|
|
establishment of protein localization to endoplasmic reticulum membrane
|
GO:0097051 |
3 |
0.980
|
|
|
|
endoplasmic reticulum tubular network organization
|
GO:0071786 |
8 |
0.907
|
|
|
|
golgi vesicle fusion to target membrane
|
GO:0048210 |
2 |
0.804
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.769
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.735
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.539
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.535
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.488
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.485
|
Fly |
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.480
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.480
|
|
|
|
endoplasmic reticulum organization
|
GO:0007029 |
20 |
0.467
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.461
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.457
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.438
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.436
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.426
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.424
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.408
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.405
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.386
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.384
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.344
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.340
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.338
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.337
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.318
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.315
|
|
|
|
protein localization to peroxisome
|
GO:0072662 |
15 |
0.307
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.304
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.304
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.299
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.298
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.298
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.298
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.292
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.290
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.290
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.287
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.274
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.267
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.266
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.263
|
|
|
|
protein targeting to peroxisome
|
GO:0006625 |
15 |
0.260
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.260
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.259
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.253
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.245
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.243
|
|
|
|
vesicle docking involved in exocytosis
|
GO:0006904 |
3 |
0.242
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.241
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.239
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.235
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.233
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.226
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.221
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.219
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.219
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.215
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.208
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.202
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.200
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.199
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.195
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.194
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.194
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.191
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.188
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.186
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.183
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.176
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.173
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.172
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.171
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.171
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.169
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.169
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.168
|
|
|
|
establishment of protein localization to peroxisome
|
GO:0072663 |
15 |
0.167
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.163
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.161
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.161
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.157
|
|
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.153
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.153
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.153
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.153
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.153
|
|
|
|
unidimensional cell growth
|
GO:0009826 |
1 |
0.151
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.151
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.151
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.144
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.142
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.140
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.140
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.138
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.137
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.136
|
|
|
|
growth
|
GO:0040007 |
202 |
0.134
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.133
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.132
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.128
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.127
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.126
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.126
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.125
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.125
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.124
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
17 |
0.123
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.122
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.122
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.120
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.119
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.117
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.116
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.114
|
|
|
|
corticotropin secretion
|
GO:0051458 |
2 |
0.114
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.114
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.114
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.112
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.111
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.110
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.109
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.108
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.104
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.104
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.104
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.104
|
|
|
|
golgi inheritance
|
GO:0048313 |
2 |
0.103
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.103
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.102
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.101
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.100
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.098
|
Fly |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.098
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.097
|
|
|
|
system process
|
GO:0003008 |
349 |
0.097
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.096
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.095
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.095
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.094
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.094
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.092
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.092
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.091
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.091
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.090
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.089
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.087
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.087
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.087
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.086
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.085
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.085
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.084
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.084
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.084
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.084
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.084
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.083
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.083
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.083
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.081
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.080
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.080
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.079
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.079
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.077
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.077
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.076
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.076
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.074
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.074
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.073
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.073
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.071
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.069
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.067
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.067
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.067
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.067
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.066
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.066
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.065
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.065
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.064
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.064
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.064
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.063
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.063
|
Human |
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.063
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.062
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.062
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.062
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.061
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.060
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.060
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.060
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.059
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.059
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.059
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.059
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.059
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.058
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.058
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.058
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.057
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.056
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.056
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.056
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.056
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.056
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.055
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.055
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.055
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.055
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.055
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.055
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.055
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.054
|
|
|
|
regulation of corticotropin secretion
|
GO:0051459 |
2 |
0.054
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.053
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.053
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.053
|
|
|
|
protein kinase a signaling
|
GO:0010737 |
9 |
0.053
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.053
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.053
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.052
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.051
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.051
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.051
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.051
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.051
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.051
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.050
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.050
|
Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.050
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.050
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.049
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.049
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.049
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.049
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.049
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.048
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.048
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.048
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.047
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.047
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.047
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.047
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.046
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.046
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.046
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.046
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.046
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.046
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.045
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.045
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.045
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.045
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.045
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.045
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.044
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.044
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.044
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.044
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.044
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.044
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.043
|
|
|
|
protein transmembrane transport
|
GO:0071806 |
25 |
0.043
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.042
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.042
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.042
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.041
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.041
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.041
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.041
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.041
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.041
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.040
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.040
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.040
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.040
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.040
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.040
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.040
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.039
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.039
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.039
|
Fly |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.039
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.039
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.038
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.038
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.038
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.038
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.038
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.037
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.037
|
|
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.037
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.037
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.037
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.037
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.037
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.037
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.036
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.036
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.036
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.036
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.036
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.036
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.036
|
Fly |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.035
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.035
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.035
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.034
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.034
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.034
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.034
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.034
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.034
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.034
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.033
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.033
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.033
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.033
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.033
|
|
|
|
monocyte activation
|
GO:0042117 |
3 |
0.033
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.033
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.032
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.032
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.032
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.032
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.032
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.032
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.032
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.031
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.031
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.031
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.031
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.031
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.031
|
Fly |
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.031
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.031
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.031
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.031
|
|
|
|
poly n acetyllactosamine metabolic process
|
GO:0030309 |
2 |
0.031
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.031
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.031
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.031
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.031
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.031
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.030
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.030
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.030
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.030
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.030
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.030
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.030
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.029
|
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.029
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.029
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.029
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.029
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.029
|
Fly |
|
|
signal release
|
GO:0023061 |
70 |
0.028
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.028
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.028
|
Human Rat |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.028
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.028
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.027
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.027
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.027
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.027
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.027
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.027
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.027
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.026
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
12 |
0.026
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.026
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.026
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.026
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.026
|
|
|
|
establishment of blood brain barrier
|
GO:0060856 |
1 |
0.026
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.026
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.026
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.026
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.026
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.026
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.026
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.026
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.025
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.025
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.025
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.025
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.025
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.025
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.024
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.024
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.024
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
22 |
0.024
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.024
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.024
|
|
|
|
head development
|
GO:0060322 |
108 |
0.024
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.024
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.024
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.024
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.024
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.023
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.023
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.023
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.023
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.023
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.023
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.022
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.022
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.022
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.022
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.022
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.022
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.022
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.022
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.022
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.022
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.022
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.021
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.021
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.021
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.021
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.021
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.021
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.021
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.021
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.021
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.021
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.021
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.021
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.021
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.021
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.021
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.021
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.021
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.021
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.021
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.021
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.020
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.020
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.020
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.020
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.020
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.020
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.020
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.020
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.020
|
|
|
|
mitochondrion localization
|
GO:0051646 |
10 |
0.020
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.019
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.019
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.019
|
|
|
|
phosphatidylethanolamine biosynthetic process
|
GO:0006646 |
4 |
0.019
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.019
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.019
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.019
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.019
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.019
|
Fly |
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.019
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.019
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.019
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.019
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.019
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.019
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.018
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.018
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.018
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.018
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.018
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.018
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.018
|
|
