Homo sapiens

153 known processes

RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

(Aliases: MSK2,RSK-B)

RPS6KA4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 78 0.448
ras protein signal transduction GO:0007265 73 0.373
gtp catabolic process GO:0006184 237 0.335
cartilage condensation GO:0001502 1 0.290
nucleoside triphosphate metabolic process GO:0009141 422 0.188
glycosyl compound catabolic process GO:1901658 413 0.188
purine nucleotide catabolic process GO:0006195 405 0.171
cellular amine metabolic process GO:0044106 41 0.171
purine ribonucleoside catabolic process GO:0046130 398 0.168
regulation of small gtpase mediated signal transduction GO:0051056 156 0.168
purine ribonucleotide catabolic process GO:0009154 404 0.165
nucleoside triphosphate catabolic process GO:0009143 394 0.159
response to salt stress GO:0009651 3 0.147
rho protein signal transduction GO:0007266 26 0.145
negative regulation of catalytic activity GO:0043086 335 0.136
Human
ribonucleoside catabolic process GO:0042454 406 0.133
purine nucleoside catabolic process GO:0006152 398 0.132
nucleoside catabolic process GO:0009164 408 0.130
positive regulation of hydrolase activity GO:0051345 331 0.129
positive regulation of catabolic process GO:0009896 310 0.129
guanosine containing compound catabolic process GO:1901069 239 0.126
ribonucleotide catabolic process GO:0009261 405 0.125
regulation of cellular amino acid metabolic process GO:0006521 6 0.122
regulation of ras protein signal transduction GO:0046578 155 0.119
negative regulation of protein metabolic process GO:0051248 391 0.116
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.116
organophosphate catabolic process GO:0046434 430 0.115
regulation of gtp catabolic process GO:0033124 180 0.115
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.114
signal transduction by phosphorylation GO:0023014 297 0.112
positive regulation of nucleotide catabolic process GO:0030813 185 0.110
arachidonic acid metabolic process GO:0019369 14 0.110
regulation of protein serine threonine kinase activity GO:0071900 179 0.108
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.102
purine ribonucleoside metabolic process GO:0046128 437 0.102
positive regulation of cellular catabolic process GO:0031331 284 0.102
positive regulation of gtp catabolic process GO:0033126 166 0.101
positive regulation of protein phosphorylation GO:0001934 313 0.101
regulation of mapk cascade GO:0043408 262 0.100
regulation of nucleotide catabolic process GO:0030811 205 0.097
regulation of protein kinase activity GO:0045859 289 0.094
ribonucleoside triphosphate catabolic process GO:0009203 391 0.090
purine nucleoside triphosphate metabolic process GO:0009144 412 0.089
purine nucleoside triphosphate catabolic process GO:0009146 392 0.089
nucleoside phosphate catabolic process GO:1901292 412 0.088
regulation of gtpase activity GO:0043087 180 0.088
positive regulation of nucleotide metabolic process GO:0045981 230 0.088
post embryonic development GO:0009791 2 0.087
Worm
mapk cascade GO:0000165 288 0.087
multicellular organismal aging GO:0010259 3 0.086
female gamete generation GO:0007292 2 0.084
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.084
purine containing compound catabolic process GO:0072523 411 0.084
guanosine containing compound metabolic process GO:1901068 244 0.083
positive regulation of gtpase activity GO:0043547 166 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.079
cell morphogenesis GO:0000902 296 0.076
gtp metabolic process GO:0046039 239 0.075
long chain fatty acid metabolic process GO:0001676 30 0.074
positive regulation of apoptotic process GO:0043065 246 0.074
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.074
positive regulation of ras gtpase activity GO:0032320 117 0.072
enzyme linked receptor protein signaling pathway GO:0007167 303 0.071
Human
regulation of transferase activity GO:0051338 355 0.071
response to abiotic stimulus GO:0009628 336 0.071
regulation of cellular amine metabolic process GO:0033238 11 0.070
regulation of rho protein signal transduction GO:0035023 79 0.069
regulation of purine nucleotide catabolic process GO:0033121 205 0.069
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.068
Human
cellular ketone metabolic process GO:0042180 80 0.067
nucleotide catabolic process GO:0009166 408 0.066
oogenesis GO:0048477 2 0.065
Fly
regulation of cytokine production GO:0001817 232 0.064
response to cytokine GO:0034097 232 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.063
defense response GO:0006952 315 0.063
dephosphorylation GO:0016311 209 0.062
negative regulation of phosphorus metabolic process GO:0010563 267 0.061
determination of adult lifespan GO:0008340 2 0.060
stress activated mapk cascade GO:0051403 93 0.060
negative regulation of protein phosphorylation GO:0001933 140 0.058
cell adhesion GO:0007155 325 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.058
regulation of ras gtpase activity GO:0032318 128 0.057
cellular response to abiotic stimulus GO:0071214 117 0.056
positive regulation of cellular component organization GO:0051130 376 0.055
cellular amino acid metabolic process GO:0006520 116 0.054
immune response regulating signaling pathway GO:0002764 97 0.053
cellular component morphogenesis GO:0032989 314 0.053
nervous system development GO:0007399 293 0.052
protein autophosphorylation GO:0046777 123 0.052
Fly
regulation of map kinase activity GO:0043405 108 0.052
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.052
negative regulation of phosphate metabolic process GO:0045936 267 0.051
monocarboxylic acid metabolic process GO:0032787 185 0.051
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.051
regulation of kinase activity GO:0043549 314 0.050
response to biotic stimulus GO:0009607 276 0.050
cardiovascular system development GO:0072358 262 0.049
regulation of nucleotide metabolic process GO:0006140 269 0.049
positive regulation of nucleoside metabolic process GO:0045979 186 0.048
biological adhesion GO:0022610 331 0.047
regulation of cytoskeleton organization GO:0051493 177 0.047
cytokine production GO:0001816 247 0.046
innate immune response GO:0045087 178 0.046
p38mapk cascade GO:0038066 9 0.045
immune response GO:0006955 307 0.044
peptidyl serine phosphorylation GO:0018105 101 0.044
regulation of cellular response to stress GO:0080135 244 0.044
response to other organism GO:0051707 261 0.044
system process GO:0003008 349 0.044
regulation of erk1 and erk2 cascade GO:0070372 99 0.044
response to growth factor GO:0070848 205 0.043
Human
oocyte development GO:0048599 1 0.043
cellular response to external stimulus GO:0071496 111 0.043
cell activation GO:0001775 213 0.042
Human
protein catabolic process GO:0030163 325 0.042
negative regulation of intracellular signal transduction GO:1902532 183 0.041
regulation of protein localization GO:0032880 296 0.041
jnk cascade GO:0007254 80 0.041
single organism carbohydrate metabolic process GO:0044723 193 0.041
oocyte differentiation GO:0009994 2 0.041
activation of immune response GO:0002253 114 0.040
actin filament based process GO:0030029 224 0.040
response to oxygen containing compound GO:1901700 369 0.040
Human
endomembrane system organization GO:0010256 196 0.040
regulation of rho gtpase activity GO:0032319 66 0.039
peptidyl serine modification GO:0018209 106 0.039
positive regulation of mapk cascade GO:0043410 190 0.039
carbohydrate metabolic process GO:0005975 207 0.039
negative regulation of phosphorylation GO:0042326 174 0.039
cellular response to oxygen containing compound GO:1901701 276 0.039
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.039
Human
regulation of cellular component size GO:0032535 82 0.038
response to fungus GO:0009620 4 0.038
locomotory behavior GO:0007626 1 0.038
regulation of cellular component biogenesis GO:0044087 281 0.038
regulation of stress activated mapk cascade GO:0032872 84 0.038
amine metabolic process GO:0009308 44 0.038
positive regulation of cell differentiation GO:0045597 211 0.037
erk1 and erk2 cascade GO:0070371 104 0.036
anion transport GO:0006820 161 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.036
actin cytoskeleton organization GO:0030036 207 0.035
negative regulation of transferase activity GO:0051348 124 0.035
negative regulation of protein modification process GO:0031400 200 0.035
regulation of response to external stimulus GO:0032101 222 0.035
positive regulation of protein kinase activity GO:0045860 190 0.034
innate immune response activating signal transduction GO:0002758 48 0.034
morphogenesis of embryonic epithelium GO:0016331 4 0.034
neurological system process GO:0050877 163 0.033
positive regulation of phosphorylation GO:0042327 394 0.033
vesicle mediated transport GO:0016192 371 0.033
jun phosphorylation GO:0007258 28 0.032
regulation of anatomical structure size GO:0090066 101 0.032
protein localization to organelle GO:0033365 280 0.032
cdc42 protein signal transduction GO:0032488 4 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.031
Human
lipid metabolic process GO:0006629 381 0.031
activation of mapk activity GO:0000187 45 0.031
defense response to fungus GO:0050832 4 0.031
regulation of defense response GO:0031347 154 0.030
response to external biotic stimulus GO:0043207 261 0.030
regulation of response to wounding GO:1903034 101 0.030
brain development GO:0007420 97 0.030
growth GO:0040007 202 0.030
tissue morphogenesis GO:0048729 96 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
activation of protein kinase activity GO:0032147 90 0.029
response to radiation GO:0009314 151 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
single organism cellular localization GO:1902580 332 0.029
positive regulation of cell death GO:0010942 263 0.029
Human
positive regulation of rho gtpase activity GO:0032321 56 0.028
hematopoietic or lymphoid organ development GO:0048534 186 0.028
circulatory system development GO:0072359 262 0.028
response to molecule of bacterial origin GO:0002237 82 0.028
memory GO:0007613 3 0.028
regulation of jnk cascade GO:0046328 73 0.028
hyperosmotic response GO:0006972 4 0.028
peptidyl threonine modification GO:0018210 45 0.028
mitotic cell cycle GO:0000278 326 0.027
Human
positive regulation of immune response GO:0050778 159 0.027
regulation of cellular component movement GO:0051270 334 0.027
epithelium migration GO:0090132 119 0.027
peptidyl lysine acetylation GO:0018394 101 0.027
regulation of immune response GO:0050776 201 0.027
regeneration GO:0031099 4 0.027
nuclear transport GO:0051169 179 0.026
regulation of meiotic cell cycle GO:0051445 4 0.026
positive regulation of immune system process GO:0002684 283 0.026
cellular lipid metabolic process GO:0044255 303 0.026
anterior posterior axis specification GO:0009948 2 0.025
positive regulation of protein transport GO:0051222 135 0.025
negative regulation of protein kinase activity GO:0006469 98 0.025
response to uv GO:0009411 73 0.025
activation of innate immune response GO:0002218 55 0.025
cellular protein complex assembly GO:0043623 188 0.025
positive regulation of locomotion GO:0040017 186 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
negative regulation of organelle organization GO:0010639 126 0.025
microtubule based process GO:0007017 210 0.025
positive regulation of transport GO:0051050 336 0.025
cell part morphogenesis GO:0032990 137 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
translation GO:0006412 132 0.024
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
Human
regulation of cell cycle GO:0051726 393 0.024
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.024
response to inorganic substance GO:0010035 127 0.024
response to bacterium GO:0009617 144 0.024
secretion GO:0046903 254 0.024
head development GO:0060322 108 0.024
cell morphogenesis involved in differentiation GO:0000904 144 0.024
positive regulation of cell size GO:0045793 3 0.024
regulation of multi organism process GO:0043900 157 0.023
positive regulation of defense response GO:0031349 87 0.023
positive regulation of cell development GO:0010720 92 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
response to wounding GO:0009611 168 0.023
regulation of intracellular transport GO:0032386 195 0.023
negative regulation of kinase activity GO:0033673 106 0.023
neuromuscular junction development GO:0007528 3 0.023
immune response activating signal transduction GO:0002757 90 0.022
segmentation GO:0035282 4 0.022
negative regulation of erk1 and erk2 cascade GO:0070373 14 0.022
cell development GO:0048468 328 0.022
Fly
defense response to other organism GO:0098542 129 0.022
cell projection organization GO:0030030 252 0.022
positive regulation of cytokine production GO:0001819 167 0.022
positive regulation of cell motility GO:2000147 177 0.022
regulation of cell morphogenesis GO:0022604 153 0.021
epithelium development GO:0060429 227 0.021
cytokine mediated signaling pathway GO:0019221 109 0.021
single organismal cell cell adhesion GO:0016337 148 0.021
positive regulation of transferase activity GO:0051347 227 0.021
rab protein signal transduction GO:0032482 4 0.021
regulation of translation GO:0006417 89 0.021
Human
protein dephosphorylation GO:0006470 81 0.021
peptidyl threonine phosphorylation GO:0018107 41 0.021
response to mechanical stimulus GO:0009612 51 0.021
embryonic camera type eye development GO:0031076 2 0.021
organ formation GO:0048645 3 0.020
atp catabolic process GO:0006200 157 0.020
response to lipid GO:0033993 206 0.020
positive regulation of map kinase activity GO:0043406 80 0.020
positive regulation of rab gtpase activity GO:0032851 39 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.020
actin filament organization GO:0007015 128 0.020
regulation of protein binding GO:0043393 66 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
Human
cellular response to lipid GO:0071396 127 0.020
positive regulation of developmental process GO:0051094 314 0.020
regulation of actin filament based process GO:0032970 141 0.019
bmp signaling pathway GO:0030509 49 0.019
regulation of actin cytoskeleton organization GO:0032956 116 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
heart development GO:0007507 95 0.019
regulation of locomotion GO:0040012 329 0.019
organ morphogenesis GO:0009887 147 0.019
oocyte maturation GO:0001556 1 0.019
cell cell junction organization GO:0045216 69 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
histone modification GO:0016570 251 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
response to light stimulus GO:0009416 87 0.019
fatty acid metabolic process GO:0006631 115 0.019
lymphocyte activation GO:0046649 133 0.019
response to nitrosative stress GO:0051409 4 0.019
vasculature development GO:0001944 181 0.019
regulation of binding GO:0051098 111 0.019
cellular response to hormone stimulus GO:0032870 125 0.018
Human
glycerolipid metabolic process GO:0046486 107 0.018
positive regulation of kinase activity GO:0033674 204 0.018
negative regulation of developmental process GO:0051093 247 0.018
regulation of peptidase activity GO:0052547 180 0.018
Human
cellular response to mechanical stimulus GO:0071260 39 0.018
hemopoiesis GO:0030097 180 0.018
cytoplasmic transport GO:0016482 379 0.018
covalent chromatin modification GO:0016569 254 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
regulation of cell differentiation GO:0045595 393 0.018
secretion by cell GO:0032940 226 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
sensory perception of pain GO:0019233 4 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
cardiac muscle contraction GO:0060048 34 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
cell projection morphogenesis GO:0048858 129 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
mitotic cell cycle process GO:1903047 286 0.018
Human
response to lipopolysaccharide GO:0032496 70 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
regulation of cell cycle process GO:0010564 266 0.018
negative regulation of cell cycle GO:0045786 193 0.018
Human
tissue migration GO:0090130 119 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
Human
regulation of phosphatase activity GO:0010921 81 0.018
response to oxidative stress GO:0006979 121 0.018
membrane organization GO:0061024 292 0.018
regulation of chromosome organization GO:0033044 103 0.018
tripartite regional subdivision GO:0007351 2 0.018
connective tissue development GO:0061448 39 0.017
negative regulation of mapk cascade GO:0043409 56 0.017
internal protein amino acid acetylation GO:0006475 101 0.017
positive regulation of innate immune response GO:0045089 79 0.017
cellular response to arsenic containing substance GO:0071243 4 0.017
regulation of innate immune response GO:0045088 97 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
negative regulation of cytoskeleton organization GO:0051494 45 0.017
central nervous system neuron axonogenesis GO:0021955 3 0.017
regulation of dna metabolic process GO:0051052 153 0.017
generation of neurons GO:0048699 152 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
peptidyl lysine modification GO:0018205 144 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.017
positive regulation of intracellular protein transport GO:0090316 76 0.017
single organism membrane organization GO:0044802 268 0.017
cell growth GO:0016049 160 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
apoptotic signaling pathway GO:0097190 268 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
cell junction maintenance GO:0034331 4 0.017
behavior GO:0007610 112 0.017
neuron projection development GO:0031175 106 0.017
positive regulation of intracellular transport GO:0032388 104 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
single organism cell adhesion GO:0098602 179 0.016
maintenance of location GO:0051235 112 0.016
nitrogen compound transport GO:0071705 191 0.016
regulation of autophagy GO:0010506 52 0.016
protein localization to nucleus GO:0034504 136 0.016
tube closure GO:0060606 3 0.016
intracellular protein transport GO:0006886 270 0.016
pattern recognition receptor signaling pathway GO:0002221 48 0.016
protein oligomerization GO:0051259 173 0.016
negative regulation of catabolic process GO:0009895 104 0.016
positive regulation of organelle organization GO:0010638 195 0.016
cell fate determination GO:0001709 3 0.016
regulation of secretion by cell GO:1903530 177 0.016
nuclear division GO:0000280 128 0.016
Fly
circulatory system process GO:0003013 113 0.016
defense response to gram positive bacterium GO:0050830 29 0.016
organic anion transport GO:0015711 103 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
cation transport GO:0006812 331 0.015
positive regulation of neurogenesis GO:0050769 49 0.015
cellular response to biotic stimulus GO:0071216 71 0.015
regulation of growth GO:0040008 165 0.015
regulation of dephosphorylation GO:0035303 96 0.015
regulation of secretion GO:0051046 194 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
blood vessel morphogenesis GO:0048514 162 0.015
leukocyte activation GO:0045321 164 0.015
t cell differentiation in thymus GO:0033077 4 0.015
regulation of cell motility GO:2000145 299 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
negative regulation of immune system process GO:0002683 136 0.015
positive regulation of cell migration GO:0030335 172 0.015
skeletal system development GO:0001501 79 0.015
immune system development GO:0002520 195 0.015
neural tube closure GO:0001843 3 0.015
cellular protein catabolic process GO:0044257 261 0.015
multi organism cellular process GO:0044764 156 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
blastoderm segmentation GO:0007350 2 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.015
protein targeting GO:0006605 187 0.015
negative regulation of multi organism process GO:0043901 92 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
blood vessel development GO:0001568 172 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
protein maturation GO:0051604 233 0.014
Human
response to axon injury GO:0048678 1 0.014
neurogenesis GO:0022008 169 0.014
autophagy GO:0006914 88 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
central nervous system projection neuron axonogenesis GO:0021952 3 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
negative regulation of map kinase activity GO:0043407 27 0.014
regulation of nervous system development GO:0051960 88 0.014
oxidation reduction process GO:0055114 396 0.014
nuclear export GO:0051168 69 0.014
spermatid differentiation GO:0048515 4 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
cell substrate adhesion GO:0031589 132 0.014
cellular response to lipopolysaccharide GO:0071222 57 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
Human
endocytosis GO:0006897 159 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
cellular homeostasis GO:0019725 196 0.014
regulation of protein transport GO:0051223 213 0.014
chromatin organization GO:0006325 351 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
Human
viral process GO:0016032 146 0.014
glycoprotein metabolic process GO:0009100 110 0.014
regulation of cell growth GO:0001558 135 0.014
cation homeostasis GO:0055080 189 0.013
negative regulation of binding GO:0051100 57 0.013
nuclear import GO:0051170 106 0.013
chemotaxis GO:0006935 157 0.013
negative regulation of cell death GO:0060548 345 0.013
Human
regulation of protein complex assembly GO:0043254 147 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
Human
response to extracellular stimulus GO:0009991 85 0.013
regulation of cell development GO:0060284 161 0.013
central nervous system development GO:0007417 123 0.013
neuron differentiation GO:0030182 138 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
tumor necrosis factor production GO:0032640 43 0.013
regulation of rab gtpase activity GO:0032313 39 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
Human
interspecies interaction between organisms GO:0044419 156 0.013
regulation of proteolysis GO:0030162 293 0.013
Human
mitotic nuclear division GO:0007067 119 0.013
associative learning GO:0008306 1 0.013
wnt signaling pathway GO:0016055 156 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
chromatin modification GO:0016568 298 0.013
response to nutrient levels GO:0031667 81 0.013
cell junction assembly GO:0034329 67 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
rna interference GO:0016246 4 0.013
establishment of planar polarity GO:0001736 3 0.013
plasma membrane organization GO:0007009 115 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
regulation of protein polymerization GO:0032271 63 0.013
primary neural tube formation GO:0014020 3 0.013
sensory organ development GO:0007423 52 0.012
unsaturated fatty acid metabolic process GO:0033559 37 0.012
atp metabolic process GO:0046034 176 0.012
peptidyl tyrosine dephosphorylation GO:0035335 36 0.012
response to hormone GO:0009725 175 0.012
Human
t cell activation GO:0042110 99 0.012
compound eye development GO:0048749 1 0.012
negative regulation of response to external stimulus GO:0032102 83 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
metal ion transport GO:0030001 272 0.012
neurotransmitter secretion GO:0007269 4 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
positive regulation of secretion GO:0051047 116 0.012
adult locomotory behavior GO:0008344 1 0.012
negative regulation of protein maturation GO:1903318 142 0.012
Human
phospholipid metabolic process GO:0006644 99 0.012
tissue regeneration GO:0042246 3 0.012
cellular cation homeostasis GO:0030003 163 0.012
ion homeostasis GO:0050801 230 0.012
single organism reproductive process GO:0044702 98 0.012
Fly
sensory perception of smell GO:0007608 2 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
lipid localization GO:0010876 106 0.012
regulation of rab protein signal transduction GO:0032483 39 0.012
sequestering of calcium ion GO:0051208 17 0.012
negative regulation of protein processing GO:0010955 142 0.012
Human
leukocyte differentiation GO:0002521 98 0.012
regulation of cell adhesion GO:0030155 166 0.012
cell projection assembly GO:0030031 126 0.011
positive regulation of rac gtpase activity GO:0032855 31 0.011
response to reactive oxygen species GO:0000302 61 0.011
wound healing GO:0042060 115 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of proteolysis GO:0045862 142 0.011
protein import GO:0017038 130 0.011
embryo development GO:0009790 123 0.011
Worm
taxis GO:0042330 157 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011

RPS6KA4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.038
nervous system disease DOID:863 431 0.038
musculoskeletal system disease DOID:17 223 0.026
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.022
central nervous system disease DOID:331 186 0.017
myopathy DOID:423 104 0.014
muscular disease DOID:0080000 114 0.014
muscle tissue disease DOID:66 113 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
connective tissue disease DOID:65 109 0.013
disease of metabolism DOID:0014667 295 0.013
inherited metabolic disorder DOID:655 242 0.013
organ system cancer DOID:0050686 164 0.013
retinal disease DOID:5679 118 0.011