|
|
parturition
|
GO:0007567 |
1 |
0.512
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.511
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.481
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.474
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.434
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.399
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.374
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.373
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.349
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.314
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.303
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.293
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.284
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.282
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.274
|
Worm |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.272
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.265
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.242
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.241
|
Human Zebrafish Rat Worm Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.237
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.236
|
Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.233
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.226
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.219
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.211
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.211
|
Human Zebrafish Worm Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.208
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.207
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.207
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.201
|
Human Zebrafish Rat Worm Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.199
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.196
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.195
|
Human Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.194
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.192
|
Human Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.190
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.188
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.179
|
Rat |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.178
|
|
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.177
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.177
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.176
|
|
|
|
negative regulation of pinocytosis
|
GO:0048550 |
4 |
0.175
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.174
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.172
|
Human Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.168
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.168
|
Human Zebrafish Worm Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.165
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.165
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.165
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.152
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.151
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.148
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.147
|
Human Rat Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.143
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.142
|
|
|
|
receptor internalization involved in canonical wnt signaling pathway
|
GO:2000286 |
3 |
0.141
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.141
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.138
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.134
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.134
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.133
|
Mouse Rat Fly |
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.130
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.129
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.128
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.128
|
Rat |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.128
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.126
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.126
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.125
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.123
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.123
|
Human Zebrafish Rat Worm Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.119
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.119
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.118
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.118
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.117
|
Human Rat |
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
10 |
0.116
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.116
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.116
|
Rat |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.115
|
|
|
|
regulation of pinocytosis
|
GO:0048548 |
6 |
0.114
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.113
|
Human Rat Fly |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.113
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.113
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.112
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.111
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.111
|
Human Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.110
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.110
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.109
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.106
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.106
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.106
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.104
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.103
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.103
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.101
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
1 |
0.100
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.100
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.099
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
6 |
0.098
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.096
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.095
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.093
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.093
|
|
|
|
system process
|
GO:0003008 |
349 |
0.093
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.092
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.092
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.091
|
|
|
|
mating
|
GO:0007618 |
1 |
0.090
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.089
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.089
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.088
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.087
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.087
|
Fly |
|
|
startle response
|
GO:0001964 |
3 |
0.085
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.085
|
Human Rat Fly |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.084
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.083
|
|
|
|
regulation of dopamine receptor signaling pathway
|
GO:0060159 |
3 |
0.083
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.082
|
Rat |
|
|
vasculature development
|
GO:0001944 |
181 |
0.082
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.081
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.080
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.080
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.080
|
Worm |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.080
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.080
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.079
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.078
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.077
|
Rat |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.077
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.077
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.077
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.076
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.076
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.076
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.075
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.075
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.074
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.073
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.073
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.073
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.072
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.072
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.071
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.071
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.071
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.070
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.070
|
Fly |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.069
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
2 |
0.069
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.069
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.068
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.068
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.068
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.068
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.068
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.067
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.067
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.067
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.067
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.067
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.065
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.065
|
Human |
|
|
coagulation
|
GO:0050817 |
78 |
0.065
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.065
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.064
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.064
|
Rat |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.063
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.063
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.063
|
|
|
|
positive regulation of g protein coupled receptor protein signaling pathway
|
GO:0045745 |
9 |
0.063
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.062
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.062
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.062
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.062
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.061
|
Human Rat |
|
|
sterol transport
|
GO:0015918 |
39 |
0.060
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.060
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.060
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.059
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.059
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.059
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.059
|
|
|
|
growth
|
GO:0040007 |
202 |
0.059
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.058
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.057
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.057
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.057
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.057
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.057
|
Fly |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.055
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.055
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.055
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.055
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.055
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.055
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.055
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.054
|
Rat |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.054
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.054
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.053
|
Rat |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.053
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.053
|
Human Rat |
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.053
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.052
|
Human |
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.052
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.052
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.052
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.051
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.051
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.051
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.050
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.050
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.050
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.050
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.049
|
Worm |
|
|
response to hormone
|
GO:0009725 |
175 |
0.049
|
Rat |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.049
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.049
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.049
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.049
|
Rat |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.049
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.048
|
Human |
|
|
negative regulation of nitric oxide biosynthetic process
|
GO:0045019 |
5 |
0.048
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.048
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.048
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.047
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.047
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.047
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.047
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.047
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.046
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.046
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.046
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.046
|
|
|
|
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure
|
GO:0001999 |
1 |
0.046
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.046
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.046
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.045
|
|
|
|
endoplasmic reticulum organization
|
GO:0007029 |
20 |
0.045
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.045
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.045
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.045
|
|
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.045
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.044
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.044
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.044
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.044
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.044
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.044
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.044
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.043
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.043
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.043
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.043
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.043
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.043
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.043
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.043
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.042
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.042
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.042
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.042
|
Human Rat |
|
|
immune response
|
GO:0006955 |
307 |
0.041
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.041
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.041
|
Human Zebrafish Rat Worm Fly |
|
|
neuron development
|
GO:0048666 |
113 |
0.041
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.041
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.041
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.041
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.041
|
Human Fly |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.040
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.040
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.040
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.040
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.040
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.040
|
Worm |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.040
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.039
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.039
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.039
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.039
|
Human Rat |
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.039
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.039
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.039
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.039
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.038
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.038
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.038
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.038
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.038
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.037
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.037
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.037
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.037
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.037
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.037
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.037
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.037
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.037
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.036
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.036
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.036
|
Human |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.036
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.035
|
Human |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.035
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.035
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.035
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.035
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.035
|
Worm Fly |
|
|
vesicle docking
|
GO:0048278 |
5 |
0.035
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.035
|
|
|
|
intestinal cholesterol absorption
|
GO:0030299 |
4 |
0.035
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.034
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.034
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.034
|
Fly |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.034
|
Fly |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.034
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.034
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.034
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.034
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.034
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.033
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.033
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.033
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.033
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.033
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.032
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.032
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.032
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.032
|
Mouse |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.032
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.032
|
Human Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.032
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.032
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.032
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.032
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.032
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.032
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.031
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.031
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.031
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.031
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.031
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.031
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.031
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.031
|
Human Zebrafish Rat Worm Fly |
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.031
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.030
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.030
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.030
|
|
|
|
memory
|
GO:0007613 |
3 |
0.030
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.030
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.030
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.030
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.030
|
|
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.030
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.030
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.030
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.030
|
|
|
|
regulation of neutrophil mediated killing of bacterium
|
GO:0070950 |
1 |
0.030
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.030
|
Human Zebrafish Worm Fly |
|
|
head development
|
GO:0060322 |
108 |
0.030
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.030
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.029
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.029
|
Human Zebrafish Mouse Worm Fly |
|
|
behavior
|
GO:0007610 |
112 |
0.029
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.029
|
Rat Fly |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.029
|
Human |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.029
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.029
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.029
|
Human Rat |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.029
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.029
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.029
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.029
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.029
|
Human |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.029
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.029
|
Rat |
|
|
pinocytosis
|
GO:0006907 |
8 |
0.029
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.028
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.028
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.028
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.028
|
|
|
|
catagen
|
GO:0042637 |
3 |
0.028
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.028
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.028
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.028
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.028
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.028
|
Mouse Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.028
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
platelet formation
|
GO:0030220 |
4 |
0.027
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.027
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.027
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.027
|
Mouse Rat Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.027
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.027
|
Human |
|
|
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016339 |
2 |
0.027
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.027
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.027
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.027
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.027
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.027
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.027
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.027
|
Rat |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.027
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.027
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.027
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.026
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.026
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.026
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.026
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.026
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.026
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.026
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.026
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.026
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.026
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.026
|
|
|
|
regulation of eosinophil activation
|
GO:1902566 |
2 |
0.026
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.026
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.026
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.026
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.026
|
Rat |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.026
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.026
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.026
|
|
|
|
negative regulation of catagen
|
GO:0051796 |
1 |
0.026
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.026
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.025
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.025
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.025
|
Rat |
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.025
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.025
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.025
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.025
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.025
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.025
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.025
|
Fly |
|
|
transcription initiation from rna polymerase i promoter
|
GO:0006361 |
2 |
0.025
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.025
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.025
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.025
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.025
|
Rat |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.025
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.025
|
Worm |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.025
|
Mouse Rat Fly |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.025
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.025
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.025
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.024
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.024
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.024
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.024
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.024
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.024
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.024
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.024
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.024
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.024
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.024
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.023
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
2 |
0.023
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.023
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.023
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
7 |
0.023
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.023
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.023
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.023
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.023
|
|
|
|
regulation of neutrophil mediated killing of gram negative bacterium
|
GO:0070951 |
1 |
0.023
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.023
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.023
|
|
