|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
1.000
|
Human Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
Worm Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
Worm Fly |
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
1.000
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.999
|
Human |
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.999
|
Fly |
|
|
autophagy
|
GO:0006914 |
88 |
0.999
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.999
|
Human Rat Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.999
|
Human Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.999
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.999
|
Fly |
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.999
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.999
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.998
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.998
|
Fly |
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.998
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.997
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.997
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.997
|
Fly |
|
|
macroautophagy
|
GO:0016236 |
39 |
0.996
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.996
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.996
|
Fly |
|
|
visual learning
|
GO:0008542 |
1 |
0.995
|
|
|
|
negative regulation of response to nutrient levels
|
GO:0032108 |
5 |
0.995
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.995
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.994
|
Fly |
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.994
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.993
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.992
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.992
|
Mouse Fly |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.991
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.991
|
Rat |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.991
|
Rat |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.990
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.990
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.990
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.989
|
Rat |
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.988
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.988
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.988
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.988
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.986
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.986
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.986
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.985
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.984
|
Human Rat Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.981
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.980
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.980
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.979
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.979
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.976
|
Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.976
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.976
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.975
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.974
|
Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.974
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.974
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.973
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.973
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.973
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.972
|
Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.972
|
|
|
|
growth
|
GO:0040007 |
202 |
0.969
|
Fly |
|
|
transposition rna mediated
|
GO:0032197 |
0 |
0.969
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.968
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.968
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.966
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.966
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.963
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.962
|
Mouse Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.961
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.960
|
Fly |
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.960
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.957
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.957
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.955
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.955
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.954
|
Rat |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.949
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.946
|
Human Rat Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.942
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.942
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.941
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.940
|
|
|
|
peroxisome degradation
|
GO:0030242 |
1 |
0.940
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.939
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.936
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.934
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.934
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.932
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.931
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.930
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.930
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.929
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.928
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.928
|
Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.922
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.922
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.920
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.919
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.917
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.917
|
Human Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.916
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.914
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.912
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.909
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.907
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.905
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
3 |
0.902
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.901
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.901
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.900
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.898
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.897
|
|
|
|
vasoconstriction
|
GO:0042310 |
11 |
0.896
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.895
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.894
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.892
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.892
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.892
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.891
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.891
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.890
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.890
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.888
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.888
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.887
|
Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.886
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.886
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.885
|
Rat |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
12 |
0.884
|
Fly |
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.884
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.880
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.879
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.879
|
Worm |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.879
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.874
|
Mouse Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.872
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.872
|
Fly |
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.869
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.868
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.866
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.865
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.864
|
Rat |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.862
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.862
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.861
|
Worm Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.860
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.854
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.852
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.852
|
Rat |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.851
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.846
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.842
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.841
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.832
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.832
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.832
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.831
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.831
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.830
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.829
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.829
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.828
|
Fly |
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.827
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.822
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.821
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.818
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.817
|
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.813
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.812
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.803
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.798
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.798
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.795
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.794
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.791
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.790
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.785
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.783
|
Rat |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.782
|
Mouse Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.780
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.780
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.778
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.777
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.777
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.776
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.775
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.775
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.766
|
Mouse |
|
|
vasculature development
|
GO:0001944 |
181 |
0.763
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.762
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.759
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.758
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.752
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.750
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.750
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.749
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.745
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.744
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.743
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.743
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.742
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.738
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.735
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.733
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.731
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.731
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.730
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.729
|
Mouse Fly |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.726
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.715
|
Human Rat Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.714
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.709
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.708
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.708
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.705
|
Fly |
|
|
vesicle localization
|
GO:0051648 |
26 |
0.703
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.699
|
Worm |
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.696
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.696
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.691
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.685
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.683
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.671
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.669
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.667
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.660
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.659
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.650
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.648
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.637
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.636
|
Fly |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.636
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.633
|
Mouse Fly |
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.630
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.628
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.626
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.626
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.622
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.619
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.617
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.616
|
|
|
|
memory
|
GO:0007613 |
3 |
0.611
|
|
|
|
system process
|
GO:0003008 |
349 |
0.610
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.609
|
Fly |
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.609
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.605
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.599
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.596
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.591
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.590
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.589
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.588
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.587
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.585
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.584
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.579
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.572
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.567
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.564
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.561
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.549
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.544
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.544
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.535
|
|
|
|
positive regulation of glucosylceramide catabolic process
|
GO:2000753 |
1 |
0.535
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.535
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.526
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.523
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.519
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.513
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.512
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.504
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.503
|
|
|
|
positive regulation of glycogen biosynthetic process
|
GO:0045725 |
10 |
0.499
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.493
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.492
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.490
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.485
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.482
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.479
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.470
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.470
|
Mouse Fly |
|
|
neuron development
|
GO:0048666 |
113 |
0.469
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.467
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.467
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.464
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.463
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.461
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.459
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.457
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.453
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.451
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.450
|
Rat |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.449
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.442
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.440
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.437
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.435
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.428
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.427
|
Human |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.424
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.422
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.419
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.414
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.412
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.412
|
Fly |
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.403
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.402
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.402
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.401
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.398
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.392
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.391
|
Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.391
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.390
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.389
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.389
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.388
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.387
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.385
|
Rat |
|
|
epidermis development
|
GO:0008544 |
59 |
0.384
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.381
|
|
|
|
regulation of vasoconstriction
|
GO:0019229 |
5 |
0.380
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.380
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.379
|
|
|
|
vascular smooth muscle contraction
|
GO:0014829 |
5 |
0.375
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.374
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.374
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.373
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.372
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.370
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.366
|
|
|
|
aging
|
GO:0007568 |
66 |
0.366
|
Worm |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.366
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.365
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.364
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.364
|
Human |
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.361
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.349
|
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
4 |
0.346
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.344
|
|
|
|
regulation of rap gtpase activity
|
GO:0032317 |
8 |
0.342
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.339
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.339
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.339
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.336
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.334
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.332
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.332
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.329
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.327
|
|
|
|
fatty acid catabolic process
|
GO:0009062 |
29 |
0.326
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.325
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.325
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.325
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.324
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.323
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.321
|
|
|
|
pigment granule localization
|
GO:0051875 |
7 |
0.318
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.315
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.314
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.314
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.311
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
6 |
0.311
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.308
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.308
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.306
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.305
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.303
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.303
|
Fly |
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.301
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.301
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.301
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.300
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.297
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.292
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.291
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.291
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.289
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.287
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.282
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.281
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.278
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.274
|
|
|
|
positive regulation of vasculogenesis
|
GO:2001214 |
1 |
0.273
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.270
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
16 |
0.269
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.268
|
|
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
22 |
0.266
|
Fly |
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.264
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.264
|
Rat |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.263
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.263
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.262
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.262
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.262
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.261
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.261
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.259
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.258
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.257
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.253
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.253
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.252
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.252
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.251
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.250
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.248
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.245
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.244
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.244
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.243
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.243
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.239
|
Mouse |
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
0.239
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.239
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.239
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.238
|
Fly |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.238
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.238
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.238
|
|
|
|
positive regulation of fatty acid beta oxidation
|
GO:0032000 |
5 |
0.237
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.237
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.237
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.233
|
|
|
|
regulation of glucosylceramide catabolic process
|
GO:2000752 |
1 |
0.232
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.230
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.230
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.230
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.229
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.225
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.222
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.221
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.220
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.219
|
Rat |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.219
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.218
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.217
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.217
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.216
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.214
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.212
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.211
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.210
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.209
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.207
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.206
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.205
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.204
|
Human |
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.200
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.200
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.198
|
Fly |
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.196
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.196
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.194
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.194
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.194
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.192
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.189
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.189
|
Human |
|
|
spindle assembly
|
GO:0051225 |
29 |
0.189
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.187
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.186
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.186
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.181
|
|
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.181
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.178
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.177
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.177
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.177
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.176
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.175
|
|
|
|
mapk import into nucleus
|
GO:0000189 |
1 |
0.174
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.172
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.171
|
Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.170
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.168
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.168
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.167
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.164
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.164
|
Worm Fly |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.163
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.163
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.162
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.161
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.158
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.155
|
Human |
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.155
|
|
