017