Homo sapiens

359 known processes

PYCARD

PYD and CARD domain containing

(Aliases: TMS,ASC,TMS-1,TMS1,MGC10332,CARD5)

PYCARD biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
interleukin 1 production GO:0032612 26 0.987
regulation of interleukin 1 beta production GO:0032651 18 0.985
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.965
interleukin 1 beta secretion GO:0050702 15 0.959
regulation of peptidase activity GO:0052547 180 0.949
positive regulation of peptidase activity GO:0010952 88 0.863
regulation of cysteine type endopeptidase activity GO:2000116 127 0.861
interleukin 1 beta production GO:0032611 22 0.858
response to biotic stimulus GO:0009607 276 0.858
positive regulation of proteolysis GO:0045862 142 0.849
positive regulation of endopeptidase activity GO:0010950 84 0.839
detection of muramyl dipeptide GO:0032498 1 0.839
cytokine production GO:0001816 247 0.836
defense response GO:0006952 315 0.829
defense response to bacterium GO:0042742 63 0.828
regulation of proteolysis GO:0030162 293 0.827
inflammatory response GO:0006954 79 0.818
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.802
defense response to other organism GO:0098542 129 0.744
innate immune response GO:0045087 178 0.734
response to bacterium GO:0009617 144 0.721
response to other organism GO:0051707 261 0.721
response to wounding GO:0009611 168 0.669
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.665
interleukin 1 secretion GO:0050701 18 0.645
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.641
response to external biotic stimulus GO:0043207 261 0.625
regulation of defense response GO:0031347 154 0.613
negative regulation of response to wounding GO:1903035 47 0.501
regulation of endopeptidase activity GO:0052548 170 0.498
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.488
regulation of cytokine production GO:0001817 232 0.479
positive regulation of immune response GO:0050778 159 0.466
regulation of interleukin 1 production GO:0032652 21 0.455
protein processing GO:0016485 226 0.450
Mouse
regulation of interleukin 1 beta secretion GO:0050706 12 0.436
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.414
Mouse
detection of stimulus GO:0051606 85 0.402
regulation of inflammatory response GO:0050727 46 0.387
Mouse
zymogen activation GO:0031638 70 0.381
Mouse
immune response GO:0006955 307 0.381
activation of cysteine type endopeptidase activity GO:0097202 57 0.337
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.322
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.271
secretion GO:0046903 254 0.267
positive regulation of defense response GO:0031349 87 0.257
protein maturation GO:0051604 233 0.256
Mouse
regulation of innate immune response GO:0045088 97 0.248
positive regulation of cell death GO:0010942 263 0.242
positive regulation of programmed cell death GO:0043068 249 0.239
positive regulation of apoptotic process GO:0043065 246 0.239
response to lipid GO:0033993 206 0.236
activation of immune response GO:0002253 114 0.223
detection of external biotic stimulus GO:0098581 19 0.220
cytokine mediated signaling pathway GO:0019221 109 0.220
response to oxygen containing compound GO:1901700 369 0.217
negative regulation of defense response GO:0031348 47 0.201
response to organonitrogen compound GO:0010243 156 0.194
negative regulation of protein metabolic process GO:0051248 391 0.193
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.179
cellular component morphogenesis GO:0032989 314 0.175
cytoplasmic transport GO:0016482 379 0.175
cellular macromolecular complex assembly GO:0034622 324 0.174
Mouse
regulation of establishment of protein localization GO:0070201 242 0.173
protein oligomerization GO:0051259 173 0.163
oogenesis GO:0048477 2 0.161
regulation of interleukin 1 secretion GO:0050704 14 0.159
regulation of leukocyte activation GO:0002694 115 0.158
negative regulation of response to external stimulus GO:0032102 83 0.155
detection of biotic stimulus GO:0009595 21 0.149
regulation of response to wounding GO:1903034 101 0.147
Mouse
chemokine production GO:0032602 32 0.144
secretion by cell GO:0032940 226 0.139
cellular protein complex assembly GO:0043623 188 0.138
Mouse
defense response to virus GO:0051607 71 0.137
immune effector process GO:0002252 159 0.136
regulation of actin filament based process GO:0032970 141 0.135
Mouse
positive regulation of interleukin 1 beta production GO:0032731 13 0.134
purine containing compound catabolic process GO:0072523 411 0.127
Mouse
regulation of stress activated mapk cascade GO:0032872 84 0.125
cellular amino acid metabolic process GO:0006520 116 0.118
cytokine secretion GO:0050663 64 0.118
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.114
actin filament organization GO:0007015 128 0.110
Mouse
viral life cycle GO:0019058 132 0.110
positive regulation of cellular component organization GO:0051130 376 0.106
regulation of cellular amine metabolic process GO:0033238 11 0.105
determination of adult lifespan GO:0008340 2 0.104
negative regulation of cytokine production GO:0001818 82 0.100
positive regulation of interleukin 1 production GO:0032732 14 0.100
intracellular protein transport GO:0006886 270 0.098
negative regulation of catalytic activity GO:0043086 335 0.094
detection of bacterium GO:0016045 13 0.093
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.091
Mouse
actin filament based process GO:0030029 224 0.090
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.089
Mouse
protein autophosphorylation GO:0046777 123 0.086
regulation of lymphocyte activation GO:0051249 103 0.084
negative regulation of intracellular signal transduction GO:1902532 183 0.082
nucleoside catabolic process GO:0009164 408 0.082
Mouse
cellular ketone metabolic process GO:0042180 80 0.080
autophagy GO:0006914 88 0.080
Mouse
circadian sleep wake cycle GO:0042745 2 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.078
Mouse
regulation of kinase activity GO:0043549 314 0.078
negative regulation of inflammatory response GO:0050728 22 0.075
negative regulation of interleukin 1 beta production GO:0032691 6 0.075
oxidation reduction process GO:0055114 396 0.073
response to cytokine GO:0034097 232 0.073
ribonucleoside catabolic process GO:0042454 406 0.072
Mouse
positive regulation of immune system process GO:0002684 283 0.072
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.071
regulation of leukocyte proliferation GO:0070663 67 0.071
Mouse
response to uv GO:0009411 73 0.070
amine metabolic process GO:0009308 44 0.070
leukocyte activation GO:0045321 164 0.069
regulation of response to external stimulus GO:0032101 222 0.068
Mouse
cellular amine metabolic process GO:0044106 41 0.068
membrane organization GO:0061024 292 0.067
negative regulation of cellular protein metabolic process GO:0032269 353 0.067
ribonucleoside triphosphate catabolic process GO:0009203 391 0.067
Mouse
gtp catabolic process GO:0006184 237 0.066
Mouse
response to virus GO:0009615 126 0.065
guanosine containing compound catabolic process GO:1901069 239 0.065
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.065
Mouse
regulation of cellular response to stress GO:0080135 244 0.064
morphogenesis of embryonic epithelium GO:0016331 4 0.064
cellular response to cytokine stimulus GO:0071345 181 0.063
regulation of cytoplasmic transport GO:1903649 149 0.062
positive regulation of cytokine production GO:0001819 167 0.062
nuclear transport GO:0051169 179 0.062
anatomical structure formation involved in morphogenesis GO:0048646 284 0.061
positive regulation of cellular catabolic process GO:0031331 284 0.061
positive regulation of humoral immune response GO:0002922 3 0.061
negative regulation of peptidase activity GO:0010466 91 0.059
nervous system development GO:0007399 293 0.059
cell development GO:0048468 328 0.059
protein import GO:0017038 130 0.059
viral process GO:0016032 146 0.058
ras protein signal transduction GO:0007265 73 0.058
protein targeting GO:0006605 187 0.058
post embryonic development GO:0009791 2 0.056
glycosyl compound catabolic process GO:1901658 413 0.056
Mouse
sleep GO:0030431 2 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
activation of innate immune response GO:0002218 55 0.055
positive regulation of phosphorylation GO:0042327 394 0.055
cellular macromolecule catabolic process GO:0044265 380 0.054
negative regulation of protein maturation GO:1903318 142 0.053
positive regulation of ras gtpase activity GO:0032320 117 0.053
detection of peptidoglycan GO:0032499 1 0.052
regulation of tumor necrosis factor production GO:0032680 43 0.052
detection of other organism GO:0098543 13 0.052
circadian sleep wake cycle sleep GO:0050802 2 0.052
cell cycle phase transition GO:0044770 173 0.052
mapk cascade GO:0000165 288 0.051
immune response activating signal transduction GO:0002757 90 0.051
i kappab kinase nf kappab signaling GO:0007249 166 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.050
cell projection organization GO:0030030 252 0.050
response to toxic substance GO:0009636 37 0.049
nucleocytoplasmic transport GO:0006913 176 0.049
rho protein signal transduction GO:0007266 26 0.049
negative regulation of multicellular organismal process GO:0051241 317 0.049
response to molecule of bacterial origin GO:0002237 82 0.048
regulation of secretion by cell GO:1903530 177 0.048
protein homooligomerization GO:0051260 100 0.048
negative regulation of immune system process GO:0002683 136 0.048
apoptotic signaling pathway GO:0097190 268 0.047
positive regulation of lymphocyte activation GO:0051251 73 0.047
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.047
purine ribonucleoside catabolic process GO:0046130 398 0.046
Mouse
regulation of secretion GO:0051046 194 0.046
positive regulation of leukocyte activation GO:0002696 80 0.045
cellular response to oxygen containing compound GO:1901701 276 0.045
gtp metabolic process GO:0046039 239 0.044
Mouse
cellular amide metabolic process GO:0043603 69 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.044
cell morphogenesis involved in differentiation GO:0000904 144 0.043
positive regulation of cellular component biogenesis GO:0044089 158 0.043
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.043
Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.043
negative regulation of cellular amine metabolic process GO:0033239 3 0.042
compound eye development GO:0048749 1 0.042
cell morphogenesis GO:0000902 296 0.042
t cell activation GO:0042110 99 0.042
regulation of immune response GO:0050776 201 0.042
actin polymerization or depolymerization GO:0008154 56 0.042
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.042
positive regulation of organelle organization GO:0010638 195 0.041
rhythmic behavior GO:0007622 2 0.041
organic hydroxy compound metabolic process GO:1901615 147 0.040
lymphocyte activation GO:0046649 133 0.040
negative regulation of protein phosphorylation GO:0001933 140 0.040
negative regulation of phosphorylation GO:0042326 174 0.040
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
response to drug GO:0042493 81 0.039
response to hormone GO:0009725 175 0.039
fatty acid metabolic process GO:0006631 115 0.039
spermatid differentiation GO:0048515 4 0.039
positive regulation of cell activation GO:0050867 81 0.039
regulation of protein complex assembly GO:0043254 147 0.038
Mouse
midgut development GO:0007494 1 0.038
biological adhesion GO:0022610 331 0.038
regulation of intracellular transport GO:0032386 195 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
Mouse
protein localization to membrane GO:0072657 160 0.038
protein secretion GO:0009306 98 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
negative regulation of protein processing GO:0010955 142 0.037
system process GO:0003008 349 0.037
regulation of interleukin 12 production GO:0032655 15 0.037
negative regulation of programmed cell death GO:0043069 321 0.036
single organism membrane organization GO:0044802 268 0.036
cellular response to nitrogen compound GO:1901699 144 0.036
cellular response to abiotic stimulus GO:0071214 117 0.036
monocarboxylic acid metabolic process GO:0032787 185 0.035
actin filament bundle organization GO:0061572 54 0.035
multi organism cellular process GO:0044764 156 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
Mouse
positive regulation of transport GO:0051050 336 0.035
single organism cellular localization GO:1902580 332 0.035
positive regulation of stress activated mapk cascade GO:0032874 60 0.035
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.035
ribonucleotide catabolic process GO:0009261 405 0.034
Mouse
cellular lipid metabolic process GO:0044255 303 0.034
female gamete generation GO:0007292 2 0.034
negative regulation of hydrolase activity GO:0051346 182 0.034
cellular response to nutrient levels GO:0031669 69 0.034
organophosphate catabolic process GO:0046434 430 0.033
Mouse
regulation of chemokine production GO:0032642 31 0.033
small gtpase mediated signal transduction GO:0007264 78 0.033
pyroptosis GO:0070269 1 0.033
regulation of actin cytoskeleton organization GO:0032956 116 0.033
Mouse
cell adhesion GO:0007155 325 0.033
brain development GO:0007420 97 0.033
regulation of cell cycle GO:0051726 393 0.033
maintenance of location GO:0051235 112 0.032
regulation of protein localization GO:0032880 296 0.032
negative regulation of interleukin 1 secretion GO:0050711 4 0.032
neurological system process GO:0050877 163 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
Mouse
hemopoiesis GO:0030097 180 0.032
negative regulation of cell death GO:0060548 345 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
Mouse
regulation of cell differentiation GO:0045595 393 0.032
regulation of cell cycle process GO:0010564 266 0.032
regulation of protein processing GO:0070613 150 0.031
epithelium development GO:0060429 227 0.031
endomembrane system organization GO:0010256 196 0.031
head development GO:0060322 108 0.031
positive regulation of cell proliferation GO:0008284 301 0.031
Mouse
response to nutrient levels GO:0031667 81 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.030
positive regulation of nucleotide catabolic process GO:0030813 185 0.030
negative regulation of protein modification process GO:0031400 200 0.030
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.030
cell cycle checkpoint GO:0000075 117 0.030
developmental programmed cell death GO:0010623 3 0.030
regulation of gtp catabolic process GO:0033124 180 0.030
Mouse
interspecies interaction between organisms GO:0044419 156 0.029
positive regulation of gtpase activity GO:0043547 166 0.029
response to abiotic stimulus GO:0009628 336 0.029
response to radiation GO:0009314 151 0.029
chemical homeostasis GO:0048878 306 0.029
protein catabolic process GO:0030163 325 0.029
cellular response to extracellular stimulus GO:0031668 72 0.029
digestive system development GO:0055123 75 0.029
response to nitrogen compound GO:1901698 184 0.029
tumor necrosis factor production GO:0032640 43 0.028
negative regulation of cell proliferation GO:0008285 228 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
protein localization to organelle GO:0033365 280 0.028
regulation of locomotion GO:0040012 329 0.028
Mouse
regulation of gtpase activity GO:0043087 180 0.028
Mouse
neuron death GO:0070997 65 0.028
cellular response to lipid GO:0071396 127 0.028
positive regulation of jnk cascade GO:0046330 52 0.027
regulation of antimicrobial humoral response GO:0002759 1 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
regulation of cell motility GO:2000145 299 0.027
Mouse
purine nucleotide catabolic process GO:0006195 405 0.027
Mouse
multicellular organismal aging GO:0010259 3 0.027
cellular lipid catabolic process GO:0044242 65 0.027
plasma membrane organization GO:0007009 115 0.027
ion transmembrane transport GO:0034220 338 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.027
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 4 0.027
segmentation GO:0035282 4 0.027
intrinsic apoptotic signaling pathway GO:0097193 127 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
Mouse
anatomical structure homeostasis GO:0060249 100 0.027
cellular response to dna damage stimulus GO:0006974 379 0.026
negative regulation of cell cycle process GO:0010948 121 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.026
regulation of transferase activity GO:0051338 355 0.026
regulation of cellular component movement GO:0051270 334 0.026
Mouse
response to organophosphorus GO:0046683 41 0.026
sulfur compound metabolic process GO:0006790 101 0.026
interleukin 12 production GO:0032615 15 0.026
regeneration GO:0031099 4 0.026
regulation of transporter activity GO:0032409 82 0.026
negative regulation of endopeptidase activity GO:0010951 84 0.026
regulation of mitochondrial membrane potential GO:0051881 23 0.026
mononuclear cell proliferation GO:0032943 71 0.026
Mouse
regulation of protein kinase activity GO:0045859 289 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.025
positive regulation of innate immune response GO:0045089 79 0.025
actin cytoskeleton organization GO:0030036 207 0.025
Mouse
regulation of cell growth GO:0001558 135 0.025
jnk cascade GO:0007254 80 0.025
cellular protein catabolic process GO:0044257 261 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
Mouse
positive regulation of cytoskeleton organization GO:0051495 83 0.025
Mouse
response to mechanical stimulus GO:0009612 51 0.024
regulation of membrane potential GO:0042391 95 0.024
epithelial cell proliferation GO:0050673 128 0.024
defense response to gram negative bacterium GO:0050829 14 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
negative regulation of acute inflammatory response GO:0002674 3 0.024
regulation of defense response to bacterium GO:1900424 2 0.024
immune system development GO:0002520 195 0.024
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.024
positive regulation of catabolic process GO:0009896 310 0.024
neurogenesis GO:0022008 169 0.024
cell part morphogenesis GO:0032990 137 0.024
regulation of dna metabolic process GO:0051052 153 0.024
vesicle mediated transport GO:0016192 371 0.024
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.023
Mouse
negative regulation of chemokine production GO:0032682 9 0.023
lymphocyte homeostasis GO:0002260 4 0.023
positive regulation of protein transport GO:0051222 135 0.023
negative regulation of cell cycle GO:0045786 193 0.023
cell projection assembly GO:0030031 126 0.023
negative regulation of transport GO:0051051 176 0.023
neural tube formation GO:0001841 3 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
Mouse
cellular response to external stimulus GO:0071496 111 0.023
response to extracellular stimulus GO:0009991 85 0.022
nuclear import GO:0051170 106 0.022
cellular homeostasis GO:0019725 196 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
regulation of mapk cascade GO:0043408 262 0.022
protein autoprocessing GO:0016540 4 0.022
protein localization to plasma membrane GO:0072659 93 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
stress activated mapk cascade GO:0051403 93 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
negative regulation of protein transport GO:0051224 75 0.022
positive regulation of mhc class i biosynthetic process GO:0045345 4 0.022
ossification GO:0001503 121 0.022
lymphocyte proliferation GO:0046651 70 0.022
Mouse
regulation of rho gtpase activity GO:0032319 66 0.022
Mouse
positive regulation of response to external stimulus GO:0032103 88 0.021
cation transport GO:0006812 331 0.021
negative regulation of rho gtpase activity GO:0034259 4 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
Mouse
negative regulation of cell cycle phase transition GO:1901988 89 0.021
lipid metabolic process GO:0006629 381 0.021
nitrogen compound transport GO:0071705 191 0.021
response to peptidoglycan GO:0032494 3 0.021
positive regulation of gtp catabolic process GO:0033126 166 0.021
positive regulation of developmental process GO:0051094 314 0.021
neuron differentiation GO:0030182 138 0.021
programmed necrotic cell death GO:0097300 18 0.021
post embryonic organ development GO:0048569 1 0.021
regulation of protein transport GO:0051223 213 0.021
regulation of autophagy GO:0010506 52 0.021
Mouse
negative regulation of proteolysis GO:0045861 132 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
Mouse
peripheral nervous system development GO:0007422 2 0.020
carbohydrate metabolic process GO:0005975 207 0.020
mitotic cell cycle process GO:1903047 286 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
Mouse
cell activation GO:0001775 213 0.020
regulation of small gtpase mediated signal transduction GO:0051056 156 0.020
Mouse
response to salt stress GO:0009651 3 0.020
regulation of cell activation GO:0050865 125 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.020
mhc class i biosynthetic process GO:0045341 4 0.020
positive regulation of antimicrobial humoral response GO:0002760 1 0.020
neuron development GO:0048666 113 0.020
maintenance of location in cell GO:0051651 62 0.020
generation of neurons GO:0048699 152 0.020
positive regulation of rho gtpase activity GO:0032321 56 0.019
actin filament bundle assembly GO:0051017 54 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
Mouse
regulation of actin filament polymerization GO:0030833 50 0.019
Mouse
negative regulation of interleukin 1 production GO:0032692 8 0.019
positive regulation of cytoplasmic transport GO:1903651 82 0.019
cell growth GO:0016049 160 0.019
growth GO:0040007 202 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
regulation of protein localization to nucleus GO:1900180 85 0.019
carboxylic acid catabolic process GO:0046395 71 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
Mouse
tissue homeostasis GO:0001894 63 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
Mouse
transmembrane transport GO:0055085 399 0.018
organic acid catabolic process GO:0016054 71 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
Mouse
cytokine production involved in immune response GO:0002367 27 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 2 0.018
cellular chemical homeostasis GO:0055082 180 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
myeloid leukocyte activation GO:0002274 34 0.018
regulation of myeloid cell differentiation GO:0045637 81 0.018
regulation of multi organism process GO:0043900 157 0.017
Mouse
aging GO:0007568 66 0.017
regulation of protein polymerization GO:0032271 63 0.017
Mouse
regulation of protein secretion GO:0050708 86 0.017
production of molecular mediator of immune response GO:0002440 37 0.017
eye development GO:0001654 42 0.017
positive regulation of transferase activity GO:0051347 227 0.017
regulation of protein maturation GO:1903317 150 0.017
mitochondrion organization GO:0007005 156 0.017
negative regulation of cytoplasmic transport GO:1903650 46 0.017
negative regulation of interleukin 1 beta secretion GO:0050713 2 0.017
microglial cell activation GO:0001774 2 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
regulation of dephosphorylation GO:0035303 96 0.017
divalent inorganic cation transport GO:0072511 158 0.017
response to axon injury GO:0048678 1 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
interleukin 1 alpha secretion GO:0050703 1 0.017
myeloid cell differentiation GO:0030099 117 0.017
limbic system development GO:0021761 3 0.017
sequestering of metal ion GO:0051238 24 0.017
digestive tract development GO:0048565 75 0.016
nucleotide catabolic process GO:0009166 408 0.016
Mouse
mitotic cell cycle checkpoint GO:0007093 68 0.016
negative regulation of cell migration GO:0030336 102 0.016
leukocyte mediated immunity GO:0002443 59 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
macroautophagy GO:0016236 39 0.016
metal ion transport GO:0030001 272 0.016
response to light stimulus GO:0009416 87 0.016
epithelial cell migration GO:0010631 119 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
oocyte differentiation GO:0009994 2 0.016
negative regulation of catabolic process GO:0009895 104 0.016
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 4 0.016
toxin transport GO:1901998 4 0.016
regulation of viral process GO:0050792 103 0.016
cytokine biosynthetic process GO:0042089 37 0.016
t cell homeostasis GO:0043029 3 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
regulation of homeostatic process GO:0032844 121 0.015
blastoderm segmentation GO:0007350 2 0.015
neuron remodeling GO:0016322 2 0.015
metal ion homeostasis GO:0055065 169 0.015
single organism nuclear import GO:1902593 104 0.015
golgi vesicle transport GO:0048193 80 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
Mouse
response to hypoxia GO:0001666 96 0.015
response to fungus GO:0009620 4 0.015
epithelial cell differentiation GO:0030855 141 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
cellular modified amino acid metabolic process GO:0006575 64 0.015
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
b cell homeostasis GO:0001782 1 0.015
cytosolic calcium ion homeostasis GO:0051480 89 0.015
regulation of epithelial cell proliferation GO:0050678 113 0.015
lipid modification GO:0030258 84 0.015
tube morphogenesis GO:0035239 95 0.015
cellular response to tumor necrosis factor GO:0071356 63 0.015
organic acid biosynthetic process GO:0016053 97 0.015
positive regulation of dna metabolic process GO:0051054 73 0.015
regulation of protein catabolic process GO:0042176 155 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
response to tumor necrosis factor GO:0034612 76 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
tissue migration GO:0090130 119 0.014

PYCARD disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.668
hypersensitivity reaction disease DOID:0060056 25 0.207
hypersensitivity reaction type ii disease DOID:417 19 0.047
disease of metabolism DOID:0014667 295 0.035
inherited metabolic disorder DOID:655 242 0.035
musculoskeletal system disease DOID:17 223 0.024
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
connective tissue disease DOID:65 109 0.023
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
organ system cancer DOID:0050686 164 0.018
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014