|
|
female gamete generation
|
GO:0007292 |
2 |
0.839
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.815
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.807
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.794
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.789
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.734
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.692
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.679
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.655
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.607
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.577
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.573
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.553
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.539
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.519
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.519
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.499
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.498
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.497
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.492
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.477
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.473
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.461
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.445
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.440
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.438
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.437
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.433
|
Worm |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.431
|
Fly |
|
|
histone methylation
|
GO:0016571 |
60 |
0.430
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.415
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.412
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.406
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.396
|
Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.394
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.392
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.390
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.386
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.383
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.375
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.372
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.359
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.347
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.338
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.336
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.336
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.333
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.330
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.322
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.304
|
Worm |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.299
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.298
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.298
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.296
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.294
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.290
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.285
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.284
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.275
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.275
|
Worm |
|
|
immune response
|
GO:0006955 |
307 |
0.259
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.258
|
Worm |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.257
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.256
|
Worm |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.253
|
Fly |
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.252
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.252
|
Worm |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.251
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.251
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.249
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.243
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.238
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.234
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.232
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.232
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.231
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.230
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.228
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.226
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.226
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.218
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.217
|
Mouse |
|
|
protein methylation
|
GO:0006479 |
74 |
0.215
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.215
|
Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.214
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.214
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.211
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.206
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.206
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.204
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.200
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.196
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.194
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.191
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.190
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.189
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.189
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.188
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.187
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.184
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.184
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.184
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.180
|
Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.178
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.177
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.177
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.175
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.170
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.170
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.170
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.167
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.166
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.165
|
Worm |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.165
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.161
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.159
|
Fly |
|
|
sex differentiation
|
GO:0007548 |
45 |
0.157
|
Worm |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.157
|
Worm |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.157
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.156
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
2 |
0.156
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.155
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.155
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.153
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.153
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.151
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.143
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.141
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.138
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.136
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.133
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.132
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.131
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.130
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.129
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.126
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.126
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.125
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.123
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.122
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.121
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.120
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.119
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.119
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.115
|
Mouse |
|
|
behavior
|
GO:0007610 |
112 |
0.114
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.113
|
Worm |
|
|
defense response
|
GO:0006952 |
315 |
0.112
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.112
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.112
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.112
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.111
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.109
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.109
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.108
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.106
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.105
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.103
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.103
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.101
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.100
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.100
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.099
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.099
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.099
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.097
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.097
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.096
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.095
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.095
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.094
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.094
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.092
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.090
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.090
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.090
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.089
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.089
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.089
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.087
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.087
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.087
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.087
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.086
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.085
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.084
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.083
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.083
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.083
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.082
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.081
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.081
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.080
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.080
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.079
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.079
|
Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.079
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.079
|
Worm |
|
|
system process
|
GO:0003008 |
349 |
0.078
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.078
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.078
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.077
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.076
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.076
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.076
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.075
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.074
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.074
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.072
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.072
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.071
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.071
|
|
|
|
protein desumoylation
|
GO:0016926 |
4 |
0.071
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.071
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.070
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.070
|
Worm |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.070
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.070
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.069
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.069
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.068
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.068
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.068
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.067
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.067
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.066
|
Worm |
|
|
growth
|
GO:0040007 |
202 |
0.066
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.066
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.065
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.065
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.065
|
Mouse |
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.065
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.063
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.063
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.063
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.061
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.061
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.060
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.060
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.060
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.059
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.059
|
Fly |
|
|
protein alkylation
|
GO:0008213 |
74 |
0.058
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.058
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.058
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.057
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.057
|
Worm |
|
|
protein import
|
GO:0017038 |
130 |
0.057
|
Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.057
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.056
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.056
|
Worm |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.055
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.055
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.054
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.053
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.052
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.052
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.052
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.051
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.051
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.051
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.051
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.051
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.050
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.050
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.050
|
Worm |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.049
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.049
|
Mouse |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.049
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.049
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.048
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.048
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.048
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.047
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.047
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.047
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.047
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.047
|
Worm |
|
|
neurological system process
|
GO:0050877 |
163 |
0.047
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.046
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.046
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.045
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.045
|
Worm |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.045
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.045
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.045
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.044
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.044
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.044
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.044
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.044
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.043
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.043
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.043
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.042
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.041
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.041
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.041
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.041
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.040
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.040
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.040
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.040
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.040
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.039
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.039
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.039
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.038
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.038
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.038
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.038
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.038
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.037
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.037
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.037
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.036
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.036
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.036
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.036
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.035
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.035
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.035
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.035
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.034
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.034
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.034
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.034
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.034
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.034
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.034
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.034
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.034
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.033
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.033
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.033
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.032
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.032
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.032
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.032
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.032
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.032
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.032
|
|
|
|
nls bearing protein import into nucleus
|
GO:0006607 |
2 |
0.032
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.032
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.031
|
|
|
|
peptidyl lysine trimethylation
|
GO:0018023 |
10 |
0.031
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.030
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.030
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.030
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.030
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.030
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.029
|
|
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.029
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.029
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.029
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.029
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.029
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.029
|
Mouse |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.028
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.028
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.028
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.028
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.028
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.027
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.027
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.027
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.027
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.027
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.027
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.027
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.027
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.027
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.027
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.027
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.027
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.027
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.026
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.026
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.026
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.026
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.026
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.026
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.026
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.026
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.025
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.025
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.025
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.025
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.025
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.025
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.025
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.025
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.025
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.025
|
|
|
|
microtubule depolymerization
|
GO:0007019 |
18 |
0.025
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.025
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.024
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.024
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.024
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.024
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.024
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.024
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.024
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.023
|
|
|
|
aging
|
GO:0007568 |
66 |
0.023
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.023
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.023
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.023
|
Mouse |
|
|
dna replication
|
GO:0006260 |
116 |
0.023
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.023
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.023
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.023
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.023
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.023
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.022
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.022
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.022
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.022
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.022
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.022
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.022
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.022
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.022
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.022
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
Mouse |
|
|
neuron migration
|
GO:0001764 |
11 |
0.021
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.020
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.020
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.020
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.020
|
|
|
|
histone h2b ubiquitination
|
GO:0033523 |
8 |
0.020
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.020
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.020
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.020
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.020
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.020
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.020
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.020
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.020
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.020
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.020
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.019
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.019
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.019
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.019
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.019
|
|
|
|
modulation by host of viral process
|
GO:0044788 |
3 |
0.019
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.019
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.019
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.019
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.019
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.019
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.019
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.019
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.018
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.018
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.018
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.018
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.018
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.018
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.018
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.018
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.018
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.018
|
Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.018
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.017
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.017
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.017
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.017
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.017
|
|
|
|
memory
|
GO:0007613 |
3 |
0.017
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.017
|
Worm |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.017
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.017
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.017
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.016
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.016
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.016
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.016
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.016
|
|
