|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.860
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.829
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.783
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.643
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.617
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.570
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.562
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.548
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.547
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.545
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.536
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.531
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.473
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.460
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.423
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.406
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.378
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.347
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.346
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.342
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.337
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.330
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.325
|
Human Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.324
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.323
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.317
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.307
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.300
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.288
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.282
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.272
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.269
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.265
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.256
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.247
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.244
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.228
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.225
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.221
|
Mouse |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.217
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.210
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.190
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.181
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.181
|
Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.178
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.175
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.175
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.174
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.167
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.166
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.165
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.163
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.161
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.161
|
Human Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.158
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.154
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.154
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.153
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.143
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.142
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.135
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.128
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.127
|
Human Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.127
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.125
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.123
|
Human Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.123
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.120
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.118
|
Human Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.117
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.116
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.116
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.114
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.111
|
Human Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.111
|
Human Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.110
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.110
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.108
|
Human |
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.104
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.102
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.102
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.101
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.101
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.098
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.097
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.096
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.093
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.091
|
Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.091
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.091
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.089
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.088
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.088
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.084
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.083
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.082
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.079
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.079
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.078
|
Human Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.077
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.076
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.075
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.073
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.072
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.072
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.071
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.071
|
Mouse |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.071
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.070
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.069
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.069
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.068
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.068
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.067
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.066
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.065
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.064
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.064
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.063
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.063
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.061
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.061
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.061
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.060
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.060
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.059
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.059
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.058
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.058
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.057
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.056
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.056
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.054
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.053
|
Human |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.053
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.053
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.053
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.052
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.052
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.052
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.051
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.051
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.051
|
Mouse |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.050
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.050
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.050
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.050
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.049
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.049
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.049
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.049
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.048
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.048
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.047
|
Fly |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.047
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.047
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.046
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.046
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.046
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.045
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.044
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.044
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.044
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.043
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.043
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.043
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.042
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.042
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.042
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.041
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.041
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.041
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.041
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.041
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.041
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.040
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.040
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.040
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.040
|
Human Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.040
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.039
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.038
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.038
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.038
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.038
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.038
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.038
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.038
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.037
|
Zebrafish |
|
|
organelle localization
|
GO:0051640 |
84 |
0.037
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.037
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.037
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.037
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.037
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.037
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.036
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.036
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.036
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.036
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.036
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.036
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.036
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.036
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.035
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.035
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.035
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.035
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.035
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.035
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.035
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.034
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.034
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.034
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.034
|
Zebrafish |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.034
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.034
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.034
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.033
|
Human |
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.033
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.033
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.033
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.033
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.033
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.032
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.032
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.032
|
Human Mouse |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.032
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.032
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.032
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.032
|
Zebrafish |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.032
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.032
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.031
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.031
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.031
|
|
|
|
system process
|
GO:0003008 |
349 |
0.031
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.031
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.031
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.031
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.030
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.030
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.030
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.030
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.030
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.030
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.030
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.030
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.030
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.030
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.030
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.030
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.029
|
Human Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.029
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.029
|
|
|
|
neutrophil clearance
|
GO:0097350 |
1 |
0.029
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.029
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.028
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.028
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.028
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.028
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.028
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.028
|
Mouse |
|
|
vesicle organization
|
GO:0016050 |
62 |
0.028
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.027
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.027
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.027
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.027
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.027
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.027
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.026
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.026
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.026
|
Human |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.026
|
Zebrafish |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.026
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.026
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.026
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.026
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.026
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.026
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.025
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.025
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.025
|
|
|
|
growth
|
GO:0040007 |
202 |
0.025
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.025
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.025
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.025
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.025
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.025
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.024
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.024
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.024
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.024
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.024
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.024
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.024
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.024
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.023
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.023
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.023
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.022
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.022
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.022
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.022
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.022
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.022
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.022
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.022
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.022
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.022
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.022
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.022
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.022
|
Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.022
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.021
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.021
|
Fly |
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.021
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.021
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.021
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.021
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.021
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.021
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.021
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.021
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.021
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.021
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.021
|
Worm |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.020
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.020
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.020
|
Human |
|
|
reproduction
|
GO:0000003 |
63 |
0.020
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.020
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.020
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
Fly |
|
|
signal release
|
GO:0023061 |
70 |
0.020
|
Mouse |
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.020
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.019
|
Zebrafish Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.019
|
Zebrafish |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.019
|
Human Mouse |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.019
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.019
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.019
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.019
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.018
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.018
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.018
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.018
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.018
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.018
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.018
|
Human Fly |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.018
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.018
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.018
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.018
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.018
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.018
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.018
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.018
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.017
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.017
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.017
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.017
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.017
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.017
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.017
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.017
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.017
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.017
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.017
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.017
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.017
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.017
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.017
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.017
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.017
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.017
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.017
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.016
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.016
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.016
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.016
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.016
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.016
|
|
|
|
actin filament reorganization
|
GO:0090527 |
1 |
0.016
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.016
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.016
|
Human |
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.016
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.016
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.016
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.016
|
Mouse |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.016
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.016
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.016
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.016
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.016
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.016
|
|
|
|
head development
|
GO:0060322 |
108 |
0.015
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.015
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.015
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.015
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.015
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.015
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.015
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.015
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.015
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.015
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.015
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.015
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.015
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.015
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.015
|
|
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.014
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.014
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.014
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.014
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.014
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.014
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.014
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.014
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.014
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.014
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.014
|
|
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.014
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.014
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.014
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.014
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.014
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.014
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.014
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.013
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.013
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.013
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.013
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.013
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.013
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.013
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
4 |
0.013
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.013
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.013
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.013
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.013
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.013
|
Human |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.013
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.013
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.013
|
Human |
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.013
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.013
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.013
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.013
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.013
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.013
|
Zebrafish Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.012
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.012
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.012
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.012
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.012
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.012
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.012
|
|
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.012
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.012
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.012
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.012
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.012
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.012
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.012
|
|
|
|
response to parathyroid hormone
|
GO:0071107 |
3 |
0.012
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.012
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.012
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.012
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.012
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.012
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.012
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.012
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.012
|
|
