Homo sapiens

0 known processes

PTTG1

pituitary tumor-transforming 1

(Aliases: MGC126883,MGC138276,TUTR1,PTTG,HPTTG,EAP1)

PTTG1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.849
spindle assembly involved in mitosis GO:0090307 12 0.788
protein k11 linked ubiquitination GO:0070979 24 0.788
cyclin catabolic process GO:0008054 6 0.756
mitotic sister chromatid segregation GO:0000070 53 0.753
meiosis i GO:0007127 4 0.733
Mouse
mitotic nuclear division GO:0007067 119 0.588
organelle fission GO:0048285 149 0.586
Mouse
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.506
spindle organization GO:0007051 53 0.498
positive regulation of chromosome organization GO:2001252 41 0.457
regulation of chromosome segregation GO:0051983 44 0.447
modification dependent macromolecule catabolic process GO:0043632 212 0.423
positive regulation of mitosis GO:0045840 25 0.392
cellular macromolecular complex assembly GO:0034622 324 0.382
mitotic cell cycle GO:0000278 326 0.381
ubiquitin dependent protein catabolic process GO:0006511 206 0.381
spindle stabilization GO:0043146 4 0.371
regulation of mitosis GO:0007088 63 0.357
cellular macromolecule catabolic process GO:0044265 380 0.349
nuclear division GO:0000280 128 0.333
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.297
microtubule based process GO:0007017 210 0.294
sister chromatid segregation GO:0000819 54 0.284
spindle midzone assembly GO:0051255 4 0.273
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.270
deoxyribose phosphate metabolic process GO:0019692 6 0.263
regulation of nuclear division GO:0051783 65 0.254
positive regulation of exit from mitosis GO:0031536 2 0.253
spindle assembly GO:0051225 29 0.252
positive regulation of cellular protein catabolic process GO:1903364 37 0.252
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.250
regulation of cell cycle GO:0051726 393 0.249
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.232
regulation of spindle organization GO:0090224 10 0.220
protein polymerization GO:0051258 71 0.211
regulation of mitotic sister chromatid separation GO:0010965 27 0.198
negative regulation of cellular component organization GO:0051129 235 0.192
histone serine phosphorylation GO:0035404 4 0.190
mitotic cell cycle process GO:1903047 286 0.190
mitotic cytokinesis GO:0000281 19 0.168
regulation of transferase activity GO:0051338 355 0.167
regulation of sister chromatid segregation GO:0033045 27 0.166
positive regulation of cell cycle process GO:0090068 106 0.165
regulation of mitotic cell cycle GO:0007346 189 0.160
dna packaging GO:0006323 77 0.160
microtubule based movement GO:0007018 32 0.159
meiotic chromosome segregation GO:0045132 4 0.155
Mouse
regulation of cell cycle process GO:0010564 266 0.152
modification dependent protein catabolic process GO:0019941 209 0.149
protein ubiquitination GO:0016567 314 0.148
regulation of proteasomal protein catabolic process GO:0061136 87 0.138
determination of adult lifespan GO:0008340 2 0.136
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.136
mitotic sister chromatid separation GO:0051306 18 0.133
metaphase anaphase transition of cell cycle GO:0044784 21 0.133
cellular protein complex assembly GO:0043623 188 0.130
chromosome separation GO:0051304 23 0.129
nucleus localization GO:0051647 1 0.129
negative regulation of cell death GO:0060548 345 0.122
positive regulation of catabolic process GO:0009896 310 0.122
negative regulation of organelle organization GO:0010639 126 0.119
protein k48 linked ubiquitination GO:0070936 38 0.118
single organism cellular localization GO:1902580 332 0.115
proteasomal protein catabolic process GO:0010498 176 0.109
clearance of foreign intracellular dna by conversion of dna cytidine to uridine GO:0044356 1 0.103
microtubule polymerization or depolymerization GO:0031109 37 0.101
negative regulation of chromosome organization GO:2001251 48 0.097
regulation of mitotic cell cycle phase transition GO:1901990 118 0.096
regulation of cell development GO:0060284 161 0.091
spindle assembly checkpoint GO:0071173 17 0.089
regulation of microtubule cytoskeleton organization GO:0070507 61 0.088
positive regulation of cell cycle GO:0045787 140 0.085
2 deoxyribonucleotide metabolic process GO:0009394 6 0.083
dna cytosine deamination GO:0070383 5 0.083
carbohydrate derivative biosynthetic process GO:1901137 207 0.083
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.081
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.081
regulation of protein localization GO:0032880 296 0.081
multi organism cellular process GO:0044764 156 0.078
cellular homeostasis GO:0019725 196 0.078
positive regulation of protein catabolic process GO:0045732 75 0.077
vesicle mediated transport GO:0016192 371 0.076
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.076
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.075
ribonucleoside triphosphate metabolic process GO:0009199 412 0.074
regulation of mitotic sister chromatid segregation GO:0033047 27 0.074
microtubule polymerization GO:0046785 18 0.073
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.073
female gamete generation GO:0007292 2 0.071
protein modification by small protein conjugation GO:0032446 342 0.071
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.070
regulation of chromosome organization GO:0033044 103 0.069
positive regulation of cellular amine metabolic process GO:0033240 7 0.068
protein catabolic process GO:0030163 325 0.066
peptidyl serine phosphorylation GO:0018105 101 0.065
positive regulation of phosphorylation GO:0042327 394 0.065
nucleotide biosynthetic process GO:0009165 109 0.064
peptidyl serine modification GO:0018209 106 0.063
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.063
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.063
negative regulation of protein metabolic process GO:0051248 391 0.062
Mouse
regulation of cell differentiation GO:0045595 393 0.061
cellular protein complex disassembly GO:0043624 36 0.059
purine nucleoside catabolic process GO:0006152 398 0.059
cellular protein catabolic process GO:0044257 261 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.059
cytidine deamination GO:0009972 7 0.055
regulation of cellular protein catabolic process GO:1903362 96 0.055
chromosome segregation GO:0007059 114 0.055
Mouse
tissue regeneration GO:0042246 3 0.054
ribonucleoside catabolic process GO:0042454 406 0.054
viral process GO:0016032 146 0.053
microtubule anchoring GO:0034453 24 0.053
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.053
regulation of cardiac muscle tissue growth GO:0055021 4 0.052
positive regulation of proteolysis GO:0045862 142 0.052
positive regulation of protein phosphorylation GO:0001934 313 0.052
mitotic spindle midzone assembly GO:0051256 4 0.052
regulation of cellular component biogenesis GO:0044087 281 0.048
mitotic spindle organization GO:0007052 27 0.048
organelle assembly GO:0070925 176 0.048
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.048
ribonucleotide catabolic process GO:0009261 405 0.047
cellular amino acid metabolic process GO:0006520 116 0.047
positive regulation of nuclear division GO:0051785 27 0.047
negative regulation of programmed cell death GO:0043069 321 0.045
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.044
reproduction GO:0000003 63 0.043
Mouse
meiotic cell cycle process GO:1903046 8 0.042
Mouse
negative regulation of apoptotic process GO:0043066 316 0.041
positive regulation of transferase activity GO:0051347 227 0.041
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.040
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.040
regulation of proteolysis GO:0030162 293 0.040
Mouse
spindle checkpoint GO:0031577 26 0.040
glycosyl compound catabolic process GO:1901658 413 0.039
maintenance of location in cell GO:0051651 62 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
Mouse
neuromuscular junction development GO:0007528 3 0.038
generation of neurons GO:0048699 152 0.037
positive regulation of transport GO:0051050 336 0.037
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.037
anterior posterior axis specification GO:0009948 2 0.037
blastocyst development GO:0001824 3 0.036
regulation of cell cycle phase transition GO:1901987 126 0.036
positive regulation of protein kinase activity GO:0045860 190 0.036
endocytosis GO:0006897 159 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
cell development GO:0048468 328 0.036
regulation of cell division GO:0051302 116 0.036
cellular amine metabolic process GO:0044106 41 0.035
positive regulation of protein ubiquitination GO:0031398 53 0.035
positive regulation of cell division GO:0051781 59 0.034
establishment of nucleus localization GO:0040023 1 0.034
free ubiquitin chain polymerization GO:0010994 2 0.034
regulation of multi organism process GO:0043900 157 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
regulation of cytoskeleton organization GO:0051493 177 0.033
negative regulation of cellular catabolic process GO:0031330 83 0.033
protein localization to organelle GO:0033365 280 0.033
regulation of ligase activity GO:0051340 29 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
meiotic nuclear division GO:0007126 10 0.033
Mouse
multicellular organismal aging GO:0010259 3 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.032
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.032
mitotic spindle elongation GO:0000022 4 0.032
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.031
mrna metabolic process GO:0016071 175 0.031
cellular ketone metabolic process GO:0042180 80 0.031
regulation of protein catabolic process GO:0042176 155 0.031
positive regulation of organelle organization GO:0010638 195 0.031
negative regulation of protein modification process GO:0031400 200 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
cell cycle phase transition GO:0044770 173 0.030
mitotic cell cycle phase transition GO:0044772 162 0.030
negative regulation of cell cycle process GO:0010948 121 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.029
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.029
regulation of protein ubiquitination GO:0031396 95 0.029
interspecies interaction between organisms GO:0044419 156 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
response to organic cyclic compound GO:0014070 204 0.029
regulation of protein complex assembly GO:0043254 147 0.028
mitotic spindle checkpoint GO:0071174 18 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
negative regulation of proteolysis GO:0045861 132 0.028
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
Mouse
regulation of ubiquitin protein transferase activity GO:0051438 28 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
regulation of viral process GO:0050792 103 0.027
secretion GO:0046903 254 0.027
regulation of protein import into nucleus GO:0042306 78 0.026
chemical homeostasis GO:0048878 306 0.026
regulation of mitotic spindle organization GO:0060236 6 0.026
cellular lipid metabolic process GO:0044255 303 0.026
oogenesis GO:0048477 2 0.025
neuroblast proliferation GO:0007405 4 0.024
negative regulation of protein processing GO:0010955 142 0.024
Mouse
chromatin modification GO:0016568 298 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
dephosphorylation GO:0016311 209 0.024
cell division GO:0051301 168 0.023
cellular chemical homeostasis GO:0055082 180 0.023
negative regulation of sister chromatid segregation GO:0033046 17 0.023
protein processing GO:0016485 226 0.023
Mouse
spindle elongation GO:0051231 4 0.023
regulation of protein maturation GO:1903317 150 0.023
Mouse
reciprocal meiotic recombination GO:0007131 4 0.023
purine containing compound catabolic process GO:0072523 411 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
nuclear migration GO:0007097 1 0.023
negative regulation of phosphorylation GO:0042326 174 0.022
protein localization to kinetochore GO:0034501 10 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
cell morphogenesis GO:0000902 296 0.022
protein targeting to nucleus GO:0044744 104 0.022
maintenance of location GO:0051235 112 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.021
positive regulation of mitotic cell cycle GO:0045931 60 0.021
regulation of kinase activity GO:0043549 314 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
peptidyl threonine modification GO:0018210 45 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
regulation of nucleocytoplasmic transport GO:0046822 98 0.020
nucleoside catabolic process GO:0009164 408 0.020
circulatory system development GO:0072359 262 0.020
neurogenesis GO:0022008 169 0.020
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.020
positive regulation of mitotic metaphase anaphase transition GO:0045842 6 0.019
regulation of cellular component movement GO:0051270 334 0.019
regulation of binding GO:0051098 111 0.019
regulation of intracellular transport GO:0032386 195 0.019
cell projection organization GO:0030030 252 0.019
cell cell signaling GO:0007267 155 0.019
cytidine catabolic process GO:0006216 7 0.019
protein targeting GO:0006605 187 0.019
developmental growth GO:0048589 48 0.018
growth GO:0040007 202 0.018
post embryonic development GO:0009791 2 0.018
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.018
amine metabolic process GO:0009308 44 0.018
establishment of cell polarity GO:0030010 22 0.017
regulation of locomotion GO:0040012 329 0.017
centrosome separation GO:0051299 3 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
deoxyribonucleotide metabolic process GO:0009262 6 0.017
negative regulation of cell cycle GO:0045786 193 0.017
protein depolymerization GO:0051261 30 0.017
oocyte maturation GO:0001556 1 0.017
viral genome replication GO:0019079 50 0.017
secretion by cell GO:0032940 226 0.017
cofactor metabolic process GO:0051186 87 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
clearance of foreign intracellular dna GO:0044355 1 0.016
establishment of spindle localization GO:0051293 12 0.016
viral life cycle GO:0019058 132 0.016
response to lipid GO:0033993 206 0.016
single organism reproductive process GO:0044702 98 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
protein oligomerization GO:0051259 173 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
neuron projection development GO:0031175 106 0.016
regulation of protein polymerization GO:0032271 63 0.016
regulation of cellular response to stress GO:0080135 244 0.015
dna integrity checkpoint GO:0031570 71 0.015
cytokinesis GO:0000910 96 0.015
positive regulation of chromosome segregation GO:0051984 9 0.015
stem cell differentiation GO:0048863 93 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of nervous system development GO:0051960 88 0.015
cytoplasmic transport GO:0016482 379 0.015
cellular response to iron ion GO:0071281 1 0.015
regulation of oocyte development GO:0060281 1 0.014
regulation of meiosis GO:0040020 3 0.014
response to abiotic stimulus GO:0009628 336 0.014
meiotic chromosome separation GO:0051307 3 0.014
nervous system development GO:0007399 293 0.014
regulation of protein transport GO:0051223 213 0.014
response to biotic stimulus GO:0009607 276 0.014
exit from mitosis GO:0010458 10 0.014
regeneration GO:0031099 4 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
mitotic centrosome separation GO:0007100 1 0.013
neuron differentiation GO:0030182 138 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
positive regulation of ligase activity GO:0051351 19 0.013
regulation of homeostatic process GO:0032844 121 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
gonad development GO:0008406 34 0.013
response to oxygen containing compound GO:1901700 369 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
protein autophosphorylation GO:0046777 123 0.013
single fertilization GO:0007338 11 0.013
purine deoxyribonucleoside triphosphate metabolic process GO:0009215 4 0.013
neuron development GO:0048666 113 0.013
mapk cascade GO:0000165 288 0.013
gtp metabolic process GO:0046039 239 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
positive regulation of developmental process GO:0051094 314 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
gtp catabolic process GO:0006184 237 0.012
negative regulation of cytoskeleton organization GO:0051494 45 0.012
positive regulation of protein transport GO:0051222 135 0.012
protein maturation GO:0051604 233 0.012
Mouse
cellular component morphogenesis GO:0032989 314 0.012
embryo development GO:0009790 123 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
Mouse
microtubule depolymerization GO:0007019 18 0.012
regulation of chromatin organization GO:1902275 56 0.012
sex differentiation GO:0007548 45 0.012
immune response GO:0006955 307 0.012
negative regulation of protein maturation GO:1903318 142 0.012
Mouse
intracellular protein transport GO:0006886 270 0.012
microtubule nucleation GO:0007020 6 0.012
muscle contraction GO:0006936 73 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
cell part morphogenesis GO:0032990 137 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of microtubule based process GO:0032886 74 0.011
regulation of viral genome replication GO:0045069 48 0.011
cellular component disassembly GO:0022411 92 0.011
cell projection morphogenesis GO:0048858 129 0.011
nucleoside phosphate catabolic process GO:1901292 412 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
chromatin organization GO:0006325 351 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
oocyte differentiation GO:0009994 2 0.011
response to hormone GO:0009725 175 0.011
negative regulation of developmental process GO:0051093 247 0.011
regulation of neuron projection development GO:0010975 57 0.011
hormone transport GO:0009914 68 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
positive regulation of dna dependent dna replication GO:2000105 7 0.010
coenzyme metabolic process GO:0006732 65 0.010
defense response GO:0006952 315 0.010
protein localization to nucleus GO:0034504 136 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
regulation of neuron differentiation GO:0045664 70 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.010
negative regulation of catabolic process GO:0009895 104 0.010

PTTG1 disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 52 0.032
disease of cellular proliferation DOID:14566 174 0.032
cancer DOID:162 167 0.032
organ system cancer DOID:0050686 164 0.032