Homo sapiens

0 known processes

RAD18

RAD18 homolog (S. cerevisiae)

(Aliases: RNF73)

RAD18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 101 0.999
double strand break repair via homologous recombination GO:0000724 50 0.998
protein modification by small protein conjugation GO:0032446 342 0.998
postreplication repair GO:0006301 12 0.998
dna repair GO:0006281 198 0.997
translesion synthesis GO:0019985 8 0.996
recombinational repair GO:0000725 50 0.994
cellular response to dna damage stimulus GO:0006974 379 0.985
Mouse
response to radiation GO:0009314 151 0.981
Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.922
protein ubiquitination GO:0016567 314 0.893
dna biosynthetic process GO:0071897 40 0.874
meiosis i GO:0007127 4 0.859
response to light stimulus GO:0009416 87 0.777
Mouse
dna recombination GO:0006310 77 0.740
Mouse
negative regulation of camp mediated signaling GO:0043951 4 0.717
response to uv GO:0009411 73 0.689
Mouse
protein polyubiquitination GO:0000209 110 0.687
protein monoubiquitination GO:0006513 39 0.678
histone modification GO:0016570 251 0.667
response to abiotic stimulus GO:0009628 336 0.630
Mouse
chromatin modification GO:0016568 298 0.611
organophosphate catabolic process GO:0046434 430 0.584
dna damage checkpoint GO:0000077 68 0.529
glycosyl compound catabolic process GO:1901658 413 0.488
dna integrity checkpoint GO:0031570 71 0.453
ribonucleoside triphosphate metabolic process GO:0009199 412 0.401
response to ionizing radiation GO:0010212 65 0.380
reciprocal meiotic recombination GO:0007131 4 0.373
telomere maintenance via recombination GO:0000722 4 0.371
covalent chromatin modification GO:0016569 254 0.361
regulation of response to dna damage stimulus GO:2001020 94 0.344
protein k11 linked ubiquitination GO:0070979 24 0.326
nucleoside phosphate catabolic process GO:1901292 412 0.322
regulation of protein ubiquitination GO:0031396 95 0.301
cellular macromolecule catabolic process GO:0044265 380 0.282
signal transduction in response to dna damage GO:0042770 57 0.281
negative regulation of cell cycle GO:0045786 193 0.267
purine nucleoside catabolic process GO:0006152 398 0.253
positive regulation of cell proliferation GO:0008284 301 0.247
positive regulation of meiosis i GO:0060903 1 0.236
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.234
histone monoubiquitination GO:0010390 20 0.232
histone ubiquitination GO:0016574 31 0.222
purine nucleoside triphosphate catabolic process GO:0009146 392 0.220
nuclear division GO:0000280 128 0.216
centrosome separation GO:0051299 3 0.215
purine ribonucleoside metabolic process GO:0046128 437 0.211
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.211
regulation of dna metabolic process GO:0051052 153 0.208
Mouse
purine ribonucleoside catabolic process GO:0046130 398 0.207
purine nucleotide catabolic process GO:0006195 405 0.199
nucleoside triphosphate catabolic process GO:0009143 394 0.185
cell cycle checkpoint GO:0000075 117 0.178
nucleoside monophosphate catabolic process GO:0009125 159 0.173
negative regulation of mitotic cell cycle GO:0045930 102 0.169
intrinsic apoptotic signaling pathway GO:0097193 127 0.168
positive regulation of hydrolase activity GO:0051345 331 0.165
regulation of double strand break repair via homologous recombination GO:0010569 11 0.165
ribonucleoside monophosphate metabolic process GO:0009161 187 0.163
telomere maintenance GO:0000723 32 0.153
nucleotide excision repair GO:0006289 31 0.143
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.139
apoptotic signaling pathway GO:0097190 268 0.136
dna replication GO:0006260 116 0.134
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.133
atp catabolic process GO:0006200 157 0.132
cell division GO:0051301 168 0.131
histone h2a ubiquitination GO:0033522 17 0.129
ribonucleoside catabolic process GO:0042454 406 0.128
purine ribonucleotide catabolic process GO:0009154 404 0.127
positive regulation of catabolic process GO:0009896 310 0.125
nucleotide catabolic process GO:0009166 408 0.122
cellular response to ionizing radiation GO:0071479 32 0.118
purine nucleoside monophosphate metabolic process GO:0009126 186 0.111
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.110
modification dependent macromolecule catabolic process GO:0043632 212 0.106
double strand break repair via single strand annealing GO:0045002 4 0.105
purine nucleoside triphosphate metabolic process GO:0009144 412 0.097
cellular response to abiotic stimulus GO:0071214 117 0.093
mitotic cell cycle process GO:1903047 286 0.093
purine containing compound catabolic process GO:0072523 411 0.091
regulation of cell cycle GO:0051726 393 0.086
positive regulation of cellular catabolic process GO:0031331 284 0.085
nucleoside triphosphate metabolic process GO:0009141 422 0.084
post embryonic development GO:0009791 2 0.083
regulation of cellular response to stress GO:0080135 244 0.080
hemopoiesis GO:0030097 180 0.080
determination of adult lifespan GO:0008340 2 0.080
cellular response to organonitrogen compound GO:0071417 124 0.078
microtubule cytoskeleton organization GO:0000226 176 0.077
negative regulation of cell death GO:0060548 345 0.077
dna synthesis involved in dna repair GO:0000731 6 0.075
mitotic cell cycle checkpoint GO:0007093 68 0.075
dna catabolic process GO:0006308 49 0.074
regulation of transferase activity GO:0051338 355 0.074
regulation of meiosis GO:0040020 3 0.071
chromatin organization GO:0006325 351 0.069
response to oxygen containing compound GO:1901700 369 0.069
mitotic cell cycle GO:0000278 326 0.069
endocytic recycling GO:0032456 12 0.068
oogenesis GO:0048477 2 0.065
ribonucleotide catabolic process GO:0009261 405 0.064
negative regulation of histone phosphorylation GO:0033128 2 0.064
meiotic chromosome segregation GO:0045132 4 0.064
positive regulation of programmed cell death GO:0043068 249 0.063
atp metabolic process GO:0046034 176 0.063
anatomical structure homeostasis GO:0060249 100 0.063
protein acetylation GO:0006473 116 0.062
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.062
mitotic dna integrity checkpoint GO:0044774 30 0.061
female gamete generation GO:0007292 2 0.061
regulation of dna repair GO:0006282 47 0.061
regulation of camp mediated signaling GO:0043949 13 0.059
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.055
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.055
protein autoubiquitination GO:0051865 37 0.054
nucleoside monophosphate metabolic process GO:0009123 191 0.054
positive regulation of protein ubiquitination GO:0031398 53 0.054
mitotic recombination GO:0006312 8 0.054
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.053
reproductive process GO:0022414 106 0.052
Mouse
cilium morphogenesis GO:0060271 75 0.051
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.050
regulation of protein stability GO:0031647 87 0.048
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.048
cellular response to radiation GO:0071478 65 0.048
negative regulation of cell cycle phase transition GO:1901988 89 0.047
organelle fission GO:0048285 149 0.047
telomere organization GO:0032200 33 0.046
modification dependent protein catabolic process GO:0019941 209 0.046
regulation of cell cycle process GO:0010564 266 0.045
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.044
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.044
negative regulation of intracellular signal transduction GO:1902532 183 0.044
guanosine containing compound metabolic process GO:1901068 244 0.043
nucleoside catabolic process GO:0009164 408 0.043
vesicle mediated transport GO:0016192 371 0.042
single organism reproductive process GO:0044702 98 0.041
Mouse
negative regulation of cell cycle process GO:0010948 121 0.041
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
histone phosphorylation GO:0016572 16 0.039
ubiquitin dependent protein catabolic process GO:0006511 206 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
regulation of purine nucleotide catabolic process GO:0033121 205 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.037
mitotic g1 dna damage checkpoint GO:0031571 17 0.036
reproduction GO:0000003 63 0.036
Mouse
regulation of cell division GO:0051302 116 0.036
negative regulation of programmed cell death GO:0043069 321 0.036
axoneme assembly GO:0035082 3 0.036
positive regulation of organelle organization GO:0010638 195 0.036
cellular protein catabolic process GO:0044257 261 0.036
organelle assembly GO:0070925 176 0.035
protein acylation GO:0043543 138 0.035
signal transduction by p53 class mediator GO:0072331 72 0.034
immune system development GO:0002520 195 0.034
cellular response to nitrogen compound GO:1901699 144 0.034
dna dependent dna replication GO:0006261 44 0.033
multicellular organismal aging GO:0010259 3 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.033
positive regulation of fibroblast proliferation GO:0048146 21 0.033
membrane organization GO:0061024 292 0.033
cyclic nucleotide mediated signaling GO:0019935 26 0.032
microtubule organizing center organization GO:0031023 62 0.032
regulation of signal transduction by p53 class mediator GO:1901796 26 0.032
chordate embryonic development GO:0043009 34 0.031
response to nitrogen compound GO:1901698 184 0.031
ribonucleoside monophosphate catabolic process GO:0009158 158 0.031
positive regulation of meiotic cell cycle GO:0051446 2 0.031
positive regulation of gtpase activity GO:0043547 166 0.031
positive regulation of cellular component organization GO:0051130 376 0.031
dna catabolic process endonucleolytic GO:0000737 37 0.030
mitotic cell cycle phase transition GO:0044772 162 0.030
positive regulation of nucleoside metabolic process GO:0045979 186 0.030
negative regulation of cell proliferation GO:0008285 228 0.030
hematopoietic or lymphoid organ development GO:0048534 186 0.029
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.029
dna templated transcription termination GO:0006353 3 0.029
multicellular organismal reproductive process GO:0048609 40 0.029
Mouse
gtp catabolic process GO:0006184 237 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
cellular response to cytokine stimulus GO:0071345 181 0.028
positive regulation of apoptotic process GO:0043065 246 0.028
regulation of protein catabolic process GO:0042176 155 0.028
negative regulation of gene expression epigenetic GO:0045814 19 0.028
positive regulation of phosphorylation GO:0042327 394 0.028
regulation of cell cycle g2 m phase transition GO:1902749 22 0.028
system process GO:0003008 349 0.028
regulation of nucleoside metabolic process GO:0009118 209 0.028
cellular response to oxygen containing compound GO:1901701 276 0.028
second messenger mediated signaling GO:0019932 78 0.028
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
positive regulation of transferase activity GO:0051347 227 0.027
positive regulation of reciprocal meiotic recombination GO:0010845 1 0.027
protein catabolic process GO:0030163 325 0.026
response to cytokine GO:0034097 232 0.026
actin filament based process GO:0030029 224 0.026
base excision repair GO:0006284 21 0.026
regulation of apoptotic signaling pathway GO:2001233 175 0.026
response to drug GO:0042493 81 0.026
cell type specific apoptotic process GO:0097285 125 0.026
protein homooligomerization GO:0051260 100 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
g1 s transition of mitotic cell cycle GO:0000082 78 0.025
histone h4 acetylation GO:0043967 47 0.025
g1 dna damage checkpoint GO:0044783 18 0.025
protein stabilization GO:0050821 64 0.024
dna double strand break processing GO:0000729 10 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
protein localization to organelle GO:0033365 280 0.024
regulation of mitotic cell cycle GO:0007346 189 0.023
blastocyst development GO:0001824 3 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
oxidation reduction process GO:0055114 396 0.022
multi organism reproductive process GO:0044703 54 0.022
Mouse
spermatid development GO:0007286 4 0.022
mitotic dna damage checkpoint GO:0044773 28 0.022
histone acetylation GO:0016573 93 0.022
response to inorganic substance GO:0010035 127 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
regulation of kinase activity GO:0043549 314 0.021
chromosome segregation GO:0007059 114 0.021
sensory perception GO:0007600 103 0.021
dna strand elongation involved in dna replication GO:0006271 3 0.021
reciprocal dna recombination GO:0035825 4 0.021
centrosome organization GO:0051297 58 0.021
cell projection organization GO:0030030 252 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
cell development GO:0048468 328 0.020
dna catabolic process exonucleolytic GO:0000738 17 0.020
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
regulation of establishment of protein localization GO:0070201 242 0.019
cell projection assembly GO:0030031 126 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
embryo development GO:0009790 123 0.019
internal protein amino acid acetylation GO:0006475 101 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
leukocyte apoptotic process GO:0071887 31 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
meiotic nuclear division GO:0007126 10 0.018
ras protein signal transduction GO:0007265 73 0.018
regulation of intracellular transport GO:0032386 195 0.018
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.018
regulation of tor signaling GO:0032006 30 0.017
microtubule based process GO:0007017 210 0.017
multicellular organism reproduction GO:0032504 42 0.017
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
positive regulation of cell cycle process GO:0090068 106 0.017
regulation of cell cycle phase transition GO:1901987 126 0.017
positive regulation of kinase activity GO:0033674 204 0.017
protein k63 linked ubiquitination GO:0070534 31 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
gtp metabolic process GO:0046039 239 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
spermatid differentiation GO:0048515 4 0.017
negative regulation of organelle organization GO:0010639 126 0.017
small gtpase mediated signal transduction GO:0007264 78 0.016
cell cycle phase transition GO:0044770 173 0.016
carbohydrate metabolic process GO:0005975 207 0.016
mitochondrion organization GO:0007005 156 0.016
histone threonine phosphorylation GO:0035405 7 0.016
cell cycle g1 s phase transition GO:0044843 80 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.015
positive regulation of transport GO:0051050 336 0.015
positive regulation of cell death GO:0010942 263 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
protein oligomerization GO:0051259 173 0.015
regulation of ras protein signal transduction GO:0046578 155 0.014
g2 m transition of mitotic cell cycle GO:0000086 41 0.014
sister chromatid cohesion GO:0007062 24 0.014
ion homeostasis GO:0050801 230 0.014
positive regulation of cell cycle GO:0045787 140 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
cellular response to oxidative stress GO:0034599 85 0.014
positive regulation of proteolysis GO:0045862 142 0.014
negative regulation of growth GO:0045926 97 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
embryo development ending in birth or egg hatching GO:0009792 34 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.013
regulation of cellular component movement GO:0051270 334 0.013
autophagy GO:0006914 88 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
sensory perception of chemical stimulus GO:0007606 38 0.013
regulation of chromatin organization GO:1902275 56 0.013
epithelium development GO:0060429 227 0.013
oocyte differentiation GO:0009994 2 0.013
endosomal transport GO:0016197 129 0.013
cell cycle arrest GO:0007050 71 0.013
muscle contraction GO:0006936 73 0.013
g2 dna damage checkpoint GO:0031572 26 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
protein k48 linked ubiquitination GO:0070936 38 0.013
negative regulation of response to dna damage stimulus GO:2001021 33 0.013
meiotic cell cycle process GO:1903046 8 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
amide transport GO:0042886 76 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
sensory perception of smell GO:0007608 2 0.012
wnt signaling pathway GO:0016055 156 0.012
t cell activation GO:0042110 99 0.012
regulation of growth GO:0040008 165 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
male meiosis GO:0007140 1 0.012
cellular component morphogenesis GO:0032989 314 0.011
response to acid chemical GO:0001101 66 0.011
secretion GO:0046903 254 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
cell growth GO:0016049 160 0.011
leukocyte mediated immunity GO:0002443 59 0.011
response to organonitrogen compound GO:0010243 156 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
regulation of fibroblast proliferation GO:0048145 32 0.011
regulation of gtpase activity GO:0043087 180 0.011
leukocyte differentiation GO:0002521 98 0.011
negative regulation of dna metabolic process GO:0051053 57 0.010
Mouse
cellular protein complex assembly GO:0043623 188 0.010
cdc42 protein signal transduction GO:0032488 4 0.010
endocytosis GO:0006897 159 0.010
dephosphorylation GO:0016311 209 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
regulation of dna replication GO:0006275 68 0.010
non recombinational repair GO:0000726 14 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
rho protein signal transduction GO:0007266 26 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010

RAD18 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.748
hematopoietic system disease DOID:74 100 0.702
anemia DOID:2355 55 0.388
bone marrow disease DOID:4961 31 0.384
aplastic anemia DOID:12449 30 0.333
disease of cellular proliferation DOID:14566 174 0.268
cancer DOID:162 167 0.186
congenital hypoplastic anemia DOID:1342 26 0.172
organ system cancer DOID:0050686 164 0.164
thoracic cancer DOID:5093 21 0.043
breast cancer DOID:1612 21 0.043
fanconi s anemia DOID:13636 16 0.036
xeroderma pigmentosum DOID:0050427 8 0.016
disease of metabolism DOID:0014667 295 0.013
hematologic cancer DOID:2531 36 0.011
immune system cancer DOID:0060083 36 0.011