|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.703
|
|
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.543
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.414
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.291
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.279
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.275
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.268
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.211
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.196
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.189
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.177
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.176
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.175
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.172
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.164
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.160
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.155
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.155
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.153
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.153
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.152
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.152
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.152
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.140
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.139
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.138
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.137
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.125
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.124
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.123
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.121
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.117
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.114
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.113
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.112
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.108
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.105
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.103
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.101
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.099
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.096
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.094
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.091
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.091
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.090
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.086
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.085
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.084
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.083
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.082
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.082
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.081
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.077
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.077
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.076
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.074
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.074
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.074
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.073
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.073
|
Zebrafish |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.073
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.072
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.072
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.072
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.071
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.070
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.070
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.069
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.069
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.067
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.067
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.066
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.065
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.063
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.063
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.062
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.062
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.062
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.061
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.061
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.061
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.060
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.060
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.059
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.059
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.059
|
Human Zebrafish Mouse Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.057
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.057
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.057
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.056
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.056
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.056
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.056
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.055
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.055
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.055
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.052
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.051
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.051
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.051
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.051
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.050
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.050
|
Yeast |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.049
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.049
|
Human Zebrafish Mouse Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.049
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.048
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.048
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.048
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.048
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.048
|
Human |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.047
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.047
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.046
|
Zebrafish |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.046
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.045
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.045
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.045
|
Human Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.045
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.044
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.044
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.043
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.043
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.043
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.043
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.042
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.042
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.042
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.042
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.042
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.042
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.041
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.041
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.041
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.041
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.040
|
Human Fly |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.040
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.040
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.040
|
Yeast Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.039
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.039
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.038
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.038
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.038
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.038
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.038
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.038
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.038
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.037
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.037
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.037
|
Yeast |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.037
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.037
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.036
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.036
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.036
|
Human Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.036
|
Human Fly |
|
|
midbrain development
|
GO:0030901 |
45 |
0.036
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.036
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.036
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.035
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.035
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.035
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.035
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.035
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.035
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.035
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.035
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.035
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.034
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.034
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.034
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.033
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.033
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.033
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.033
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.033
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.033
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.033
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.033
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.033
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.033
|
Yeast |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.032
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.032
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.032
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.032
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.032
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.031
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.031
|
Human Zebrafish Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.031
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.031
|
Zebrafish |
|
|
epithelium development
|
GO:0060429 |
227 |
0.030
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.030
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.030
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.030
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.030
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.030
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.030
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.030
|
Human Yeast Zebrafish Mouse Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.030
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.030
|
|
|
|
system process
|
GO:0003008 |
349 |
0.030
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.030
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.030
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.030
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.029
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.029
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.029
|
Zebrafish Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.029
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.029
|
Zebrafish |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.029
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.029
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.029
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.028
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.028
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.028
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.028
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.028
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.028
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.028
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.028
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.027
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.027
|
Fly |
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.027
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.027
|
|
|
|
sensory perception of temperature stimulus
|
GO:0050951 |
1 |
0.027
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.026
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.026
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.026
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.026
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.026
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.026
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.026
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.026
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.025
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.025
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.025
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.025
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.025
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.025
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.025
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.025
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.025
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.025
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.025
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.024
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.024
|
Human |
|
|
cilium organization
|
GO:0044782 |
68 |
0.024
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.024
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.024
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.024
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.024
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.024
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.024
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.023
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.023
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.023
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.023
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.023
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.023
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.023
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.023
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.023
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.023
|
|
|
|
head development
|
GO:0060322 |
108 |
0.023
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.023
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.022
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.022
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.022
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.022
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.022
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.022
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.022
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.022
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.022
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.022
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.022
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.022
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.022
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.022
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.022
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.022
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.022
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.021
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.021
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.021
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.021
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.021
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.021
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.021
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.021
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.021
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.021
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.021
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.021
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.021
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.021
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.021
|
Yeast |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.021
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.021
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.020
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.020
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.020
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.020
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.020
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.020
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.020
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.020
|
Human Fly |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.020
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.020
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.020
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.020
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.020
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.020
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.020
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.019
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.019
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.019
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.019
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.019
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.019
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.019
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.019
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.019
|
Fly |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.019
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.019
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.019
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.019
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.019
|
Fly |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.019
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.019
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.019
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.018
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.018
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.018
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.018
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.018
|
Human Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.018
|
Human |
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.018
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.018
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.018
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.018
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.018
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.018
|
Fly |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.018
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.018
|
Fly |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.017
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.017
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.017
|
Fly |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.017
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.017
|
Fly |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.017
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.017
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.017
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.017
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.017
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.017
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.017
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.017
|
|
|
|
mating
|
GO:0007618 |
1 |
0.017
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.017
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.017
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.017
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
adaptation of signaling pathway
|
GO:0023058 |
7 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.017
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.017
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.017
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.017
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.017
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.017
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.017
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.017
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.016
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.016
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.016
|
Zebrafish Fly |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.016
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.016
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.016
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.016
|
|
|
|
negative regulation of calcium ion transport into cytosol
|
GO:0010523 |
3 |
0.016
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.016
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.016
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.016
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.016
|
|
|
|
memory
|
GO:0007613 |
3 |
0.016
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.016
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.016
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.016
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.016
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.016
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.016
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.016
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.016
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.016
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.016
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.016
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.016
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.016
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.016
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.016
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.016
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.016
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.016
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.016
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.016
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.016
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.016
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.015
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.015
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.015
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.015
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.015
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.015
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.015
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.015
|
Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.015
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.015
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.015
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.015
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.015
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.015
|
Human |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.015
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.015
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.015
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.015
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.015
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.015
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.015
|
Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.015
|
Human Fly |
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.015
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.015
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
43 |
0.015
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.014
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.014
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.014
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.014
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.014
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.014
|
Human |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.014
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.014
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.014
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.014
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.014
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.014
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.014
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.014
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.014
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.014
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.014
|
Human |
|
|
dna repair
|
GO:0006281 |
198 |
0.014
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.014
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.014
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.014
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.014
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.014
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.014
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.014
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.014
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.014
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.014
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.014
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.014
|
Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.014
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.014
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.014
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.014
|
Human |
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.014
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.014
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.014
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.014
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.014
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.014
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.013
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.013
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.013
|
|
