|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.853
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.810
|
Yeast |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.786
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.769
|
Yeast Worm Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.732
|
Yeast Worm Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.727
|
Yeast Worm Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.720
|
Human Yeast Worm Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.718
|
Yeast Worm Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.715
|
Fly |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.694
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.677
|
Yeast Worm Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.638
|
Yeast Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.619
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.612
|
Yeast Worm Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.585
|
Yeast Worm Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.571
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.567
|
Yeast Worm Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.566
|
Human Yeast |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.516
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.514
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.506
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.502
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.475
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.474
|
Yeast Worm Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.470
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.465
|
Yeast Worm Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.456
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.441
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.439
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.436
|
Yeast Worm Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.431
|
Human Fly |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.424
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.416
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.404
|
Yeast Worm Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.397
|
Yeast Worm Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.394
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.393
|
Human Yeast Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.387
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.378
|
Human Worm |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.377
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.369
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.368
|
Human Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.368
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.358
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.355
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.352
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.350
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.345
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.344
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.337
|
Yeast Worm Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.318
|
Human Worm |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.317
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.309
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.289
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.284
|
Human Yeast Worm Fly |
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.280
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.278
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.275
|
Yeast Worm Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.264
|
Yeast Worm Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.262
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.261
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.256
|
Yeast Worm Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.255
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.252
|
Yeast Worm Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.233
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.221
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.221
|
Yeast Worm Fly |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.217
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.211
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.199
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.198
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.186
|
Human Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.183
|
|
|
|
growth
|
GO:0040007 |
202 |
0.170
|
Yeast Fly |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.169
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.163
|
Yeast Worm Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.161
|
Yeast |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.158
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.158
|
Yeast Worm Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.151
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.140
|
Yeast Worm Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.139
|
Worm |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.137
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.137
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.132
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.131
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.129
|
Worm Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.123
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.122
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.115
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.112
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.112
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.109
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.107
|
Yeast Worm Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.107
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.107
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.103
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.103
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.103
|
Human Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.101
|
Human |
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.100
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.100
|
Human |
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.100
|
Human Worm Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.098
|
Human Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.098
|
Worm |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.098
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.097
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.095
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.094
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.092
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.092
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.092
|
Human Worm Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.092
|
Human Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.089
|
Fly |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.089
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.088
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.086
|
Worm |
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.085
|
Fly |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.085
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.084
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.083
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.083
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.082
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.081
|
Human Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.080
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.079
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.079
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.079
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.079
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.078
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.078
|
Yeast Worm |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.078
|
Yeast Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.077
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.076
|
Fly |
|
|
acetylcholine transport
|
GO:0015870 |
1 |
0.076
|
Worm |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.076
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.076
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.075
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.075
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.075
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.075
|
Human |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.074
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.074
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.073
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.072
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.071
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.070
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.069
|
Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.069
|
Worm |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.069
|
Fly |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.069
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.069
|
Human Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.068
|
Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.067
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.065
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.065
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.065
|
Human Fly |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.064
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.063
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.061
|
Yeast |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.061
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.060
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
2 |
0.060
|
Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.060
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.060
|
Worm |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.060
|
Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.059
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.057
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.057
|
Human |
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.056
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.056
|
Worm |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.056
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.055
|
Fly |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.054
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.054
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.053
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.053
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.052
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.052
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.052
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.052
|
Yeast |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.051
|
Human Fly |
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.051
|
Worm |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.051
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.051
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.051
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.051
|
Human |
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.050
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.050
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.049
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.049
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.049
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.049
|
Yeast Worm Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.048
|
|
|
|
mitotic cytokinetic process
|
GO:1902410 |
2 |
0.048
|
Fly |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.048
|
Fly |
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.048
|
Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.047
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.047
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.047
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.047
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.047
|
Fly |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.047
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.047
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.046
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.046
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.046
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.045
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.045
|
|
|
|
negative regulation of actin filament bundle assembly
|
GO:0032232 |
9 |
0.044
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.044
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.044
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.043
|
Worm |
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.043
|
Worm |
|
|
taxis
|
GO:0042330 |
157 |
0.043
|
Human Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.043
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.043
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.043
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.042
|
Worm |
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.042
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.042
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.042
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.042
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.042
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.041
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.041
|
Fly |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.041
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.041
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.041
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.041
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.040
|
Yeast |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.040
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.040
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.040
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.039
|
Human |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.039
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.039
|
Human |
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.039
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.038
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.038
|
Fly |
|
|
regulation of attachment of spindle microtubules to kinetochore
|
GO:0051988 |
9 |
0.038
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.038
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.038
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.038
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.037
|
Human |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.037
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.037
|
|
|
|
mating
|
GO:0007618 |
1 |
0.037
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.037
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.036
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.036
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.036
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.036
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.036
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.036
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.035
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.035
|
Worm |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.035
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.035
|
Yeast |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.035
|
Worm Fly |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.035
|
Worm |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.035
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.034
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.034
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.034
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.034
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.034
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.033
|
Fly |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.033
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.033
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.033
|
Worm Fly |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.033
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.033
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.033
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.032
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.032
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.032
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.032
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.032
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.031
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.031
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.031
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.031
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.031
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.031
|
Human |
|
|
viral process
|
GO:0016032 |
146 |
0.031
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.031
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.030
|
Fly |
|
|
behavior
|
GO:0007610 |
112 |
0.030
|
Worm |
|
|
negative regulation of stress fiber assembly
|
GO:0051497 |
8 |
0.030
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.030
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.030
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.029
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.029
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.029
|
Human Worm |
|
|
memory
|
GO:0007613 |
3 |
0.029
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.029
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.029
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.029
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.029
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.029
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.029
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.029
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.028
|
|
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.028
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.028
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.028
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.028
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.028
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.028
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.027
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.027
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.027
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.027
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.027
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.027
|
Yeast |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.027
|
|
|
|
head development
|
GO:0060322 |
108 |
0.027
|
Human |
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.026
|
Human |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.026
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.026
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.026
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.026
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.026
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.025
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.025
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.025
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.025
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.025
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.025
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.024
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.024
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.024
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.024
|
Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.024
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.024
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.024
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.024
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.024
|
Human Fly |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.024
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.024
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.024
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.024
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.024
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.024
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.024
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.023
|
|
|
|
regulation of respiratory burst
|
GO:0060263 |
8 |
0.023
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.023
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.023
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.023
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.023
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.023
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.023
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.023
|
Yeast |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.023
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.023
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.023
|
Worm |
|
|
hippo signaling
|
GO:0035329 |
20 |
0.023
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.022
|
Fly |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.022
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.022
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.022
|
Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.022
|
Worm |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.022
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.022
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.022
|
|
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.022
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.022
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.022
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.022
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.022
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.022
|
Worm |
|
|
organelle fusion
|
GO:0048284 |
36 |
0.021
|
Yeast |
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.021
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.021
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.021
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.021
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
Fly |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.021
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.021
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.021
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.021
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.020
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.020
|
Fly |
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.020
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.020
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.020
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.020
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.020
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.020
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.020
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.020
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.020
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.020
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.020
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.020
|
Human |
|
|
nuclear import
|
GO:0051170 |
106 |
0.020
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.020
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.019
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.019
|
Worm |
|
|
acetylcholine secretion
|
GO:0061526 |
1 |
0.019
|
Worm |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.019
|
Worm |
|
|
skeletal myofibril assembly
|
GO:0014866 |
3 |
0.019
|
Worm |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.019
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.019
|
Human |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.019
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.019
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.019
|
|
|
|
glucose import
|
GO:0046323 |
24 |
0.019
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.019
|
Fly |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.018
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.018
|
Worm |
|
|
vitamin transmembrane transport
|
GO:0035461 |
4 |
0.018
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.018
|
Human Fly |
|
|
thiamine transmembrane transport
|
GO:0071934 |
2 |
0.018
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.018
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.018
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.018
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.018
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.018
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.018
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.018
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
9 |
0.017
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.017
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.017
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.017
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.017
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.017
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.017
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.017
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.017
|
Fly |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.017
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.017
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.017
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.017
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.017
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.017
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.017
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.017
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.017
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.017
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.016
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.016
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.016
|
Yeast |
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.016
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.016
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.016
|
Fly |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.016
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.016
|
|
|
|
assembly of actomyosin apparatus involved in cytokinesis
|
GO:0000912 |
1 |
0.016
|
Worm Fly |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.016
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.016
|
Human |
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.016
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.016
|
Human |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.016
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.016
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.016
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.016
|
Yeast |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.016
|
Human |
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.016
|
|
|
|
hexose transport
|
GO:0008645 |
30 |
0.016
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.016
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.015
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.015
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
4 |
0.015
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.015
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.015
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.015
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.015
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.015
|
Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.015
|
|
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
19 |
0.015
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.015
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.015
|
|
