Homo sapiens

101 known processes

RPA2

replication protein A2, 32kDa

(Aliases: REPA2,RPA32)

RPA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna geometric change GO:0032392 32 0.999
Yeast
base excision repair GO:0006284 21 0.992
dna dependent dna replication GO:0006261 44 0.978
Yeast
leading strand elongation GO:0006272 1 0.963
dna duplex unwinding GO:0032508 30 0.955
Yeast
telomere maintenance via recombination GO:0000722 4 0.954
Yeast
dna strand elongation involved in dna replication GO:0006271 3 0.950
cellular response to dna damage stimulus GO:0006974 379 0.947
double strand break repair GO:0006302 101 0.918
dna conformation change GO:0071103 113 0.913
Yeast
dna repair GO:0006281 198 0.908
glycosyl compound catabolic process GO:1901658 413 0.861
purine nucleoside monophosphate catabolic process GO:0009128 158 0.786
telomere maintenance via telomerase GO:0007004 8 0.759
Yeast
reciprocal meiotic recombination GO:0007131 4 0.728
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.665
double strand break repair via homologous recombination GO:0000724 50 0.646
dna damage checkpoint GO:0000077 68 0.640
dna integrity checkpoint GO:0031570 71 0.611
atp catabolic process GO:0006200 157 0.589
chromatin modification GO:0016568 298 0.579
dna recombination GO:0006310 77 0.567
regulation of helicase activity GO:0051095 8 0.519
ribonucleoside monophosphate metabolic process GO:0009161 187 0.453
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.441
purine nucleotide catabolic process GO:0006195 405 0.440
purine ribonucleoside catabolic process GO:0046130 398 0.418
nucleoside catabolic process GO:0009164 408 0.401
mitotic cell cycle phase transition GO:0044772 162 0.382
rna dependent dna replication GO:0006278 16 0.377
Yeast
nucleotide excision repair GO:0006289 31 0.363
response to uv GO:0009411 73 0.348
cell cycle checkpoint GO:0000075 117 0.335
purine containing compound catabolic process GO:0072523 411 0.325
nucleoside monophosphate catabolic process GO:0009125 159 0.316
positive regulation of helicase activity GO:0051096 6 0.301
somatic diversification of immune receptors via somatic mutation GO:0002566 1 0.300
response to abiotic stimulus GO:0009628 336 0.293
histone h3 k4 methylation GO:0051568 27 0.283
mitotic dna damage checkpoint GO:0044773 28 0.282
recombinational repair GO:0000725 50 0.282
ribonucleoside catabolic process GO:0042454 406 0.282
dna strand elongation GO:0022616 5 0.282
ribonucleoside monophosphate catabolic process GO:0009158 158 0.274
dna replication GO:0006260 116 0.240
nucleoside phosphate catabolic process GO:1901292 412 0.231
sister chromatid cohesion GO:0007062 24 0.227
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.224
telomere maintenance GO:0000723 32 0.221
dna synthesis involved in dna repair GO:0000731 6 0.216
replication fork processing GO:0031297 13 0.192
purine nucleoside triphosphate catabolic process GO:0009146 392 0.189
mismatch repair GO:0006298 15 0.188
purine nucleoside catabolic process GO:0006152 398 0.180
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.179
mitotic cell cycle GO:0000278 326 0.178
protein alkylation GO:0008213 74 0.168
mitotic dna integrity checkpoint GO:0044774 30 0.168
cellular response to ionizing radiation GO:0071479 32 0.166
nucleotide catabolic process GO:0009166 408 0.162
purine nucleoside monophosphate metabolic process GO:0009126 186 0.156
histone methylation GO:0016571 60 0.154
organophosphate catabolic process GO:0046434 430 0.153
meiotic chromosome separation GO:0051307 3 0.152
ribonucleoside triphosphate metabolic process GO:0009199 412 0.150
histone lysine methylation GO:0034968 50 0.149
g2 dna damage checkpoint GO:0031572 26 0.149
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.148
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.145
histone modification GO:0016570 251 0.143
regulation of dna methylation GO:0044030 2 0.136
rna splicing GO:0008380 131 0.135
growth GO:0040007 202 0.134
ribonucleoside triphosphate catabolic process GO:0009203 391 0.134
dna unwinding involved in dna replication GO:0006268 2 0.114
Yeast
translesion synthesis GO:0019985 8 0.110
circulatory system development GO:0072359 262 0.108
response to oxygen containing compound GO:1901700 369 0.106
tissue homeostasis GO:0001894 63 0.101
positive regulation of hydrolase activity GO:0051345 331 0.099
dna biosynthetic process GO:0071897 40 0.097
negative regulation of cell cycle process GO:0010948 121 0.096
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.092
dna modification GO:0006304 27 0.091
immune system development GO:0002520 195 0.091
meiosis i GO:0007127 4 0.085
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.084
regulation of cell cycle GO:0051726 393 0.078
purine ribonucleotide catabolic process GO:0009154 404 0.077
production of molecular mediator of immune response GO:0002440 37 0.077
nucleoside triphosphate metabolic process GO:0009141 422 0.076
reciprocal dna recombination GO:0035825 4 0.076
Yeast
regulation of cellular response to stress GO:0080135 244 0.075
rna splicing via transesterification reactions GO:0000375 90 0.073
covalent chromatin modification GO:0016569 254 0.071
nervous system development GO:0007399 293 0.070
Fly
cellular response to abiotic stimulus GO:0071214 117 0.069
response to light stimulus GO:0009416 87 0.068
nucleoside triphosphate catabolic process GO:0009143 394 0.067
nucleoside monophosphate metabolic process GO:0009123 191 0.066
double strand break repair via single strand annealing GO:0045002 4 0.066
regulation of mitotic cell cycle GO:0007346 189 0.065
meiotic chromosome segregation GO:0045132 4 0.065
anatomical structure homeostasis GO:0060249 100 0.063
telomere organization GO:0032200 33 0.062
negative regulation of thymocyte apoptotic process GO:0070244 1 0.060
cell projection organization GO:0030030 252 0.059
cellular amine metabolic process GO:0044106 41 0.058
cellular component morphogenesis GO:0032989 314 0.057
vesicle mediated transport GO:0016192 371 0.056
cardiovascular system development GO:0072358 262 0.056
mrna processing GO:0006397 133 0.054
cell morphogenesis GO:0000902 296 0.054
cellular ketone metabolic process GO:0042180 80 0.053
regulation of cell cycle process GO:0010564 266 0.052
posttranscriptional regulation of gene expression GO:0010608 213 0.050
negative regulation of cell death GO:0060548 345 0.050
response to dietary excess GO:0002021 2 0.049
methylation GO:0032259 106 0.047
somatic hypermutation of immunoglobulin genes GO:0016446 1 0.046
intracellular mrna localization GO:0008298 1 0.046
reproductive process GO:0022414 106 0.046
negative regulation of mitotic cell cycle GO:0045930 102 0.045
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.045
negative regulation of cell cycle phase transition GO:1901988 89 0.042
dna replication initiation GO:0006270 6 0.042
multicellular organismal homeostasis GO:0048871 67 0.042
hematopoietic stem cell differentiation GO:0060218 4 0.042
mitotic recombination GO:0006312 8 0.042
Yeast
neuron differentiation GO:0030182 138 0.041
response to radiation GO:0009314 151 0.040
dna packaging GO:0006323 77 0.040
response to metal ion GO:0010038 84 0.040
cellular response to oxygen containing compound GO:1901701 276 0.040
atp metabolic process GO:0046034 176 0.040
segmentation GO:0035282 4 0.039
chromosome condensation GO:0030261 15 0.039
chromatin organization GO:0006325 351 0.039
cell cell signaling GO:0007267 155 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.036
response to inorganic substance GO:0010035 127 0.036
mitotic g2 dna damage checkpoint GO:0007095 7 0.035
negative regulation of secretion by cell GO:1903531 52 0.035
cell fate commitment GO:0045165 27 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.033
macromolecule methylation GO:0043414 97 0.032
homeostasis of number of cells GO:0048872 40 0.032
cell cycle phase transition GO:0044770 173 0.031
determination of adult lifespan GO:0008340 2 0.031
chordate embryonic development GO:0043009 34 0.030
behavior GO:0007610 112 0.030
intra s dna damage checkpoint GO:0031573 4 0.030
non recombinational repair GO:0000726 14 0.029
cellular response to radiation GO:0071478 65 0.029
cell development GO:0048468 328 0.029
hemopoiesis GO:0030097 180 0.029
post embryonic development GO:0009791 2 0.028
endocytosis GO:0006897 159 0.028
heart development GO:0007507 95 0.028
regulation of mitotic cell cycle phase transition GO:1901990 118 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
neurogenesis GO:0022008 169 0.027
Fly
response to heat GO:0009408 21 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
regulation of dna metabolic process GO:0051052 153 0.026
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.025
epithelium development GO:0060429 227 0.025
response to hormone GO:0009725 175 0.025
regulation of kinase activity GO:0043549 314 0.025
negative regulation of cell cycle GO:0045786 193 0.024
protein methylation GO:0006479 74 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
rna processing GO:0006396 255 0.022
protein ubiquitination GO:0016567 314 0.022
Yeast
hematopoietic or lymphoid organ development GO:0048534 186 0.022
cellular response to organic cyclic compound GO:0071407 127 0.022
internal peptidyl lysine acetylation GO:0018393 97 0.021
oogenesis GO:0048477 2 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
positive regulation of developmental process GO:0051094 314 0.021
response to other organism GO:0051707 261 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
cell projection morphogenesis GO:0048858 129 0.020
telomere maintenance via telomere lengthening GO:0010833 9 0.020
Yeast
nitrogen compound transport GO:0071705 191 0.020
cellular response to external stimulus GO:0071496 111 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
maintenance of dna repeat elements GO:0043570 4 0.019
engulfment of apoptotic cell GO:0043652 2 0.018
multicellular organismal aging GO:0010259 3 0.018
neuron projection development GO:0031175 106 0.018
regulation of transcription by chromatin organization GO:0034401 1 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.018
locomotory behavior GO:0007626 1 0.018
organic acid biosynthetic process GO:0016053 97 0.018
cell part morphogenesis GO:0032990 137 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
double strand break repair via nonhomologous end joining GO:0006303 10 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
g1 dna damage checkpoint GO:0044783 18 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
lagging strand elongation GO:0006273 3 0.016
mrna metabolic process GO:0016071 175 0.016
regulation of cytokine production GO:0001817 232 0.016
mitotic g1 dna damage checkpoint GO:0031571 17 0.016
response to extracellular stimulus GO:0009991 85 0.016
embryo development GO:0009790 123 0.016
peptidyl lysine modification GO:0018205 144 0.016
response to nutrient levels GO:0031667 81 0.015
dna methylation or demethylation GO:0044728 19 0.015
dna double strand break processing GO:0000729 10 0.015
histone exchange GO:0043486 3 0.015
regulation of peptidase activity GO:0052547 180 0.015
apoptotic signaling pathway GO:0097190 268 0.015
mitotic g2 m transition checkpoint GO:0044818 9 0.015
nuclear migration GO:0007097 1 0.015
membrane organization GO:0061024 292 0.015
response to calcium ion GO:0051592 46 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regeneration GO:0031099 4 0.015
mrna splicing via spliceosome GO:0000398 89 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
blastocyst development GO:0001824 3 0.014
replicative cell aging GO:0001302 3 0.014
organelle localization GO:0051640 84 0.014
transmembrane transport GO:0055085 399 0.014
regulation of mrna metabolic process GO:1903311 53 0.014
response to cytokine GO:0034097 232 0.014
peptidyl serine modification GO:0018209 106 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
negative regulation of growth GO:0045926 97 0.014
rna interference GO:0016246 4 0.013
protein acetylation GO:0006473 116 0.013
ribonucleoprotein complex assembly GO:0022618 78 0.013
cell aging GO:0007569 52 0.013
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.013
negative regulation of meiotic cell cycle GO:0051447 2 0.013
protein acylation GO:0043543 138 0.013
protein oligomerization GO:0051259 173 0.013
negative regulation of transferase activity GO:0051348 124 0.013
cell type specific apoptotic process GO:0097285 125 0.013
response to ionizing radiation GO:0010212 65 0.012
amine metabolic process GO:0009308 44 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
peptidyl glutamic acid modification GO:0018200 4 0.012
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.012
cellular response to nutrient levels GO:0031669 69 0.012
regulation of growth rate GO:0040009 1 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
wnt signaling pathway GO:0016055 156 0.012
cell division GO:0051301 168 0.011
hindbrain development GO:0030902 3 0.011
small molecule biosynthetic process GO:0044283 157 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
regulation of rna splicing GO:0043484 62 0.011
dna alkylation GO:0006305 7 0.011
regulation of gtpase activity GO:0043087 180 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of dna replication GO:0006275 68 0.011
neuron development GO:0048666 113 0.011
compound eye development GO:0048749 1 0.011
maintenance of location GO:0051235 112 0.010
cellular response to lipid GO:0071396 127 0.010
taxis GO:0042330 157 0.010
dna catabolic process endonucleolytic GO:0000737 37 0.010
cytoplasmic transport GO:0016482 379 0.010
response to organic cyclic compound GO:0014070 204 0.010
microtubule based process GO:0007017 210 0.010
ribonucleotide catabolic process GO:0009261 405 0.010

RPA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.016
inherited metabolic disorder DOID:655 242 0.015
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012
eye and adnexa disease DOID:1492 150 0.012
auditory system disease DOID:2742 53 0.011
nonsyndromic deafness DOID:0050563 50 0.011