|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.991
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.918
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.881
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.872
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.864
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.837
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.793
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.769
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.761
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.751
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.736
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.729
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.725
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.706
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.696
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.692
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.685
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.680
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.663
|
|
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.631
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.592
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.585
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.575
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.560
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.554
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.520
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.519
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.518
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.514
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.495
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.494
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.465
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.455
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.448
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.442
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.435
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.428
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.427
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.423
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.398
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.398
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.397
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.393
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.379
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.362
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.360
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.350
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.343
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.338
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.335
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.333
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.332
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.330
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.319
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
4 |
0.310
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.307
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.294
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.287
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.287
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.286
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.285
|
Mouse |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.283
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.266
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.258
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.258
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.258
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.252
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.242
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.237
|
Mouse |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.237
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.232
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.230
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.229
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.229
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.228
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.226
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.225
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.218
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.210
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.209
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.208
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.208
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.205
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.204
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.196
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.193
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.187
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.182
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.181
|
|
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
4 |
0.181
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.177
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.176
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.175
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.175
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.169
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.169
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.166
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.164
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.164
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.163
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.162
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.154
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.153
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.150
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.150
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.148
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.148
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.143
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.140
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.140
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.138
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.138
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.137
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.133
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.133
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.132
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.130
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.130
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.130
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.129
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.128
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.128
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.126
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.124
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.123
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.122
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.122
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.122
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.120
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.118
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.113
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.113
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.110
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.110
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.108
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.104
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.104
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.103
|
|
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.103
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.103
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.103
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.100
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.100
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.099
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.099
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.098
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.097
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.097
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.096
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.096
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.095
|
|
|
|
maintenance of sister chromatid cohesion
|
GO:0034086 |
6 |
0.094
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.094
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.093
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.093
|
|
|
|
telomere capping
|
GO:0016233 |
5 |
0.093
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.090
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.090
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.089
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.089
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.089
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.089
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.087
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.085
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.084
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.084
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.084
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.084
|
|
|
|
mitotic metaphase plate congression
|
GO:0007080 |
14 |
0.083
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.082
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.081
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.081
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.080
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.080
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.080
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.079
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.079
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.079
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.078
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.077
|
|
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
6 |
0.076
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.076
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.076
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.076
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.075
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.075
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
12 |
0.074
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.073
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.073
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.073
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.073
|
|
|
|
postreplication repair
|
GO:0006301 |
12 |
0.073
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.071
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.070
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.070
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.070
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.070
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.068
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.068
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.067
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.067
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.066
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.065
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.062
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.061
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.061
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.060
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.060
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.060
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.059
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.059
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.058
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.057
|
Mouse |
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.057
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.057
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.057
|
|
|
|
attachment of mitotic spindle microtubules to kinetochore
|
GO:0051315 |
3 |
0.057
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.057
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.056
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.056
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.056
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.055
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.055
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.055
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.053
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.053
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.053
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.052
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.051
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.051
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.050
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.050
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.050
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.049
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.049
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.049
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.049
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.049
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.048
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.048
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.048
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.048
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.048
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.047
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.047
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.046
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.046
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.045
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.045
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.045
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.045
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.045
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.045
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.044
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.043
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.043
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.042
|
|
|
|
sister chromatid biorientation
|
GO:0031134 |
2 |
0.041
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.041
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.041
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.041
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.041
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.040
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.040
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.040
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.039
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.039
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.039
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.039
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.039
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.039
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.038
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.038
|
|
|
|
system process
|
GO:0003008 |
349 |
0.037
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.037
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.037
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.037
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.037
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.036
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.036
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.036
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.036
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.036
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.036
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.036
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.036
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.035
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.035
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.035
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.035
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.035
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.035
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.035
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.034
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.034
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.034
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.034
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.034
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.034
|
|
|
|
somatic hypermutation of immunoglobulin genes
|
GO:0016446 |
1 |
0.034
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.033
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.033
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.033
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.032
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.032
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.032
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.031
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.031
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.031
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.031
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.030
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.030
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.030
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.030
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.030
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.030
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.030
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.030
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.029
|
Mouse |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.029
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.029
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.029
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.029
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.029
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.029
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.029
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.028
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.028
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.028
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.028
|
|
|
|
mitotic dna replication checkpoint
|
GO:0033314 |
2 |
0.028
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.028
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.028
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.027
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.027
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.026
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.026
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.026
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.026
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.026
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.026
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.026
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.025
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.025
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.025
|
|
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.025
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.025
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.025
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
6 |
0.025
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.025
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.025
|
|
|
|
regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043516 |
20 |
0.024
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.024
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.024
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.024
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.024
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.024
|
|
|
|
maintenance of mitotic sister chromatid cohesion
|
GO:0034088 |
6 |
0.023
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.023
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.023
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.023
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.023
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.023
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.023
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.023
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.023
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.023
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.023
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.022
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.022
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.022
|
|
|
|
head development
|
GO:0060322 |
108 |
0.022
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.022
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
6 |
0.022
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.022
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.021
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.021
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.021
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.021
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.021
|
|
|
|
dna endoreduplication
|
GO:0042023 |
5 |
0.021
|
|
|
|
establishment of chromosome localization
|
GO:0051303 |
20 |
0.021
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.021
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.021
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.021
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.021
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.021
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.021
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.021
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.020
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.020
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.020
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.020
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.020
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.020
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
5 |
0.020
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.020
|
|
|
|
gmp metabolic process
|
GO:0046037 |
4 |
0.020
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.020
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.020
|
|
|
|
positive regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043517 |
8 |
0.020
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.020
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.019
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.019
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.019
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.019
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.019
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.019
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.019
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.019
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.019
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.019
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.019
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.019
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.019
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.018
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.018
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.018
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.018
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.018
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.018
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.018
|
|
|
|
growth
|
GO:0040007 |
202 |
0.018
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.018
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.018
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.018
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.017
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.017
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.017
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.017
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.017
|
|
|
|
telomere organization
|
GO:0032200 |
33 |
0.017
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.016
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.016
|
|
|
|
histone deubiquitination
|
GO:0016578 |
16 |
0.016
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.016
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.016
|
|
|
|
regulation of glycoprotein metabolic process
|
GO:1903018 |
19 |
0.016
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.016
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.016
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.016
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.016
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.016
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
15 |
0.016
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.016
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.016
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.016
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.016
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.016
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.016
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.016
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.016
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.016
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.016
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.016
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.015
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.015
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.015
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.015
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.015
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.015
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.015
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.015
|
|
|
|
somatic diversification of immune receptors via somatic mutation
|
GO:0002566 |
1 |
0.015
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
6 |
0.015
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.015
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.015
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.015
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.015
|
|
