|
protein polyubiquitination
|
GO:0000209 |
110 |
0.999
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.999
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.999
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.998
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.997
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.991
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.990
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.990
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.990
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.984
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.967
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.941
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.940
|
|
|
protein linear polyubiquitination
|
GO:0097039 |
5 |
0.935
|
|
|
keratinization
|
GO:0031424 |
2 |
0.914
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.901
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.895
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.878
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
12 |
0.873
|
|
|
viral process
|
GO:0016032 |
146 |
0.869
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.831
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.829
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.822
|
Human |
|
viral life cycle
|
GO:0019058 |
132 |
0.776
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.740
|
|
|
entry into cell of other organism involved in symbiotic interaction
|
GO:0051806 |
25 |
0.652
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.650
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.636
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.633
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.630
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.613
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.545
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.542
|
|
|
immune response
|
GO:0006955 |
307 |
0.522
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.509
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.471
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.461
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.431
|
Mouse |
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.395
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.371
|
|
|
entry into host
|
GO:0044409 |
25 |
0.346
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.324
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.318
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.316
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.308
|
|
|
negative regulation of interleukin 2 secretion
|
GO:1900041 |
2 |
0.297
|
|
|
entry into host cell
|
GO:0030260 |
25 |
0.294
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.293
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.292
|
|
|
regulation of intracellular transport of viral material
|
GO:1901252 |
2 |
0.290
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.290
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.280
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.280
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.273
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.263
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.263
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.263
|
|
|
positive regulation of viral entry into host cell
|
GO:0046598 |
3 |
0.259
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.247
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.246
|
Human |
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.239
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.239
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.237
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.236
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.235
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.216
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.215
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.215
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.208
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.204
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.202
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.195
|
Mouse |
|
movement in environment of other organism involved in symbiotic interaction
|
GO:0052192 |
25 |
0.188
|
|
|
negative regulation of viral entry into host cell
|
GO:0046597 |
12 |
0.180
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.170
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.170
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.169
|
|
|
negative regulation of intracellular transport of viral material
|
GO:1901253 |
2 |
0.165
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.163
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.160
|
|
|
negative regulation of calcium ion import
|
GO:0090281 |
1 |
0.158
|
|
|
cd40 signaling pathway
|
GO:0023035 |
3 |
0.154
|
Human |
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.153
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.150
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.147
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.146
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.145
|
Mouse |
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.145
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.144
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.143
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.143
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.141
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.136
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.135
|
Human |
|
regulation of viral entry into host cell
|
GO:0046596 |
17 |
0.135
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.126
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.123
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
4 |
0.122
|
|
|
secretion
|
GO:0046903 |
254 |
0.112
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.112
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.112
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.107
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.107
|
|
|
protein processing
|
GO:0016485 |
226 |
0.107
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.106
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.105
|
|
|
response to virus
|
GO:0009615 |
126 |
0.101
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.101
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.100
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.099
|
|
|
viral entry into host cell
|
GO:0046718 |
24 |
0.097
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.096
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.095
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.093
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.091
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.091
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.091
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.090
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.089
|
|
|
entry into other organism involved in symbiotic interaction
|
GO:0051828 |
25 |
0.088
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.088
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.084
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.083
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.082
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.080
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.078
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.077
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.076
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.075
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.075
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.074
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.074
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.074
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.073
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.072
|
|
|
regeneration
|
GO:0031099 |
4 |
0.070
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.068
|
Mouse |
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.067
|
Human |
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.067
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.066
|
|
|
regulation of calcium ion import
|
GO:0090279 |
11 |
0.065
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.065
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.063
|
Mouse |
|
epithelium development
|
GO:0060429 |
227 |
0.063
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.063
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.062
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.061
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.061
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.060
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.060
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.058
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.058
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.058
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.057
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.057
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.056
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.056
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.056
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.055
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.055
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.055
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.054
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.054
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.053
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.053
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.053
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.053
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.052
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.052
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.052
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.052
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.052
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.051
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.051
|
|
|
toll like receptor 3 signaling pathway
|
GO:0034138 |
4 |
0.051
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.051
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.051
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.050
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.050
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.050
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.050
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.049
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.049
|
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
0.049
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.048
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.048
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.048
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.048
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.047
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.047
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
7 |
0.047
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.047
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.047
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.044
|
Human |
|
positive regulation of interleukin 8 biosynthetic process
|
GO:0045416 |
8 |
0.044
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.044
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.044
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.044
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.043
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.043
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.043
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.042
|
Human |
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.042
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.042
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.042
|
Human |
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.041
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.041
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.041
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.041
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.041
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.041
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.040
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.040
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.039
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.039
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.038
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.038
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.038
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.038
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.038
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.037
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.037
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.037
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.037
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.037
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.037
|
Mouse |
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.036
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.035
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.035
|
|
|
negative regulation of calcium ion transport
|
GO:0051926 |
19 |
0.035
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.035
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.035
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.035
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.035
|
Mouse |
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.034
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.034
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.034
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.034
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.033
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.033
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.033
|
Mouse |
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.033
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.033
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.033
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.033
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.032
|
|
|
positive regulation of rig i signaling pathway
|
GO:1900246 |
4 |
0.032
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.032
|
Mouse |
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.032
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.031
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.031
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.031
|
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.031
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.031
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.030
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.030
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.030
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.029
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.029
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.029
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.029
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.029
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.029
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.028
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.028
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.028
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.028
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.028
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.028
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.027
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.027
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.026
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.026
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.026
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.026
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.026
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.026
|
|
|
multi organism intracellular transport
|
GO:1902583 |
14 |
0.026
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.026
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.025
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.025
|
|
|
multi organism transport
|
GO:0044766 |
14 |
0.025
|
|
|
cation transport
|
GO:0006812 |
331 |
0.024
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.024
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.024
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.024
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.024
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.023
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.023
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.023
|
Mouse |
|
chemokine biosynthetic process
|
GO:0042033 |
4 |
0.023
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.023
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.023
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.023
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.023
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.023
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.022
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.021
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.021
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.021
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.021
|
|
|
positive regulation of viral process
|
GO:0048524 |
37 |
0.021
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.021
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
22 |
0.021
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.021
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.021
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.021
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.021
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.021
|
Mouse |
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.021
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.020
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.020
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.020
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.020
|
Mouse |
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.020
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.020
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.019
|
|
|
memory
|
GO:0007613 |
3 |
0.019
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.019
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.019
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.019
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.018
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.018
|
Mouse |
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.018
|
Mouse |
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.018
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.018
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.018
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.018
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.018
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.018
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.018
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.018
|
Mouse |
|
calcium ion import
|
GO:0070509 |
23 |
0.017
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.017
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.017
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.017
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.017
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.017
|
Mouse |
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.017
|
Human |
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.016
|
Mouse |
|
response to oxidative stress
|
GO:0006979 |
121 |
0.016
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.016
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.016
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.016
|
|
|
transport of virus
|
GO:0046794 |
14 |
0.016
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.016
|
Mouse |
|
cell adhesion
|
GO:0007155 |
325 |
0.016
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.016
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.016
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.016
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.016
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.016
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.015
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.015
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.015
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.015
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.015
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.015
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.015
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.015
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.015
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.015
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.015
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.015
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.015
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.015
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.015
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.015
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.015
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.015
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.015
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.015
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.014
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.014
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.014
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.014
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.014
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.014
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.014
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.014
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.014
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.014
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.014
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.014
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.014
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.014
|
|
|
segmentation
|
GO:0035282 |
4 |
0.014
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.014
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.013
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.013
|
Mouse |
|
isg15 protein conjugation
|
GO:0032020 |
5 |
0.013
|
|
|
brain development
|
GO:0007420 |
97 |
0.013
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.013
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.013
|
|
|
negative regulation of toll like receptor 3 signaling pathway
|
GO:0034140 |
2 |
0.013
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.013
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.013
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.013
|
|
|
movement in host environment
|
GO:0052126 |
25 |
0.013
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.013
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.013
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.013
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.013
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.013
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
20 |
0.013
|
|
|
protein trimerization
|
GO:0070206 |
20 |
0.013
|
|
|
long term memory
|
GO:0007616 |
2 |
0.013
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
4 |
0.013
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.013
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.013
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
4 |
0.013
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.013
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.013
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.013
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.013
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.013
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.013
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.013
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.012
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.012
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
7 |
0.012
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.012
|
|
|
immune system development
|
GO:0002520 |
195 |
0.012
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.012
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.012
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.012
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.012
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.012
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.012
|
|
|
uronic acid metabolic process
|
GO:0006063 |
16 |
0.012
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.012
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.012
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.012
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.012
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.012
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.012
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.012
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.012
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.012
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.012
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.012
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.012
|
|
|
chronic inflammatory response
|
GO:0002544 |
2 |
0.012
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.012
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.011
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.011
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.011
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.011
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.011
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.011
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.011
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.011
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.011
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.011
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.011
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.011
|
Mouse |
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.011
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.011
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.011
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.011
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.011
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.011
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.011
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.011
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.011
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.011
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.011
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.011
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.011
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.011
|
Zebrafish |
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.011
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
17 |
0.011
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.010
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.010
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.010
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.010
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.010
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.010
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.010
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.010
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.010
|
|