|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.920
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.880
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.785
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.775
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.685
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.664
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.652
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.645
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.644
|
Human |
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.638
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.630
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.591
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.575
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.513
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.513
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.509
|
|
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.504
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.474
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.454
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.453
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.449
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.448
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.445
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.433
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.432
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.432
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.423
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.420
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.415
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.413
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.411
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.400
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.391
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.386
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.385
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.384
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.380
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.376
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.375
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.364
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.363
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.360
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.359
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.353
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.347
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.347
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.343
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.343
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.339
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.337
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.333
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.328
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.328
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.324
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.318
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.318
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.318
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.316
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.307
|
Human |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.299
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.293
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.292
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.289
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.282
|
Human |
|
|
visual behavior
|
GO:0007632 |
2 |
0.281
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.276
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.275
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.270
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.268
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.265
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.264
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.263
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.261
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.255
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.252
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.251
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.251
|
Human |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.245
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.243
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.243
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.240
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.240
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.240
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.239
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.235
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.233
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.230
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.229
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.227
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.227
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.226
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.223
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.223
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.222
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.220
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.217
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.215
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.213
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.212
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.211
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.210
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.208
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.207
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.207
|
Human |
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.203
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
6 |
0.202
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.202
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.202
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.202
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.200
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.200
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.199
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.193
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.193
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.193
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.193
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.191
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.191
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.190
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.188
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.188
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.182
|
Human |
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.181
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.180
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.176
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.176
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.176
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.175
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.175
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.174
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.173
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.171
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.170
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.164
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.163
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.162
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.159
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.159
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.159
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.158
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.157
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
3 |
0.157
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.156
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.155
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.154
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.153
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.153
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.152
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.152
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.152
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.150
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.148
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.148
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.147
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.147
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.147
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.147
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.145
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.145
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.145
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.144
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.144
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.143
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.141
|
Human |
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.140
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.140
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.139
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.138
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.138
|
|
|
|
growth
|
GO:0040007 |
202 |
0.138
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.137
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.137
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.136
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.136
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.132
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.131
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.131
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.130
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.130
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.129
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.129
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.129
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.128
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.127
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
2 |
0.127
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.126
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.126
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.125
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.124
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.123
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.123
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.122
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.121
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.121
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.121
|
Human |
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.120
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.120
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.120
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.119
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.119
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.119
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.118
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.117
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.117
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.116
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.116
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.114
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.114
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.113
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.112
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.112
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.112
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.112
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.111
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.111
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.110
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.110
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.110
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.110
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.110
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.108
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.107
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.105
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.105
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.103
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
11 |
0.103
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.102
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.100
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.099
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.099
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.099
|
Human |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.098
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.097
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.096
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.095
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.095
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.095
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.095
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.094
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.094
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.094
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.093
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.093
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.092
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.092
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.091
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.090
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.090
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.089
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.089
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.089
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.089
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.088
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.088
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.086
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.086
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.085
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.085
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.085
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.085
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.085
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.084
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.084
|
Human |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.083
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.083
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.083
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.083
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.082
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.082
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.082
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.082
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.082
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.082
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.082
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.081
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.081
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.081
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.081
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.080
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.080
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.079
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.079
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.078
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.077
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.077
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.077
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.076
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.076
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.075
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.075
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.075
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.074
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.074
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.074
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.074
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.073
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.073
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.073
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.073
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.072
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.072
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.072
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.070
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.070
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.070
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.070
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.069
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.069
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.068
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.068
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.067
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.067
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.067
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.067
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.067
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.066
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.066
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.066
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.065
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.065
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.065
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.065
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.065
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.065
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.065
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.064
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.064
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.063
|
|
|
|
negative regulation of ras gtpase activity
|
GO:0034261 |
6 |
0.063
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.063
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.063
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.062
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.062
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.062
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.062
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.062
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.061
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.060
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.060
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.060
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.060
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.059
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.059
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.058
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.058
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.057
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.057
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.056
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.056
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.056
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.056
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.055
|
|
|
|
head development
|
GO:0060322 |
108 |
0.054
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.054
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.054
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.054
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.054
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.053
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.052
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.052
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.052
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.052
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.052
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.051
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.051
|
|
|
|
regulation of ruffle assembly
|
GO:1900027 |
8 |
0.051
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.050
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.050
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.050
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.049
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.049
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.049
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.048
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.048
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.048
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.047
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.047
|
|
|
|
regulation of apoptotic cell clearance
|
GO:2000425 |
5 |
0.047
|
|
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.047
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.047
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.046
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.046
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.046
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.045
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.045
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.045
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
16 |
0.045
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.045
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.045
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.044
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.044
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.044
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.044
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.043
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.043
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.043
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.043
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.043
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.043
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.042
|
Mouse |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.042
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.042
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.042
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.041
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.040
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.040
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.040
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.039
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.038
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.038
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.038
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.038
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.038
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.038
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.037
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.037
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.037
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.037
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.037
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.037
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.036
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.036
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.036
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.036
|
|
|
|
exploration behavior
|
GO:0035640 |
1 |
0.036
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.036
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.036
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.036
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.036
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.035
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.035
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.035
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.035
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.035
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.035
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.035
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.035
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.034
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.034
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.034
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.034
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.033
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.033
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.033
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.033
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.032
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.032
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.032
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.032
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
5 |
0.032
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.032
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.032
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.032
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.031
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.031
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.031
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.031
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.031
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.031
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.031
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.031
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.031
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.031
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.031
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.030
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.030
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.030
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.030
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.030
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.030
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.029
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.029
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.029
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.029
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.029
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.029
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.029
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.028
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.028
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.028
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.028
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.028
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.028
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.028
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.028
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.027
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.027
|
|
