Homo sapiens

0 known processes

PVRL4

poliovirus receptor-related 4

(Aliases: nectin-4,LNIR,DKFZp686K05193,EDSS1,PRR4)

PVRL4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 6 1.000
natural killer cell mediated immune response to tumor cell GO:0002423 6 1.000
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.989
multi organism membrane fusion GO:0044800 3 0.982
positive regulation of mast cell activation GO:0033005 2 0.966
entry into host GO:0044409 25 0.925
multi organism membrane organization GO:0044803 12 0.918
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.915
membrane fusion involved in viral entry into host cell GO:0039663 3 0.898
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.894
positive regulation of b cell mediated immunity GO:0002714 4 0.883
regulation of immune response to tumor cell GO:0002837 8 0.750
response to tumor cell GO:0002347 10 0.730
movement in host environment GO:0052126 25 0.718
virion attachment to host cell GO:0019062 5 0.711
entry into other organism involved in symbiotic interaction GO:0051828 25 0.634
adhesion of symbiont to host GO:0044406 8 0.577
regulation of mast cell activation GO:0033003 5 0.575
lens morphogenesis in camera type eye GO:0002089 2 0.567
desmosome organization GO:0002934 5 0.508
interspecies interaction between organisms GO:0044419 156 0.475
odontogenesis GO:0042476 25 0.474
cation transport GO:0006812 331 0.470
transition metal ion transport GO:0000041 23 0.435
positive regulation of defense response GO:0031349 87 0.405
entry into host cell GO:0030260 25 0.401
regulation of b cell mediated immunity GO:0002712 7 0.385
viral life cycle GO:0019058 132 0.368
viral process GO:0016032 146 0.321
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.239
viral entry into host cell GO:0046718 24 0.225
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.216
lens development in camera type eye GO:0002088 2 0.208
biomineral tissue development GO:0031214 39 0.207
positive regulation of immune system process GO:0002684 283 0.189
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.187
natural killer cell mediated immunity GO:0002228 23 0.172
response to biotic stimulus GO:0009607 276 0.166
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.164
multi organism cellular process GO:0044764 156 0.164
interaction with host GO:0051701 42 0.139
positive regulation of innate immune response GO:0045089 79 0.135
membrane fusion GO:0061025 43 0.128
cell activation GO:0001775 213 0.125
adaptive immune response GO:0002250 49 0.120
positive regulation of immune response GO:0050778 159 0.119
metal ion transport GO:0030001 272 0.117
small gtpase mediated signal transduction GO:0007264 78 0.116
regulation of immune effector process GO:0002697 91 0.112
immune response to tumor cell GO:0002418 9 0.109
innate immune response GO:0045087 178 0.105
odontogenesis of dentin containing tooth GO:0042475 10 0.105
biological adhesion GO:0022610 331 0.104
regulation of natural killer cell mediated immunity GO:0002715 16 0.103
regulation of cell activation GO:0050865 125 0.101
regulation of defense response GO:0031347 154 0.097
regulation of innate immune response GO:0045088 97 0.096
lymphocyte mediated immunity GO:0002449 48 0.096
regulation of immunoglobulin mediated immune response GO:0002889 7 0.095
regulation of lymphocyte mediated immunity GO:0002706 33 0.087
positive regulation of leukocyte mediated immunity GO:0002705 24 0.084
leukocyte activation GO:0045321 164 0.083
cell adhesion GO:0007155 325 0.081
membrane organization GO:0061024 292 0.081
positive regulation of leukocyte activation GO:0002696 80 0.080
regulation of immune response GO:0050776 201 0.076
tooth mineralization GO:0034505 6 0.076
purine nucleotide catabolic process GO:0006195 405 0.076
natural killer cell mediated cytotoxicity GO:0042267 23 0.076
cell killing GO:0001906 34 0.073
immune response GO:0006955 307 0.071
single organism cell adhesion GO:0098602 179 0.069
single organismal cell cell adhesion GO:0016337 148 0.068
t cell mediated cytotoxicity GO:0001913 9 0.066
regulation of response to biotic stimulus GO:0002831 55 0.066
purine nucleoside triphosphate metabolic process GO:0009144 412 0.066
positive regulation of cell activation GO:0050867 81 0.065
leukocyte mediated cytotoxicity GO:0001909 27 0.064
actin filament based process GO:0030029 224 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.062
fusion of virus membrane with host plasma membrane GO:0019064 3 0.062
regulation of leukocyte mediated immunity GO:0002703 38 0.062
positive regulation of cellular component organization GO:0051130 376 0.062
positive regulation of immune response to tumor cell GO:0002839 8 0.060
epithelial cell differentiation GO:0030855 141 0.058
cell cell junction organization GO:0045216 69 0.058
regulation of nucleoside metabolic process GO:0009118 209 0.057
regulation of cell killing GO:0031341 22 0.057
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.057
regulation of leukocyte activation GO:0002694 115 0.057
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.056
leukocyte mediated immunity GO:0002443 59 0.055
defense response GO:0006952 315 0.054
myeloid leukocyte activation GO:0002274 34 0.054
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.053
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.053
eye morphogenesis GO:0048592 16 0.053
organ morphogenesis GO:0009887 147 0.053
post embryonic development GO:0009791 2 0.052
epidermis morphogenesis GO:0048730 3 0.048
regulation of t cell mediated immunity GO:0002709 18 0.047
positive regulation of immune effector process GO:0002699 40 0.047
positive regulation of nucleotide metabolic process GO:0045981 230 0.046
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.046
cell junction organization GO:0034330 79 0.045
regulation of adaptive immune response GO:0002819 33 0.045
regulation of gtp catabolic process GO:0033124 180 0.044
cellular amine metabolic process GO:0044106 41 0.044
positive regulation of gtpase activity GO:0043547 166 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.043
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
positive regulation of nucleotide catabolic process GO:0030813 185 0.042
regulation of cellular component biogenesis GO:0044087 281 0.042
regulation of small gtpase mediated signal transduction GO:0051056 156 0.040
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.039
determination of adult lifespan GO:0008340 2 0.039
regulation of purine nucleotide catabolic process GO:0033121 205 0.038
multicellular organismal aging GO:0010259 3 0.038
purine ribonucleoside catabolic process GO:0046130 398 0.037
glycosyl compound catabolic process GO:1901658 413 0.036
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 6 0.035
regulation of cell migration GO:0030334 289 0.035
cardiac muscle cell contraction GO:0086003 4 0.034
locomotory behavior GO:0007626 1 0.033
immune effector process GO:0002252 159 0.033
regulation of actin cytoskeleton organization GO:0032956 116 0.033
cellular macromolecular complex assembly GO:0034622 324 0.032
positive regulation of adaptive immune response GO:0002821 21 0.032
regulation of rho protein signal transduction GO:0035023 79 0.032
positive regulation of ras gtpase activity GO:0032320 117 0.032
vesicle mediated transport GO:0016192 371 0.032
gtp metabolic process GO:0046039 239 0.031
mapk cascade GO:0000165 288 0.031
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.030
gtp catabolic process GO:0006184 237 0.030
regulation of protein localization GO:0032880 296 0.030
regulation of actin filament based process GO:0032970 141 0.030
cell projection organization GO:0030030 252 0.029
chemical homeostasis GO:0048878 306 0.029
amine metabolic process GO:0009308 44 0.029
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 6 0.028
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 6 0.028
morphogenesis of embryonic epithelium GO:0016331 4 0.028
oocyte development GO:0048599 1 0.028
cellular response to oxygen containing compound GO:1901701 276 0.028
hair follicle morphogenesis GO:0031069 2 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
oocyte differentiation GO:0009994 2 0.028
cellular component assembly involved in morphogenesis GO:0010927 73 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.027
protein localization to membrane GO:0072657 160 0.027
cell projection assembly GO:0030031 126 0.027
female gamete generation GO:0007292 2 0.026
b cell mediated immunity GO:0019724 10 0.026
iron ion transport GO:0006826 12 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
keratinization GO:0031424 2 0.026
negative regulation of cell proliferation GO:0008285 228 0.025
peripheral nervous system development GO:0007422 2 0.025
positive regulation of cell killing GO:0031343 19 0.025
inner ear morphogenesis GO:0042472 4 0.025
cell cell adhesion GO:0098609 19 0.025
regulation of cell cycle GO:0051726 393 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.024
positive regulation of t cell mediated immunity GO:0002711 12 0.024
single organism cellular localization GO:1902580 332 0.023
susceptibility to natural killer cell mediated cytotoxicity GO:0042271 3 0.023
establishment of protein localization to membrane GO:0090150 121 0.023
negative regulation of cell death GO:0060548 345 0.023
protein maturation GO:0051604 233 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
response to oxygen containing compound GO:1901700 369 0.021
mitotic cell cycle process GO:1903047 286 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
reproductive process GO:0022414 106 0.021
protein processing GO:0016485 226 0.021
regulation of cellular response to stress GO:0080135 244 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
blastoderm segmentation GO:0007350 2 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
positive regulation of organelle organization GO:0010638 195 0.020
dephosphorylation GO:0016311 209 0.020
regulation of transferase activity GO:0051338 355 0.020
retina development in camera type eye GO:0060041 15 0.020
regeneration GO:0031099 4 0.020
negative regulation of developmental process GO:0051093 247 0.020
organelle assembly GO:0070925 176 0.020
segmentation GO:0035282 4 0.020
embryonic epithelial tube formation GO:0001838 4 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
regulation of cell motility GO:2000145 299 0.019
lipid metabolic process GO:0006629 381 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
regulation of cell cycle process GO:0010564 266 0.019
jnk cascade GO:0007254 80 0.019
positive regulation of locomotion GO:0040017 186 0.018
regulation of cell projection organization GO:0031344 107 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
actin filament based movement GO:0030048 17 0.018
regulation of hormone levels GO:0010817 125 0.018
mating GO:0007618 1 0.018
positive regulation of odontogenesis GO:0042482 3 0.018
cellular lipid metabolic process GO:0044255 303 0.018
oogenesis GO:0048477 2 0.018
regulation of stress activated mapk cascade GO:0032872 84 0.018
small molecule biosynthetic process GO:0044283 157 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
sensory organ development GO:0007423 52 0.018
positive regulation of cell death GO:0010942 263 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
regulation of rho gtpase activity GO:0032319 66 0.017
positive regulation of response to biotic stimulus GO:0002833 18 0.017
cellular protein complex assembly GO:0043623 188 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
regulation of proteolysis GO:0030162 293 0.017
maintenance of location GO:0051235 112 0.017
spermatid differentiation GO:0048515 4 0.017
rab protein signal transduction GO:0032482 4 0.017
enamel mineralization GO:0070166 2 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
neuromuscular junction development GO:0007528 3 0.017
compound eye development GO:0048749 1 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
cytoplasmic transport GO:0016482 379 0.016
adult locomotory behavior GO:0008344 1 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
spermatid development GO:0007286 4 0.016
immunoglobulin mediated immune response GO:0016064 10 0.016
epidermal cell differentiation GO:0009913 45 0.016
regulation of viral process GO:0050792 103 0.016
chemotaxis GO:0006935 157 0.016
sensory organ morphogenesis GO:0090596 21 0.016
regulation of testosterone biosynthetic process GO:2000224 2 0.016
transmembrane transport GO:0055085 399 0.016
regulation of kinase activity GO:0043549 314 0.016
response to abiotic stimulus GO:0009628 336 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
pulmonary valve formation GO:0003193 1 0.015
tripartite regional subdivision GO:0007351 2 0.015
regulation of cell cell adhesion GO:0022407 57 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
hindlimb morphogenesis GO:0035137 2 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of cytokine production GO:0001817 232 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
negative regulation of cell cycle GO:0045786 193 0.015
positive regulation of transport GO:0051050 336 0.015
anterior posterior axis specification GO:0009948 2 0.015
regulation of protein processing GO:0070613 150 0.015
memory GO:0007613 3 0.015
actin mediated cell contraction GO:0070252 12 0.014
mitotic cell cycle GO:0000278 326 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
intracellular protein transport GO:0006886 270 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of protein maturation GO:1903317 150 0.014
negative regulation of protein maturation GO:1903318 142 0.014
protein localization to plasma membrane GO:0072659 93 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
cellular protein catabolic process GO:0044257 261 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
positive regulation of tooth mineralization GO:0070172 2 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
response to fungus GO:0009620 4 0.014
sex determination GO:0007530 3 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
regulation of peptidase activity GO:0052547 180 0.014
protein catabolic process GO:0030163 325 0.013
cytokine production GO:0001816 247 0.013
neural tube formation GO:0001841 3 0.013
neurological system process GO:0050877 163 0.013
protein oligomerization GO:0051259 173 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
hormone metabolic process GO:0042445 61 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
cell growth GO:0016049 160 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
oxidation reduction process GO:0055114 396 0.013
protein ubiquitination GO:0016567 314 0.013
chromatin modification GO:0016568 298 0.013
epithelial cell proliferation GO:0050673 128 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
cell division GO:0051301 168 0.013
regulation of cell growth GO:0001558 135 0.013
mitochondrion organization GO:0007005 156 0.013
eye development GO:0001654 42 0.013
nitrogen compound transport GO:0071705 191 0.013
negative regulation of proteolysis GO:0045861 132 0.013
organelle localization GO:0051640 84 0.012
insemination GO:0007320 1 0.012
growth GO:0040007 202 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
positive regulation of t cell mediated cytotoxicity GO:0001916 7 0.012
cell chemotaxis GO:0060326 112 0.012
cell part morphogenesis GO:0032990 137 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
cell fate determination GO:0001709 3 0.012
tissue regeneration GO:0042246 3 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
protein targeting GO:0006605 187 0.012
cardiac muscle contraction GO:0060048 34 0.012
neurogenesis GO:0022008 169 0.012
endocytosis GO:0006897 159 0.012
regulation of protein transport GO:0051223 213 0.012
regulation of jnk cascade GO:0046328 73 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
negative regulation of cell motility GO:2000146 104 0.012
regulation of dephosphorylation GO:0035303 96 0.012
regulation of meiosis GO:0040020 3 0.012
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.012
organ formation GO:0048645 3 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.012
sebaceous gland development GO:0048733 1 0.012
cellular component disassembly GO:0022411 92 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
rhythmic behavior GO:0007622 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
negative regulation of transport GO:0051051 176 0.011
endosomal transport GO:0016197 129 0.011
regulation of angiogenesis GO:0045765 92 0.011
sensory perception of pain GO:0019233 4 0.011
regulation of response to external stimulus GO:0032101 222 0.011
cation homeostasis GO:0055080 189 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
secretory granule organization GO:0033363 2 0.011
regulation of growth GO:0040008 165 0.011
primary neural tube formation GO:0014020 3 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of dermatome development GO:0061183 3 0.011
embryonic forelimb morphogenesis GO:0035115 4 0.011
retinoic acid biosynthetic process GO:0002138 2 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.011
negative regulation of immune system process GO:0002683 136 0.011
vesicle organization GO:0016050 62 0.011
meiotic chromosome segregation GO:0045132 4 0.011
circadian behavior GO:0048512 2 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
cilium organization GO:0044782 68 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
defense response to fungus GO:0050832 4 0.011
glycoprotein metabolic process GO:0009100 110 0.011
rna processing GO:0006396 255 0.011
neural crest cell development GO:0014032 3 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
myosin filament assembly GO:0031034 2 0.011
organic acid biosynthetic process GO:0016053 97 0.011
plasma membrane organization GO:0007009 115 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
protein polymerization GO:0051258 71 0.011
camera type eye morphogenesis GO:0048593 12 0.010
regulation of secretion by cell GO:1903530 177 0.010
protein acylation GO:0043543 138 0.010
atp metabolic process GO:0046034 176 0.010
multi organism reproductive process GO:0044703 54 0.010
covalent chromatin modification GO:0016569 254 0.010
epithelium development GO:0060429 227 0.010
positive regulation of aldosterone metabolic process GO:0032346 2 0.010
regulation of cellular component size GO:0032535 82 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
stem cell division GO:0017145 2 0.010
protein secretion GO:0009306 98 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.010
response to external biotic stimulus GO:0043207 261 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.010
small molecule catabolic process GO:0044282 92 0.010
cellular component morphogenesis GO:0032989 314 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
positive regulation of transferase activity GO:0051347 227 0.010
atrioventricular valve development GO:0003171 3 0.010
nuclear transport GO:0051169 179 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
alcohol metabolic process GO:0006066 114 0.010
activation of immune response GO:0002253 114 0.010
limbic system development GO:0021761 3 0.010
cellular response to acid chemical GO:0071229 44 0.010
positive regulation of developmental process GO:0051094 314 0.010
androgen biosynthetic process GO:0006702 3 0.010

PVRL4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.020
nervous system disease DOID:863 431 0.020
musculoskeletal system disease DOID:17 223 0.016
disease of metabolism DOID:0014667 295 0.015
central nervous system disease DOID:331 186 0.014
auditory system disease DOID:2742 53 0.013
inherited metabolic disorder DOID:655 242 0.013
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
bone disease DOID:0080001 88 0.012
connective tissue disease DOID:65 109 0.012
immune system disease DOID:2914 155 0.011