Homo sapiens

129 known processes

RNF4

ring finger protein 4

(Aliases: SLX5,SNURF)

RNF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.993
Rat
protein modification by small protein conjugation GO:0032446 342 0.989
Rat
protein ubiquitination GO:0016567 314 0.980
Rat
protein k48 linked ubiquitination GO:0070936 38 0.903
Rat
protein autoubiquitination GO:0051865 37 0.493
Rat
modification dependent protein catabolic process GO:0019941 209 0.475
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.319
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.255
post embryonic development GO:0009791 2 0.239
ubiquitin dependent protein catabolic process GO:0006511 206 0.238
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.228
protein monoubiquitination GO:0006513 39 0.208
pharynx development GO:0060465 1 0.203
cellular macromolecule catabolic process GO:0044265 380 0.202
modification dependent macromolecule catabolic process GO:0043632 212 0.194
protein catabolic process GO:0030163 325 0.186
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.164
cellular protein catabolic process GO:0044257 261 0.135
apoptotic signaling pathway GO:0097190 268 0.102
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.092
histone ubiquitination GO:0016574 31 0.088
proteasomal protein catabolic process GO:0010498 176 0.087
positive regulation of apoptotic process GO:0043065 246 0.084
positive regulation of cell death GO:0010942 263 0.078
regulation of apoptotic signaling pathway GO:2001233 175 0.078
morphogenesis of embryonic epithelium GO:0016331 4 0.075
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.075
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.074
positive regulation of apoptotic signaling pathway GO:2001235 70 0.073
cellular response to dna damage stimulus GO:0006974 379 0.069
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.068
segmentation GO:0035282 4 0.066
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.061
posttranscriptional regulation of gene expression GO:0010608 213 0.058
extrinsic apoptotic signaling pathway GO:0097191 119 0.056
regulation of cellular response to stress GO:0080135 244 0.054
regulation of protein stability GO:0031647 87 0.050
i kappab kinase nf kappab signaling GO:0007249 166 0.050
enzyme linked receptor protein signaling pathway GO:0007167 303 0.049
histone modification GO:0016570 251 0.049
positive regulation of programmed cell death GO:0043068 249 0.049
negative regulation of viral process GO:0048525 66 0.048
protein k63 linked ubiquitination GO:0070534 31 0.047
Rat
cation transport GO:0006812 331 0.047
negative regulation of multicellular organismal process GO:0051241 317 0.046
metal ion transport GO:0030001 272 0.045
regulation of locomotion GO:0040012 329 0.045
dna conformation change GO:0071103 113 0.044
regulation of proteolysis GO:0030162 293 0.042
negative regulation of apoptotic process GO:0043066 316 0.042
viral release from host cell GO:0019076 21 0.040
positive regulation of organelle organization GO:0010638 195 0.040
digestive system development GO:0055123 75 0.040
positive regulation of viral entry into host cell GO:0046598 3 0.039
negative regulation of programmed cell death GO:0043069 321 0.037
vesicle mediated transport GO:0016192 371 0.036
rna interference GO:0016246 4 0.036
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.035
rna processing GO:0006396 255 0.035
multi organism cellular process GO:0044764 156 0.034
adult locomotory behavior GO:0008344 1 0.034
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.034
dna repair GO:0006281 198 0.033
protein localization to organelle GO:0033365 280 0.033
regulation of protein localization GO:0032880 296 0.033
mrna metabolic process GO:0016071 175 0.032
intracellular receptor signaling pathway GO:0030522 104 0.032
negative regulation of multi organism process GO:0043901 92 0.032
regulation of viral release from host cell GO:1902186 20 0.031
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.031
immune effector process GO:0002252 159 0.031
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.030
interspecies interaction between organisms GO:0044419 156 0.030
androgen receptor signaling pathway GO:0030521 34 0.030
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.030
regulation of protein ubiquitination GO:0031396 95 0.029
response to oxygen containing compound GO:1901700 369 0.029
mapk cascade GO:0000165 288 0.029
positive regulation of cellular component organization GO:0051130 376 0.029
regulation of protein catabolic process GO:0042176 155 0.028
regulation of interleukin 2 secretion GO:1900040 2 0.028
innate immune response GO:0045087 178 0.028
chromatin organization GO:0006325 351 0.028
chromosome condensation GO:0030261 15 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.027
nuclear division GO:0000280 128 0.026
regulation of cytoskeleton organization GO:0051493 177 0.026
tube development GO:0035295 125 0.026
negative regulation of protein maturation GO:1903318 142 0.026
negative regulation of cell death GO:0060548 345 0.026
Rat
positive regulation of cellular component biogenesis GO:0044089 158 0.026
regulation of cell differentiation GO:0045595 393 0.026
locomotory behavior GO:0007626 1 0.025
positive regulation of transferase activity GO:0051347 227 0.025
immune response GO:0006955 307 0.025
cell development GO:0048468 328 0.024
thymus development GO:0048538 3 0.024
negative regulation of locomotion GO:0040013 118 0.024
chromosome segregation GO:0007059 114 0.024
regulation of actin filament based process GO:0032970 141 0.024
tissue morphogenesis GO:0048729 96 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
negative regulation of cell cycle phase transition GO:1901988 89 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.024
regulation of mapk cascade GO:0043408 262 0.024
regulation of viral process GO:0050792 103 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.024
anterior posterior axis specification GO:0009948 2 0.023
protein maturation GO:0051604 233 0.023
negative regulation of developmental process GO:0051093 247 0.023
chromatin modification GO:0016568 298 0.022
negative regulation of cell cycle GO:0045786 193 0.022
ion transmembrane transport GO:0034220 338 0.022
memory GO:0007613 3 0.021
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.021
peripheral nervous system development GO:0007422 2 0.021
epithelium migration GO:0090132 119 0.021
amine metabolic process GO:0009308 44 0.020
covalent chromatin modification GO:0016569 254 0.020
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.020
regulation of cell cycle GO:0051726 393 0.020
lymphocyte activation GO:0046649 133 0.020
divalent inorganic cation transport GO:0072511 158 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
positive regulation of protein ubiquitination GO:0031398 53 0.020
regulation of intracellular transport GO:0032386 195 0.020
response to radiation GO:0009314 151 0.019
Rat
inorganic ion transmembrane transport GO:0098660 231 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
organelle fission GO:0048285 149 0.019
transmembrane transport GO:0055085 399 0.019
protein polymerization GO:0051258 71 0.019
regulation of kinase activity GO:0043549 314 0.019
microtubule based process GO:0007017 210 0.019
cellular protein complex assembly GO:0043623 188 0.019
regulation of peptidase activity GO:0052547 180 0.019
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.019
response to biotic stimulus GO:0009607 276 0.019
cytokine production GO:0001816 247 0.018
negative regulation of glial cell proliferation GO:0060253 2 0.018
regulation of innate immune response GO:0045088 97 0.018
regulation of dna repair GO:0006282 47 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.018
regulation of protein transport GO:0051223 213 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.018
regulation of response to external stimulus GO:0032101 222 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
cellular ketone metabolic process GO:0042180 80 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
nitrogen compound transport GO:0071705 191 0.017
cerebellum development GO:0021549 2 0.017
regulation of multi organism process GO:0043900 157 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
cardiovascular system development GO:0072358 262 0.017
regulation of transferase activity GO:0051338 355 0.017
protein sumoylation GO:0016925 25 0.017
response to organic cyclic compound GO:0014070 204 0.017
embryo development GO:0009790 123 0.017
actin filament organization GO:0007015 128 0.017
positive regulation of protein complex assembly GO:0031334 86 0.017
mitotic spindle elongation GO:0000022 4 0.017
regulation of neuron differentiation GO:0045664 70 0.017
protein k11 linked ubiquitination GO:0070979 24 0.017
Rat
divalent metal ion transport GO:0070838 152 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
tripartite regional subdivision GO:0007351 2 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
defense response GO:0006952 315 0.016
dna packaging GO:0006323 77 0.016
response to ionizing radiation GO:0010212 65 0.016
Rat
positive regulation of phosphorylation GO:0042327 394 0.016
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
histone monoubiquitination GO:0010390 20 0.016
regulation of protein maturation GO:1903317 150 0.016
viral life cycle GO:0019058 132 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
regulation of transmembrane transport GO:0034762 139 0.016
wnt signaling pathway GO:0016055 156 0.016
mitotic cell cycle process GO:1903047 286 0.015
cell activation GO:0001775 213 0.015
meiotic chromosome segregation GO:0045132 4 0.015
regulation of protein polymerization GO:0032271 63 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
positive regulation of actin filament polymerization GO:0030838 38 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
negative regulation of transport GO:0051051 176 0.015
regulation of ion transmembrane transport GO:0034765 132 0.015
mitotic cell cycle GO:0000278 326 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
response to cytokine GO:0034097 232 0.014
response to hormone GO:0009725 175 0.014
positive regulation of locomotion GO:0040017 186 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
cell cycle checkpoint GO:0000075 117 0.014
intracellular protein transport GO:0006886 270 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
positive regulation of protein polymerization GO:0032273 45 0.014
protein acetylation GO:0006473 116 0.014
regulation of androgen receptor signaling pathway GO:0060765 18 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
neurogenesis GO:0022008 169 0.014
regulation of immune effector process GO:0002697 91 0.014
blood vessel development GO:0001568 172 0.014
defense response to other organism GO:0098542 129 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
regulation of cellular component movement GO:0051270 334 0.014
defense response to virus GO:0051607 71 0.014
retrograde transport endosome to golgi GO:0042147 45 0.014
regulation of viral transcription GO:0046782 34 0.013
actin polymerization or depolymerization GO:0008154 56 0.013
carbohydrate metabolic process GO:0005975 207 0.013
cellular response to lipid GO:0071396 127 0.013
response to other organism GO:0051707 261 0.013
ossification GO:0001503 121 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
glycoprotein metabolic process GO:0009100 110 0.013
regulation of metal ion transport GO:0010959 120 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
retina layer formation GO:0010842 3 0.013
cell proliferation involved in heart valve development GO:2000793 1 0.013
generation of neurons GO:0048699 152 0.013
protein oligomerization GO:0051259 173 0.013
regulation of cell cycle process GO:0010564 266 0.013
cation transmembrane transport GO:0098655 238 0.013
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.013
response to external biotic stimulus GO:0043207 261 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
response to virus GO:0009615 126 0.012
interaction with host GO:0051701 42 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
peptidyl lysine modification GO:0018205 144 0.012
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.012
regulation of cytokine production GO:0001817 232 0.012
double strand break repair GO:0006302 101 0.012
response to drug GO:0042493 81 0.012
single organism nuclear import GO:1902593 104 0.012
regulation of secretion by cell GO:1903530 177 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
positive regulation of catabolic process GO:0009896 310 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
entry into host GO:0044409 25 0.012
response to lipid GO:0033993 206 0.012
regulation of actin polymerization or depolymerization GO:0008064 56 0.012
blood vessel morphogenesis GO:0048514 162 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
viral gene expression GO:0019080 35 0.012
regulation of cell development GO:0060284 161 0.012
regulation of cartilage development GO:0061035 12 0.012
leukocyte activation GO:0045321 164 0.012
positive regulation of jnk cascade GO:0046330 52 0.012
sensory organ development GO:0007423 52 0.012
embryonic eye morphogenesis GO:0048048 2 0.011
maintenance of location GO:0051235 112 0.011
rna splicing GO:0008380 131 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
oogenesis GO:0048477 2 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
cellular amine metabolic process GO:0044106 41 0.011
connective tissue development GO:0061448 39 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
regulation of actin filament polymerization GO:0030833 50 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
nerve development GO:0021675 4 0.011
mitotic cell cycle checkpoint GO:0007093 68 0.011
single organism cellular localization GO:1902580 332 0.011
neural tube formation GO:0001841 3 0.011
regulation of leukocyte activation GO:0002694 115 0.011
blastocyst development GO:0001824 3 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
cell adhesion GO:0007155 325 0.011
positive regulation of immune system process GO:0002684 283 0.011
negative regulation of gene silencing by rna GO:0060967 3 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
negative regulation of protein modification process GO:0031400 200 0.011
sister chromatid segregation GO:0000819 54 0.011
regulation of calcium ion transport GO:0051924 79 0.011
regulation of binding GO:0051098 111 0.011
regulation of dna metabolic process GO:0051052 153 0.011
system process GO:0003008 349 0.011
negative regulation of immune system process GO:0002683 136 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
mrna processing GO:0006397 133 0.011
positive regulation of developmental process GO:0051094 314 0.011
organelle assembly GO:0070925 176 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
actin filament based process GO:0030029 224 0.011
negative regulation of protein ubiquitination GO:0031397 35 0.011
skeletal system development GO:0001501 79 0.010
protein modification by small protein removal GO:0070646 92 0.010
response to growth factor GO:0070848 205 0.010
negative regulation of kinase activity GO:0033673 106 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.010
regulation of protein kinase activity GO:0045859 289 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
meiosis i GO:0007127 4 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
pattern specification process GO:0007389 43 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
actin nucleation GO:0045010 21 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
visual behavior GO:0007632 2 0.010
regulation of secretion GO:0051046 194 0.010
protein processing GO:0016485 226 0.010
interleukin 2 secretion GO:0070970 3 0.010

RNF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.033
eye and adnexa disease DOID:1492 150 0.033
nervous system disease DOID:863 431 0.033
eye disease DOID:5614 149 0.020
retinal disease DOID:5679 118 0.017
retinal degeneration DOID:8466 89 0.017