Homo sapiens

0 known processes

PUM1

pumilio homolog 1 (Drosophila)

(Aliases: PUML1,HSPUM,KIAA0099,PUMH,PUMH1)

PUM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell development GO:0048468 328 0.884
Fly
stem cell differentiation GO:0048863 93 0.759
negative regulation of developmental process GO:0051093 247 0.675
Worm
cellular component morphogenesis GO:0032989 314 0.569
Fly
circulatory system development GO:0072359 262 0.563
regulation of cell differentiation GO:0045595 393 0.477
stem cell development GO:0048864 69 0.394
nervous system development GO:0007399 293 0.388
Fly
covalent chromatin modification GO:0016569 254 0.377
cell morphogenesis involved in differentiation GO:0000904 144 0.358
Fly
generation of neurons GO:0048699 152 0.345
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.343
neural tube formation GO:0001841 3 0.334
positive regulation of developmental process GO:0051094 314 0.323
segmentation GO:0035282 4 0.309
chromatin modification GO:0016568 298 0.303
neuron differentiation GO:0030182 138 0.294
Fly
cell projection organization GO:0030030 252 0.277
Fly
positive regulation of cell differentiation GO:0045597 211 0.269
cardiovascular system development GO:0072358 262 0.267
heart development GO:0007507 95 0.250
response to external biotic stimulus GO:0043207 261 0.245
enzyme linked receptor protein signaling pathway GO:0007167 303 0.218
Fly
organ morphogenesis GO:0009887 147 0.215
histone lysine methylation GO:0034968 50 0.194
vasculature development GO:0001944 181 0.191
response to biotic stimulus GO:0009607 276 0.188
neuron development GO:0048666 113 0.185
Fly
negative regulation of cell differentiation GO:0045596 171 0.185
stem cell maintenance GO:0019827 19 0.185
female gamete generation GO:0007292 2 0.181
morphogenesis of embryonic epithelium GO:0016331 4 0.181
bmp signaling pathway GO:0030509 49 0.176
regulation of cellular amino acid metabolic process GO:0006521 6 0.176
heart morphogenesis GO:0003007 48 0.174
cell fate determination GO:0001709 3 0.174
response to other organism GO:0051707 261 0.167
oogenesis GO:0048477 2 0.164
neuron projection development GO:0031175 106 0.153
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.150
tube development GO:0035295 125 0.144
posttranscriptional regulation of gene expression GO:0010608 213 0.142
regulation of cell development GO:0060284 161 0.141
histone methylation GO:0016571 60 0.141
embryonic epithelial tube formation GO:0001838 4 0.138
muscle structure development GO:0061061 98 0.133
tube closure GO:0060606 3 0.133
neurogenesis GO:0022008 169 0.132
Fly
cell part morphogenesis GO:0032990 137 0.129
Fly
glial cell migration GO:0008347 4 0.128
mrna metabolic process GO:0016071 175 0.123
memory GO:0007613 3 0.123
Fly
cell projection morphogenesis GO:0048858 129 0.122
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.120
Fly
regulation of nervous system development GO:0051960 88 0.117
Fly
post embryonic development GO:0009791 2 0.117
Worm
head development GO:0060322 108 0.115
blood vessel development GO:0001568 172 0.114
epithelium development GO:0060429 227 0.109
regulation of cell cycle GO:0051726 393 0.106
Worm
neuromuscular junction development GO:0007528 3 0.105
Fly
amine metabolic process GO:0009308 44 0.103
positive regulation of wnt signaling pathway GO:0030177 54 0.101
tissue morphogenesis GO:0048729 96 0.096
epithelial tube morphogenesis GO:0060562 38 0.096
cell morphogenesis GO:0000902 296 0.095
Fly
macromolecule methylation GO:0043414 97 0.095
neuron projection morphogenesis GO:0048812 50 0.093
Fly
regulation of chromatin modification GO:1903308 51 0.092
positive regulation of cellular component organization GO:0051130 376 0.092
regulation of cellular amine metabolic process GO:0033238 11 0.090
positive regulation of organelle organization GO:0010638 195 0.085
negative regulation of cellular protein metabolic process GO:0032269 353 0.084
wnt signaling pathway GO:0016055 156 0.079
primary neural tube formation GO:0014020 3 0.079
central nervous system development GO:0007417 123 0.078
negative regulation of phosphorylation GO:0042326 174 0.076
Worm
chemotaxis GO:0006935 157 0.075
internal protein amino acid acetylation GO:0006475 101 0.074
neuroblast proliferation GO:0007405 4 0.070
histone modification GO:0016570 251 0.070
spermatid differentiation GO:0048515 4 0.070
regulation of ras protein signal transduction GO:0046578 155 0.069
response to oxygen containing compound GO:1901700 369 0.068
Fly
cellular amino acid metabolic process GO:0006520 116 0.065
organelle assembly GO:0070925 176 0.065
protein stabilization GO:0050821 64 0.064
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.063
hemopoiesis GO:0030097 180 0.061
regulation of anatomical structure morphogenesis GO:0022603 286 0.061
cellular amine metabolic process GO:0044106 41 0.061
mitotic cell cycle GO:0000278 326 0.060
apoptotic signaling pathway GO:0097190 268 0.059
regulation of small gtpase mediated signal transduction GO:0051056 156 0.059
mitotic cell cycle phase transition GO:0044772 162 0.059
blood vessel morphogenesis GO:0048514 162 0.058
determination of adult lifespan GO:0008340 2 0.058
ribonucleoprotein complex assembly GO:0022618 78 0.055
regulation of growth GO:0040008 165 0.054
Fly
cellular macromolecular complex assembly GO:0034622 324 0.054
lung cell differentiation GO:0060479 1 0.054
cardiac muscle tissue development GO:0048738 39 0.054
negative regulation of phosphorus metabolic process GO:0010563 267 0.053
Worm
dephosphorylation GO:0016311 209 0.052
lung epithelium development GO:0060428 7 0.052
purine nucleotide catabolic process GO:0006195 405 0.052
negative regulation of multicellular organismal process GO:0051241 317 0.050
Worm
protein ubiquitination GO:0016567 314 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.050
Worm
histone lysine demethylation GO:0070076 14 0.049
embryonic morphogenesis GO:0048598 85 0.049
Fly
proteasomal protein catabolic process GO:0010498 176 0.048
positive regulation of catabolic process GO:0009896 310 0.047
pattern specification process GO:0007389 43 0.047
regulation of purine nucleotide metabolic process GO:1900542 264 0.046
epithelial cell differentiation GO:0030855 141 0.045
ras protein signal transduction GO:0007265 73 0.045
cellular response to dna damage stimulus GO:0006974 379 0.045
negative regulation of cell proliferation GO:0008285 228 0.043
regulation of cellular component size GO:0032535 82 0.042
muscle cell proliferation GO:0033002 35 0.042
positive regulation of cell cycle GO:0045787 140 0.041
regulation of cell morphogenesis GO:0022604 153 0.041
metencephalon development GO:0022037 2 0.041
regulation of protein ubiquitination GO:0031396 95 0.041
neural tube closure GO:0001843 3 0.040
ribonucleoprotein complex biogenesis GO:0022613 116 0.040
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.040
intracellular receptor signaling pathway GO:0030522 104 0.040
regulation of stem cell differentiation GO:2000736 56 0.039
rna processing GO:0006396 255 0.039
hindbrain development GO:0030902 3 0.039
somatic stem cell maintenance GO:0035019 4 0.039
regionalization GO:0003002 29 0.039
neurological system process GO:0050877 163 0.038
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.038
multicellular organismal aging GO:0010259 3 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.037
ribonucleoprotein complex subunit organization GO:0071826 81 0.037
mrna processing GO:0006397 133 0.036
histone demethylation GO:0016577 15 0.035
sensory organ development GO:0007423 52 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
response to fungus GO:0009620 4 0.034
lung development GO:0030324 20 0.034
spermatid development GO:0007286 4 0.034
regulation of multi organism process GO:0043900 157 0.033
membrane organization GO:0061024 292 0.033
negative regulation of catalytic activity GO:0043086 335 0.032
chromatin organization GO:0006325 351 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.032
single organism membrane organization GO:0044802 268 0.032
hair cell differentiation GO:0035315 2 0.032
compound eye development GO:0048749 1 0.031
regulation of intracellular transport GO:0032386 195 0.031
cellular ketone metabolic process GO:0042180 80 0.031
regulation of dephosphorylation GO:0035303 96 0.031
regulation of cell division GO:0051302 116 0.030
Worm
interspecies interaction between organisms GO:0044419 156 0.030
system process GO:0003008 349 0.030
Fly
defense response GO:0006952 315 0.029
negative regulation of protein metabolic process GO:0051248 391 0.029
long term memory GO:0007616 2 0.029
Fly
positive regulation of programmed cell death GO:0043068 249 0.029
cellular response to oxygen containing compound GO:1901701 276 0.028
regulation of cell projection organization GO:0031344 107 0.028
cytoplasmic transport GO:0016482 379 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
response to abiotic stimulus GO:0009628 336 0.028
embryo development GO:0009790 123 0.028
Fly
reproductive process GO:0022414 106 0.027
Worm Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
oocyte development GO:0048599 1 0.027
regulation of cell cycle process GO:0010564 266 0.027
Worm
respiratory tube development GO:0030323 20 0.027
regulation of neuron differentiation GO:0045664 70 0.027
cell cycle phase transition GO:0044770 173 0.027
tube morphogenesis GO:0035239 95 0.026
embryonic organ development GO:0048568 36 0.026
rna catabolic process GO:0006401 71 0.026
regulation of cytoplasmic transport GO:1903649 149 0.026
protein demethylation GO:0006482 17 0.026
protein dealkylation GO:0008214 17 0.026
organophosphate catabolic process GO:0046434 430 0.025
brain development GO:0007420 97 0.025
positive regulation of neurogenesis GO:0050769 49 0.025
epithelial cell development GO:0002064 34 0.025
jak stat cascade GO:0007259 46 0.025
rna splicing GO:0008380 131 0.025
kidney epithelium development GO:0072073 25 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
defense response to other organism GO:0098542 129 0.024
dna repair GO:0006281 198 0.024
viral process GO:0016032 146 0.024
protein alkylation GO:0008213 74 0.024
small gtpase mediated signal transduction GO:0007264 78 0.024
taxis GO:0042330 157 0.024
nitrogen compound transport GO:0071705 191 0.023
response to sterol GO:0036314 14 0.023
negative regulation of organelle organization GO:0010639 126 0.023
mrna catabolic process GO:0006402 56 0.023
demethylation GO:0070988 37 0.023
stem cell division GO:0017145 2 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.023
regulation of protein stability GO:0031647 87 0.022
embryonic eye morphogenesis GO:0048048 2 0.022
blastoderm segmentation GO:0007350 2 0.022
digestive system development GO:0055123 75 0.022
mitotic spindle elongation GO:0000022 4 0.022
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.022
immune response GO:0006955 307 0.022
humoral immune response GO:0006959 49 0.022
multi organism cellular process GO:0044764 156 0.022
striated muscle cell differentiation GO:0051146 43 0.022
positive regulation of cell cycle process GO:0090068 106 0.021
regulation of establishment of protein localization GO:0070201 242 0.021
actin filament based process GO:0030029 224 0.021
aorta morphogenesis GO:0035909 1 0.021
positive regulation of ras gtpase activity GO:0032320 117 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
fat cell differentiation GO:0045444 32 0.021
male meiosis GO:0007140 1 0.021
Worm
biological adhesion GO:0022610 331 0.021
regulation of protein catabolic process GO:0042176 155 0.020
protein localization to organelle GO:0033365 280 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
endomembrane system organization GO:0010256 196 0.020
histone acetylation GO:0016573 93 0.020
positive regulation of ossification GO:0045778 32 0.020
inner ear morphogenesis GO:0042472 4 0.020
nucleobase containing compound transport GO:0015931 51 0.020
response to lipid GO:0033993 206 0.019
behavior GO:0007610 112 0.019
Fly
respiratory system development GO:0060541 22 0.019
regulation of histone modification GO:0031056 47 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
cellular response to organic cyclic compound GO:0071407 127 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
nuclear export GO:0051168 69 0.019
vesicle mediated transport GO:0016192 371 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
regulation of protein complex assembly GO:0043254 147 0.019
regulation of response to dna damage stimulus GO:2001020 94 0.018
striated muscle tissue development GO:0014706 59 0.018
coronary vasculature development GO:0060976 2 0.018
rab protein signal transduction GO:0032482 4 0.018
rna transport GO:0050658 39 0.018
mapk cascade GO:0000165 288 0.018
Worm
regulation of canonical wnt signaling pathway GO:0060828 88 0.018
regulation of mapk cascade GO:0043408 262 0.018
Worm
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
aging GO:0007568 66 0.018
nucleosome organization GO:0034728 66 0.018
morphogenesis of an epithelium GO:0002009 60 0.018
positive regulation of transport GO:0051050 336 0.017
mitotic cell cycle process GO:1903047 286 0.017
protein targeting GO:0006605 187 0.017
single organism cellular localization GO:1902580 332 0.017
response to growth factor GO:0070848 205 0.017
negative regulation of protein modification process GO:0031400 200 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
positive regulation of cell development GO:0010720 92 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
negative regulation of phosphatase activity GO:0010923 61 0.017
circadian behavior GO:0048512 2 0.017
axon development GO:0061564 34 0.017
rna 3 end processing GO:0031123 35 0.017
spindle elongation GO:0051231 4 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
aldehyde biosynthetic process GO:0046184 3 0.016
protein k48 linked ubiquitination GO:0070936 38 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
response to transforming growth factor beta GO:0071559 94 0.016
protein methylation GO:0006479 74 0.016
positive regulation of neuron differentiation GO:0045666 40 0.016
peptidyl lysine modification GO:0018205 144 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
rhythmic behavior GO:0007622 2 0.016
positive regulation of chromatin modification GO:1903310 30 0.016
cardiac chamber development GO:0003205 30 0.016
regulation of response to external stimulus GO:0032101 222 0.016
single organism reproductive process GO:0044702 98 0.016
Worm Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.016
cell cycle g1 s phase transition GO:0044843 80 0.015
cell fate commitment GO:0045165 27 0.015
regulation of anatomical structure size GO:0090066 101 0.015
urogenital system development GO:0001655 65 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
oocyte differentiation GO:0009994 2 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
regulation of chromatin organization GO:1902275 56 0.015
regulation of meiosis GO:0040020 3 0.015
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
protein polyubiquitination GO:0000209 110 0.015
retinal ganglion cell axon guidance GO:0031290 2 0.015
regulation of developmental growth GO:0048638 30 0.015
Fly
positive regulation of nervous system development GO:0051962 54 0.015
gtp metabolic process GO:0046039 239 0.015
positive regulation of cell projection organization GO:0031346 64 0.015
microtubule organizing center organization GO:0031023 62 0.015
developmental process involved in reproduction GO:0003006 66 0.015
Worm
limbic system development GO:0021761 3 0.015
epidermal cell differentiation GO:0009913 45 0.015
protein catabolic process GO:0030163 325 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
eye development GO:0001654 42 0.014
mesonephros development GO:0001823 17 0.014
regulation of protein transport GO:0051223 213 0.014
reproductive structure development GO:0048608 55 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
regulation of kinase activity GO:0043549 314 0.014
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
aorta development GO:0035904 2 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
Fly
cellular protein complex assembly GO:0043623 188 0.014
anterior posterior axis specification GO:0009948 2 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
protein import into nucleus GO:0006606 104 0.014
ameboidal type cell migration GO:0001667 135 0.014
protein localization to nucleus GO:0034504 136 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
Fly
negative regulation of cell cycle GO:0045786 193 0.014
organelle fission GO:0048285 149 0.014
Worm
reproductive system development GO:0061458 56 0.014
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.014
regulation of phosphatase activity GO:0010921 81 0.014
cellular response to lipid GO:0071396 127 0.014
skeletal system development GO:0001501 79 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
positive regulation of growth GO:0045927 58 0.013
engulfment of apoptotic cell GO:0043652 2 0.013
receptor mediated endocytosis GO:0006898 84 0.013
regulation of mrna processing GO:0050684 48 0.013
muscle organ development GO:0007517 56 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
Worm Fly
regulation of dna repair GO:0006282 47 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
growth GO:0040007 202 0.013
Fly
negative regulation of cell death GO:0060548 345 0.013
dendrite development GO:0016358 24 0.013
Fly
molting cycle GO:0042303 28 0.013
microtubule based process GO:0007017 210 0.013
rna splicing via transesterification reactions GO:0000375 90 0.013
peripheral nervous system development GO:0007422 2 0.013
response to cytokine GO:0034097 232 0.013
nucleotide catabolic process GO:0009166 408 0.013
response to radiation GO:0009314 151 0.013
response to hypoxia GO:0001666 96 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
intracellular protein transport GO:0006886 270 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
pericardium development GO:0060039 2 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
nucleus organization GO:0006997 28 0.012
peptidyl lysine methylation GO:0018022 37 0.012
behavioral response to ethanol GO:0048149 2 0.012
Fly
regulation of dendrite morphogenesis GO:0048814 11 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.012
protein acetylation GO:0006473 116 0.012
locomotory behavior GO:0007626 1 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
cell growth GO:0016049 160 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
regulation of nuclear division GO:0051783 65 0.012
Worm
regulation of rab gtpase activity GO:0032313 39 0.012
post embryonic organ development GO:0048569 1 0.012
Worm
regulation of mitosis GO:0007088 63 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
regulation of mrna metabolic process GO:1903311 53 0.012
regulation of heart growth GO:0060420 4 0.012
mesoderm development GO:0007498 14 0.011
pulmonary artery morphogenesis GO:0061156 3 0.011
protein modification by small protein removal GO:0070646 92 0.011
negative regulation of mapk cascade GO:0043409 56 0.011
Worm
regulation of carbohydrate metabolic process GO:0006109 54 0.011
centrosome cycle GO:0007098 32 0.011
negative regulation of dephosphorylation GO:0035305 63 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of rna splicing GO:0043484 62 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
response to hormone GO:0009725 175 0.011
secretion by cell GO:0032940 226 0.011
regulation of translation GO:0006417 89 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
regulation of neurogenesis GO:0050767 82 0.011
protein import GO:0017038 130 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
muscle tissue development GO:0060537 62 0.011
atp catabolic process GO:0006200 157 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
response to decreased oxygen levels GO:0036293 96 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.010
intracellular mrna localization GO:0008298 1 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
dna templated transcription termination GO:0006353 3 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
myosin filament assembly GO:0031034 2 0.010
sensory organ morphogenesis GO:0090596 21 0.010
protein dephosphorylation GO:0006470 81 0.010
protein modification by small protein conjugation GO:0032446 342 0.010

PUM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.035
neurodegenerative disease DOID:1289 102 0.035
nervous system disease DOID:863 431 0.035
sensory system disease DOID:0050155 203 0.028
eye and adnexa disease DOID:1492 150 0.028
eye disease DOID:5614 149 0.022