|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.997
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.996
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.993
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.992
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.989
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.989
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.989
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.986
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.982
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.981
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.978
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.976
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.973
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.971
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.964
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.960
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.958
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.952
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.941
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.930
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.927
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.907
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.888
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.888
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.867
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.846
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.829
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.825
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
10 |
0.815
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.803
|
Mouse |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.792
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.791
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.787
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.785
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.780
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.778
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.771
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.746
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.743
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.733
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.696
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.686
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.677
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.670
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.667
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.661
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.661
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.644
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.638
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.622
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.615
|
|
|
|
bone trabecula morphogenesis
|
GO:0061430 |
1 |
0.600
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.596
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.594
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.591
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.591
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.589
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.586
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.572
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.568
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.565
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.561
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.555
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.550
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.546
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.543
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.538
|
Mouse |
|
|
positive regulation of collateral sprouting
|
GO:0048672 |
2 |
0.534
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.529
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.528
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.519
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.503
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.494
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.488
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.484
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.484
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.483
|
Mouse |
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.474
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.468
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.460
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.458
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.455
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.451
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.432
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.431
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.428
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.428
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.417
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.415
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.415
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.412
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.392
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.390
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.390
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.386
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.385
|
Mouse |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.381
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.371
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.368
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.358
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.355
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.355
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.353
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.347
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.343
|
Mouse |
|
|
negative regulation of alkaline phosphatase activity
|
GO:0010693 |
2 |
0.337
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.334
|
Fly |
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.333
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.333
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.331
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.325
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.322
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.321
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.316
|
Fly |
|
|
cell activation
|
GO:0001775 |
213 |
0.308
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.307
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.303
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.296
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.296
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.295
|
Fly |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.291
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.289
|
Mouse |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.281
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.273
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.271
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.271
|
|
|
|
system process
|
GO:0003008 |
349 |
0.270
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.268
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.260
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.255
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.253
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.249
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.249
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.243
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.240
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.239
|
|
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.236
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.235
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.234
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.234
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.232
|
Fly |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.228
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.227
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.227
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.223
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.223
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.223
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.219
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.218
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.215
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.207
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.205
|
Mouse |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.205
|
Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.202
|
|
|
|
regulation of protein homodimerization activity
|
GO:0043496 |
9 |
0.197
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.197
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.192
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.191
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.190
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.184
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.182
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.181
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.177
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.176
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.173
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.172
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.172
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.171
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.170
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.169
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.167
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.163
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.162
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.161
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.157
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.157
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.154
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.154
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.150
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.149
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.145
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.144
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.141
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.140
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.139
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.137
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.137
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.136
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.136
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.136
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.135
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.134
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.133
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.133
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.132
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.132
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.129
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.127
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.126
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.124
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.123
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.122
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.120
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.119
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.117
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.116
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.116
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.115
|
Mouse |
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
19 |
0.114
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.113
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.110
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.109
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.109
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.108
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.108
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.108
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.107
|
|
|
|
neuron projection extension involved in neuron projection guidance
|
GO:1902284 |
5 |
0.107
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.107
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
4 |
0.107
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.105
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.101
|
Mouse |
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.100
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.100
|
|
|
|
growth
|
GO:0040007 |
202 |
0.100
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.099
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.099
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.098
|
|
|
|
positive regulation of cell adhesion mediated by integrin
|
GO:0033630 |
9 |
0.098
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.097
|
Fly |
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
20 |
0.096
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.096
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.095
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.094
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.093
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.093
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.093
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.093
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.092
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.092
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.092
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.092
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.092
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.091
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.089
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.089
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.088
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.088
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.088
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.087
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.086
|
|
|
|
regulation of interleukin 4 production
|
GO:0032673 |
7 |
0.085
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.085
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.085
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.084
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.084
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.084
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.084
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.083
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.083
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.082
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.081
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.080
|
Mouse |
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.080
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.080
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.079
|
|
|
|
calcium ion import
|
GO:0070509 |
23 |
0.079
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.079
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.078
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.078
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.078
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.078
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.077
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.077
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.076
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.076
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.076
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.074
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.074
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.074
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.074
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.074
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.073
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.073
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.073
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.073
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.071
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.071
|
Mouse |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.071
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.070
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.069
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.068
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.068
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.068
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.067
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.067
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.066
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.066
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.066
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.066
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.066
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.066
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.065
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.064
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.064
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.064
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.064
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.063
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.063
|
Mouse |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.062
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.062
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.062
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.062
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.062
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.062
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.061
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.060
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.060
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.059
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.059
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.058
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.058
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.058
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.058
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.057
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.057
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.056
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.055
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.055
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.055
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.055
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.054
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.054
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.054
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.054
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.053
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.052
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.050
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.050
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.050
|
|
|
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
4 |
0.049
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.049
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.049
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.049
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.049
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.048
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.048
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.048
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.047
|
Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.047
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.047
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.047
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.047
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.047
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.046
|
|
|
|
head development
|
GO:0060322 |
108 |
0.045
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.045
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.045
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.045
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.045
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.044
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.044
|
Mouse |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.043
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.043
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.043
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.043
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.043
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
9 |
0.042
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.041
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.041
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.041
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.041
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.041
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.041
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.040
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.040
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.040
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.040
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.039
|
Mouse |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.039
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.039
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.039
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.038
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
Mouse |
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.038
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.037
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.037
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.037
|
|
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.036
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.036
|
Mouse |
|
|
positive regulation of establishment of protein localization to plasma membrane
|
GO:0090004 |
18 |
0.036
|
|
|
|
exocrine system development
|
GO:0035272 |
7 |
0.036
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.036
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.036
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.035
|
Rat |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.035
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.035
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.035
|
Mouse |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.035
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.034
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.034
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.034
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.034
|
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.034
|
Mouse |
|
|
regeneration
|
GO:0031099 |
4 |
0.034
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.034
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.034
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.034
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
|
|
|
regulation of collateral sprouting
|
GO:0048670 |
2 |
0.033
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.033
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.033
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.032
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.032
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.032
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.032
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.032
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.032
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.031
|
Mouse |
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.031
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.031
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.031
|
|
|
|
positive t cell selection
|
GO:0043368 |
2 |
0.031
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.031
|
|
|
|
ectodermal cell differentiation
|
GO:0010668 |
3 |
0.031
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.030
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.030
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.030
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
22 |
0.030
|
|
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
23 |
0.030
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.030
|
Rat |
|
|
developmental growth
|
GO:0048589 |
48 |
0.030
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.030
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.030
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.029
|
Mouse |
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.029
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.029
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.029
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.029
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.029
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.029
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.028
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.028
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.028
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.028
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.028
|
|
|
|
eosinophil chemotaxis
|
GO:0048245 |
8 |
0.028
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.028
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.028
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.028
|
Fly |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.028
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.028
|
|
|
|
cell cell adhesion
|
GO:0098609 |
19 |
0.028
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.027
|
|
|
|
mating
|
GO:0007618 |
1 |
0.027
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.027
|
|
|
|
bone maturation
|
GO:0070977 |
5 |
0.027
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.027
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.026
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.026
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.026
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.026
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.026
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.026
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.026
|
Mouse |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.026
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.026
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.026
|
Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.026
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.026
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.025
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.025
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.025
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.025
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.025
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.025
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.024
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.024
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.024
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.024
|
|
|
|
receptor clustering
|
GO:0043113 |
9 |
0.024
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.024
|
|
|
|
positive regulation of dephosphorylation
|
GO:0035306 |
26 |
0.024
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.024
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.023
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.023
|
Mouse |
|
|
organ maturation
|
GO:0048799 |
5 |
0.023
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.023
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.023
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.022
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.022
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.022
|
|
