Homo sapiens

205 known processes

PTPRJ

protein tyrosine phosphatase, receptor type, J

(Aliases: R-PTP-ETA,SCC1,HPTPeta,DEP1,CD148)

PTPRJ biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.995
branching involved in salivary gland morphogenesis GO:0060445 1 0.963
salivary gland morphogenesis GO:0007435 4 0.958
cell junction maintenance GO:0034331 4 0.939
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.937
response to cytokine GO:0034097 232 0.924
mesendoderm development GO:0048382 1 0.916
regulation of branching involved in salivary gland morphogenesis GO:0060693 1 0.897
negative regulation of catagen GO:0051796 1 0.889
regulation of cell motility GO:2000145 299 0.880
small gtpase mediated signal transduction GO:0007264 78 0.823
photoreceptor cell differentiation GO:0046530 2 0.805
cytokine mediated signaling pathway GO:0019221 109 0.801
regulation of cellular component movement GO:0051270 334 0.797
activation of mapk activity GO:0000187 45 0.780
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.775
regulation of ras protein signal transduction GO:0046578 155 0.759
inactivation of mapk activity GO:0000188 5 0.758
cellular amine metabolic process GO:0044106 41 0.749
regulation of map kinase activity GO:0043405 108 0.738
regulation of melanosome transport GO:1902908 1 0.697
regulation of anatomical structure morphogenesis GO:0022603 286 0.665
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.662
muscle contraction GO:0006936 73 0.649
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling GO:0060665 1 0.628
catagen GO:0042637 3 0.623
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.610
melanin biosynthetic process GO:0042438 1 0.578
response to nitrosative stress GO:0051409 4 0.576
secondary metabolite biosynthetic process GO:0044550 2 0.572
regulation of muscle contraction GO:0006937 45 0.572
regulation of system process GO:0044057 101 0.570
regulation of muscle system process GO:0090257 53 0.563
circulatory system process GO:0003013 113 0.561
cardiac muscle cell contraction GO:0086003 4 0.560
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.549
keratinization GO:0031424 2 0.547
desmosome assembly GO:0002159 4 0.542
regulation of cell migration GO:0030334 289 0.534
cardiac muscle cell action potential GO:0086001 23 0.528
regulation of canonical wnt signaling pathway GO:0060828 88 0.523
stress activated protein kinase signaling cascade GO:0031098 94 0.520
negative regulation of wnt signaling pathway GO:0030178 69 0.519
regulation of neuron migration GO:2001222 3 0.516
positive regulation of map kinase activity GO:0043406 80 0.508
peptidyl tyrosine phosphorylation GO:0018108 170 0.498
sprouting angiogenesis GO:0002040 29 0.496
cellular response to cytokine stimulus GO:0071345 181 0.491
peptidyl tyrosine dephosphorylation GO:0035335 36 0.482
immune response regulating signaling pathway GO:0002764 97 0.480
negative regulation of apoptotic process GO:0043066 316 0.472
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.471
positive regulation of cell cycle GO:0045787 140 0.468
regulation of mapk cascade GO:0043408 262 0.461
cell chemotaxis GO:0060326 112 0.444
Human Mouse
mitotic cell cycle GO:0000278 326 0.443
regulation of protein serine threonine kinase activity GO:0071900 179 0.437
positive regulation of endothelial cell migration GO:0010595 39 0.436
organophosphate catabolic process GO:0046434 430 0.435
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.428
biological adhesion GO:0022610 331 0.424
positive regulation of gtpase activity GO:0043547 166 0.421
circulatory system development GO:0072359 262 0.420
Mouse
purine nucleotide catabolic process GO:0006195 405 0.419
regulation of blood circulation GO:1903522 59 0.415
skin development GO:0043588 76 0.413
low density lipoprotein particle mediated signaling GO:0055096 1 0.412
muscle tissue development GO:0060537 62 0.411
cellular amino acid metabolic process GO:0006520 116 0.398
regulation of protein localization GO:0032880 296 0.390
purine ribonucleoside metabolic process GO:0046128 437 0.390
cellular response to organonitrogen compound GO:0071417 124 0.390
regulation of protein kinase activity GO:0045859 289 0.389
cellular response to nitrogen compound GO:1901699 144 0.386
ribonucleoside triphosphate catabolic process GO:0009203 391 0.382
single organismal cell cell adhesion GO:0016337 148 0.379
tor signaling GO:0031929 39 0.378
semaphorin plexin signaling pathway GO:0071526 4 0.377
positive regulation of natural killer cell activation GO:0032816 8 0.373
tissue migration GO:0090130 119 0.372
blood circulation GO:0008015 113 0.370
positive regulation of gtp catabolic process GO:0033126 166 0.369
purine nucleoside triphosphate metabolic process GO:0009144 412 0.363
positive regulation of cell division GO:0051781 59 0.363
regulation of cell differentiation GO:0045595 393 0.361
response to organonitrogen compound GO:0010243 156 0.356
regulation of erk1 and erk2 cascade GO:0070372 99 0.344
vasculature development GO:0001944 181 0.343
Mouse
muscle system process GO:0003012 81 0.342
ras protein signal transduction GO:0007265 73 0.341
ribonucleotide catabolic process GO:0009261 405 0.326
purine ribonucleotide catabolic process GO:0009154 404 0.324
cytosolic calcium ion homeostasis GO:0051480 89 0.321
epithelium migration GO:0090132 119 0.319
metal ion homeostasis GO:0055065 169 0.316
regulation of cell cycle GO:0051726 393 0.312
lipid metabolic process GO:0006629 381 0.309
regulation of transferase activity GO:0051338 355 0.308
response to hormone GO:0009725 175 0.308
response to lipid GO:0033993 206 0.306
regulation of cellular amine metabolic process GO:0033238 11 0.305
calcium mediated signaling GO:0019722 44 0.297
positive regulation of transport GO:0051050 336 0.294
dendritic cell apoptotic process GO:0097048 4 0.292
cell junction organization GO:0034330 79 0.289
positive regulation of protein transport GO:0051222 135 0.287
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.287
epithelial cell migration GO:0010631 119 0.283
cellular response to endogenous stimulus GO:0071495 336 0.282
canonical wnt signaling pathway GO:0060070 116 0.280
epidermis development GO:0008544 59 0.279
single organism cellular localization GO:1902580 332 0.278
response to other organism GO:0051707 261 0.277
signal transduction by phosphorylation GO:0023014 297 0.277
response to nitrogen compound GO:1901698 184 0.276
positive regulation of response to external stimulus GO:0032103 88 0.274
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.268
cell adhesion GO:0007155 325 0.267
regulation of melanin biosynthetic process GO:0048021 1 0.266
nuclear transport GO:0051169 179 0.260
regulation of epithelial cell migration GO:0010632 93 0.260
regulation of heart contraction GO:0008016 50 0.259
heart process GO:0003015 62 0.257
positive regulation of phosphorylation GO:0042327 394 0.256
regulation of wnt signaling pathway GO:0030111 123 0.255
ameboidal type cell migration GO:0001667 135 0.253
regulation of nucleotide metabolic process GO:0006140 269 0.251
dna replication GO:0006260 116 0.251
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.251
regulation of protein transport GO:0051223 213 0.251
gtp metabolic process GO:0046039 239 0.243
regulation of establishment of protein localization GO:0070201 242 0.242
guanosine containing compound metabolic process GO:1901068 244 0.242
cellular lipid metabolic process GO:0044255 303 0.241
dephosphorylation GO:0016311 209 0.239
regulation of kinase activity GO:0043549 314 0.233
negative regulation of cell adhesion GO:0007162 64 0.233
regulation of cellular amino acid metabolic process GO:0006521 6 0.232
cell activation GO:0001775 213 0.230
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.230
negative regulation of multicellular organismal process GO:0051241 317 0.230
Worm
endothelial cell migration GO:0043542 86 0.230
regulation of cardiac muscle cell contraction GO:0086004 23 0.226
response to biotic stimulus GO:0009607 276 0.226
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.223
regulation of cellular response to stress GO:0080135 244 0.222
erk1 and erk2 cascade GO:0070371 104 0.221
negative regulation of erk1 and erk2 cascade GO:0070373 14 0.220
wnt signaling pathway GO:0016055 156 0.219
positive regulation of nucleoside metabolic process GO:0045979 186 0.219
response to growth factor GO:0070848 205 0.215
morphogenesis of a polarized epithelium GO:0001738 3 0.215
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.214
regulation of small gtpase mediated signal transduction GO:0051056 156 0.214
purine nucleoside catabolic process GO:0006152 398 0.214
cell cell junction organization GO:0045216 69 0.213
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.210
multicellular organismal signaling GO:0035637 34 0.209
positive regulation of mapk cascade GO:0043410 190 0.209
regulation of nucleoside metabolic process GO:0009118 209 0.208
positive regulation of catabolic process GO:0009896 310 0.208
cytoplasmic transport GO:0016482 379 0.207
response to oxygen containing compound GO:1901700 369 0.207
negative regulation of programmed cell death GO:0043069 321 0.206
mitotic cell cycle process GO:1903047 286 0.206
myeloid cell differentiation GO:0030099 117 0.206
cellular response to inorganic substance GO:0071241 45 0.205
cellular response to hormone stimulus GO:0032870 125 0.204
heart contraction GO:0060047 62 0.203
response to oxidative stress GO:0006979 121 0.202
enzyme linked receptor protein signaling pathway GO:0007167 303 0.201
nucleoside phosphate catabolic process GO:1901292 412 0.201
innate immune response GO:0045087 178 0.201
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.200
single organism cell adhesion GO:0098602 179 0.198
regulation of locomotion GO:0040012 329 0.195
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.194
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.194
lipoprotein particle mediated signaling GO:0055095 1 0.193
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.192
positive regulation of hydrolase activity GO:0051345 331 0.190
smooth muscle cell proliferation GO:0048659 28 0.189
activation of protein kinase activity GO:0032147 90 0.187
oligodendrocyte development GO:0014003 6 0.187
mesenchymal epithelial cell signaling GO:0060638 1 0.186
nucleotide catabolic process GO:0009166 408 0.185
regulation of stress activated mapk cascade GO:0032872 84 0.185
cellular divalent inorganic cation homeostasis GO:0072503 128 0.184
response to organic cyclic compound GO:0014070 204 0.184
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.183
actin mediated cell contraction GO:0070252 12 0.181
regulation of purine nucleotide catabolic process GO:0033121 205 0.181
immune response GO:0006955 307 0.179
rho protein signal transduction GO:0007266 26 0.173
cell morphogenesis GO:0000902 296 0.173
Fly
cellular response to growth factor stimulus GO:0071363 197 0.172
regulation of dendritic cell apoptotic process GO:2000668 4 0.171
cell cell signaling GO:0007267 155 0.170
cellular chemical homeostasis GO:0055082 180 0.170
purine nucleoside triphosphate catabolic process GO:0009146 392 0.169
nucleoside catabolic process GO:0009164 408 0.169
nucleoside triphosphate metabolic process GO:0009141 422 0.167
cellular calcium ion homeostasis GO:0006874 117 0.167
secretion by cell GO:0032940 226 0.165
cellular metal ion homeostasis GO:0006875 146 0.164
actin filament based movement GO:0030048 17 0.164
regulation of smooth muscle cell proliferation GO:0048660 28 0.164
regulation of cytokine production GO:0001817 232 0.164
regulation of jnk cascade GO:0046328 73 0.163
negative regulation of developmental process GO:0051093 247 0.163
Worm
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.163
pituitary gland development GO:0021983 2 0.158
ribonucleoside triphosphate metabolic process GO:0009199 412 0.158
regulation of apoptotic signaling pathway GO:2001233 175 0.156
second messenger mediated signaling GO:0019932 78 0.151
purine ribonucleoside catabolic process GO:0046130 398 0.150
response to reactive oxygen species GO:0000302 61 0.149
positive regulation of jnk cascade GO:0046330 52 0.147
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.146
epidermal cell differentiation GO:0009913 45 0.146
regulation of gtpase activity GO:0043087 180 0.146
mapk cascade GO:0000165 288 0.145
cellular homeostasis GO:0019725 196 0.143
regulation of cell substrate adhesion GO:0010810 68 0.142
response to low density lipoprotein particle GO:0055098 4 0.142
negative regulation of phosphorus metabolic process GO:0010563 267 0.142
cellular response to oxygen containing compound GO:1901701 276 0.142
regulation of cardiac muscle contraction GO:0055117 33 0.141
guanosine containing compound catabolic process GO:1901069 239 0.140
protein import into nucleus GO:0006606 104 0.139
regulation of intracellular transport GO:0032386 195 0.136
action potential GO:0001508 34 0.135
positive regulation of rho gtpase activity GO:0032321 56 0.135
mast cell degranulation GO:0043303 4 0.134
calcium ion homeostasis GO:0055074 122 0.134
striated muscle tissue development GO:0014706 59 0.134
histone modification GO:0016570 251 0.133
positive regulation of cell cycle process GO:0090068 106 0.130
bmp signaling pathway GO:0030509 49 0.129
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.127
cell junction assembly GO:0034329 67 0.126
gland morphogenesis GO:0022612 8 0.126
arachidonic acid metabolic process GO:0019369 14 0.125
response to peptide GO:1901652 65 0.125
cardiac conduction GO:0061337 23 0.124
gtp catabolic process GO:0006184 237 0.124
protein targeting GO:0006605 187 0.123
cell matrix adhesion GO:0007160 85 0.122
nucleocytoplasmic transport GO:0006913 176 0.122
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.122
regulation of endothelial cell differentiation GO:0045601 4 0.122
cation transport GO:0006812 331 0.122
negative regulation of protein kinase activity GO:0006469 98 0.121
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.120
ventricular cardiac muscle cell action potential GO:0086005 15 0.120
positive regulation of cellular component organization GO:0051130 376 0.120
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.120
negative regulation of wound healing GO:0061045 25 0.118
regulation of hair follicle maturation GO:0048819 3 0.117
regulation of body fluid levels GO:0050878 99 0.117
Mouse
regulation of response to osmotic stress GO:0047484 3 0.117
chromatin modification GO:0016568 298 0.117
epithelium development GO:0060429 227 0.116
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.116
activation of immune response GO:0002253 114 0.115
vesicle mediated transport GO:0016192 371 0.115
response to abiotic stimulus GO:0009628 336 0.113
cell communication involved in cardiac conduction GO:0086065 18 0.113
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.113
system process GO:0003008 349 0.113
myoblast proliferation GO:0051450 1 0.112
cellular ion homeostasis GO:0006873 168 0.112
positive chemotaxis GO:0050918 33 0.111
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.110
behavior GO:0007610 112 0.110
Mouse Fly
actin filament based process GO:0030029 224 0.109
cell type specific apoptotic process GO:0097285 125 0.109
single organism nuclear import GO:1902593 104 0.109
histone acetylation GO:0016573 93 0.108
regulation of chemotaxis GO:0050920 74 0.108
Mouse
regulation of stem cell differentiation GO:2000736 56 0.108
positive regulation of protein phosphorylation GO:0001934 313 0.108
response to estradiol GO:0032355 23 0.108
nuclear import GO:0051170 106 0.107
positive regulation of cellular amine metabolic process GO:0033240 7 0.107
cell cell adhesion involved in gastrulation GO:0070586 6 0.106
positive regulation of protein kinase b signaling GO:0051897 42 0.106
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.106
regulation of membrane potential GO:0042391 95 0.106
positive regulation of focal adhesion assembly GO:0051894 11 0.105
response to external biotic stimulus GO:0043207 261 0.104
chromatin organization GO:0006325 351 0.104
calcium ion transport GO:0006816 147 0.104
regulation of rho protein signal transduction GO:0035023 79 0.103
blastocyst formation GO:0001825 3 0.102
epiboly involved in gastrulation with mouth forming second GO:0055113 1 0.101
male gonad development GO:0008584 23 0.101
internal peptidyl lysine acetylation GO:0018393 97 0.101
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.101
negative regulation of hair follicle development GO:0051799 1 0.100
regulation of endocytosis GO:0030100 72 0.096
response to inorganic substance GO:0010035 127 0.096
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.095
keratinocyte differentiation GO:0030216 36 0.095
fc receptor signaling pathway GO:0038093 2 0.094
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.094
covalent chromatin modification GO:0016569 254 0.094
regulation of gtp catabolic process GO:0033124 180 0.094
regulation of intracellular protein transport GO:0033157 123 0.093
positive regulation of cell migration GO:0030335 172 0.093
Mouse
purine containing compound catabolic process GO:0072523 411 0.093
ribonucleoside catabolic process GO:0042454 406 0.093
positive regulation of cell adhesion GO:0045785 84 0.093
cellular response to peptide hormone stimulus GO:0071375 56 0.093
epithelial cell differentiation GO:0030855 141 0.092
negative regulation of cellular protein metabolic process GO:0032269 353 0.092
negative regulation of transforming growth factor beta2 production GO:0032912 2 0.092
regulation of actin filament based movement GO:1903115 24 0.091
positive regulation of melanosome transport GO:1902910 1 0.090
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.090
pigment granule localization GO:0051875 7 0.089
regulation of heart rate GO:0002027 38 0.089
response to peptide hormone GO:0043434 61 0.089
erbb signaling pathway GO:0038127 44 0.088
cell migration involved in gastrulation GO:0042074 1 0.088
hematopoietic progenitor cell differentiation GO:0002244 38 0.088
defense response GO:0006952 315 0.087
regulation of striated muscle contraction GO:0006942 37 0.087
positive regulation of stress activated mapk cascade GO:0032874 60 0.087
embryonic placenta development GO:0001892 1 0.086
cation transmembrane transport GO:0098655 238 0.086
cellular response to reactive oxygen species GO:0034614 50 0.086
embryonic epithelial tube formation GO:0001838 4 0.085
negative regulation of phosphate metabolic process GO:0045936 267 0.085
cardiac muscle tissue development GO:0048738 39 0.085
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.084
regulation of cellular ketone metabolic process GO:0010565 50 0.083
regulation of cell activation GO:0050865 125 0.083
Mouse
response to lipopolysaccharide GO:0032496 70 0.082
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.082
amine metabolic process GO:0009308 44 0.082
hemopoiesis GO:0030097 180 0.081
post embryonic development GO:0009791 2 0.081
Worm
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.081
determination of adult lifespan GO:0008340 2 0.080
ion homeostasis GO:0050801 230 0.080
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.080
glycerophospholipid metabolic process GO:0006650 84 0.079
cation homeostasis GO:0055080 189 0.079
regulation of immune response GO:0050776 201 0.079
chemical homeostasis GO:0048878 306 0.079
reproductive structure development GO:0048608 55 0.078
peptidyl lysine acetylation GO:0018394 101 0.078
protein acetylation GO:0006473 116 0.077
negative regulation of hemostasis GO:1900047 22 0.077
positive regulation of nucleotide metabolic process GO:0045981 230 0.077
phosphatidylinositol mediated signaling GO:0048015 55 0.076
programmed cell death in response to reactive oxygen species GO:0097468 4 0.076
cellular response to dna damage stimulus GO:0006974 379 0.075
positive regulation of wound healing GO:0090303 20 0.075
Mouse
regulation of cytokinesis GO:0032465 45 0.075
immune response activating signal transduction GO:0002757 90 0.075
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 0.074
cell division GO:0051301 168 0.074
negative regulation of blood coagulation GO:0030195 22 0.074
divalent inorganic cation transport GO:0072511 158 0.074
negative regulation of cellular amine metabolic process GO:0033239 3 0.074
regulation of postsynaptic membrane potential GO:0060078 1 0.073
endothelial cell chemotaxis GO:0035767 13 0.073
locomotory behavior GO:0007626 1 0.073
neural tube formation GO:0001841 3 0.072
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.072
regulation of hydrogen peroxide mediated programmed cell death GO:1901298 4 0.071
transmembrane transport GO:0055085 399 0.071
gastrulation with mouth forming second GO:0001702 1 0.071
sensory perception of pain GO:0019233 4 0.071
hair follicle maturation GO:0048820 3 0.070
cartilage condensation GO:0001502 1 0.069
antigen receptor mediated signaling pathway GO:0050851 38 0.069
positive regulation of organelle organization GO:0010638 195 0.069
regulation of cellular response to growth factor stimulus GO:0090287 76 0.068
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.068
regulation of secretion by cell GO:1903530 177 0.068
secretion GO:0046903 254 0.067
regulation of protein export from nucleus GO:0046825 15 0.067
negative regulation of phosphorylation GO:0042326 174 0.067
development of primary male sexual characteristics GO:0046546 23 0.067
regulation of proteolysis GO:0030162 293 0.067
pigment biosynthetic process GO:0046148 10 0.066
regulation of vesicle mediated transport GO:0060627 130 0.066
branching morphogenesis of an epithelial tube GO:0048754 19 0.066
positive regulation of peptidyl threonine phosphorylation GO:0010800 9 0.066
regulation of catagen GO:0051794 3 0.066
negative regulation of map kinase activity GO:0043407 27 0.065
positive regulation of myoblast differentiation GO:0045663 6 0.065
homotypic cell cell adhesion GO:0034109 47 0.065
cardiovascular system development GO:0072358 262 0.064
Mouse
regulation of peptidase activity GO:0052547 180 0.064
positive regulation of dna metabolic process GO:0051054 73 0.064
protein processing GO:0016485 226 0.064
cardiac ventricle morphogenesis GO:0003208 20 0.064
regulation of cell morphogenesis GO:0022604 153 0.064
associative learning GO:0008306 1 0.064
organic hydroxy compound metabolic process GO:1901615 147 0.064
negative regulation of protein modification process GO:0031400 200 0.063
regulation of cell adhesion GO:0030155 166 0.063
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.063
cyclic nucleotide metabolic process GO:0009187 82 0.062
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.062
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.062
cell aggregation GO:0098743 1 0.062
regulation of cell matrix adhesion GO:0001952 42 0.062
glycerolipid biosynthetic process GO:0045017 51 0.062
intermediate filament cytoskeleton organization GO:0045104 17 0.062
cytokine production GO:0001816 247 0.061
mucopolysaccharide metabolic process GO:1903510 27 0.061
positive regulation of cytokinesis GO:0032467 29 0.061
peptidyl tyrosine modification GO:0018212 170 0.061
regulation of cellular component biogenesis GO:0044087 281 0.061
tissue morphogenesis GO:0048729 96 0.061
multicellular organismal aging GO:0010259 3 0.061
positive regulation of cell substrate adhesion GO:0010811 37 0.061
muscle organ morphogenesis GO:0048644 19 0.061
sperm motility GO:0030317 6 0.060
regulation of endothelial cell proliferation GO:0001936 56 0.060
regulation of cytoplasmic transport GO:1903649 149 0.059
endodermal cell fate commitment GO:0001711 4 0.059
regulation of smooth muscle cell migration GO:0014910 15 0.059
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.059
cellular response to lipid GO:0071396 127 0.059
cell projection organization GO:0030030 252 0.059
Fly
ion transmembrane transport GO:0034220 338 0.059
glycosyl compound catabolic process GO:1901658 413 0.059
regulation of dna metabolic process GO:0051052 153 0.059
muscle tissue morphogenesis GO:0060415 19 0.059
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.058
long chain fatty acid metabolic process GO:0001676 30 0.058
negative regulation of coagulation GO:0050819 24 0.058
gland development GO:0048732 48 0.058
regulation of response to external stimulus GO:0032101 222 0.058
Mouse
protein localization to membrane GO:0072657 160 0.058
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.057
regulation of phospholipase c activity GO:1900274 14 0.057
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.057
negative regulation of mapk cascade GO:0043409 56 0.057
adherens junction organization GO:0034332 36 0.056
dendritic cell differentiation GO:0097028 13 0.056
positive regulation of chromatin modification GO:1903310 30 0.056
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.056
response to wounding GO:0009611 168 0.056
Mouse
positive regulation of cellular component movement GO:0051272 181 0.055
Mouse
cellular ketone metabolic process GO:0042180 80 0.055
response to hydrogen peroxide GO:0042542 40 0.055
regulation of ras gtpase activity GO:0032318 128 0.055
chordate embryonic development GO:0043009 34 0.054
regulation of defense response GO:0031347 154 0.054
response to radiation GO:0009314 151 0.053
regulation of calcium mediated signaling GO:0050848 17 0.053
peptidyl lysine modification GO:0018205 144 0.053
carbohydrate derivative biosynthetic process GO:1901137 207 0.052
positive regulation of locomotion GO:0040017 186 0.052
Mouse
transposition rna mediated GO:0032197 0 0.052
positive regulation of phospholipase activity GO:0010518 22 0.051
negative regulation of hydrogen peroxide induced cell death GO:1903206 9 0.051
interleukin 1 mediated signaling pathway GO:0070498 12 0.051
natural killer cell activation GO:0030101 12 0.051
vascular endothelial growth factor receptor 1 signaling pathway GO:0036323 1 0.051
regulation of leukocyte differentiation GO:1902105 61 0.050
negative regulation of hair follicle maturation GO:0048817 1 0.050
protein maturation GO:0051604 233 0.050
regulation of protein import into nucleus GO:0042306 78 0.050
response to steroid hormone GO:0048545 80 0.050
jnk cascade GO:0007254 80 0.050
regulation of nucleotide catabolic process GO:0030811 205 0.050
focal adhesion assembly GO:0048041 30 0.050
leukocyte differentiation GO:0002521 98 0.049
regulation of cysteine type endopeptidase activity GO:2000116 127 0.049
endomembrane system organization GO:0010256 196 0.049
regulation of calcium ion transport GO:0051924 79 0.048
vascular wound healing GO:0061042 4 0.048
angiogenesis involved in wound healing GO:0060055 4 0.048
regulation of monophenol monooxygenase activity GO:0032771 1 0.048
negative regulation of cell differentiation GO:0045596 171 0.047
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.047
intermediate filament based process GO:0045103 17 0.047
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.047
protein acylation GO:0043543 138 0.047
positive regulation of developmental process GO:0051094 314 0.047
Worm
regulation of endothelial cell migration GO:0010594 67 0.047
heart development GO:0007507 95 0.046
Mouse
cellular response to lithium ion GO:0071285 2 0.046

PTPRJ disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.277
gastrointestinal system cancer DOID:3119 52 0.268
cancer DOID:162 167 0.268
organ system cancer DOID:0050686 164 0.268
disease of metabolism DOID:0014667 295 0.078
carbohydrate metabolism disease DOID:0050013 32 0.078
acquired metabolic disease DOID:0060158 58 0.078