Homo sapiens

212 known processes

RAPGEF1

Rap guanine nucleotide exchange factor (GEF) 1

(Aliases: C3G,DKFZp781P1719,GRF2)

RAPGEF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 73 0.847
regulation of interleukin 2 secretion GO:1900040 2 0.817
rho protein signal transduction GO:0007266 26 0.780
purine nucleotide catabolic process GO:0006195 405 0.702
regulation of phagocytosis engulfment GO:0060099 2 0.651
small gtpase mediated signal transduction GO:0007264 78 0.611
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.586
nucleoside triphosphate metabolic process GO:0009141 422 0.576
purine containing compound catabolic process GO:0072523 411 0.567
interleukin 2 secretion GO:0070970 3 0.513
ribonucleoside catabolic process GO:0042454 406 0.507
thymus development GO:0048538 3 0.449
glycosyl compound catabolic process GO:1901658 413 0.427
purine nucleoside catabolic process GO:0006152 398 0.426
male genitalia development GO:0030539 1 0.397
guanosine containing compound catabolic process GO:1901069 239 0.396
purine ribonucleoside metabolic process GO:0046128 437 0.363
nucleoside triphosphate catabolic process GO:0009143 394 0.363
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.353
biological adhesion GO:0022610 331 0.348
Mouse
organophosphate catabolic process GO:0046434 430 0.327
regulation of purine nucleotide catabolic process GO:0033121 205 0.327
nucleoside phosphate catabolic process GO:1901292 412 0.321
negative regulation of immune system process GO:0002683 136 0.317
ephrin receptor signaling pathway GO:0048013 15 0.316
neuromuscular process controlling balance GO:0050885 7 0.304
syncytium formation by plasma membrane fusion GO:0000768 2 0.288
immune response GO:0006955 307 0.282
regulation of rho gtpase activity GO:0032319 66 0.269
regulation of small gtpase mediated signal transduction GO:0051056 156 0.268
negative regulation of phagocytosis GO:0050765 4 0.267
regulation of mononuclear cell proliferation GO:0032944 65 0.259
cellular ketone metabolic process GO:0042180 80 0.252
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.252
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.251
engulfment of apoptotic cell GO:0043652 2 0.244
purine nucleoside triphosphate catabolic process GO:0009146 392 0.244
purine ribonucleoside catabolic process GO:0046130 398 0.243
regulation of kinase activity GO:0043549 314 0.238
guanosine containing compound metabolic process GO:1901068 244 0.233
enzyme linked receptor protein signaling pathway GO:0007167 303 0.231
Mouse
establishment of planar polarity GO:0001736 3 0.229
membrane organization GO:0061024 292 0.224
positive regulation of extracellular matrix organization GO:1903055 3 0.222
b cell homeostasis GO:0001782 1 0.218
regulation of non canonical wnt signaling pathway GO:2000050 4 0.206
regulation of ras gtpase activity GO:0032318 128 0.199
negative regulation of phagocytosis engulfment GO:0060101 1 0.194
cell projection organization GO:0030030 252 0.192
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 2 0.188
metal ion transport GO:0030001 272 0.188
cell junction maintenance GO:0034331 4 0.187
response to uv GO:0009411 73 0.182
cell activation GO:0001775 213 0.177
regulation of gtp catabolic process GO:0033124 180 0.175
rac protein signal transduction GO:0016601 12 0.175
rap protein signal transduction GO:0032486 7 0.175
regulation of mapk cascade GO:0043408 262 0.174
Mouse
positive regulation of map kinase activity GO:0043406 80 0.172
nucleoside catabolic process GO:0009164 408 0.169
regulation of cell adhesion GO:0030155 166 0.163
gtp catabolic process GO:0006184 237 0.163
gtp metabolic process GO:0046039 239 0.159
regulation of rho protein signal transduction GO:0035023 79 0.157
cation transport GO:0006812 331 0.156
positive regulation of lipase activity GO:0060193 28 0.155
collateral sprouting GO:0048668 2 0.151
compound eye development GO:0048749 1 0.147
purine ribonucleotide catabolic process GO:0009154 404 0.145
actin filament organization GO:0007015 128 0.139
ribonucleoside triphosphate metabolic process GO:0009199 412 0.135
cellular response to nitrogen compound GO:1901699 144 0.135
positive regulation of jnk cascade GO:0046330 52 0.134
post embryonic development GO:0009791 2 0.131
myeloid leukocyte activation GO:0002274 34 0.128
immune response activating signal transduction GO:0002757 90 0.126
astrocyte differentiation GO:0048708 4 0.126
protein modification by small protein conjugation GO:0032446 342 0.124
regulation of phospholipase c activity GO:1900274 14 0.123
secretion GO:0046903 254 0.123
response to light stimulus GO:0009416 87 0.122
positive regulation of rap gtpase activity GO:0032854 8 0.117
activation of protein kinase activity GO:0032147 90 0.117
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.116
modification dependent macromolecule catabolic process GO:0043632 212 0.116
negative regulation of homeostatic process GO:0032845 59 0.116
regulation of ras protein signal transduction GO:0046578 155 0.116
sequestering of calcium ion GO:0051208 17 0.114
defense response GO:0006952 315 0.112
immune response regulating signaling pathway GO:0002764 97 0.110
purine nucleoside triphosphate metabolic process GO:0009144 412 0.109
establishment of tissue polarity GO:0007164 3 0.106
regulation of map kinase activity GO:0043405 108 0.104
regulation of tor signaling GO:0032006 30 0.103
jnk cascade GO:0007254 80 0.103
positive regulation of immune system process GO:0002684 283 0.102
lymphocyte proliferation GO:0046651 70 0.102
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.102
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.101
regulation of endothelial cell apoptotic process GO:2000351 24 0.100
secretion by cell GO:0032940 226 0.099
lymphocyte homeostasis GO:0002260 4 0.099
regulation of nucleotide metabolic process GO:0006140 269 0.097
programmed cell death in response to reactive oxygen species GO:0097468 4 0.097
apoptotic cell clearance GO:0043277 12 0.097
cytosolic calcium ion homeostasis GO:0051480 89 0.097
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.096
response to radiation GO:0009314 151 0.096
regulation of jnk cascade GO:0046328 73 0.095
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.094
ribonucleotide catabolic process GO:0009261 405 0.094
parathyroid gland development GO:0060017 2 0.094
motor neuron axon guidance GO:0008045 2 0.094
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.092
positive regulation of immune response GO:0050778 159 0.091
embryonic viscerocranium morphogenesis GO:0048703 1 0.091
regulation of establishment of planar polarity GO:0090175 5 0.088
circulatory system development GO:0072359 262 0.085
Mouse
innate immune response GO:0045087 178 0.085
regulation of glucocorticoid secretion GO:2000849 4 0.085
negative regulation of phosphate metabolic process GO:0045936 267 0.084
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.081
cellular response to oxygen containing compound GO:1901701 276 0.080
defense response to fungus GO:0050832 4 0.079
exocytosis GO:0006887 71 0.078
regulation of gtpase activity GO:0043087 180 0.078
regulation of homeostatic process GO:0032844 121 0.078
response to catecholamine GO:0071869 7 0.077
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.076
axis elongation GO:0003401 4 0.074
anatomical structure formation involved in morphogenesis GO:0048646 284 0.074
female gamete generation GO:0007292 2 0.074
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.073
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.072
inflammatory response GO:0006954 79 0.071
regulation of immune response GO:0050776 201 0.071
nucleotide catabolic process GO:0009166 408 0.069
modification dependent protein catabolic process GO:0019941 209 0.069
i kappab kinase nf kappab signaling GO:0007249 166 0.069
mononuclear cell proliferation GO:0032943 71 0.068
negative regulation of multicellular organismal process GO:0051241 317 0.068
cell adhesion GO:0007155 325 0.067
Mouse
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.067
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.066
myoblast fusion GO:0007520 1 0.066
actin cytoskeleton organization GO:0030036 207 0.066
negative regulation of regulated secretory pathway GO:1903306 1 0.065
response to nitrogen compound GO:1901698 184 0.064
positive regulation of vasoconstriction GO:0045907 3 0.063
mitotic cell cycle GO:0000278 326 0.062
regulation of nucleoside metabolic process GO:0009118 209 0.061
endothelial cell apoptotic process GO:0072577 26 0.061
organ morphogenesis GO:0009887 147 0.060
positive regulation of cellular catabolic process GO:0031331 284 0.060
sequestering of metal ion GO:0051238 24 0.060
associative learning GO:0008306 1 0.059
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.058
hormone metabolic process GO:0042445 61 0.058
determination of adult lifespan GO:0008340 2 0.058
positive regulation of transport GO:0051050 336 0.058
phagocytosis engulfment GO:0006911 7 0.057
vesicle mediated transport GO:0016192 371 0.057
cellular macromolecule catabolic process GO:0044265 380 0.057
antigen receptor mediated signaling pathway GO:0050851 38 0.056
positive regulation of fibroblast proliferation GO:0048146 21 0.056
regulation of cell cycle GO:0051726 393 0.055
negative regulation of cell adhesion GO:0007162 64 0.054
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.053
regulation of cytoskeleton organization GO:0051493 177 0.053
cell development GO:0048468 328 0.052
response to biotic stimulus GO:0009607 276 0.051
protein secretion GO:0009306 98 0.050
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.050
stress activated mapk cascade GO:0051403 93 0.050
positive regulation of wnt signaling pathway GO:0030177 54 0.050
positive regulation of blood circulation GO:1903524 12 0.049
single organism reproductive process GO:0044702 98 0.049
humoral immune response GO:0006959 49 0.049
regulation of protein secretion GO:0050708 86 0.049
cell cycle checkpoint GO:0000075 117 0.049
somatic stem cell maintenance GO:0035019 4 0.049
actin filament based process GO:0030029 224 0.048
neurotrophin trk receptor signaling pathway GO:0048011 4 0.048
response to bacterium GO:0009617 144 0.047
positive regulation of actin nucleation GO:0051127 6 0.047
regulation of response to wounding GO:1903034 101 0.047
regulation of growth rate GO:0040009 1 0.047
negative regulation of protein metabolic process GO:0051248 391 0.046
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.046
cellular divalent inorganic cation homeostasis GO:0072503 128 0.046
regulation of oxidative stress induced cell death GO:1903201 24 0.045
wnt signaling pathway GO:0016055 156 0.045
Mouse
regulation of leukocyte proliferation GO:0070663 67 0.045
positive regulation of tor signaling GO:0032008 11 0.045
positive regulation of developmental process GO:0051094 314 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.044
response to external biotic stimulus GO:0043207 261 0.044
positive regulation of nucleoside metabolic process GO:0045979 186 0.044
growth GO:0040007 202 0.044
leukocyte activation involved in immune response GO:0002366 30 0.044
positive regulation of rho gtpase activity GO:0032321 56 0.043
endomembrane system organization GO:0010256 196 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.042
response to fungus GO:0009620 4 0.041
signal transduction in response to dna damage GO:0042770 57 0.041
phosphatidylinositol mediated signaling GO:0048015 55 0.041
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.041
response to other organism GO:0051707 261 0.040
stress activated protein kinase signaling cascade GO:0031098 94 0.040
regulation of actin cytoskeleton organization GO:0032956 116 0.040
cytokine secretion GO:0050663 64 0.040
response to nutrient levels GO:0031667 81 0.040
t cell differentiation in thymus GO:0033077 4 0.040
mapk cascade GO:0000165 288 0.039
Mouse
metal ion homeostasis GO:0055065 169 0.039
regulation of natural killer cell differentiation GO:0032823 2 0.039
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.038
response to tumor necrosis factor GO:0034612 76 0.038
cellular calcium ion homeostasis GO:0006874 117 0.038
regulation of cellular response to stress GO:0080135 244 0.038
multicellular organismal aging GO:0010259 3 0.038
cellular response to organonitrogen compound GO:0071417 124 0.037
coagulation GO:0050817 78 0.037
dna damage checkpoint GO:0000077 68 0.037
immune system development GO:0002520 195 0.036
negative regulation of wound healing GO:0061045 25 0.036
positive regulation of jak stat cascade GO:0046427 35 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
morphogenesis of a polarized epithelium GO:0001738 3 0.036
regulation of protein stability GO:0031647 87 0.035
regulation of protein serine threonine kinase activity GO:0071900 179 0.035
regulation of stress activated mapk cascade GO:0032872 84 0.035
2 oxoglutarate metabolic process GO:0006103 4 0.034
response to organonitrogen compound GO:0010243 156 0.034
regulation of mitotic cell cycle GO:0007346 189 0.034
behavioral response to ethanol GO:0048149 2 0.034
cellular response to dna damage stimulus GO:0006974 379 0.034
keratinization GO:0031424 2 0.034
negative regulation of phospholipase activity GO:0010519 3 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
triglyceride homeostasis GO:0070328 14 0.034
response to molecule of bacterial origin GO:0002237 82 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.033
lipid homeostasis GO:0055088 39 0.032
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.032
regulation of hormone levels GO:0010817 125 0.032
regulation of protein ubiquitination GO:0031396 95 0.032
leukocyte proliferation GO:0070661 74 0.032
cellular response to insulin stimulus GO:0032869 41 0.032
negative regulation of leukocyte degranulation GO:0043301 1 0.031
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.031
generation of neurons GO:0048699 152 0.031
negative regulation of erythrocyte differentiation GO:0045647 3 0.031
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.031
negative regulation of cell cycle process GO:0010948 121 0.031
vascular endothelial growth factor receptor 1 signaling pathway GO:0036323 1 0.031
protein ubiquitination GO:0016567 314 0.031
neuromuscular junction development GO:0007528 3 0.031
embryonic digestive tract morphogenesis GO:0048557 2 0.031
nuclear export GO:0051168 69 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
spermatid development GO:0007286 4 0.030
meiotic chromosome segregation GO:0045132 4 0.030
cytoplasmic transport GO:0016482 379 0.030
lamellipodium organization GO:0097581 30 0.030
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.030
response to lipid GO:0033993 206 0.030
positive regulation of gtpase activity GO:0043547 166 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
positive regulation of gtp catabolic process GO:0033126 166 0.029
positive regulation of rac gtpase activity GO:0032855 31 0.029
positive regulation of stress activated mapk cascade GO:0032874 60 0.029
positive regulation of protein secretion GO:0050714 60 0.029
cellular lipid metabolic process GO:0044255 303 0.028
negative regulation of response to wounding GO:1903035 47 0.028
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.028
regulation of blood vessel size GO:0050880 18 0.028
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.028
regulation of cell cycle g1 s phase transition GO:1902806 42 0.028
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.028
lipid metabolic process GO:0006629 381 0.028
signal transduction involved in regulation of gene expression GO:0023019 1 0.027
positive regulation of cytokine secretion GO:0050715 42 0.027
activation of immune response GO:0002253 114 0.027
regulation of hydrogen peroxide induced cell death GO:1903205 10 0.027
chemical homeostasis GO:0048878 306 0.027
stem cell development GO:0048864 69 0.027
signal transduction by p53 class mediator GO:0072331 72 0.027
cell substrate adhesion GO:0031589 132 0.026
t cell differentiation GO:0030217 29 0.026
interleukin 2 production GO:0032623 20 0.026
negative regulation of developmental process GO:0051093 247 0.026
immune effector process GO:0002252 159 0.026
regulation of protein catabolic process GO:0042176 155 0.026
regulation of defense response GO:0031347 154 0.026
nuclear transport GO:0051169 179 0.025
substrate adhesion dependent cell spreading GO:0034446 41 0.025
neurological system process GO:0050877 163 0.025
monovalent inorganic cation transport GO:0015672 128 0.025
regulation of erk1 and erk2 cascade GO:0070372 99 0.025
Mouse
negative regulation of secretion GO:0051048 58 0.025
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.025
regulation of response to external stimulus GO:0032101 222 0.025
oogenesis GO:0048477 2 0.025
peptidyl tyrosine dephosphorylation GO:0035335 36 0.025
chemokine production GO:0032602 32 0.025
response to abiotic stimulus GO:0009628 336 0.025
negative regulation of programmed cell death GO:0043069 321 0.024
regulation of lymphocyte activation GO:0051249 103 0.024
regulation of t cell proliferation GO:0042129 42 0.024
positive regulation of phospholipase activity GO:0010518 22 0.024
cellular modified amino acid metabolic process GO:0006575 64 0.024
cellular response to hydrogen peroxide GO:0070301 37 0.023
mast cell cytokine production GO:0032762 1 0.023
golgi organization GO:0007030 38 0.023
regulation of protein export from nucleus GO:0046825 15 0.023
regulation of protein localization GO:0032880 296 0.023
negative regulation of secretion by cell GO:1903531 52 0.023
response to insulin GO:0032868 45 0.023
regulation of neuron differentiation GO:0045664 70 0.023
cellular response to acid chemical GO:0071229 44 0.023
protein export from nucleus GO:0006611 29 0.023
regulation of vasodilation GO:0042312 4 0.023
fibroblast proliferation GO:0048144 33 0.023
actin filament based movement GO:0030048 17 0.022
maintenance of location GO:0051235 112 0.022
regulation of antimicrobial humoral response GO:0002759 1 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.022
response to lipopolysaccharide GO:0032496 70 0.022
metencephalon development GO:0022037 2 0.022
positive regulation of osteoblast proliferation GO:0033690 3 0.022
positive regulation of synaptic transmission GO:0050806 4 0.022
negative regulation of transferase activity GO:0051348 124 0.022
leukocyte mediated immunity GO:0002443 59 0.022
regulation of erbb signaling pathway GO:1901184 27 0.022
hair follicle morphogenesis GO:0031069 2 0.022
negative regulation of cell cycle GO:0045786 193 0.022
endocrine system development GO:0035270 26 0.022
tor signaling GO:0031929 39 0.021
central nervous system neuron axonogenesis GO:0021955 3 0.021
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.021
neuron projection development GO:0031175 106 0.021
epidermal growth factor receptor signaling pathway GO:0007173 39 0.021
cell chemotaxis GO:0060326 112 0.021
cellular response to histamine GO:0071420 3 0.021
prostate gland morphogenesis GO:0060512 1 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
neurotrophin signaling pathway GO:0038179 8 0.021
regulation of jun kinase activity GO:0043506 27 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
mast cell activation involved in immune response GO:0002279 4 0.021
spermatid differentiation GO:0048515 4 0.021
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.021
regulation of blood coagulation GO:0030193 42 0.020
calcium ion homeostasis GO:0055074 122 0.020
fc receptor signaling pathway GO:0038093 2 0.020
regulation of body fluid levels GO:0050878 99 0.020
non canonical wnt signaling pathway GO:0035567 14 0.020
cortisol secretion GO:0043400 4 0.020
negative regulation of cell cell adhesion GO:0022408 27 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.020
cerebellum development GO:0021549 2 0.020
regulation of pro b cell differentiation GO:2000973 1 0.020
blastoderm segmentation GO:0007350 2 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.020
regulation of calcium ion transport into cytosol GO:0010522 33 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
regulation of inflammatory response GO:0050727 46 0.019
melanin metabolic process GO:0006582 1 0.019
regulation of growth GO:0040008 165 0.019
positive regulation of calcium ion transport GO:0051928 51 0.019
erbb signaling pathway GO:0038127 44 0.019
acylglycerol homeostasis GO:0055090 14 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
cell division GO:0051301 168 0.019
positive regulation of interleukin 2 production GO:0032743 11 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
estrogen metabolic process GO:0008210 6 0.019
lymphoid progenitor cell differentiation GO:0002320 3 0.019
regulation of lipid metabolic process GO:0019216 96 0.019
vasodilation GO:0042311 4 0.019
protein catabolic process GO:0030163 325 0.018
response to epinephrine GO:0071871 2 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.018
meiosis i GO:0007127 4 0.018
leukocyte degranulation GO:0043299 11 0.018
regulation of lipase activity GO:0060191 37 0.018
protein dephosphorylation GO:0006470 81 0.018
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.018
cellular response to biotic stimulus GO:0071216 71 0.018
segmentation GO:0035282 4 0.018
regulation of actin filament based process GO:0032970 141 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
extracellular matrix organization GO:0030198 41 0.018
b cell proliferation GO:0042100 22 0.018
cytokine production GO:0001816 247 0.018
regulation of actin polymerization or depolymerization GO:0008064 56 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.017
positive regulation of protein export from nucleus GO:0046827 6 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
negative regulation of myeloid cell differentiation GO:0045638 42 0.017
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.017
negative regulation of cell cycle phase transition GO:1901988 89 0.017
negative regulation of cell death GO:0060548 345 0.017
cell cycle g1 s phase transition GO:0044843 80 0.017
cytosolic calcium ion transport GO:0060401 48 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
Mouse
visual behavior GO:0007632 2 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
regulation of ligase activity GO:0051340 29 0.017
negative regulation of coagulation GO:0050819 24 0.017
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 0.017
positive regulation of cell adhesion GO:0045785 84 0.017
positive regulation of catabolic process GO:0009896 310 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
response to growth factor GO:0070848 205 0.017
jak stat cascade GO:0007259 46 0.017
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
response to nitric oxide GO:0071731 4 0.017
cell type specific apoptotic process GO:0097285 125 0.017
regulation of secretion GO:0051046 194 0.016
actin filament polymerization GO:0030041 45 0.016
blood vessel development GO:0001568 172 0.016
Mouse
calcium ion transport into cytosol GO:0060402 48 0.016
defense response to other organism GO:0098542 129 0.016
actin cytoskeleton reorganization GO:0031532 37 0.016
regulation of secretion by cell GO:1903530 177 0.016
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
negative regulation of angiogenesis GO:0016525 39 0.016
regulation of interleukin 2 production GO:0032663 19 0.016
positive regulation of actin filament polymerization GO:0030838 38 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
negative regulation of ligase activity GO:0051352 8 0.016
immunoglobulin biosynthetic process GO:0002378 2 0.016
regulation of oxidoreductase activity GO:0051341 43 0.016
negative regulation of cell motility GO:2000146 104 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
mitotic spindle elongation GO:0000022 4 0.016
activated t cell proliferation GO:0050798 13 0.016
protein localization to organelle GO:0033365 280 0.016
negative regulation of neutrophil activation GO:1902564 1 0.015
regulation of ubiquitin protein transferase activity GO:0051438 28 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
negative regulation of blood pressure GO:0045776 3 0.015
mammary gland involution GO:0060056 1 0.015
cell junction assembly GO:0034329 67 0.015
regulation of hydrogen peroxide mediated programmed cell death GO:1901298 4 0.015
regulation of lymphocyte proliferation GO:0050670 64 0.015
regulation of adherens junction organization GO:1903391 21 0.015
response to hyperoxia GO:0055093 4 0.015
positive regulation of phagocytosis GO:0050766 15 0.015
ion homeostasis GO:0050801 230 0.015
phospholipid metabolic process GO:0006644 99 0.015
regulation of cell cell adhesion GO:0022407 57 0.015
regulation of antigen receptor mediated signaling pathway GO:0050854 10 0.015
regulation of cytokine production GO:0001817 232 0.015
negative regulation of cellular component movement GO:0051271 106 0.015
cellular response to lipid GO:0071396 127 0.015
regulation of t cell activation GO:0050863 77 0.015
cell cell junction maintenance GO:0045217 4 0.015
b cell receptor signaling pathway GO:0050853 18 0.015
negative regulation of mitotic cell cycle GO:0045930 102 0.015
startle response GO:0001964 3 0.015
dendritic spine maintenance GO:0097062 1 0.015
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.015
leukocyte differentiation GO:0002521 98 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
oocyte development GO:0048599 1 0.015
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.015
regulation of intracellular protein transport GO:0033157 123 0.014
membrane invagination GO:0010324 10 0.014
cellular homeostasis GO:0019725 196 0.014

RAPGEF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.051
musculoskeletal system disease DOID:17 223 0.035
disease of metabolism DOID:0014667 295 0.032
cancer DOID:162 167 0.030
disease of cellular proliferation DOID:14566 174 0.030
organ system cancer DOID:0050686 164 0.030
muscular disease DOID:0080000 114 0.028
muscle tissue disease DOID:66 113 0.028
myopathy DOID:423 104 0.021
bone disease DOID:0080001 88 0.019
connective tissue disease DOID:65 109 0.019
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
central nervous system disease DOID:331 186 0.016
muscular dystrophy DOID:9884 51 0.015